Articles

Found 2 Documents
Search
Journal : Jurnal Anestesi Perioperatif

Hubungan antara Rasio Neutrofil-Limfosit dan Skor Sequencial Organ Failure Assesment pada Pasien yang Dirawat di Ruang Intensive Care Unit

Jurnal Anestesi Perioperatif Vol 1, No 3 (2013)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Original Source | Check in Google Scholar | Full PDF (1147.177 KB)

Abstract

Respons fisiologis sistem imunitas terhadap inflamasi sistemik adalah peningkatan jumlah neutrofil dan penurunan jumlah limfosit atau peningkatan rasio neurofil-limfosit (RNL). Penelitian ini bertujuan untuk melihat hubungan inflamasi sistemik yang ditandai peningkatan RNL terhadap kegagalan fungsi organ ditandai dengan skor Sequencial Organ Failure Assessment (SOFA) pada pasien yang dirawat di Intensive Care Unit (ICU). Penelitian ini adalah penelitian observasional dengan rancangan penelitian cross sectional. Penelitian dilakukan dengan mengobsevasi RNL dan skor SOFA pada jam ke-0, jam ke-24, dan jam ke-48 dari 78 pasien yang dirawat di ICU Rumah Sakit Dr. Hasan Sadikin Bandung periode Desember 2012–Februari 2013 yang terbagi ke dalam 3 kategori sepsis A, B, dan C. Data penelitian dianalisis menggunakan analisis bivariabel dengan Uji Korelasi Pearson dan Spearman. Hasil penelitian menunjukkan hubungan antara RNL dan skor SOFA terhadap kategori sepsis masing-masing (p<0,001). Uji Korelasi Pearson didapatkan hubungan antara RNL dan skor SOFA (p<0,05; R=0,63). Simpulan, terdapat hubungan antara keadaan inflamasi sistemik yang ditandai dengan RNL dan kegagalan fungsi organ yang ditandai dengan skor SOFA pada pasien yang dirawat di ICU RS Dr. Hasan Sadikin Bandung.Kata kunci: Intensive care unit, rasio netrofit-limfosit, sequencial organ failure assesment Relationship between Neutrophil Lymphocyte Ratio and Sequential Organ Failure Assesment Score in the Intensive Care Unit patientsAbstractPhysiological response of immune system against systemic inflammation involves an increased level of neutrophils and a reduction of lymphocyte or an increase of neutrophil-lymphocyte ratio (RNL). The aim of this study was to identify the relationship between systemic inflammation, characterized by increasing in RNL on organ malfunction, assessed by Sequential Organ Failure Assessment (SOFA) score in Intensive Care Unit (ICU) patients. This study was a observational study with cross sectional design. This study was conducted by observing RNL and SOFA score at 0, 24th and 48th hour of 78 patients treated in the ICU Dr. Hasan Sadikin Hospital Bandung in December 2012–February 2013. Patients were divided into 3 categories of sepsis A, B and C. This study showed that there was a relationship between RNL, SOFA scores and sepsis categories (p<0.001). Pearson Correlation Test showed that there was relationship between RNL and SOFA scores (p<0.05, R= 0.63). In conclusion, there is a relationship between systemic inflammatory condition, characterized by RNL and organ failure, characterized by the SOFA score, in patients treated in the ICU Dr. Hasan Sadikin Hospital Bandung.Key words: Intensive care unit, neutrophil-lymphocyte ratio, sequential organ failure assesment DOI: 10.15851/jap.v1n3.198

Hubungan antara Rasio Neutrofil-Limfosit dan Skor Sequencial Organ Failure Assesment pada Pasien yang Dirawat di Ruang Intensive Care Unit

Jurnal Anestesi Perioperatif Vol 1, No 3 (2013)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Original Source | Check in Google Scholar

Abstract

Respons fisiologis sistem imunitas terhadap inflamasi sistemik adalah peningkatan jumlah neutrofil dan penurunan jumlah limfosit atau peningkatan rasio neurofil-limfosit (RNL). Penelitian ini bertujuan untuk melihat hubungan inflamasi sistemik yang ditandai peningkatan RNL terhadap kegagalan fungsi organ ditandai dengan skor Sequencial Organ Failure Assessment (SOFA) pada pasien yang dirawat di Intensive Care Unit (ICU). Penelitian ini adalah penelitian observasional dengan rancangan penelitian cross sectional. Penelitian dilakukan dengan mengobsevasi RNL dan skor SOFA pada jam ke-0, jam ke-24, dan jam ke-48 dari 78 pasien yang dirawat di ICU Rumah Sakit Dr. Hasan Sadikin Bandung periode Desember 2012–Februari 2013 yang terbagi ke dalam 3 kategori sepsis A, B, dan C. Data penelitian dianalisis menggunakan analisis bivariabel dengan Uji Korelasi Pearson dan Spearman. Hasil penelitian menunjukkan hubungan antara RNL dan skor SOFA terhadap kategori sepsis masing-masing (p<0,001). Uji Korelasi Pearson didapatkan hubungan antara RNL dan skor SOFA (p<0,05; R=0,63). Simpulan, terdapat hubungan antara keadaan inflamasi sistemik yang ditandai dengan RNL dan kegagalan fungsi organ yang ditandai dengan skor SOFA pada pasien yang dirawat di ICU RS Dr. Hasan Sadikin Bandung.Kata kunci: Intensive care unit, rasio netrofit-limfosit, sequencial organ failure assesment Relationship between Neutrophil Lymphocyte Ratio and Sequential Organ Failure Assesment Score in the Intensive Care Unit patientsAbstractPhysiological response of immune system against systemic inflammation involves an increased level of neutrophils and a reduction of lymphocyte or an increase of neutrophil-lymphocyte ratio (RNL). The aim of this study was to identify the relationship between systemic inflammation, characterized by increasing in RNL on organ malfunction, assessed by Sequential Organ Failure Assessment (SOFA) score in Intensive Care Unit (ICU) patients. This study was a observational study with cross sectional design. This study was conducted by observing RNL and SOFA score at 0, 24th and 48th hour of 78 patients treated in the ICU Dr. Hasan Sadikin Hospital Bandung in December 2012–February 2013. Patients were divided into 3 categories of sepsis A, B and C. This study showed that there was a relationship between RNL, SOFA scores and sepsis categories (p<0.001). Pearson Correlation Test showed that there was relationship between RNL and SOFA scores (p<0.05, R= 0.63). In conclusion, there is a relationship between systemic inflammatory condition, characterized by RNL and organ failure, characterized by the SOFA score, in patients treated in the ICU Dr. Hasan Sadikin Hospital Bandung.Key words: Intensive care unit, neutrophil-lymphocyte ratio, sequential organ failure assesment DOI: 10.15851/jap.v1n3.198

Co-Authors A. Muthalib Nawawi Agus Naryoso Agustinus, Stefan Ahmad Ashari Alessandro Christoforus Baramuli Amal Gamasi T.R Andhika Putra Nugraha Andi Taru Nugroho NW Angela Atik Setiyanti Anjik Sukmaaji Aprillia N S Arditya Drimulrestu Arfianto Adi Nugroho, Arfianto Adi Arinda Putri Oktaviani, Arinda Putri Ariya Dwika Cahyono, Ariya Dwika Astuti Dwi Wahyu Pertiwi Bahrul Ilmi Baskoro Rochaddi Beta Himawan Putra, Beta Himawan Brillian Barro Vither Budiantoro, Cahyo Budiyantoro, Cahyo Choirul Ulil Albab, Choirul Ulil David Fredy Christiyanto, David Fredy Destika Fajarsylva Anggraini Diah Rukmi Ambarwati, Diah Rukmi Dimas Herdy Utomo Djoko Setyabudi Dody Tisna Kurniawan DR Sunarto Dr. Sunarto Dubha Kaldota Diptapramana, Dubha Kaldota Dwi Haryo Ismunarti Edi Winarko Ekawati Marhaenny Dukut, Ekawati Marhaenny Fariza Khumaedi Fatwa Ramdani, Fatwa Fauzan Faiz Fetiyana Luthfi Prihandini, Fetiyana Luthfi Galih Arum Sri Gelar Mukti Geuis Puspita Dewi Ghanes Eka Putera Handono Priambodo, Handono Hani Faurizka Hapsari Dwiningtyas Hardi Warsono Hedi Pudjo Santosa Hettyca Astuningdyas Hutama, Adhi Setya Ikhsan, Subkhan Nur Imanda Aulia Akbarian Indartono Indartono Indra Prayoga Irawati Sri Wulandari Joyo NS Gono Karina Puspadiati Kevin Devanda Sudjarwo Khabib Mustofa Kiky Rizkiana Krisna Adhi Nugroho Kurniawan, Perwita Lintang Andini Lintang Ratri Rahmiaji Lintang Ratri Ramiaji M Bayu Widagdo M Yulianto Marliana Nurjayanti Nasoetion Marliani Marliani Maya Putri Utami, Maya Putri Meldra, Delia Mellisa Indah Purnamasari Much Yulianto Much. Yulianto Muchammad Yulianto NANIK WAHYUNI Nastangin, Yahri Ni Made Dinna Caniswara Nilna Rifda Kholisha Novitai Ika Putri, Novitai Ika Nur Aini Nurist Surayya Ulfa Nurrist Suraya Ulfa Nurriyatul Lailiyah, Nurriyatul Oithona Gracelia R. Hutabarat, Oithona Gracelia R. Osa Patra Rikastana, Osa Patra Pandu Hidayat, Pandu Pradipta Angga Saputra, Pradipta Angga Pramudia, Haris Probo Y. Nugrahedi Renis Susani Karamina Retno Indah Rokhmawati, Retno Indah Reza Rahardian Pratama Ricki Apriliono Rika Novitasari Sarah Tri Rahmasari Seno Darmanto Shafira Indah Muthia Sri Budi Lestari Sri Hartati Sri Nofidiyahwati Sujadi Sujadi Sulastri _ Sunarto Sunarto Suwarman - Tandiyo Pradekso Taufik Suprihartini Taufik Suprihatini Techn Khabib Mustofa Teguh Sutanto Theophilus Erman Wellem Tineke Kristina Siregar Titik Djumiarti Tommy Ardianto Totok Suwanda Tri Yoga Adibtya Tama, Tri Yoga Adibtya Triyono Lukmantoro Turnomo Rahardjo Ulya Anggie Pradini Vidya Ayunita Wijaya, Agustinus Fritz Wiwid Noor Rakhmad Yoga M Pamungkas Yos Richard Beeh Yuanisa Meistha Yudha Setya Nugraha Yulistra Ivo Azhari Yunita Utami, Yunita