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PENGARUH JENIS INOKULUM TERHADAP PRODUKSI ASAM STI´RAT

STIFAR - Sekolah Tinggi Ilmu Farmasi Vol 3, No 2 (2008)
Publisher : STIFAR - Sekolah Tinggi Ilmu Farmasi

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Abstract

Aspergillus niger is the highest citric acid producer. It will be better if other species like yeast can also produce citric acid faster and greater. Mold and yeast were inoculated in medium containing glucose as carbon source. Medium was shaked 7 x 24 hours where every 24 hours some medium sample was taken to measure citric acid concentration using volumetric method with neutral reaction. The data was analysed using two way anova. The result showed that yeast produced citric acid but not more than mold. In 7 x 24 hours citric acid concentration increased. It caused by fermentation maximum. It was concluded that citric acid production was influenced by the different inoculums species.   Keywords : inoculum, fermentation, citric acid

UJI ANTI DIARE INFUSA DAUN MIMBA (Azadirachta indica Juss) TERHADAP MENCIT JANTAN GALUR SWISS

STIFAR - Sekolah Tinggi Ilmu Farmasi Vol 8, No 2 (2013)
Publisher : STIFAR - Sekolah Tinggi Ilmu Farmasi

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Abstract

This study aims to determine the efficacy of neem leaf infusion antidiarrheal (Azadirachta indica Juss.) against male mice strain Swiss, and to determine the effective dose infusion of neem as antidiarrheal. Object of this study was the time of the occurrence, duration of diarrhea, and stool consistency and number of male mice strains Swiss. Samples of fresh neem leaves is used in the preparations made ​​by the infusion technique is random sampling . A 25 of mice was divided into 5 groups consisting of groups I- III were given neem leaf infusion dose of 68.12 mg/kgbw; 204.36 mg/kgbw and 613.08 mg/kgbw, group IV as a positive control group that were given loperamide HCl dose of 0.73 mg/kgbw, and group V as a negative control group that were given 0.75 ml of oleum ricini. All administration is done orally. Observations include the time of occurrence of diarrhea , duration of the course of diarrhea, stool consistency and number of each were evaluated statistically by Anova method and post- ANOVA test . The results showed that Infuse leaves of neem has antidiarrheal efficacy of male mice strain Swiss. Neem leaf infusion at a dose of 204.36 mg/kgbw and 613.08 mg/kgbw have antidiarrheal effects comparable to loperamide HCl dose of 0.73 mg / kgbw.   Keyword: infusa, Mimba leaves, diarhea

STUDI ETNOFARMASI SUKU DONDO KECAMATAN DONDO KABUPATEN TOLITOLI SULAWESI TENGAH

Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Vol 1, No 2 (2015): (October 2015)
Publisher : Universitas Tadulako

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Abstract

This study aims to inventory and to record plants and their parts used as medicine by Dondo Tribe in Dondo Subdistrict, Tolitoli Regency, Central Sulawesi. This research is a descriptive study using qualitative methods and snowball sampling technique through open-ended interviews to 4 informants using questionnaire. The results showed that 56 plant species divided into 32 familia were used as medicine. The most widely used plant was from Euphorbiaceae family as much as 11%. Parts of plant which were used included leaf, petiole, stem, bark, flower, fruit, seed, rhizomes, tuber, and herb. Part of plant widely used was the leaf with percentage of utilization as much as 62%. The people of Dondo Tribe in Tolitoli District use the plants for treatment of illness, recovery, and maintenance of health. The methods of processing included decocting, mashing, roasting, burning, squeezing, and brewing the parts of the plant. The ways of using included drinking, eating, chewing, smearing, dropping, affixing/compressing, attaching, and rubbing the plant preparations on the sore spot as well as inhaling the fumes, and mixing it with water for bathing

KAJIAN ETNOFARMASI ETNIK BUNGKU DI KECAMATAN BUNGKU TENGAH KABUPATEN MOROWALI PROVINSI SULAWESI TENGAH

Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Vol 2, No 2 (2016): (October 2016)
Publisher : Universitas Tadulako

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Abstract

This study aims to find out and to inventory the types and parts of plants as well as to dig up information about ways of their utilization as remedy used by Bungku people “To Bungku”. It was conducted from August to December 2015 in Bungku Subdistrict, Central Bungku, Morowali Regency, Central Sulawesi. This research is a descriptive study using qualitative methods and snowball sampling technique on 12 informants through data collection by questionnaire. Results of this etnopharmacy study revealed that there were 62 species of medicinal plants divided into 34 familia. The most widely used plants came from familia Euphorbiaceae, Fabaceae and Zingiberaceae, each was as many as 8%. Parts of plant including roots, stems, leaves, flowers, fruits, seeds and bulbs were used in accordance with their function. Leaves were the ones used with the highest percentage (50%). Bungku people used medicinal plants to treat diseases such as kidney stone, diabetes, hemorrhoids, diarrhea, abscess, candidiasis, gout, cancer, hypertension, hypercholesterolemia, dyspepsia, cough, abdominal pain, malaria, hematuria, skin inflammation, headache, fever, bronchitis, dysentery, asthma, stroke, gallstones, urinary tract infections, broken bones, nail-punctured, wound ulcers, burns, hepatitis, appendicitis. Ways of the utilization were very diverse such as boiling then drinking the decoction; crushing then rubbing on the necessary skin; attaching to the body; squeezing then drinking the juice; and heating on the fire. Processing by boiling has the largest percentage, as much as 54%

Uji Aktivitas Antibakteri Ekstrak Serbuk Gergaji Kayu Eboni (Diospyros celebicaBakh.) Terhadap Bakteri Staphylococcus aureus dan Escherichia coli

Biocelebes Vol 12, No 1 (2018)
Publisher : Biocelebes

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Abstract

Ebony (Diospyros celebica Bakh.) is one of the beneficial plants from ebenaceae, especially in traditional medicine. The sawdust extract containing chemical compounds such as tannins, saponins and terpenoids. This research were aimed to determine the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) also to identified the active compounds from sawdust extracts of D. celebica Bakh. against Staphylococcus aureus and Escherichia coli. The Research methods include extraction using maceration method by ethanol 96%. MIC and MBC determination using dilution and diffusion methods. The Results showed that MIC value of S.aureus and E. coli were 6% and 7%, respectively. While MBC value of S. aureus and E. coli were 12% and 13%, respectively. Identification of chemical compounds were determined by Thin Layer Chromatography (TLC) bioautography method by 10% H2SO4 and anisaldehid-sulfuric acid reagent spray. There were two chemichal compounds that produced, saponin and terpenoid.

STUDI TANAMAN BERKHASIAT OBAT SUKU MORI DI KECAMATAN PETASIA, PETASIA BARAT, DAN PETASIA TIMUR KABUPATEN MOROWALI UTARA SULAWESI TENGAH

Biocelebes Vol 12, No 1 (2018)
Publisher : Biocelebes

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Abstract

This study aims to conduct an inventory, knowing how to use and organs of plants used as medicine by Mori Tribal in Petasia, Petasia and East Petasia District, West North Morowali Regency of Central Sulawesi. This study used qualitative methods and sampling techniques that snowball sampling, with open-ended interview techniques interview on media 9 informants obtained using a questionnaire. Based on the results of research known as 79 species of medicinal plants, 2 of which can not be identified and divided into 45 familia used as a medicine. Plants are most widely used is of familia Euphorbiaceae as many as 8 species. Organs of plants used include leaves, stems, fruits, rhizomes, seeds, bark, flowers, bulbs, herbaceous roots and sap. Organ plant is widely used is the leaves that percentage utilization is 58%. Mori Tribal communities in the District, West Petasia and East Petasia North Morowali District use medicinal herbs to treat the disease, healing and health maintenance. The cooking methods include boiling water, brewed, boxed, taped, squeezed, scrubbed/smeared, chewed and consumed directly, drops, and sprayed. How to use include drunk, eaten, chewed and consumed directly, polished/smeared, attached, dropped, and chewed and sprayed on the affected area.

Aktivitas Antibakteri Ekstrak Etanol Daun Jarak Merah (Jatropha gossypifolia) Terhadap Bakteri Escherichia coli dan Staphylococcus aureus

Natural Science: Journal of Science and Technology Vol 7, No 1 (2018): Volume 7 Number 1 (March 2018)
Publisher : UNIVERSITAS TADULAKO

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Abstract

dengan Jarak Pagar (Jatropha curcas) yang sebelumnya telah terbukti memiliki aktivitas antibakteri. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri, konsentrasi optimum antibakteri dan senyawa yang berperan terhadap aktivitas antibakteri dari ekstrak etanol daun jarak merah (Jatropha gossypifolia L.) terhadap Staphylococcus aureus dan Escherichia coli. Ekstraksi senyawa aktif menggunakan metode maserasi dengan pelarut etanol. Pengujian aktivitas antibakteri dilakukan dengan varian konsentrasi 20%, 40%, 60%, 80% dan 100% dengan metode difusi agar. Hasil penelitian menunjukkan bahwa ekstrak etanol daun jarak merah memiliki aktivitas antibakteri terhadap            S.aureus dan E.coli dengan konsentrasi optimum penghambat pertumbuhan bakteri yaitu 60%         (S.aureus) dan 80% (E.coli). Berdasarkan pengujian bioautografi dan KLT dengan eluen                   n-heksana:etil asetat (1:2) menggunakan pereaksi kromogenik senyawa yang diduga berperan terhadap aktivitas antibakteri adalah terpenoid

STUDI ETNOFARMASI SUKU KAILI MOMA DI KECAMATAN KULAWI, KABUPATEN SIGI, PROVINSI SULAWESI TENGAH

Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Vol 3, No 1 (2017): (March 2017)
Publisher : Universitas Tadulako

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Abstract

This study aims to inventory and to know the ways of utilization as well as parts of the plants which have been used by people of Kaili Moma Tribe in Kulawi Subdistrict, Sigi Regency, Central Sulawesi. This research is a descriptive study which used qualitative methods and purposive sampling technique through open-ended interviews to 87 people of Kaili Moma Tribe using questionnaire. The results of this study showed that there were 51 species of plants, classified into 29 familia, used as remedies (traditional medicine) for the treatments of 41 types of disease. The most widely used plants came from family Lamiaceae with percentage of 17%.  The parts of plant used by the people included leaves, fruits, stems, tubers, roots, rhizomes, seeds, herbs, flowers and thorns. Part of the plants most frequently used as remedies is leaf with percentage of 49%. Ways of the plants utilization were very diverse, such as boiling; squeezing, and pounding. The people use them in ways of drinking, eating, rubbing, and affixing them to the affected part.

PRODUKSI PROTEIN SEL TUNGGAL DARI KULTUR Rhizopus oryzae DENGAN MEDIUM LIMBAH CAIR TAHU

Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Vol 2, No 2 (2016): (October 2016)
Publisher : Universitas Tadulako

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Abstract

Tofu wastewater is the origination of tofu’s production process that can degrade the quality of the environment if not handled properly. Another impact of this waste is the potential attack that could evoke the diseases such as diarrhea, skin diseases, and other illnesses for people who use the stream flow that has been polluted by this wastewater. However, the high-carbohydrate and protein of this waste may allow it to be used more as a microbial growth substrate to produce a Single-cell Protein. The purpose of this study is to determine the optimum incubation time and the highest protein content of Rhizopus oryzae in the medium of tofu wastewater based on the calculation of protein content percentage and the analysis of cell dry mass. And to know the optimum pH growth with the variation of pH growth which is about 4, 5, and 6. The calculation is performed in accordance with the fermentation time at 24, 48, and 72 hours. Total protein content calculated by the Kjeldahl method. The results showed the highest protein content obtained in the incubation period to 48 hours with an average percent of protein about 0.47%, 0.47%, 0.46% and a mass of cell with an average value of 0.77%, 0, 84% and 0.91%. The optimum pH of Rhizopus oryzae growth in the medium of tofu wastewater is about 5 pH. It can be concluded that the wastewater of tofu potentially used as a growth substrate of Rhizopus oryzae. Keywords: Wastewater of Tofu, Single-cell Protein, Rhizopus oryzae.