Eva Rachmi
Medical Education Unit, Medical Faculty, Universitas Mulawarman

Published : 3 Documents
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Fagraea racemosa leaf extract inhibits oxidative stress-induced liver damage in Wistar rats Rachmi, Eva; Riastiti, Yudanti
Health Science Journal of Indonesia Vol 2, No 1 Apr (2011)
Publisher : Badan Penelitian dan Pengembangan Kesehatan

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Latar belakang: Kemampuan hati mengatasi stres oksidatif dapat ditingkatkan dengan konsumsi antioksidan eksogen yang berasal dari alam. Penelitian ini ditujukan untuk mempelajari kemampuan hepatoprotektif dari ekstrak metanol  daun  Fagraea racemosa, dengan menggunakan CCL4 sebagai model sumber radikal bebas. Metode: Tiga kelompok perlakuan tikus Wistar  (enam ekor per  kelompok), masing-masing diberi dosis ekstrak berturut-turut 50, 100, 200 mg/kg bb per oral, sekali perhari selama 30 hari. CCl4 diinjeksikan intraperitoneal kepada ketiga kelompok , dua kali per minggu (1,5 ml/kg bb).  Sebagai pembanding, digunakan dua kelompok kontrol, yaitu kontrol normal dan kontrol CCl4.  Pada hari ke-30, tikus dibunuh dan hati diwarnai dengan hematoksilin-eosin. Perubahan histopatologi ditentukan berdasar derajat steatosis, degenerasi hidropik, dan inflamasi. Data dianalisis dengan Anova dan uji post hoc LSD (p≤0.05) menggunakan SPSS versi 13.0 Hasil: Hasil menunjukkan perbaikan derajat degenerasi hidropik dan inflamasi (p≤0,05) pada ketiga kelompok perlakuan bila dibanding dengan kelompok kontrol CCl4. Tetapi, derajat steatosis meningkat pada kelompok perlakuan dosis  50 dan 100 mg/kg bb, dan kemudian menurun secara bermakna pada perlakuan 200 mg/kg bb. Kesimpulan : Ekstrak methanol daun Fagraea racemosa  mampu melindungi hati dari radikal bebas yang dihasilkan dari CCl4. Hasil ini mengindikasikan bahwa Fagraea racemosa menjanjikan untuk dikembangkan sebagai suplemen antioksidan. (Health Science Indones 2011;2:46-51)   Abstract Background: The ability of the liver in dealing with oxidative stress can be enhanced by consumption of exogenous antioxidants derived from nature. This study aimed to explore the hepatoprotective ability of Fagraea racemosa leaves methanolic extract against CCl4 exposure as a model of free radicals source. Methods: Three different doses (50, 100, 200 mg/kg bw) were administered orally to three treatment groups of Wistar rats (six Wistar rats each), respectively, once per day for 30 days. CCl4 injected intraperitoneally to those three groups, twice a week (1,5 ml/kg bw).  Two control groups were provided that were one normal control group and one CCl4 control group.  On the 30th day, the rats were killed and its liver examined with Haematoxyllin eosin staining. Histopathological changes were graded based on the degree of steatosis, hydropic degeneration, and inflammation. Data were analyzed with ANOVA and LSD post hoc (p≤0.05) using SPSS version 13.0 Results: The results showed improvement between the three treatment groups and the CCl4 control group about the degree of hydropic degeneration and inflammation (P ≤ 0.05). However, there were significant increased of steatosis 50 and 100 mg/kg bw treatment groups, before its significantly decrease at 200 mg/kg bw treatment group (2.5 g/kg). Conclusions: Fagraea racemosa leaves methanolic extract could protect liver from free radicals generated by CCl4. The result indicated that Fagraea racemosa has promising quality to be explored as antioxidant supplement. (Health Science Indones 2011;2:46-51)
Reducing public communication apprehension by boosting self confidence on communication competence Rachmi, Eva; Khotimah, Siti
Health Science Journal of Indonesia Vol 1, No 1 Des (2010)
Publisher : Badan Penelitian dan Pengembangan Kesehatan

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Abstrak Latar belakang: Dokter harus kompeten dalam berkomunikasi dengan sesame dokter ata dengan profesi lain. Pada Fakultas Kedokteran Universitas Mulawarman, beberapa mahasiswa cenderung diam pada saat pelatihan komunikasi public, yang tampaknya disebabkan oleh kecemasan saat berkomunikasi. Penelitian ini bertujuan untuk menganalisa kemungkinan ‘kepercayaan diri terhadap kemampuan komunikasi’ dan  ‘ketrampilan berkomunikasi’ sebagai factor resiko terjadinya ‘kecemasan dalam komunikasi publik’ Metode: Penelitian ini dilakukan pada 55 mahasiswa Fakultas Kedokteran Universitas Mulawarman. Kecemasan dalam komunikasi public diukur dengan Personal report of communication apprehension (PRCA-24), kepercayaan diri terhadap kemampuan komunikasi dengan Self perceived communication competence scale (SPCC), ketrampilan berkomunikasi didasarkan pada penilaian instruktur saat program pelatihan komunikasi, Data dianaliasa dengan regresi linear untuk mengidentifikasi factor yang dominan, menggunakan STATA 9.0 Hasil: Hasil penelitian menunjukkan hubungan negative antara kecemasan dalam public komunikasi dengan kepercayaan diri terhadap kemampuan komunikasi (koefisien regresi (KR) =-0.13; p=0.000; 95% derajat kepercayaan (DK) =-0.20; -0.52). Tetapi, terbukti tidak berhubungan dengan ketrampilan komunikasi (p=0.936). Diantara 12 trait kepercayaan diri terhadap kemampuan komunikasi, mahasiswa yang percaya diri saat berkomunikasi dengan sekelompok orang yang masih asing mempunyai tingkat kecemasan paling rendah (KR suaian=-0.13; DK=-0.21; 0.05; p=0.002). Kesimpulan: Semakin tinggi kepercayaan diri mahasiswa terhadap kemampuan komunikasinya akan semakin rendah tingkat kecemasannya. Untuk itu, fakulta kedokteran perlu memberikan kesempatan bagi mahasiswa mempraktekkan komunikasi public, terutama dengan berbicara kepada sekelompok orang asing. (Health Science Indones 2010; 1: 37 - 42) Kata kunci: berbicara, kelompok, kemampuan komunikasi ABSTRACT Background: A medical doctor should be competent in communicating with others. Some students at the medical faculty Universitas Mulawarman tend to be silent at public communication training, and this is thought to be influenced by communication anxiety. This study aimed to analyze the possibility of self-confidence on communication competence and communication skills are risk factors of communication apprehension. Methods: This study was conducted on 55 students at the medical faculty Universitas Mulawarman.  Public communication apprehension was measured using the Personal Report of Communication Apprehension (PRCA-24). Confidence in communication competence was determined by the Self Perceived Communication Competence scale (SPCC).  Communication skills were based on the instructor’s score during the communication training program. Data were analyzed by linear regression to identify dominant factors using STATA 9.0. Results: The study showed a negative association between public communication apprehension and students’ self confidence in communication competence [coefficient regression (CR) =-0.13; p=0.000; 95% confidence interval (CI)=-0.20; -0.52]. However, it was not related to communication skills (p=0.936). Among twelve traits of self confidence on communication competence, students who had confidence to talk to a group of strangers had lower public communication apprehension (adjusted CR=-0.13; CI=-0.21; 0.05; p=0.002). Conclusions:  Increased confidence in their communication competence will reduce the degree of public communication apprehension by students. Therefore, the faculty should provide more opportunities for students to practice public communication, in particular, talking to a group of strangers more frequently. (Health Science Indones 2010; 1: 37 - 42)
Gambaran Variasi Anatomy Vena Saphena Parva pada Cadaver Indonesia Danial, Dani; Nugroho, Hary; Rachmi, Eva; Ibrahim, Arie
ANATOMICA MEDICAL JOURNAL | AMJ Vol 2, No 2 (2019): Anatomica Medical Journal
Publisher : Universitas Muhammadiyah Sumatera Utara

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Abstract

Treatment of vein varicose that related to small saphenous vein is needed a good understanding of small saphenous vein anatomy and its’ variations. The purpose of this study investigates anatomy variations of small saphenous vein on Indonesians’ specimen base on cadaver dissected. We examine five pair of lower limb cadavers. Duplicating and branching patterns of small saphenous vein, and it’s relation to fascia were studied after exposing the superficial layers of the lower limb in Anatomy Laboratory of A.W Syahranie Hospital, Samarinda. This study found a small saphenous vein with accessory duplication in two pairs and a half of lower limb pair. In branching pattern, posterior crus region consist of two lower limbs with branch arise from 1/3 distal, one lower limb from 1/3 proximal and one lower limb from both in 1/3 distal and 1/3 medial. Small saphenous vein is located between the muscular fascia and superficial layer of membrane fascia in eight lower limbs. It can be said that this study get a clear describing of anatomy variations of small saphenous vein in Indonesian specimens base on cadaver dissected and also this study can support to further other research.