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Polimorfisme Gly972Arg Gen IRS-1 dan Cys981Tyr Gen PTPN1 sebagai Faktor Risiko pada Sindrom Metabolik dengan Riwayat Berat Bayi Lahir Rendah Permana, Hikmat; Nugraha, Gaga Irawan; Kariadi, Sri Hartini K. S.
Majalah Kedokteran Bandung Vol 44, No 3 (2012)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Peningkatan prevalensi obesitas terjadi di seluruh dunia dan dapat mengenai semua tingkatan usia. Faktor risiko peningkatan sindrom metabolik berhubungan dengan perubahan gaya hidup, obesitas, dan berat lahir rendah. Penelitian ini dilakukan bertujuan menganalisis genotipe IRS-1, genotipe PTPN1, dan berat bayi lahir rendah (BBLR) sebagai risiko terhadap sindrom metabolik. Pada tahun 2009 terkumpul sebanyak 97 BBLR dan 100 bayi berat lahir normal (BBLN) berusia 20–21 tahun. Penelitian kohort retrospektif ini merupakan bagian penelitian kohort sebelumnya di kecamatan Tanjung Sari pada tahun 1989. Peran genotipe IRS-1, genotipe PTPN1, dan BBLR terhadap sindrom metabolik diuji dengan regresi logistik multipel. Hasil penelitian menunjukkan tidak terdapat hubungan bermakna genotipe IRS-1 dan PTPN1 dengan faktor-faktor sindrom metabolik, tetapi hanya genotipe IRS-1 berhubungan signifikan dengan trigliserida (p=0,006). Polimorfisme Gly972Arg gen IRS-1 pada BBLR mempunyai nilai prediksi terhadap peningkatan tekanan darah diastol, lingkaran perut, dan trigliserida. Polimorfisme Cys981Tyr gen PTPN1 menunjukkan faktor risiko terhadap tekanan darah sistol dan kolesterol high density lipoprotein (HDL). Polimorfisme Gly972Arg gen IRS-1 merupakan faktor dominan sebagai penyebab peningkatan tekanan darah diastol, lingkaran perut, dan trigliserida. Simpulan, polimorfisme Cys981Tyr gen PTPN1 merupakan faktor risiko peningkatan tekanan darah sistol dan kolesterol HDL. Bayi berat lahir rendah merupakan faktor risiko peningkatan gula darah puasa. [MKB. 2012;44(3):170–8].Role of Polymorphism Gly972Arg Gene IRS-1 and Cys981Tyr Gene PTPN1 as Risk Factors in Metabolic Syndrome with History of Low Birth WeightIncreasing prevalence of obesity occurs worldwide and can affect all ages levels. Risk factors of increasing metabolic syndrome were associated with changes in lifestyle, obesity and low birth weight (LBW). This study was aimed to analyze the genotype IRS-1, genotype PTPN1 and LBW in metabolic syndrome risk factors. In 2009, this restrospective cohort study was comprised of 97 LBW and 100 normal birth weight (NBW), aged 20–21 years old, from the previous cohort study in District Tanjung Sari since 1989. The role of IRS-1 gene, PTPN1 gene and LBW in the metabolic syndrome factors were analyzed using multiple logistic regressions. The result showed there were no significant relationship between IRS-1 and PTPN1 genotype with metabolic syndrome factors but only IRS-1 genotype was significantly associated with trygliceride (p=0.006). Gly972Arg IRS-1 gene polymorphism in LBW has predictive value of increasing diastolic blood pressure, waist circumference and trygliceride. Cys981 Tyr PTPN1 gene polymorphism showed a risk factor for systolic blood pressure and high density lipoprotein (HDL) cholesterol. Gly972Arg IRS-1 gene polymorphism was a dominant factor to increase diastolic blood pressure, waist circumference and trygliceride. In conclusions, Cys981 Tyr PTPN1 gene polymorphism is a risk factor of increased systolic blood pressure and HDL cholesterol, and LBW is the risk factor increasing fasting glucose level. [MKB. 2012;44(3):170–8]. DOI: http://dx.doi.org/10.15395/mkb.v44n3.137
Pengaruh Pemberian Jeruk dengan Nanas pada Kadar Malondialdehid Plasma Subjek Terpapar Polusi Gas Buang Kendaraan Bermotor Yusnita, -; Nugraha, Gaga Irawan
Majalah Kedokteran Bandung Vol 45, No 2 (2013)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Faktor lingkungan seperti polusi udara akibat gas buang kendaraan bermotor dapat meningkatkan pembentukan radikal bebas di dalam tubuh. Hasil penelitian Departemen Teknik Lingkungan Institut Teknologi Bandung (ITB) pada Desember 2006 menunjukkan kecenderungan peninggian polusi udara antara lain terjadi di tempat yang menjadi pusat kemacetan khususnya di kawasan padat lalu lintas di Kota Bandung seperti di Jalan Merdeka. Kadar radikal bebas di dalam tubuh dapat diketahui dengan mengukur kadar malondialdehid (MDA) plasma. Antioksidan diperlukan untuk menangkal efek radikal bebas akibat polusi udara. Jeruk dan nanas merupakan sumber antioksidan. Penelitian dilakukan untuk mengetahui perbedaan pengaruh pemberian jeruk dengan nanas pada kadar MDA plasma subjek yang terpapar polusi gas buang kendaraan bermotor. Penelitian ini merupakan penelitian eksperimental terhadap 21 orang yang bekerja di Jalan Merdeka, berusia 20–40 tahun yang dibagi menjadi tiga kelompok yang dilakukan pada bulan Januari–Juli 2010. Kelompok pertama diberikan jeruk sebanyak 300 g selama 14 hari. Kelompok kedua diberikan nanas sebanyak 300 g selama 14 hari. Kelompok ketiga adalah kelompok kontrol. Kadar MDA plasma diukur sebelum dan setelah perlakuan. Data dianalisis dengan uji t berpasangan dan uji t tidak berpasangan. Hasil penelitian menunjukkan penurunan kadar MDA plasma setelah pemberian jeruk (1,42±0,29 vs 0,68±0,29) (p<0,05) dan setelah pemberian nanas (0,73±0,20 vs 0,40±0,13) (p<0,05). Penurunan kadar MDA plasma setelah pemberian jeruk lebih besar daripada nanas (0,74 ± 0,33 vs 0,24 ± 0,24) (p<0,05). Simpulan, jeruk lebih besar dalam menurunkan kadar MDA plasma pada subjek yang terpapar polusi gas buang kendaraan bermotor daripada nanas. [MKB. 2013;45(2):91–7]Kata kunci: Antioksidan, jeruk, malondialdehid plasma, nanas, polusi udara, radikal bebas The Effects of Orange and Pineapple Supplementation on Plasma Malondialdehyde Concentration in Subject Exposed to Air PollutionEnvironmental insults such as air polution from vehicle emission could increase generation of free radicals inside human body. A study conducted in December 2006 by the Department of Environmental Engineering Bandung Institute of Technology, revealed an increased tendency of air pollution production in certain areas in Bandung such as Jl. Merdeka where busy traffic frequently occurs. The amount of free radicals inside the body can be detected by measuring concentrations of plasma malondialdehyde (MDA). Antioxidants are needed to counteract the damaging effects of increased free radical formation due to air pollution insult. Pineapples and orange are antioxidant food sources. This study aims to find out the differences between orange and pineapple supplementation effects on plasma MDA concentration in subjects exposed to air pollution. The study is an experimental research concerning 21 subjects whom were working on Jl. Merdeka, page between 20--40 years old in January–July 2010. They were divided into three groups. The first group was given 300 grams of orange for 14 days. The second group was given 300 grams of pineapple for 14 days. The third group was the control group. Plasma MDA concentration was measured prior to and after the treatment. The data were analyzed using paired and independent t-test. The study revealed a lower plasma MDA concentration in subjects receiving orange (1.42±0.29 vs 0.68±0.29) (p<0.05) and in subjects receiving pineapple (0.73±0.20 vs0.40±0.13) (p<0.05). Plasma MDA concentration lowering effect of orange supplementation is greater than that of the pineapple supplementation (0.74±0.33 vs 0.24±0.24) (p<0.05). In conclusion, plasma MDA concentrationlowering effect of orange is greater than pineapple in subjects exposed to air pollution. [MKB. 2013;45(2):91–7]Key words: Air pollution, antioxidant, free radicals, orange, pineapple, plasma malondialdehyde DOI: http://dx.doi.org/10.15395/mkb.v45n2.90
Indeks Massa Tubuh Awal Kehamilan Ibu sebagai Indikator yang Paling Berperan terhadap Kenaikan Berat Badan Ibu Selama Hamil Zuhairini, Yenni; Kasmanto, Hendro; Nugraha, Gaga Irawan
Majalah Kedokteran Bandung Vol 48, No 3 (2016)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v48n3.847

Abstract

Berat bayi lahir rendah dipengaruhi oleh kenaikan berat badan ibu selama hamil. Penelitian ini bertujuan mencari indikator status gizi ibu trimester pertama yang paling berperan terhadap kenaikan berat badan ibu selama hamil. Kohort ini dilakukan selama tahun 2014 yang merupakan bagian dari Tanjungsari Cohort Study di Jawa barat. Variabel status gizi ibu trimester pertama (indeks massa tubuh (IMT), massa lemak (ML), massa lemak bebas (MLB), lingkar lengan atas (LLA)) dihubungkan dengan kenaikan berat badan (BB) ibu selama hamil dari trimester pertama sampai ketiga dengan analisis bivariat Pearson dilanjutkan dengan regresi linier multivariat. Perbedaan kenaikan berat badan ibu selama hamil pada tiap kelompok dengan uji ANOVA satu arah. Perubahan asupan energi dan protein diuji dengan uji T independen pada semua kelompok. Diperoleh 37 subjek yang telah mencapai trimester ketiga menunjukkan korelasi antara IMT, ML, MLB, LLA dengan kenaikan BB ibu selama hamil. Terdapat hubungan negatif IMT dengan KBB (p=0,002 dan r2=0,234). Kenaikan berat badan ibu selama hamil pada IMT kurang, normal, overweight, obes 1 dan obes 2 masing-masing 7,38; 8,54; 6,73; 4,38 dan 3,30 kg. Perubahan asupan energi dan protein pada subjek dengan IMT tinggi dan rendah masing-masing p=0,09 dan p=0,96. Simpulan, indeks massa tubuh ibu trimester pertama merupakan indikator yang paling berperan terhadap kenaikan berat badan ibu selama hamil, IMT berbanding terbalik dengan kenaikan berat badan ibu selama hamil kecuali pada IMT kurang. [MKB. 2016;48(3):171–5]Kata kunci: Ibu hamil, indeks massa tubuh, kenaikan berat badan Body Mass Index in Early Pregnancy as the Most Contributing Indicator for Weight Gain during Pregnancy Low birth weight is influenced by maternal weight gain during pregnancy. This study aimed to reveal the most contributing pre-pregnancy maternal nutritional status indicators pre-  that are responsible for maternal weight gain during pregnancy. This study  was carried out during the year of 2014  and was performed as a part of Tanjungsari Cohort Study in West Java. The pre-pregnancy maternal nutritional status variables (body mass index (BMI), fat mass (FM), fat free mass (FFM), and mid upper arm circumference (MUAC)) were associated with the gestational weight gain (GWG) of pregnant  women from  the  first  to the  third  trimester  using  Pearson  bivariate analysis followed by multivariate linear regression. The difference of GWG in each group was analyzed using one-way ANOVA test, while changes in energy and protein intake were tested using independent T test in all groups. From 37  subjects  who  had  reached  the  third  trimester, it was shown that there was a correlation of BMI, ML, MLB, and LLA to GWG. Themultivariate analysis showed a negative correlation between BMI and GWG (p=0.002 and r2=0.234). Maternal weight gain during pregnancy in underweight, normal weight, overweight, obese 1, and obese 2 women were 7.38, 8.54, 6.73, 4.38, and 3.30 kg, respectively, while changes in energy and protein intake in subjects with high and low BMI were p=0.09 and p=0.96, respectively. In conclusion, the pre-pregancy maternal body mass index is the most contributing indicator for maternal weight gain during pregnancy, BMI is inversely related to maternal weight gain during pregnancy, except in the underweight group. [MKB. 2016;48(3):171–5]Key words: Body mass index, gestational weight gain, pregnant women
Nutritional Status of Schizophrenic Patients Attending Outpatient Department of Psychiatry in Dr.Hasan Sadikin Hospital Maisyarah, Tiara Aulia; Nugraha, Gaga Irawan; Lidyana, Lynna
Althea Medical Journa Vol 1, No 1 (2014)
Publisher : Althea Medical Journa

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Background: Currently, schizophrenia is associated with many health problems due to weight changes caused by lifestyle changes and consumption of antipsychotic drugs (APDs). Nutritional status assessment is needed in order to lower the comorbidity through early detection of risk factors.Methods: This descriptive cross-sectional study involved 94 schizophrenic patients selected using consecutive sampling in October 2012 in Psychiatry Outpatient Department, Dr. Hasan Sadikin General Hospital, Bandung. An anthropometric measurement was verified (body mass index and waist circumference), physical activity level, type of antipsychotic drugs (APDs) used and duration of treatment acquired from medical records. Results: Among the subjects, 29.8% were 28–37 years old, with 69.1% males and 30.9% females. Most of them suffered from paranoid schizophrenia (71.3%). The body mass index (BMI) of 46.8% subjects were normal, 45.74% were overweight, whereas 7.45% were underweight. Male subjects mostly had smaller waist circumference (78%) compared to females who were dominantly above normal (52%). Physical activity levels were mostly sedentary (76%). Single typical APD were dominantly prescribed (46%). Subjects with normal BMI were mostly found among single typical APDs prescribers (53.5%), whereas the majority of atypical APDs users were overweight (61.9%). A total of 63% subjects had been prescribed APDs for 1–5 years, dominated by subjects with normal body mass index (78%). Conclusions: The majority of study subjects (46.8%) were found normal in terms of the body mass index. Male subjects mostly had normal waist circumference (78%) while females have a higher risk with measurement above normal as a more dominant finding (52%). [AMJ.2014;1(1):40–7]Keywords: Nutritional Status, Pscychiatry, SchizophreniaStatus Gizi Pasien Skizofrenia di Departemen Psikiatri Rumah Sakit Dr. Hasan Sadikin BandungLatar Belakang: Saat ini Skizofrenia merupakan suatu penyakit mental dengan komorbiditas yang tinggi akibat perubahan gaya hidup, faktor predisposisi, dan dampak mengonsumsi obat antipsikotik yang membuat penderita kerap mengalami perubahan berat badan. Oleh karena itu, diperlukan deteksi dini perubahan berat badan pada pasien skizofrenia sebagai pertimbangan penyusunan tatalaksana yang komprehensif.Metode: Studi deskriptif potong lintang ini dilakukan untuk mengetahui status gizi pasien skizofrenia di Klinik Rawat Jalan Departemen Psikiatri Sub Bagian Dewasa Rumah Sakit Dr. Hasan Sadikin Bandung. Pengukuran Indeks Massa Tubuh (IMT) dan lingkar pinggang dilakukan pada 94 pasien skizofrenia dewasa. Wawancara mengenai pekerjaan juga dilakukan untuk mengetahui tingkat aktifitas fisik, riwayat pengobatan responden didapatkan melalui rekam medis.Hasil: Dari 94 responden  (65 pria dan 29 wanita) mayoritas berusia 28–37 tahun (29.8%). Sebanyak 46.8% responden memiliki IMT normal, 45.74% responden adalah overweight, dan 7.45%  termasuk dalam kategori underweight. Responden  pria memiliki ukuran lingkar pinggang yang mayoritas normal (78%), sedangkan wanita sebagian besar memiliki ukuran lingkar pinggang di atas normal (52%). Tingkat aktifitas fisik responden rata-rata tergolong ringan (67%). Kebanyakan responden diberikan obat antipsikotik tipikal tunggal (46%) dan sebanyak 63% telah mengonsumsi obat antipsikotik selama 0–5 tahun. Simpulan:  Mayoritas   responden   memiliki  IMT  yang normal dengan  ukuran lingkar pinggang wanita lebih tinggi dibandingkan dengan pria.Kata Kunci: Status Gizi, Psikiatri, Skizofrenia
Enteric Pathogen Bacteria in Non-Broiler Chicken Egg Shells from Traditional Market and Supermarket, Jatinangor Subdistrict, West Java Arumugam, Kavita; Sudigdoadi, Sunarjati; Nugraha, Gaga Irawan
Althea Medical Journal Vol 2, No 3 (2015)
Publisher : Althea Medical Journal

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Background: Around 1.5 million of children dying annually due to diarrhea. Contaminated food is one of the sources of the diarrhea incidence (food borne diseases). Eggs are one of the least expensive forms of protein which is affordable by the community and is easily to find in either traditional or modern market/supermarkets.The objective of this study was to identify enteropathogenic bacteria contamination on non-broiler (ayam kampung) egg shell and to compare the findings between eggs sold in traditional and modern markets.Methods: This was a descriptive study performed at the Microbiology Laboratory of the Faculty of Medicine, Universitas Padjadjaran. A total of 40 eggs were used, 20 from two traditional markets and 20 from two modern markets. The eggs were swabbed using saline, dipped in tryptic soy broth and streaked on Mac Conkey agar. The collected data were analyzed and presented in tables.Results: Out of 40 samples, there were 19 positive cultures found from the traditional market and 16 from the modern market. There were 30 pink colonies indicating that they were lactose fermented, 5 transparent colonies indicated non-lactose fermentation, 4 showed no colony growth, and 1 grew an unidentified colony. The most found bacteria were Klebsiella sp. and Enterobacter sp. in both market. Conclusions: Eggs shells from traditional and modern markets are contaminated with Enteropathogenic microbes. DOI: 10.15850/amj.v2n3.487
Status gizi, asupan energi, dan serat sebagai faktor risiko kardiometabolik pada remaja pendek Fatimah, Siti Nur; Purba, Ambrosius; Rusmil, Kusnandi; Nugraha, Gaga Irawan
Jurnal Gizi Klinik Indonesia Vol 13, No 1 (2016): Juli
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, Fakultas Kedokteran UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.22682

Abstract

Background: Prevalence of stunted adolescents is important because related with the cardiometabolic risk factor. Control of risk factors reduces the comorbidity including body mass index (BMI) control. Improvement of environmental factors such as energy and fiber intake contribute to reducing disease risk. Objective: This study aimed to analyze the relationship of a stunted adolescent with BMI, energy and fiber intake. Method: This study used cross-sectional design. The subject consisted of early adolescents with 10 to 14 years old in Jatinangor district, West Java. Determination of short stature and BMI refers to the WHO Growth Chart 2005. Data collection by the measure of height, weight, BMI calculation, and interviewed food intake by 3x24 hour food recall and analyzed with Nutrisurvey program. Statistical analysis by Mann-Whitney U test. Results: A total of 212 participants (106 stunted and 106 non-stunted) were enrolled. The proportion of stunted girls is 58 (54,9%) and stunted boys 48 (45,1%). Average of BMI in stunted is 17,15 (2,59) kg/m2 and 18,38 (3,33) kg/m2 in non-stunted, energy intake is 1.488,83 (513,52)kcal in stunted and 1.704,32 (663,49) in non-stunted,  fiber intake is 4,36 (1,18) g in stunted and  4,53 (2,15) g in non stunted. There are significant differences in all variables between stunted and non-stunted with a p value for BMI 0,017, in energy intake 0,034 and fiber intake 0,032. BMI showed the correlation with disease risk. including cardiometabolic diseases in stunting. Energy intake and low fiber in growth age increase the risk of cardiometabolic diseases because in stunting have a low metabolic adaptation in protein synthesis and fat oxidation. Conclusion: The study shows there is a difference between BMI, energy intake and fiber in the stunted adolescent and non-stunted adolescent. Further research needs to analyze another risk fctor and intervention to improve nutrition status and metabolic condition.
Nutritional Status of Tetralogy of Fallot Patients at Dr. Hasan Sadikin General Hospital Bandung Cafrina, Gabriella; Firman, Armijn; Nugraha, Gaga Irawan
Althea Medical Journal Vol 3, No 2 (2016)
Publisher : Althea Medical Journal

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Background: Undernutrition is common in children with congenital heart disease (CHD), especially in developing countries including Indonesia. The objective of the study was to describe the nutritional status of children patients with Tetralogy of Fallot.Methods: This was a cross-sectional descriptive study using 41 medical records of children aged 0–14 years old with Tetralogy of Fallot that visited pediatric outpatient department of Dr. Hasan Sadikin General Hospital in period of January to December 2013. The variable was anthropometric measurement, namely weight-for-age, height-for-age, weight-for-height, and body mass index-for-age. These anthropometric data were analyzed using statistics software, WHO Anthro, and WHO AnthroPlus and were classified based on nutritional status according to WHO. The collected data were displayed in percentage.Results: There were more boys (60.98%) who had Tetralogy of Fallot compared to girls (39.02%). The percentage of undernutrition was 39.02% with 43.75% in 5–14 year old children. The percentage of stunting was 70.73% with 72% in 0–5 year old children. Meanwhile, the percentage of underweight was 52% in children aged 0–5 years old.Conclusions: The percentage of undernourished children with Tetralogy of Fallot is quiet high. Undernutrition occurs more often in 5–14 year old children, while stunting occurs more often in 0–5 year old children. [AMJ.2016;3(2):298–303]DOI: 10.15850/amj.v3n2.784
Nutritional Status of Hospitalized Stroke Patients: Assessment by Body Mass Index and Subjective Global Assessment Method Kartika, Gloria; Amalia, Lisda; Nugraha, Gaga Irawan
Althea Medical Journal Vol 4, No 2 (2017)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v4n2.1090

Abstract

Background: Stroke is a disease with a high mortality rate and common cause of disability. Nutritional factors are strongly associated with this disease. Malnutrition in hospitalized patients increases the incidence of complications, prolonged the length of stay and also the cost of hospitalization. Furthermore, nutritional status of stroke patients can deteriorate during hospitalization. The prevalence of malnutrition in hospitalized stroke patients is about 6% to 62%. The objective of this study was to identify  the nutritional status of hospitalized stroke patient.Methods: This was a descriptive cross-sectional study. Population of the study was hospitalized stroke patients at Neurology Ward, Kemuning Building Dr. Hasan Sadikin General Hospital Bandung, Indonesia from August until October 2014 who meet the inclusion criteria. Nutritional status was measured objectively using Body Mass Index (BMI) and subjectively using Subjective Global Assessment (SGA) method. The collected data were processed using  frequency tabulation and percentage.Results: Twenty six hospitalized stroke patients were included in this study. The hospitalized patients with normal BMI were about 12 people (46.15%), 8 people were overweight (30.77%), 4 people were undernourished (15.39%) and 2 people (7.69%) were obese. According to SGA measurement, approximately 18 people (69.22%) were moderately malnourished, and as much as 4 people (15.39%) were in good nutrition, whereas 4 people (15.39%) were severely malnourished.Conclusions: Majority of the hospitalized stroke patients has normal BMI and moderately malnourished based on SGA. DOI: 10.15850/amj.v4n2.1090
HUBUNGAN PENGUKURAN LEMAK SUBKUTAN DENGAN INDEKS MASSA TUBUH PADA LAKI-LAKI USIA LANJUT Fatimah, Siti Nur; Akbar, Leva B; Purba, Ambrosius; Tarawan, Vita Murniati; Nugraha, Gaga Irawan; Radhiyanti, Putri Tessa; Nurhayati, Titing
Jurnal Penelitian Gizi dan Makanan Vol 40, No 1 (2017)
Publisher : Pusat Penelitian dan Pengembangan Upaya Kesehatan Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/pgm.v40i1.6295.

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Degenerative diseases are associated with obesity. Body mass index (BMI) measurement is a way to measure disease risk,howeverfat mass more explain metabolic conditions associated with degenerative diseases. Research shows consistent relation between these two parameters with diseases risk. This study aims to determine the association of fat mass by skinfold thickness measurement with BMI. The study design was observational with cross-sectional approach. This research was done at the UniversitasPadjadjaran in 2015. The number of subjects were 96 men with the inclusion criteria over 50 years, exclusion criteria have abnormal posture and edema. Statistical analysis used Spearman rank correlation test and a simple linear regression. Characteristics of age 67.98 (SD: 9.81) years, height 1.61 (SD: 0.61) m, weight 66.67 (SD: 10.74) kg, BMI: 26.28 (SD 3,55) kg / m2, body fat: 30.98 percent. The distribution of nutritional status category: underweight 2 percent, normoweight 11.9 percent, overweight 27.27 percent, obese 58.4 percent. Fat mass category: normal category 41.6 percent and overfat 58.4 percent. Correlation between fat mass with age of 0.094 percent, with heights 0.14 percent and with a BMI 0.55 percent. Simple linier regression analysis shows the equation: percent fat mass = 2,757 + 0.089. This equation means every increase of 1 BMI will increase the fat mass percent by (2.757 + 1*0.089)2. The implications of this equation show that BMI can predict fat mass in elderly men based on subcutaneous fat thicknessmeasurements. Penyakit degeneratif berhubungan dengan faktor risiko obesitas. Pengukuran indeks massa tubuh (IMT) merupakan cara untuk mengukur risiko penyakit, tetapi massa lemak dapat menggambarkan kondisi metabolik yang berhubungan dengan penyakit degeneratif. Penelitian menunjukkan hubungan konsisten antara kedua parameter ini dengan risiko penyakit. Penelitian ini bertujuan untuk mengetahui hubungan antara massa lemak berdasarkan pengukuran tebal lemak subkutan dengan IMT. Disain penelitian adalah observasional dengan pendekatan potong lintang. Penelitian dilakukan di kampus Universitas Padjadjaran tahun 2015. Jumlah subjek 96 laki-laki dengan kriteria inklusi di atas 50 tahun, kriteria ekslusi  memiliki postur tubuh tidak normal dan edema. Variabel bebas adalah umur, tinggi badan dan IMT, variabel tergantung adalah massa lemak. Analisis statistik menggunakan uji korelasi Spearman rank dan uji regresi linier sederhana.Karakteristik usia 67,98(SD: 9,81) tahun, tinggi badan 1,61(SD : 0,61) m, berat badan 66,67 (SD : 10,74) kg, IMT: 26,28 (SD : 3,55) kg/m2, lemak tubuh: 30,98 persen.Sebaran kategori status giziterdiri dari berat badan kurang 2 persen, normal 11,9 persen, berat badan lebih 27,27 persen, obesitas 58,4 persen. Kategori massa lemak terdiri dari kategori normal 41,6 persen dan lebih 58,4 persen. Korelasi antara massa lemak dengan usia0,094 persen, dengan tinggi badan 0,14 persen dan dengan IMT 0,55 persen. Analisis regresi linier menghasilkan persamaan: persen massa lemak = 2,757 + 0.089 (IMT). Persamaan ini mempunyai arti setiap peningkatan 1 IMT akan meningkatkan persen massa lemak sebesar (2,757 + 1*0,089)2. Implikasi persamaan ini memperlihatkan IMT dapat memprediksi massa lemak pada laki-laki lanjut usia berdasarkan pengukuran tebal lemak subkutan.
Status gizi, asupan energi, dan serat sebagai faktor risiko kardiometabolik pada remaja pendek Fatimah, Siti Nur; Purba, Ambrosius; Rusmil, Kusnandi; Nugraha, Gaga Irawan
Jurnal Gizi Klinik Indonesia Vol 13, No 1 (2016): Juli
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, Fakultas Kedokteran UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.22682

Abstract

Background: Prevalence of stunted adolescents is important because related with the cardiometabolic risk factor. Control of risk factors reduces the comorbidity including body mass index (BMI) control. Improvement of environmental factors such as energy and fiber intake contribute to reducing disease risk. Objective: This study aimed to analyze the relationship of a stunted adolescent with BMI, energy and fiber intake. Method: This study used cross-sectional design. The subject consisted of early adolescents with 10 to 14 years old in Jatinangor district, West Java. Determination of short stature and BMI refers to the WHO Growth Chart 2005. Data collection by the measure of height, weight, BMI calculation, and interviewed food intake by 3x24 hour food recall and analyzed with Nutrisurvey program. Statistical analysis by Mann-Whitney U test. Results: A total of 212 participants (106 stunted and 106 non-stunted) were enrolled. The proportion of stunted girls is 58 (54,9%) and stunted boys 48 (45,1%). Average of BMI in stunted is 17,15 (2,59) kg/m2 and 18,38 (3,33) kg/m2 in non-stunted, energy intake is 1.488,83 (513,52)kcal in stunted and 1.704,32 (663,49) in non-stunted,  fiber intake is 4,36 (1,18) g in stunted and  4,53 (2,15) g in non stunted. There are significant differences in all variables between stunted and non-stunted with a p value for BMI 0,017, in energy intake 0,034 and fiber intake 0,032. BMI showed the correlation with disease risk. including cardiometabolic diseases in stunting. Energy intake and low fiber in growth age increase the risk of cardiometabolic diseases because in stunting have a low metabolic adaptation in protein synthesis and fat oxidation. Conclusion: The study shows there is a difference between BMI, energy intake and fiber in the stunted adolescent and non-stunted adolescent. Further research needs to analyze another risk fctor and intervention to improve nutrition status and metabolic condition.