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Effect of isoflavones genistein and daidzein tokbi extract (Pueraria lobata) Kangean strain against the number of osteoblasts and osteoclasts Rattus Wistar Novergicus hipoestrogenik Wiyasa, I. W.A.; Norahmawati, E.; Soehartono, Soehartono
Indonesian Journal of Obstetrics and Gynecology Vol. 32 No. 3 Juli 2008
Publisher : Indonesian Journal of Obstetrics and Gynecology

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Objective: To determine the effect of isoflavone genistein and daidzein of tokbi (Pueraria Lobata) of Kangean strain’s extract to the number of hipoestrogenic Rattus Novergicus’s osteoblast and osteoclast.Material and methods: The design of this study was experimental. The research started with the preliminary study to determined isoflavone genistein and daidzein (IGD) concentration in tokbi extract and to make hipoestrogenic rats model. This study used 28 female rats; 6 rats were normal rats as first group and 22 rats were hypoestrogenic rats as 2nd, 3rd, 4th, and 5th groups. All of the 22 hypoestrogenic rats were divided into 4 groups. They were 6 rats of ovariectomized (OVX) group, 5 rats of OVX by giving tokbi extract containing isoflavone of 15 mg/kg BW/day (OVX + IGD), 5 rats of OVX + IGD of 30 mg/kg BW/day, and 6 rats of OVX + IGD of 60 mg/kg BW/day. All groups were treated for 21 days. The numbers of osteoblast (OBL) and osteoclast (OCL) were used as parameters.Result: One ml Pueraria lobata extract contained 282.53 ppm of IGD with the composition of 231.11 ppm of daidzein and 51.41 ppm of genistein. A significant difference was found in the amount of OBL and OCL between OVX and OVX + IGD groups at all doses (p < 0.05 of each). The highest number of OBL and the lowest number of OCL were found in OVX + IGD groups of 30 mg/kg BW/day.Conclusion: IGD of Pueraria lobata extract could increase OBL and decrease OCL at all doses, particularly the 30 mg/kg BW/day dose of IGD.Keywords: isoflavone, genistein, daidzein, tokbi, osteoblast, osteoclast, hypoestrogen.
KEDUDUKAN KEPALA DESA DALAM UPAYA PENYELESAIAN SENGKETA DALAM MASYARAKAT Soehartono, Soehartono
YUSTISIA Vol 65 (2004)
Publisher : YUSTISIA

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Peoples, especially who liveat the village stillacknowledge the existence ofthe vilagejudge. Suchthing can be seen most of the dispute happened between the people andthe otherare brought to the village chief to be settled. The village people prefer to settle their dispute by non litigation manner. Non litigation option is chosen as considered more economical and more democratic, compromise, still keep the harmonization of the family relationship. By such method the exist relationship can be kept.
EKSISTENSI ASAS-ASAS UMUM PEMERINTAHAN YANG BAIK SEBAGAI DASAR PENGUJIAN KEABSAHAN KEPUTUSAN TATA USAHA NEGARA Dl PERADILAN TATA USAHA NEGARA Soehartono, Soehartono
YUSTISIA Vol 83 (2011)
Publisher : YUSTISIA

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The basis of legality authentication on state administrative decision (berschikking) is that the state administrative decision is charged as in contradictory with the legislationprevailingand the general principlesof good governance. Such the provision is governed in Article 53 clause (2) a,b, Act Number 9 of 2004 about PTUN, as the firstamendment to the Act Number 5 of 1986 about PTUN. The existence of good governance general principles in the Act Number 5 of 1986 has not been confirmed as legal norm, but in the Act Number 9 of 2004, the general principles of good governance (AAUPB) have been confirmed in fonnaljuridicalway as the legal norm. Inthe presence ofsuch the confirmation, various opinions raise, on the one hand, the presence ofAAUPB confirmation restricts thejudges movement, so that the existence of AAUPBremains to be ethics and is not necessary to be includedinto the Act. AAUPBis bettergrowing and developing in non-written legal norm as code of ethics. On the otherhand, some people argues that AUPB continued in formaljuridical way as a legal norm is not a problem, because thejudge in the society change and development is required to be more active, creative, future oriented and not handcuffedby normative rules as the legal positivism tenet prioritizing more the proceduraljustice. Thejudge may not be bound by the written convention only but should also explore the legal values and sense ofjustice living within the society as mandatedby thejurisdictionallaw. TheJudge interprets and constructslaw to produces a verdict emphasizing on the justice the society expects.
SOSIALISASI PEMBAHARUAN PEMIKIRAN HUKUM ISLAM DI INDONESIA Soehartono, Soehartono
YUSTISIA Vol 48 (1999)
Publisher : YUSTISIA

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Dalam beberapa dekade belakangan ini pembicaraan tentang reaktualisasi ajaran Islam atau lebih khusus reaktualisasi hukum Islam selalu mendapat tanggapan yang menarik di dalam masyarakat, khususnya dari umat Islam. Hal ini disebabkan, umat Islam di dunia, di satu pihak, memerlukan keberadaan hukum Islam sebagai hukum agama yang dapat mengayomi kehidupan di dunia dan di akherat mereka.
ANALISIS PUTUSAN MAHKAMAH AGUNG NOMOR 51/K/AG/l999 DALAM PERKARA AHLIWARIS BEDA AGAMA Soehartono, Soehartono
YUSTISIA Vol 63 (2003)
Publisher : YUSTISIA

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According to Supreme Court decision number 51/AG/1999, soYogyakarta moslem court and high court more inaccordance with the.values existing within society. Islamic law compilation which used asbasic law and become a law guidance for moslem court is the core ofmatterial Islamic law that being united from many fiqih book. Thecompilation being used for islamic people is purpused to give lawprotection, law order, justice and law certainty, moreover to createsociety welfare. Its means that Islamic law compilation as lawguidance for moslem court can not be abandoned as its existencyhavebeenaccepted bymoslem society specificaly.
MENGEMBANGKAN PEMIKIRAN HAKIM DALAM MENYELESAIKAN SENGKETA Soehartono, Soehartono
YUSTISIA Vol 88 (2014)
Publisher : YUSTISIA

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penelitian ini ingin mengkaji  tentang peran hakim, khusunya dalam menjatuhkan putusan terhadap sengketa yang diajukan kepada. Apakah dalam menyelesaikan sengketa hanya berdasarkan pada undang-undang (produk legislatif) atau juga berdasarkan pada hukum yang tidak tertulis yang hidup dalam masyarakat. penelitian ini bersifat sosiologis atau penelitian hukum yang bersifat empiris. Data yang dipergunakan adalah data primer, juga data sekunder sebagai pendukung. pengumpulan data dilakukan dengan metode wawancara, juga dengan studi kepustakaan. Analisis data bersifat kualitatif. Berdasarkan hasil penelitian dan analisis data, dapat disimpulkan bahwa hakim dalam memutus dan menyelesaikan sengketa tidak selamanya hanya berdasarkan pada hukum tertulis atau undang-undang sebagai produk legislatif. Dalam memutus dan menyelesaikan sengketa hakim juga mendasarkan pada hukum tidak tertulis (memperhatikan kearifan lokal). hakim tidak hanya mendasarkan pada logika dan ketentuan undang-undang, namun sebagai penegak hukum dan keadilan, hakim dalam memutus dan menyelesaikan sengketa juga mendasarkan pada empaty dan juga perasaan. Tidak hanya menggunakan kecerdasan IQ, tetapi juga EQ dan SQ.
EFFECT OF CONSUMING GREEN BEAN (PHASEOLUS RADIATUS) JUICE ON MATERNAL BLOOD PROFILE DURING PREGNANCY Anastasia S, Stefani; Soehartono, Soehartono; Ngadiyono, Ngadiyono; Muchlis, Muchlis; Dyah, Dyah
Belitung Nursing Journal Vol 3, No 5 (2017): September-October 2017
Publisher : Belitung Nursing Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (250.272 KB) | DOI: 10.33546/bnj.197

Abstract

Background: Most of anemia in pregnancy is caused by iron deficiency. Thus, giving iron tablets is an effort to deal with anemia. A green bean  (Phaseolus Radiatus) juice is considered helping the absorption of iron effectively.Objective: To analyze the effect of green bean (Phaseolus Radiatus) juice on changes in blood profile levels in pregnant women with anemia who received Fe tablet supplementation.Methods: This was a quasy-experimental study with pretest posttest with control group design conducted from November 2016 to January 2017 in the working area of the Community Health Center of Kedungmundu Semarang.Consecutive sampling was used in this study to select 40 samples based on the hypothesis formula of two independents. There were 20 samples assigned in each group. Data were analyzed using paired t-test and Independent t-test.Results: The results of this study showed that there were significant increases in hemoglobin, hematocrit, and erythrocytes (p = 0.000) after given green bean (Phaseolus Radiatus) juice.Conclusion: There was a significant effect of green bean (Phaseolus Radiatus) juice in increasing the levels of hemoglobin, hematocrit, and erythrocytes. It is expected that this green bean juice can be used as an alternative treatment to deal with anemia in pregnant women.
Pengaruh isoflavone genistein dan daidzein ekstrak tokbi (Pueraria lobata) strain Kangean terhadap jumlah osteoblas dan osteoklas Rattus Novergicus Wistar hipoestrogenik WIYASA, I. W.A.; NORAHMAWATI, E.; SOEHARTONO, SOEHARTONO
Indonesian Journal of Obstetrics and Gynecology Volume. 32, No. 3, July 2008
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Membuktikan pengaruh pemberian isoflavone genistein dan daidzein (IGD) ekstrak tokbi (Pueraria lobata) strain Kangean terhadap jumlah osteoblas (OBL) dan osteoklas (OKL) Rattus novergicus Wistar hipoestrogen. Bahan dan cara kerja: Penelitian eksperimental ini diawali dengan studi pendahuluan untuk menentukan konsentrasi IGD dalam ekstrak tokbi dan membuat model tikus hipoestrogen. Menggunakan 28 tikus betina, 6 tikus normal sebagai kelompok pertama dan 22 tikus hipoestrogen dibagi menjadi 4 kelompok sebagai kelompok 2, 3, 4, dan 5. Kelompok tikus hipoestrogen terdiri dari 6 tikus ovariektomi (OVX), 5 tikus OVX diberi IGD (OVX + IGD) 15 mg/kg BB/hari, 5 tikus OVX + IGD 30 mg/kg BB/hari, dan 6 tikus (OVX + IGD) 60 mg/kg BB/hari. Semua kelompok diterapi selama 21 hari. Parameter yang digunakan adalah jumlah OBL dan OKL. Hasil: Satu ml ekstrak Pueraria lobata mengandung 282,53 ppm IGD dengan komposisi 231,11 ppm daidzein dan 51,41 ppm genistein. Didapatkan perbedaan bermakna jumlah OBL dan OKL antara kelompok OVX dan OVX + IGD pada semua dosis (p < 0,05). Jumlah OBL terbesar dan OKL terkecil terdapat pada kelompok OVX + IGD 30 mg/ kg BB/hari. Kesimpulan: IGD dari ekstrak Pueraria lobata dapat meningkatkan OBL dan menurunkan OKL pada semua dosis, terutama dosis 30 mg/ kg BB/hari. [Maj Obstet Ginekol Indones 2008; 32-3: 148-52] Kata kunci: isoflavone, genistein, daidzein, tokbi, osteoblas, osteoklas, hipoestrogen.
KEBIJAKAN PENDIDIKAN DI TINJAU DARI SEGI HUKUM KEBIJAKAN PUBLIK Hastuti, Tri Puji; Soehartono, Soehartono
Jurnal Jurisprudence Vol 8, No 1 (2018): Vol 8, No 1, 2018
Publisher : Muhammadiyah University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jurisprudence.v8i1.6293

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Nation education system is a system which integraded from all unit and education activities which related each other to reach national education purpose. Because of Indonesia education renewal demand, education wisdom has been through many changes. In this matter, education wisdom is viewed from public wisdom which is made by country, executive, legislative, judicative.Making decision about national education system is related with public wisdom. Public wisdom is new science because historically it appears in the midlle 1960 as a discipline in public administration and politic.The important matter which become attention is education wisdom that park from public wisdom. Research which is done by researcher is diagnostic research. This research uses doctrinal (normative) method and has purposeto know the base of public wisdom in education and analyze public wisdom in education
DESAIN KONSTRUKSI MEJA BETON PENYANGGA POWER TRANSFORMER 80 MVA PT KDL CILEGON Amariansah, Widayat; Soehartono, Soehartono
Neo Teknika Vol 2, No 1 (2016): Jurnal Neo Teknika Vol. 2 No.1, Juni 2016
Publisher : Universitas Pandanaran

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PT Krakatau Daya Listrik (KDL) merupakan anak perusahaan PT Krakatau Steel (Persero) Tbk yang berfungsi membangkitkan energi listrik dari PLTU 5x80 MW milik sendiri dan menyalurkannya melalui jaringan transmisi 150 kV dan distribusi 30 kV, 20 kV, 6 kV, 400 V ke seluruh industri, kantor dan perumahan karyawan di lingkungan Krakatau Industrial Estate Cilegon-Banten. Untuk meningkatkan keandalan dan jumlah pasokan listriknya, PT KDL membangun Main Transfer Station unit IV (MTS IV) yang berfungsi sebagai gardu induk yang menerima, mengatur dan mendistribusikan suplai listrik dari PLTU ke masing-masing pabrik. MTS IV terdiri dari bangunan gedung kontrol 30 kV dan bangunan penyangga power transformer 3x80 MVA yang berimpit di dekatnya. Kedua bangunan ini dipisahkan dengan sistem dilatasi. Struktur beton penyangga power transformer 3x80 MVA ini berbentuk meja yang mempunyai 3 ruang untuk setiap transformer. Setiap ruang terdiri dari 1 lantai dasar dan 2 lantai basement yang dirancang untuk menahan berat setiap transformer sebesar 115 ton.Kata kunci : Beton, bangunan penyangga, power transformer