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Journal : The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy

Correlation between Apolipoprotein B (Apob) Level and Non Alcoholic Fatty Liver in Type 2 Diabetes Mellitus with Metabolic Syndrome Nugroho, Tejo; Harmono, Tantoro; Pramana, Tri Yuli; Sugiarto, Sugiarto
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 12, NUMBER 3, December 2011
Publisher : The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy

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Abstract

Background: Non-alcoholic fatty liver disease (NAFLD) is a liver disorder commonly found in the majority of patients with metabolic risk factors, such as obesity and type 2 diabetes. Apolipoprotein B (apoB) is the moiety of low density lipoprotein (LDL) and clinical interest that provides a relative accurate estimation of circulating LDL particle. The aim of this study was to know the relationship between apoB level and occurrence of fatty liver in type 2 diabetes mellitus (DM) with metabolic syndrome. Method: A cross sectional study was conducted in patients suffered from type 2 DM with metabolic syndrome at Internal Medicine Outpatient Clinic in Moewardi Hospital Surakarta between April and May 2011. Thirty two patients with type 2 DM and metabolic syndrome were enrolled to this study and categorized into two groups; consisting of 16 patients with fatty liver and 16 patients without fatty liver. Student t-test was used in the analysis of this study. Results: Of 32 patients who fulfilled this study criteria, patients type 2 diabetes mellitus and metabolic syndrome with non-alcoholic fatty liver diseases (NAFLD) had higher apoB level than patients type 2 diabetes mellitus and metabolic syndrome without NAFLD (p = 0.013). Conclusion: NAFLD group had significantly higher apoB level than without NAFLD group in type 2 DM with metabolic syndrome patients. Keywords: apolipoprotein B, non-alcoholic fatty liver disease, type 2 DM, metabolic syndrome
Co-Authors . Lulusi, . A. As’ad Sonief Achmad Wibolo Adhy Ariyanto Adi Prayitno Adi Yusuf Setiawan, Adi Yusuf Aena Berlian Afrizal Afrizal Akmal Hidayat Angraini, Renni Anies Setiowati, Anies Anindita, Rahma Anindito Purnowidodo Apriandy, Fadhlullah Arbain Arbain, Arbain Ari Probandari Ari Rianto ARI WAHYUDI Ariansyah, Dedek Arinto Hadi, Arinto Arthur Yanny Leiwakabessy Asmaniyah Mardiyani, Siti Atmoko, Warigit Dri Augustinus Setiawan aviria ermamilia, aviria Azka, Cut Nawalul Bambang Purwanto Banun Rohimah, Banun Basin, Defry Berliana, Novi Bramaseto Rosie Pamungkas, Bramaseto Rosie Budh?ono, Fongnawati Budi Nugroho Budiyanti Wiboworini Budiyanto, Ricky Teguh Cahya, Dini Caisarina, Irin Chandradewana Boer Cut Mutiawati Danu Ariono Denny Widhiyanuriyawan Diah Suwarti Widyastuti, Diah Suwarti Didik Wahjudi Diffah Hanim Dinda, Raina Permitalia Djarot B Darmadi Djoko Sutikno Djumali Mardji Dono Indarto Dora, sylvia Terra Dwi Susilo Edy Victor Haryanto Sianturi, Edy Victor Haryanto Elbi Wiseno Entianopa, Entianopa Erwin Sulistyo Eti Poncorini Pamungkasari Fadli Fadli Fadli, Mohammad Faruq Syah Permana Putra Femiana Gapsari Fitrika Mita Suryani Gan Shu San Gilang Prasidya Jati Prasidya Jati, Gilang Prasidya Jati Gunandini, Dwi Jayanti Hadi, Upik Kesumawati Hakim, Lukman Hari Wujoso Harjono Harjono Harry Soesanto Hasnawati Hasnawati Henny Setyo Lestari, Henny Setyo Herdianti Herdianti, Herdianti Heri Sutarto Herlina, Intan Hikmi, Akbar Idris, Elfiwardah Ika Amalia Kartika Indriasari, Ika Iqbal Iqbal Islah Islah, Islah Isti Hidayah Istirochah Pujiwati, Istirochah Ita Rahmawati, Ita J. Darmawan Jalil, Erlinawati Jamasri Jamasri K. Wijayanti Karlina, Iin Khairani, Cut Khairul Khairul, Khairul Kido, Muhammad Ikram Komara, Liris Lis Krisna Harimurti, Krisna Kunarti, Eny Kurniasari, Febrina Dian Kurniawan, Rizal Mahdi Lisa Agustriyana Ludia Mersi, Ludia Lukman Hakim Lulusi Lulusi M Waziz Wildan, M Waziz M. TAUFIQ NOOR ROKHMAN Marfu'ah, Nuun Marisdaya, Rara Marwan Marwan Masduki Masduki Maulana, M. Aris Mega Nur Sasongko Merfazi, Muhammad Miyasto Miyasto Mudiantono Mudiantono Muhammad Isya Muhammad Nur Mulastin Mulastin, Mulastin Muntazar, Muntazar Musharyanti, Lisa nanang muhibuddin, nanang Novriza, Ferdiansyah Nugroho Bagus Nurhidayat, Taufik Nurhkolis Hamidi Nuun Marfuah Ofansha, Riza Permatasari, Rani Putri Pitriyani Pitriyani Pramanda, Heru Putri Balqis, Putri Rahmani, Dhuyufur randy, riki Ratna Herawati Renni Anggraini Reyhan, Mohammad Rezzy Eko Caraka Rika Rosnelly, Rika Rini Astuti Risya Cilmiaty, Risya Riyana, Raihan Icthiar RUBEN DHARMAWAN Rudy Soenoko Ruhdi Faisal rumiati, rumiati Safwan Safwan, Safwan Sahri Sahri Saiful Anwar Saiful Saiful Saleh, Sofyan M Samsul Hadi Sari, Putu Tantri K. Sari, Risda Satrya, Hendra Septiani, Baiq Dewi Sukma Septiani, Shelomita Elisabeth Setya Rahayu Sigit, Singgih Harsoyo SISWANTO SISWANTO SITI MUSLIKAH Slamet Wahyudi Soegiyanto Soegiyanto, Soegiyanto Sofyan M. Saleh Sofyan M. Saleh Soviana, Susi Sri Sundari Sri Yuliani Sudjito Soeparman Surya, Khalida Susi Soviana Suswati, Dewi Syahbuddin Syahbuddin Syara, Aprilia Taman Ginting, Taman Tantoro Harmono Taufik Taufik Tejo Nugroho Tjuk Oerbandono Tonang Dwi Ardyanto, Tonang Dwi Tri Agustina, Tri Tri Yuli Pramana Ulya, Lulu Fathnatul Ummiani Hatta Upik Kesumawati Hadi viki widiantoro, viki Wardani, Dyah Ayu Kusuma Wardati, Wardati Wardi Wardi Wawan Wawan Widhiyastuti, Endang Winata, Felix Andhy Wisudanto Wisudanto, Wisudanto Wrisnijati, Dita Wrisnijati, Dita Wuni, Cici yenni, melda Yenni, Melda yenni, melda Yoestini Yoestini Yudhi Andrian, Yudhi Yudhi Lastiasih Yudi Suryawan Yunus Yunus Zianul Furqan