Mulya Nusa Amrulah Ritonga
Medical Faculty of Padjadjaran University/ Dr. Hasan Sadikin Hospital Bandung

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Knowledge and attitude of pregnant woman toward umbilical-cord-blood collection Djuwantono, Tono; Ritonga, Mulya Nusa Amrulah; Wirakusumah, Firman Fuad; Effendi, Jusuf Sulaeman; Halim, Danny; Faried, Ahmad
Indonesian Journal of Obstetrics and Gynecology Vol. 34. No 2. April 2010
Publisher : Indonesian Journal of Obstetrics and Gynecology

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Abstract

Objective: Stem cell technology from umbilical cord blood (UCB) has developed fast as health services. UCB could be used in many kinds of disease. Private UCB bank has been operated in many places all over Indonesia. There’s a need for research to evaluate the knowledge and attitude of pregnant woman towards the act of collecting UCB.Method: This is a cross-sectional study base on question-naire given to 163 pregnant women in three private hospitals in the Bandung City from September - November 2009. The result was analyzed with Rank-spearman correlation and Kruskal-Wallis chisquare.Result: Most respondent were 20 - 29 years old pregnant women (54.6%), with educational level of strata-1 (S-1) (41.1%), with monthly income within 5 - 10 million rupiah (35.6%). This is the second pregnancy or more (42.9%), with gestational age less than 24 weeks (61.3%) and variative obstetric history (59.5%). The average level of knowledge was poor and attitude scale was uncertain (3.4). There is a significant correlation between age (p = 0.008%; CI 95%), level of education (p = 0.0001; CI 95%) and knowledge. There is a significant correlation between gestational age and attitude (p = 0.003; CI 95%). Respondent’s level of knowledge also has a significant correlation with attitude (τs = 0.421; p = 0.0001; CI 95%).Conclusion: This study described the respondent’s poor knowledge will influence their attitudes toward UCB collection, so it is necessary for disseminating more information on UCB as an effort to get better research result on UCB.[Indones J Obstet Gynecol 2010; 34-2: 97-100]Keywords: knowledge level, attitudes, collecting UCB, pregnant woman, the Bandung city Tujuan: Tujuan: Teknologi sel punca yang berasal dari darah tali pusat (DTP) saat ini berkembang dengan pesat untuk pelayanan kesehatan. DTP ini dapat dipergunakan pada berbagai macam penyakit. Beberapa cabang bank DTP swasta telah beroperasi di Indonesia. Sehingga perlu dilakukan penelitian tingkat pengetahuan dan sikap ibu hamil terhadap pengumpulan DTP. Metode: Dilakukan penelitian survey cross-sectional pada 163 orang ibu hamil di tiga rumah sakit swasta Kotamadya Bandung sejak September - November 2009. Kuisioner berupa kuesioner tertutup.Hasil yang di dapat dianalisis dengan menggunakan uji korelasi Rank-Spearman dan uji chi-kuadrat Kruskal-Wallis. Hasil: Karakteristik terbesar responden berusia 20 - 29 tahun (54,6%), berpendidikan S-1 (41,1%), pendapatan perbulan 5 sampai 10 juta rupiah (35,6%). Kehamilan saat ini adalah kehamilan yang ke-2 atau lebih (42,9%), usia kehamilan kurang dari 24minggu (61,3%) dan riwayat obstetri yang bervariasi (59,5%). Rerata tingkat pengetahuan kurang (50,97%) dan skala sikap raguragu (3,4). Didapatkan hubungan bermakna antara usia (p = 0,008%; CI 95%) dan tingkat pendidikan terhadap tingkat pengetahuan (p = 0,0001; CI 95%). Terdapat hubungan bermakna antara usia gestasi dengan sikap responden (p = 0,003; CI 95%). Tingkat pengetahuan responden juga bermakna secara statistikterhadap sikap responden (τs = 0,42; p = 0,000; CI 95%).Kesimpulan: Penelitian ini menggambarkan tingkat pengetahuan responden yang rendah akan mempengaruhi sikap terhadap pengumpulan DTP, sehingga dibutuhkan penyebaran informasi yang lebih baik lagi mengingat manfaat yang didapat melalui penelitian DTP.[Maj Obstet Ginekol Indones 2010; 34-2: 97-100]Kata kunci: tingkat pengetahuan, sikap, pengumpulan darah tali pusat, ibu hamil, Kotamadya Bandung
Embryo Quality: The Most Critical Factor for Pregnancy Rates after day-2, day-3, and day-5 of Embryo Transfer Djuwantono, Tono; Permadi, Wiryawan; Harlianto, Harris; Ritonga, Mulya Nusa Amrulah; Halim, Danny; Achmad, Tri Hanggono; Faried, Ahmad
Indonesian Journal of Obstetrics and Gynecology Vol. 34. No. 4. October 2010
Publisher : Indonesian Journal of Obstetrics and Gynecology

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Abstract

Objective: To determine the most critical factor on day-2, day-3, and day-5 of embryo transfer in correlation with pregnancy rates.Method: This research is a retrospective study in Aster Fertility Clinic, IVF program- Dr. Hasan Sadikin Hospital, Bandung, Indonesia. One hundred ninety five women enrolled in an IVF program conducted from March 2006 through November 2009 at the Aster Fertility Clinic. Effect of embryo-transfer day and any other factors (including quality of embryo, oocyte quantity, difficulty of embryo transfer technique, and blood or mucus contamination on the catheter) on pregnancy rate in IVF.Results: The mean age of the pregnant group was 34.65 (SD = 3.91), and the mean of the infertility period was 7.25 years (SD = 3.54). There were no siginificant differences in pregnancy rates in the day-2, day-3, and day-5 groups. The most critical factor influencing pregnancy was the total score for the quality of embryos [p = 0.001; OR (CI 95%) = 1.94 (0.91 - 4.08)]. Otherwise, the day of embryo transfer, oocyte quantity, and difficulties in embryo transfer did not affect the pregnancy rate (p > 0.05).Conclusion: Our study suggests that the total score for the quality of the embryos was the most critical factor for the success rate of pregnancy rather than the day of embryo transfer, oocyte quantity, difficulty of embryo transfer technique, or contamination of blood and mucus on the catheter.[Indones J Obstet Gynecol 2010; 34-4: 175-9]Keywords: day of embryo transfer, in vitro fertilization, quality of embryo total score, oocytes quantity, catheter contaminationTujuan: Untuk menentukan faktor yang terpenting pada keberhasilan kehamilan setelah transfer embrio hari ke-2, ke-3 dan ke-5.Metode: Penelitian ini adalah studi retrospektif di klinik Fertilitas Aster, Program IVF- Rumah Sakit Dr. Hasan Sadikin, Bandung, Indonesia. Penelitian ini melibatkan seratus sembilan puluh lima perempuan yang mengikuti program IVF sejak Maret 2006 hingga Nopember 2009. Efek dari waktu (hari) transfer embrio dan faktorfaktor lainnya (termasuk kualitas embrio, jumlah oosit, kesulitan dalam teknik transfer embrio, dan kontaminasi darah atau mukus dalam kateter) terhadap angka keberhasilan kehamilan pada IVF.Hasil: Rata-rata usia perempuan hamil pada penelitian ini 34,65 (SD = 3,91), dan rata-rata periode infertilitas 7,25 (SD = 3,54). Tidak terdapat perbedaan bermakna pada angka kebehasilan kehamilan setelah transfer embrio baik pada hari ke-2, -3 dan -5. Faktor terpenting yang mempengaruhi keberhasilan kehamilan adalah skor total dari kualitas embrio [p = 0,001; OR (CI 95%) = 1,94 (0,91 - 4,08)]. Dilain fihak, waktu transfer embrio, jumlah oosit, kesulitan dalam teknik transfer embrio tidak mempengaruhi kebehasilan kehamilan (p > 0,05).Kesimpulan: Hasil studi kami menunjukkan bahwa faktor terpenting yang mempengaruhi keberhasilan kehamilan adalah skor total dari kualitas embrio dibandingkan dengan waktu transfer embrio, jumlah oosit, kesulitan dalam teknik transfer embrio, atau kontaminasi darah dan mukus dalam kateter.[Maj Obstet Ginekol Indones 2010; 34-4: 175-9]Kata kunci: hari setelah transfer embrio, fertilisasi in vitro, skor total dari kualitas embrio, jumlah oosit, kontaminasi kateter