Articles

SUBCHRONIC TOXICITY TEST OF KEBAR GRASS EXTRACT OF N-HEXANE (BIOPHYTUM PETERSIANUM KLOTZSCH) ON WEIGHT, ADG AND VITAL ORGAN WEIGHT OF RAT (RATTUS NORVEGICUS) Sambodo, Priyo; Nurhayati, Dwi; Purwaningsih, Purwaningsih; Susmiati, Trini; Airin3, Claude Mona
Journal of Food and Pharmaceutical Sciences Vol 6, No 1 (2018): J. Food Pharm. Sci (January-April)
Publisher : Fakultas Farmasi, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (340.705 KB) | DOI: 10.14499/jfps

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The recent study was carried out to determine the effect of Kebar grass extract of N-hexane  (Biophytum petersianum Klotzsch) for 28 days peroral on weight, ADG and weight of vital organs of white rat. Forty male and female rats of Sprague Dawley strain aged 8 weeks were examined. The formulated rats were divided into four groups, group I (control), group II, III, IV (treatment), in which each consisted of five rats. The feed were given as much as 15 g/rat/day, while drinking ad libitum. In the control group, the rats were given solvent extract, group II, III and IV were given fraction of n-hexane of Kebar grass extract at 1 mg/kg BW, 5 mg/kg BW and 10 mg/kg BW peroral, respectively. Test preparation was given daily for 28 days, observation of toxic symptoms was performed every day while weighing was performed once every two weeks. Based on results obtained in this line of research, the findings indicated that Kebar extract administration for 28 days did not cause toxic symptoms in both male and female rats either in dose II, III or IV. Weight and ADG of male and female rats did not indicate significant differences between the control group and the treatment group. Keywords:  kebar grass, rats, subcronic toxicity test, OECD 407
The Impact of Green Tea on Blood Fluidity Improvement and Weight Loss Purwanto, Djoko Agus; Darmawati, Asri; Purwaningsih, Purwaningsih
Jurnal NERS Vol 10, No 2 (2015): Vol. 10 Nomor 2 Oktober 2015
Publisher : Universitas Airlangga

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Abstract

Introduction: Various studies have shown the beneficial effects of green tea, not only on cardiovascular diseases but also on type 2 diabetes. Method: In this study, the preparation of green tea water extract has been standardized to (-)-epigalocatechin gallate (EGCG), the major component of green tea. The role of green tea water extract on blood fluidity and diabetes diseases has been studied in 13 Fructose-Fed Rat (FFR). The rats were given high fructose diet ad libitum for one week and then combination with green tea water extract every day for 6 days. Results: The results show, green tea water extract can reduces 100 µL blood passage times of wistar rat significantly (p<0.01) by Micro-Channel Array Flow Analyzer (MC-FAN) instrument. Green tea water extract also had strong effect in reducing abdominal fat (p<0.05), blood glucose level (p<0.01) and body weight (p<0.01). Discussion: These results suggest that green tea water extract may has beneficial effects for the treatment of diabetes and reduce blood viscosity.  Keywords: green tea, (-)-epigallocatechin gallate, HPLC, blood fluidity, fructose-fed rat
Marketing Strategy To Increase Bed Occupancy Rate Purwaningsih, Purwaningsih; Yunitasari, Esti
Jurnal Ners Vol 3, No 1 (2008): Vol. 3 No. 1 April 2008
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (43.418 KB) | DOI: 10.20473/jn.v3i1.4987

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Introduction: A hospital is an institution for health care providing treatment by specialized staff and equipment, more often but not always providing for longer-term patient stays. Today, hospitals are very complex institution, not only survive in dynamic environment but also make a profit based on their services. The aimed of this research was to know marketing mix concept (product, price, place, promotion, people, process and provision of customer service) in formulating marketing strategy to increased Bed Occupancy Rate of Obstetric Gynecology Ward 2. Method: The population are health care personnel including midwife, midwife associate, administrator and also client or consumer. The variable were product, price, place, promotion, people, process and provision of customer service. Data were collected by using structured questionnaire. Result: The result showed that product (type of services, infrastructure and facility), relative price, comfortable and safe place, targeted promotion, trained human resources, standard process and provision of customer service are an important aspect to implement strategy marketing to increase Bed Occupancy Rate. Analysis: The result of this study has enlightened the importance of strategy marketing in health care services based on seven principle of marketing mix. Discussion: Implementation of marketing mix in obstetric gynecology ward 2 need to be considered.
KEANEKARAGAMAN JENIS DAN SEBARAN FAGACEAE DI INDONESIA Purwaningsih, Purwaningsih; Polosakan, Ruddy
ETHOS (Jurnal Penelitian dan Pengabdian) Vol 4 No.1 (Januari 2016) Ethos: Jurnal Penelitian dan Pengabdian (Sains & Teknologi)
Publisher : Universitas Islam Bandung

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Abstract

Fagaceae umumnya pohon, salah satu suku dengan jumlah jenis yang cukup besar ± 700 jenis di dunia tetapi sebagian besar tumbuh di belahan bumi utara. Di wilayah Malesia, ada lima marga yaitu Nothofagus, Castanopsis, Lithocarpus, Quercus dan Trigonobalanus dan jumlah jenis ± 180 dan sebagian besar di Indonesia tercatat 112 jenis. Penelitian ini dilakukan dengan studi literatur untuk menentukan keanekaragaman jenis Fagaceae di Indonesia serta distribusi dan pemanfaatannya. Fagaceae paling banyak tumbuh di Indonesia adalah marga Lithocarpus (60 jenis) dan Castanopsis (24 jenis), sementara Nothofagus (11 jenis) sebarannya hanya di Papua. Distribusi jenis Lithocarpus paling di Sumatera (29 jenis) dan Kalimantan (26 jenis), sementara Castanopsis paling banyak di Kalimantan (15 jenis). Untuk Nusa Tenggara tidak ditemukan jenis-jenis Fagaceae dan ke arah timur Indonesia semakin sedikit jumlah jenisnya, di Sulawesi dan Maluku hanya diketemukan satu jenis. Sebaran Fagaceae dipengaruhi oleh beberapa faktor, terutama tanah, iklim, dan ketinggian. Di Indonesia habitat tumbuh Fagaceae di hutan yang masih alami, tetapi ada beberapa yang mampu tumbuh di rawa seperti Nothofagus womersleyi. Berdasarkan ketinggian tempat (altitude) umumnya Fagaceae di hutan submontane dengan ketinggian 600-1500 m namun ada beberapa spesies yang mampu tumbuh hingga ketinggian >3000 m. Fagaceae yang memiliki sebaran luas (ditemukan di beberapa pulau) ada dua jenis yaitu Castanopsis acuminatissima dan Lithocarpus elegans. Pada umumnya pemanfaatan Fagaceae adalah kayunya untuk bahan bangunan dan furniture tetapi ada jenis Castanopsis yang dapat dimakan bijinya dan selain itu kulit kayu mengandung tanin bisa untuk pewarna.
UJI EKSTRAK N-HEXANA RUMPUT KEBAR (BIOPHYTUM PETERSIANUM KLOTZSCH) PADA TIKUS WISTAR HIPERKOLESTEROLEMIA Sambodo, Priyo; Purwaningsih, Purwaningsih; Baaka, Alnita; Susmiati, Trini; Airin, Claude Mona
Jurnal Sain Veteriner Vol 37, No 1 (2019): Juni
Publisher : Fakultas Kedokteran Hewan Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (493.167 KB) | DOI: 10.22146/jsv.48487

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This study was aimed to determine the secure level of the n-hexane extract of kebar grass on hypercholesterolemia rats based the acute oral toxicity test. Based the literature, no report on the toxic dosage before, initial dose was started at 300 mg/kg body weight (BW) and to be increased 2000 to 5000 mg/kg BW. Toxicity data were set for 24 hours and continued until 14 days after treatment for several parameters, i.e : toxicity symptoms, death of animals, changes in body weight and the manifestation of toxicity effects. At the end of the test, the rats were sacrificed and organs were taken for abnormalities (macroscopy). The results of this study showed that the administration of the n-hexane extract of grass kebar at all doses did not show the toxicity symptoms, mortality and body weight change. The absolute and relative weights and gross pathology observation of the internal organ were normal. Conclusions: the n-hexane extract of grass kebar is safe and the LD was determined on category 5, 50 unclassified or minimum practically non toxic
Analysis of Nurse’s Occupational Health in Managing Patients in Benyamin Guluh Hospital Kolaka Regency Tukatman, Tukatman; Sulistiawati, Sulistiawati; Purwaningsih, Purwaningsih; Nursalam, Nursalam
Jurnal NERS Vol 10, No 2 (2015): Vol. 10 Nomor 2 Oktober 2015
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (249.642 KB) | DOI: 10.20473/%oj.Ners102%y343-347

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Introduction: Occupational health and safety are a system designed to ensure a good safety and health in the workplace. Nurses have a higher risk of accidents and occupational diseases due to managing patients The goal of analyze the relationship or the influence of predisposing, enabling and reinforcing factors, and the concept of core and care in nurses’ safety and occupational health issue nurs in managing patient. Methods: Type of study is explanatory research using cross sectional design. Proportional random was chosen by consecutive sampling technique amounted to 100 respondents based on criteria. The variables measured were predisposing factors (knowledge, attitudes, beliefs and values), reinforcing factor (officers who became a role model), enabling factors (facilities, rules/regulation), core-care (interpersonal, concern), as well as safety and occupational health. Data were analyzed using Partial Least Square (PLS). Result and Analysis: Predisposing factors affecting safety and occupational health, value by t-count of 2.82 > t-table of 1.96. Reinforcing factors do not significantly affect occupational health and safety by t-count of 1.098 < t-table of 1.96. Enabling factors affecting occupational health and safety by t-count of 2.39 > t-table of 1. Factors of core and care factors affecting nurses’ safety and occupational health in managing patients in Benyamin Guluh Hospital, Kolaka Regency have t-count of 1.963 > t-table of 1.96. Discussion and Conclusion: Development of behavioral and nursing theories to nurses’ occupational health and safety showed R-square value of 39.5%. The new model structure are: predisposing factors (knowledge, attitudes, beliefs and values), enabling factors (facilities, rules / regulation), core (interpersonal relationships) and care (concern).Keywords: occupational health, behavior, nursing
GOOD HOMOSEXUAL BEHAVIOUR DECREASE PREVALENCE OF SEXUAL TRANSMITTED DISSEASE Purwaningsih, Purwaningsih; Widyawati, Ika Yuni; Firdaus, Mohammad Nur
Jurnal Ners Vol 3, No 2 (2008): Vol. 3 No. 2 Oktober 2008
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (273.372 KB) | DOI: 10.20473/jn.v3i2.4996

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Introduction: The homosexual behaviour were become indicators of sexually transmitted diseases’s (STDs) prevalencies. Prevalence of sexually transmitted diseases in homosexual community was very high but until recently study it was conducted sporadically. The objective of this study was to analyze the correlation of homosexual behaviour with prevalence of sexually transmitted diseases (STDs) in Mobile Clinic Community Centre of IGAMA collaborating with Public Health Centre Sumberpucung of Malang Regency. Method:  Analytic design with cross sectional methode was used in this study. The population were all visitors of Mobile Clinic Community Centre of IGAMA collaborating with Public Health Centre Sumberpucung of Malang Regency (353 people). Sample were 40 people who met to the inclusion criteria. The independent variable was homosexual behaviour and the dependent variable was prevalence of sexually transmitted diseases (STDs). Data for homosexual behaviour were collected by using questionnaire and indhept interview with content analyze and data for prevalence of sexually transmitted diseases (STDs) were collected by using laboratorium test for STDs. Result: The research result was presented in the form diagram, table of cross tabulation and analyzed by using Spearman Rho with significance level ρ=0.005. The result showed that there was correlation of homosexual knowledge (ρ=0.001), attitude (ρ=0.000) and  practice (ρ=0.000) with prevalence of STDs. Dsicussion:  It can be concluded that the better knowledge, attitude and practice of homosexual could be decrease prevalence of STDs. Futher studies are recomended to analyze the correlation between homosexual behaviour and prevalence of STDs with Health Believe approach.
REAKSI PASAR TERHADAP PENGUMUMAN PENERBITAN SUKUK MUDHARABAH DAN OBLIGASI KONVENSIONAL Purwaningsih, Purwaningsih; Khoiruddin, Moh.
Management Analysis Journal Vol 5 No 4 (2016): Managemant Analysis Journal
Publisher : Management Analysis Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/maj.v5i4.10915

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This research aims to analyse market reaction toward sukuk mudharabah and conventional bonds issue announcement that indicated with abnormal return and trading volume activity. Population in this research is all of sukuk mudharabah and conventional bonds issue announcement registered in IDX period 2012-2015. This research used event study with 21 days of windows period (t-10 to t+10). Samples of this research consist of 5 sukuk mudharabah issue announcements and 65 conventional bonds issue announcements based on purposive sampling method. Analysis methods used in this research are t-test and Paired Samples T-Test. The results of this research show that there are significant abnormal return around the date of sukuk mudharabah issue announcement on t-10, t-8, t-6, and wheres significant abnormal return around the date of conventional bonds issue announcement on t-7, t-3, t-1, t-3, t-4, t-7. In addition, there is no significant difference between trading volume activity before and after to sukuk mudharabah and conventional bonds issue announcement. The market react slow and prolonged so there is not happened  market efficiency semi-strong form in information and decision.  
Health Believe Model Implementation on The Analyze of Family Decision to Visit The Public Health Center Purwaningsih, Purwaningsih; Armini, Ni Ketut Alit; Susanti, Susanti
Jurnal Ners Vol 4, No 1 (2009): Vol. 4 No. 1 April-September 2009
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (296.367 KB) | DOI: 10.20473/jn.v4i1.5016

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Introduction : Dengue Haemorhagic Fever (DHF) is one of infecsius deseases. These deseases can have serious complications and kill the patients. Dengue Haemorhagic Fever (DHF) deseases that is suffered to the patients has become a heavy complication in Tembok Dukuh village. By the health belief model implementation, the patients got earlier response as soon as possible. The objective of the study was to analyze family’s decision for visiting Puskesmas in earlier response of Dengue Haemorhagic Fever (DHF). This descriptive analytic was conducted at work area of Puskesmas Tembok Dukuh Surabaya. The population was the family with Dengue Haemorhagic Fever (DHF) patient from Januari 2007 until July 2009. Method : Clustered design was used to take the sample. Total sample were 65 respondents, taken according to inclusion criteria. The independent variables were health belief model about perceived susceptibility, perceived seriousness, perceived benefits, perceived barriers, and cues to action. The dependent variable was family’s decision for visiting Puskesmas in earlier response of Dengue Haemorhagic Fever (DHF). Data was collecting using structured questionnaire. Data that had collected were later analyzed with frequency distribution of each category. Result : Result showed that perceived susceptibility most family was in middle category, perceived seriousness most family was in high category, most of family got the benefits, most of family also got the barriers, and all of the respondents have cues to action. The family’s decision to visit Puskesmas for the earlier Dengue Haemorhagic Fever (DHF) response  was founded in a few of family. Analysis :  It can be concluded that most of the family didn’t have a steady decisison to visit Puskesmas for the earlier Dengue Haemorhagic Fever response. It can be proved by there are most of family chose the others health service. Discussion : Health workers in Desease Eradication Departement (P2M) should sosialize the Puskesmas program  related with the earlier Dengue Haemorhagic Fever (DHF) response. So that, the family has believed that visiting Puskesmas is important for the earlier Dengue Haemorhagic Fever (DHF) response.
Pengaruh Penggunaan Rumput Kebar (Biophytum petsianum Clotzch) dalam Konsentrat Berdasarkan Kandungan Protein Kasar 19% terhadap Penampilan Kelinci Kayadoe, Martha; Faidiban, O R; Purwaningsih, Purwaningsih; Nurhidayati, Dwi
Sains Peternakan: Jurnal Penelitian Ilmu Peternakan Vol 10, No 2 (2012): Sains Peternakan
Publisher : Universitas Sebelas Maret (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/sainspet.10.2.64-68

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The objective of this study was to investigate the performances of rabbit using several levels of Kebar grass in concentrate, i.e. 0, 5, 10 and 15%, according to protein requirement 19%. Research designed by using Randomized Design Group and each treatment was replicated two times. Data were analyzed using Analysis of Variance and Continued with LSD test. The addition of kebar grass concentrates had no effect in ration and feed efficiency, but significantly affect body weight gain in treatment of 10% and 15% compared to without addition (0%) of kebar grass and 5%. The addition of kebar grass did not affect palatability.Key words : kebar grass, rabbit, concentrate, formulations