Mary Soen
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ANTIINFLAMMATORY EFFECT OF DANDELION INTO ATOPIC DERMATITIS MODELS USING MICE Jasaputra, Diana Krisanti; Liana, Laella K.; Sujatno, Muchtan; Soen, Mary
Jurnal Medika Planta Vol 1, No 1 (2010)
Publisher : Jurnal Medika Planta

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Abstract

Introduction: Atopic dermatitis is an inflammation of the skin based on hypersensitivity type I reaction. Medication for atopic dermatiis can be done in conventional or inconventional ways and dandelion (Taraxacum officinale Weber et Wiggers) is one of them. Objective: to determine antiinflammatory effect of dandelion’s aqueous and ethanol extract in reducing the inflammation area and the number of inflammatory cells on mice’s skin tissue with atopic dermatitis induced by ovalbumin. Methods: The characteristic of this research was prospective experimental laboratory, using mice, injected with 0.2 ml ovalbumin 10% intracutaneously, on the first, seventh, and twenty-first days. The mice were given dandelion’s aqueous and ethanol extract with dose 1: 0.0078g/ mice 20g; dose 2: 0.0195g/ mice 20g;  dose 3: 0.039g/ mice 20g; dose 4: 0.078 g/ mice 20g perorally. Results: The results show that dandelion’s aqueous extract with dose 4 (6.640mm2) and ethanol extract with dose 2 (5.013mm2)  were the most effective doses in reducing the inflammation area (p<0,05). The summary result of the number of inflammation cells shows statistically significant on giving the dandelion’s ethanol extract dose 1 and 2 compared with the positive control (p<0,05). The effectivity of ethanol extract equal to the aqueous extract in reducing the inflammation coverage area and the number of inflammation cells. Conclusion: both dandelion’s aqueous and ethanol extract are effective in reducing the inflammation coverage area, ethanol extract effective to reduce the number of inflammation cells. Both dandelion’s aqueous and ethanol extract are equally effective.
Monitoring dan Evaluasi Pelaksanaan Strategi Directly Observed Treatment Shortcourse sebagai Upaya Penanggulangan Tuberculosis di Puskesmas yang Berada dalam Lingkup Pembinaan Dinas Kesehatan Kabupaten Subang Kasim, Felix; Soen, Mary; Hendranata, Katrin Fitria
Jurnal Kebijakan Kesehatan Indonesia Vol 1, No 3 (2012)
Publisher : Center for Health Policy and Management

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (458.135 KB) | DOI: 10.22146/jkki.v1i3.36019

Abstract

Background: The implementation of the DOTS strategy in health centers aims to, among others, reduce morbidity rates and break the chain of transmission. Indonesia ranks third on the incidence of TB cases. In general, this research aimed to investigate the effort implementation, barriers, benefits and expectations in implementing the DOTS program in 40 health centers within the work area of Subang District Health Office. Methods: This was a qualitative study. Data collection technique was in-depth interviews to the head of health centers and P2TB officers, the DOTS corner participation observation and Focus Group Discussion of TB officers. The research instruments were recorder and camera. The number of population was 40 health centers taken with cluster random sampling technique and the number of samples was 10 health centers, represented by 10 heads of the health centers and 10 P2TB officers. Results: This study found out things such as efforts, barriers, benefits and expectations of the implementation of the DOTS strategy in the health centers of Subang District. The efforts made in 10 health centers were good enough, with some constraints such as lack of laboratory infrastructure, lack of human resources, intersectional collaboration, medication compliance, and the role of PMO personnel, economic factors and poor public education, drug distribution delays, difficulties in recording and reporting of patient transfer. Therefore, improvements should be done in cross-sectoral communication, completeness of lab infrastructure, empowerment of each village cadre for education and networking. Conclusion: In 10 health centers (Pagaden, Gunung sembung, Kalijati, Binong, Purwadadi, Palasari, Cisalak, Kasomalang, Sagalaherang, and Serang Panjang) DOTS program had been done in an effort to overcome tuberculosis in accordance with the 5 elements of DOTS. Latar belakang: Pelaksanaan strategi DOTS di puskesmas salah satunya bertujuan mengurangi angka kesakitan dan memutus rantai penularan. Indonesia menduduki peringkat ketiga insidensi kasus TB. Secara umum penelitian ini bertujuan adalah untuk mengetahui upaya pelaksanaan, kendala-kendala, manfaat dan harapan dalam menjalankan program DOTS di 40 Puskesmas yang berada dalam lingkup pembinaan Dinas Kesehatan Kabupaten Subang. Metode: menggunakan metode kualitatif, teknik pengumpulan data wawancara mendalam Kepala Puskesmas dan Petugas P2TB Puskesmas, Observasi Partisipasi Pojok DOTS, serta Focus Group Discussion kader TB, instrumen penelitian berupa alat perekam dan kamera, jumlah populasi 40 Puskesmas, teknik pengambilan sampel Cluster Random Sampling, jumlah sampel 10 Puskesmas, diwakili 10 kepala Puskesmas, 10 petugas P2TB. Hasil: penelitian, didapatkan upaya, kendala, manfaat dan harapan pelaksanaan Strategi DOTS di Puskesmas Kabupaten Subang. Kesimpulan: upaya yang dilakukan di 10 Puskesmas sudah cukup, dengan beberapa kendala seperti ketiadaan sarana prasarana laboratorium, kurangnya SDM, kerja sama lintas sektoral, kepatuhan minum obat, peran dan tenaga PMO, faktor ekonomi dan rendahnya pendidikan masyarakat, keterlambatan pendistribusian obat, sulitnya pencatatan dan pelaporan pasien pindah dan pindahan. Sebaiknya dilakukan komunikasi lintas sektoral, mengusahakan kelengkapan sarana-prasarana lab, pemberdayaan kader tiap desa untuk penyuluhan dan penjaringan.