Arsita Eka Rini
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FAKTOR RISIKO NEONATUS BERGOLONGAN DARAH A ATAU B DARI IBU BERGOLONGAN DARAH O TERHADAP KEJADIAN HIPERBILIRUBINEMIA Khusna, Nailul; Mexitalia, Maria; Rini, Arsita Eka; Sulistyawati, Endang
MEDIA MEDIKA MUDA Vol 2, No 1 (2013): MEDIA MEDIKA MUDA
Publisher : MEDIA MEDIKA MUDA

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Abstract

Latar Belakang:Hiperbilirubinemia merupakan kasus yang banyak terjadi, hal ini menjadi masalah di negara maju dan negara berkembang.  Ketidaksesuaian golongan darah merupakan penyebab terbanyak penyakit hemolitik neonatal yang sulit untuk dikenali manifestasinya.Tujuan: Membuktikanneonatus bergolongan darah A atau B dari ibu bergolongan darah O merupakan faktor risiko hiperbilirubinemia neonatus.Metode: Penelitian observasional analitik dengan rancangan cross sectional. Subyek adalah neonatus yang bergolongan darah A, B, O dari ibu yang bergolongan darah O. Data berupa data sekunder berupa catatan medik di Rumah Sakit Ibu dan Anak Hermina Pandanaran Semarang selama periode Januari 2011 – Desember 2012. Data dianalisis dengan menggunakan uji Chi-Square test dengan nilai p< 0,05.Hasil: Dari 244 neonatus terdapat 19 neonatus (7,8%) yang mengalami hiperbilirubinemia. , terdiri dari 5 (10, 9%) neonatus bergolongan darah A, 7 (14,3 %) neonatus bergolongan darah B, dan 7 (4,7%) neonatus bergolongan darah O. Neonatus  bergolongan darah A bukan merupakan faktor risiko hiperbilirubinemia (p= 0,128 ; OR= 2,47 ; CI= 0,75-8,21). Neonatus bergolongan darah B mempunyai faktor risiko sebesar 3,4x lebih besar dari pada neonatus bergolongan darah O (p = 0,023 ; OR= 3,38 ; CI= 1,12-10,19). Selain itu, didapatkan perbedaan rerata kadar bilirubin yang bermakna terdapat pada kelompok neonatus golongan darah A - O dan B- O (p = 0,044 vs 0,004).Kesimpulan: Neonatus yang bergolongan darah B dari ibu yang bergolongan darah O memiliki rerata kadar bilirubin dan insiden hiperbilirubinemia lebih tinggi dari pada neonatus golongan darah A dan O, dan merupakan faktor risiko terhadap kejadian hiperbilirubinemia pada neonatus.
FAKTOR RISIKO PENYAKIT MEMBRAN HIALIN PADA BAYI BERAT LAHIR RENDAH Dwiristyan, Fardiansyah; Sarosa, Gatot Irawan; Rini, Arsita Eka
JURNAL KEDOKTERAN DIPONEGORO Vol 4, No 4 (2015): MEDIA MEDIKA MUDA
Publisher : Jurusan Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro

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Background. The morbidity and mortality of low birth weight babies (LBW) are still high caused by respiratory disorder, hyaline membrane disease (HMD). Early diagnosis and detection of risk factors are important to prevent HMD in LBW babies.Aim. To determine risk of premature rupture of membrane, gestational age, preeclampsia, birth weight, and without giving antenatal steroid (ANS) as the incidence of HMD in LBW babies.Methods. This study was a retrospective observasional study with case control design conducted in Dr. Kariadi Hospital using medical records since January 2012-December 2014 with LBW babies. Subjects were choosen with purposive sampling divided into 2 groups, case group (44 LBW babies with HMD) and control group (44 LBW babies without HMD) diagnosed with HMD by chest x-ray. This study used bivariate analysis with Chi-square test and multivariate analysis with logistic regression analysis.Results. In bivariat analysis showed risk factors of HMD’s incidence in LBW babies were gestational age (p=0,015; OR= 4,19; 95% CI= 1,24-14,13) and birth weight (p=0,019; OR=3,12; 95% CI= 1,18-8,25). In multivariate analysis, birth weight (p=0,019; OR= 3,36; 95% CI= 1,22-9,23) was risk factors.Conclusion. Birth weight (very low birth weight) factor was risk factors of HMD’s incidence in LBW babies.
FAKTOR RISIKO KEMATIAN BAYI BARU LAHIR DENGAN PENYAKIT MEMBRAN HIALIN YANG DIBERI CONTINUOUS POSITIVE AIRWAY PRESSURE (CPAP) Rahmalia, Mustika; Sarosa, Gatot Irawan; Rini, Arsita Eka
JURNAL KEDOKTERAN DIPONEGORO Vol 4, No 4 (2015): MEDIA MEDIKA MUDA
Publisher : Jurusan Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro

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Abstract

Background. Newborns with hyaline membrane disease (HMD) were still able to experience death although they were given by continuous positive airway pressure (CPAP). Early diagnosis and detection of multiple factors asosiated to these incident could be used to prevent mortality in newborns with HMD were given CPAP.Aim. To determine low birth weight (LBW), infection, premature, began CPAP> 5 hours after birth, the degree of HMD, asphyxia, not given antenatal steroids and surfactant as factors assosiated to the mortality of newborns with HMD were given CPAP.Methods. An analytical observational study with case control design was conducted in Dr. Kariadi Hospital using medical records in January 2009 - December 2014. The group of 20 cases of newborns with HMD were given CPAP and died. The control group are newborns with HMD were given CPAP and survived as much as 20 babies. Subjects taken by consequtive sampling method. HMD was based on doctors diagnosis and/or radiology. Bivariate analysis was done using Chi-square and Fisher Exact. Multivariate analysis was done using logistic regression.Results. Multivariate analysis found the factors that influence the mortality of newborns with HMD by CPAP is the severity of HMD (p=0.006;OR=4,666; 95%CI=1,568-13,888). Factors other than the severity of PMH does not become an influential factor.Conclusion. Severity factor of HMD was assosiated with mortality of newborns with HMD were given CPAP.
Faktor Risiko Air Ketuban Keruh Terhadap Kejadian Sepsis Awitan Dini pada Bayi Baru Lahir Kosim, Muhammad Sholeh; Rini, Arsita Eka; Suromo, Lisyani B
Sari Pediatri Vol 12, No 3 (2010)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp12.3.2010.135-41

Abstract

Latar belakang. Sepsis neonatorum merupakan masalah utama dan penyebab kematian terbanyak di negaraberkembang. Air ketuban keruh bercampur mekonium merupakan salah satu faktor risiko sepsis bayi barulahir dan terjadi pada sekitar 10%-20% seluruh kelahiran.Tujuan. Membuktikan air ketuban keruh merupakan faktor risiko kejadian sepsis awitan dini pada bayibaru lahir.Metode. Penelitian menggunakan desain kohort. Subjek adalah bayi dengan kriteria inklusi dan lahirdengan air ketuban keruh bercampur mekonium di RS Dr. Kariadi bulan Oktober 2009 – Maret 2010.Bayi lahir dengan air ketuban jernih sebagai kontrol. Air ketuban diambil pada hari ke-1, biakan darah,dan pemeriksaan darah tepi pada hari ke-5. Analisis statistik menggunakan chi square, Mann Whitney, danrisiko relatif (95% confidence interval).Hasil. Subjek 70 bayi lahir dengan air ketuban keruh berisiko 10x lebih tinggi mengalami sepsis (95%CI=1,3-74,0; p=0,003). Risiko relatif adanya kuman pengecatan Gram (+) di dalam air ketuban terhadapterjadinya sepsis 1,4 (95%CI=0,3-6,8;p=0,6) dan adanya kedua jenis kuman Gram (+) dan (-) 2,4 (95%CI=0,7-7,7; p=0,2). Risiko relatif bayi dengan air ketuban mengandung biakan E coli mempunyai risikokejadian sepsis 3,8 (95%CI=0,8-17,0;p=0,057) dan biakan non E coli 2,4 (95% CI=0,4-13,1; p=0,4).Faktor risiko lain adalah adanya kuman dalam biakan darah, berisiko 6,3 x lebih tinggi mengalami sepsis(95% CI=1,4-29,3; p=0,02).Kesimpulan. Air ketuban keruh merupakan faktor risiko terjadinya sepsis bayi baru lahir awitan dini. Jeniskuman pengecatan Gram dan biakan kuman dalam air ketuban bukan merupakan faktor risiko terjadinyasepsis awitan dini
Meconium-stained amniotic fluid viscosity and chest x-ray findings Rajagukguk, Ricki; Kosim, Muhammad Sholeh; Rini, Arsita Eka; Mardiana, Mardiana
Paediatrica Indonesiana Vol 52 No 6 (2012): November 2012
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (140.084 KB) | DOI: 10.14238/pi52.6.2012.336-40

Abstract

Background Approximately 8-15% of all infants are born withevidence of meconium-stained amniotic fluid (MSAF). Manyof these infants rapidly initiate a good respiratory response andare othenvise vigorous. Other infants present v.ith a variety ofrespiratory distress. Chest x-ray imaging is the main test done toevaluate respiratory distress in order to differentiate pulmonaryand extrapulmonary etiologies.Objective To determine the relationship between viscosity ofMSAF and chest x-ray imaging results.Methods This cross-sectional study was held from January to June2011, as a continuation of a previous study from August 2009 toMay 2010 at Kariadi Hospital, Semarang, Indonesia. Data wastaken from medical records of babies who were born v.ith MSAF.MSAF viscosity measurements by the investigator and laboratorytechnician were assessed by Kappa test in the previous study witha result of 0.7 4. X-ray findings were determined by the radiologiston duty at that time. Chi square and logistic regressiontests wereused for statistical analysis.Results There were 48 subjects consisting of 26 males and 22females. Chest x-ray imaging results showed normal findings in33.3% of subjects, pneumonia in 58.3% of subjects and meconiumaspiration syndrome in 8.3% of subjects. Thick viscosity MSAFwas significantly correlated to abnormal x-ray imaging (RR= 2.046;P=0.004; 95%CI 1.12 t03.72).Conclusion Thick MSAF viscosity significantly increased therisk of abnormal chest x-ray findings. [Paediatr Indones.2012;52:336-40].