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Journal : Al-Kimia

Identifikasi dan Karakterisasi Senyawa Bioaktif Antikanker dari Ekstrak Etanol Kulit Batang Kayu Bitti (Vitex cofassus) Nuraini, Nuraini; Ilyas, Asriani; Novianty, Iin
Al-Kimia Vol 3, No 2 (2015): December
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v3i2.1668

Abstract

Bitti wood (Vitex cofassus) is one of the plants in Verbenaceae family and known by the people of South Sulawesi as the building material. The aims of this research  is to identify and characterize  the anticancer bioactive compound in ethanol extract of vortex Bitti wood (Vitex cofassus) and to determine the bioactivity value. This research uses extraction and fraction method, identification uses thin layer chromatography (TLC) and phytochemical test to know metabolism secunder and characterization with FTIR. The result from isolation shows that the amorf shape with 18 mg has white and yellow colour. The purification is conduted by using spectroscopy test FTIR. The result shows that the crystal has flavonoids compound which is solid with phytochemical test like positive product by using FeCl3 5%, NaOH 10% and H2SO4 P. Thick extract, fraction combination and amorf continued with toxicity test with the animal test Artemia salina Leach it uses Brine Shrimp Lethality test (BST) method. LC50 value which is gotten the three samples is thick extract 29,51 ppm, combination fraction 169,82 ppm and amorf 562,34 ppm.
Co-Authors A. Djulardi A. Yuniza A.T. Umiarti Abadi, Musram Abdul Kahar Abidin, Nurul Adnan Syam Agus Taufik Mulyono Alfian, Rizki Alfian, Rizki Alfian, Rizki Alfian, Rizki Andana, Adi Anggraini, Betty Anip Dwi Saputro, Anip Dwi Arico, Zulfan - Arnoli, Zulmi Asni Johari Asriani Ilyas Azhar Muttaqin, Azhar Budiartha, I.W. Cahyani, Mita Chandra, Karlina CINDY CINDY Daulay, Lili Yuspita Dewi S, Chandra Dewi, Y. L. Dian Agustina Dian Rusmanawati Disafitri, R. Djulardi, Ade Dwi Kurniani Dyah Kusuma, Farida Halis Eka Sofia Agustina elida elida Elsje Theodora Maasawet Fadhilah, Raudhatul Febrian, R. Fenny Trisnawati Fitriani Fitriani Fitrianingsih Fitrianingsih H. Hafid H., Wahidyanti Rahayu H.S. Arifin, Nurhayati Hafnati Rahmatan Hamdan Alawi Haque, Marissa harahap, Miswaruddin Harapin Hafid Harefa, Dalizaro Hari Nugroho Hasibuan, Moh. Sanjiva Refi Heriyani, Eka Hidayat, Zikril Hira Helwati Imani, Siti Rohmatul Imelda Imelda Inderawati, Inderawati Inderawati, Inderawati Indra Suharman Iqbal Iqbal Irvan, Aidil Irwansyah Irwansyah Ismida, Yulina Isnain Effendi, Isnain Iwan Ardian, Iwan Jalil, Zakaria A Kasmita Kasmita Kiki Yolanda, Kiki La Ode Arsad Sani Laili Rahayuwati, Laili M Ali Sarong, M Ali Mahata, M. E. Makhdalena Makhdalena, Makhdalena Makrina Tindangen, Makrina MARIA ENDO MAHATA Marwan Marwan Masbirorotni Masbirorotni, Masbirorotni Mbina Pinem Mega Asiska Ninda Pratiwi, Mega Asiska Ninda Mega Asiska, Mega Mirzah Mirzah Monalisa Monalisa Muhammad Ali Husni muhammad Diwan, muhammad Muhammad Rais Muhammad Rizki Saputra, Muhammad Rizki Muhammad Yusuf Mujib Mujib, Mujib Munthe, Betti Suryati Murniana Murniana Muslim Muslim Muslimin Muslimin Mustafa Kamal NAFRIAL, NAFRIAL Nailufar, Balqis Nainggolan, Sri Faulina Nasri, Rizfaldi Naziah, Naziah Netti Aryani Niken Ayu Pamukas NOPIANTI, NOPIANTI Novianty, Iin Nunung Fajaryani, Nunung Nuraysah, Intan NurKhairin, Fibriyani Nurliza Nurliza Nurul Iman, Nurul Nusdiani Nusdiani, Nusdiani Pain Pati, Petrus Paulus Pandiangan, Tito Fresly Pangaribuan, Ayu Rayuni Pareira, Novica Christiani Pargito Pargito Parimartha, I.K.W. Pratama, Rama Arif Puspita, Yolanda Putri TM, Risma Putri, B.R.T. Putu Nara Kusuma Prasanjaya Rahim Aka Rajagukguk, Ronald Hasudungan Rasman Rasman Ratnasari, Diyannita Ray March Syahadat Retnaningsih Retnaningsih Revis Asra Ridha DS, Muhammad Rina Herartri, Rina Rinaldi Rinaldi Rindang Ekawati Rionaldi, Rionaldi Riyanto Djoko Rusli Badaruddin S. Hafiz S.A Latif S.A. Latif Sabhan Sabhan Sabrina Sabrina Sani, Arsad Sayuti, K. Setyabudi, Irawan Sigit Dwi Laksana, Sigit Dwi Silfeni Silfeni Simbolon, Antonius KAP Sirait, Desy Kristina Ayu Siti Samhati Sri Jayanthi, Sri Sri Kartikowati Sri Wahyuni Sudjarwo Sudjarwo Suherman Suherman Sukamdi Sukamdi Sukendi Sukendi, Sukendi Sulaiman Sulaiman Sumarno Sumarno Suparta, I.N. Syafruddin Nasution Syamsudin Syamsudin Syamsul Rizal Tanggela, Ardian taruli, sihombing Tasse, A. M. Toba, R. D. S. Tri Dewi Andalasari Uran, Rofinus Seri Utami, M.Kes, Dr. Tri Niswati Vitaloka, Nia Wahyudi Wahyudi Widyawati, Ratih Widyawati, Ratih Winda Winda Wirnelis Syarif Y. Marlida Yafisham Yafisham, Yafisham Yeye Susilowati Yogia Prihartini Yulisari, Irma Zainaro, M. Arifki Zainaro, Muhammad Arifki