Diah Kurnia Mirawati
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Hubungan antara Rentang Waktu Terjadinya Serangan Hingga Tiba di RSUD Dr. Moewardi dengan Prognosis Stroke Iskemik

Nexus Kedokteran Klinik Vol 1, No 2 (2012): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Stroke is the third leading cause of death in the world. The awareness of early signs and symptoms of stroke and referral to hospital efforts should be made because the successful treatment of stroke is determined by the speed of action in the acute phase (therapeutic window). In ischemic stroke, restoration or improvement of perfusion to the ischemic area is a therapy key. This study is aimed to determine the relationship between time range from stroke attack until arrive at the Dr. Moewardi hospital with ischemic stroke prognosis. Methods: This study was observational cohort analytic approach. A total of 48 subjects were selected by purposive sampling, they were ischemic stroke patients in the room Orchid II Dr. Moewardi Hospital. Data was collected by direct interview and examination of the patient by using NIHSS score. Data was analyzed by using multiple logistic regression models and processed with Statistical Product and Service Solutions (SPSS) for Windows 17.00. Results: Multiple logistic regression showed the results OR = 1.89;  CI 95% 0.395 – 9.035; and p=0.425. This result has controlled the confounding variables of age, blood pressure, blood sugar levels, and colesterol levels. Patient who arrived at the Dr. Moewardi hospital >24 hours after the stroke attack increases the risk of poor prognosis 1.890 times than that arrived at the hospital <6 hours and 6-24 hours. Conclusions: There is a moderate correlation between the time range from stroke attack until arrive at the Dr. Moewardi hospital with ischemic stroke prognosis, although in this study the relationship was not statistically significant. Keywords: time range, attack, Dr. Moewardi hospital, prognosis, ischemic stroke  

Hubungan Jenis Kelamin dengan Gangguan Kognitif Pasca Stroke Iskemik Serangan Pertama dengan Lesi Hemisfer Kiri

Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background: Stroke is a cerebrovascular disease which until now the third leading cause of death in the world. Stroke can cause physical disability to psychosocial disfunction, such as cognitive impairment. This study aimed to analyze the relationship between gender and cognitive impairment after ischemic stroke first attack with left hemisphere lesions. Methods: This type of research is an observational analytic with cross-sectional approach. Sample of this study were post ischemic stroke  patients with a total sample of 60 people. Measuring instrument used was Mini Mental State Examination (MMSE), and performed data analysis with multiple logistic regression analysis. Results: After the study on a sample of 60 post-stroke patients with a first ischemic attack left hemisphere lesions found post-stroke cognitive impairment in male patients amounted to 46.7%, whereas in female patients by 30%. The results of calculations using Binary Logistic Regression Analysis obtained OR = 0.14; CI 95% 0025 to 0794 and p = 0026. From these data showed statistically significant relationship between the gender with cognitive impairment after ischemic stroke first attack with left hemisphere lesions. Conclusions: There is a statistically significant relationship between gender to cognitive impairment on post-ischemic stroke patients. This conclusion is drawn after controlling for the effects of confounding factors such as age, level of education and cardiovascular risk factors: diabetes mellitus, hypertension, dyslipidemia. Keywords: gender, cognitive impairment, ischemic stroke

Hubungan Frekuensi Bangkitan dengan Skor Kualitas Hidup pada Penderita Epilepsi Umum di RSUD Dr. Moewardi

Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background: Epilepsy is a chronic neurology disease. When epilepsy was not well-controlled, it could cause so many effects such as decreasing quality of life score. The aim of this study was to find out the relation between seizure frequency and quality of life score of general epileptic patients in Dr. Moewardi hospital. Methods: This was an observational study with analytic cross-sectional approach conducted from July to August 2012 at Neurology Department of Dr. Moewardi hospital. Samples were taken by purposive sampling after selected based on inclusion and exclusion criteria. The frequency of seizure was recorded by medical record. The quality of life was assessed by QOLIE-31 questionnaire. Score of seizure frequency and quality of life were analyzed with one-way ANOVA models by SPSS 17.0 for Windows. Results: There were 30 samples consist of 13 women and 17 men. The average of quality of life total score in high seizure frequency was 59.56 ± 4.71, medium seizure frequency was 78.32 ± 2.20, and seizure free was 83.40 ± 2.34. There was a negative relationship between seizure frequency and quality of life score on patients with general epilepsy. Analysis by one-way ANOVA/Kruskal Wallis showed a statistically significant relationship (p < 0.05) for total score component and the other seven components. Conclusion: Patients with higher seizure frequency had lower quality of life score. Keywords: seizure frequency, quality of  life score, general epilepsy  

Hubungan antara Kecemasan dengan Frekuensi Bangkitan pada Penderita Epilepsi Parsial di RSUD Dr. Moewardi

Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background : Anxiety is a psychological disorder that involves dysregulation of the nervous system Therefore, anxiety could affected seizure’s threshold in people with epilepsy indirectly. The aim of this study was to know an association between anxiety and seizure frequency of partial epileptic patients in hospitals Dr. Moewardi. Methods: This was an observational study with analytic cross sectional approach. Samples were taken by purposive sampling after selected based on inclusion and exclusion criteria. The data were obtained by using of TMAS anxiety scale, interviewed seizures frequency in last one month, and the patients medical record. Analysis of anxiety and seizures frequency’s score used linear regression models by SPSS 17.0 for windows Results: There were 31 samples consisted of 10 women and 21 men. Result showed a significant positive relation between anxiety and seizure frequency of partial epileptic patients in hospitals Dr. Moewardi (p < 0.05, CI 95% = 0.06 - 0.037). Linear regression analysis test showed an equation that Y= a + bX = -1.174 + 0.218 X. It meaned that the seizure frequency would rise  -1.174 + 0.218 X unit for every inrcreasing of anxiety level. Conclusion: Patients with higher level of anxiety have had more often seizure attack. Keywords: Partial epileptic patients, anxiety, frequency of seizure