Articles

Found 15 Documents
Search

Factors Affecting the Development of Anxiety in Postmenopausal Women: A CrossSectional Study in Coastal Areas Saimin, Juminten; Wicaksono, Satrio; Junuda, Junuda; Minarti, Minarti
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 3 July 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Original Source | Check in Google Scholar | Full PDF (86.747 KB)

Abstract

  Objective: To analyze factors associated with anxiety in postmenopausal women.   Methods: This study was descriptive analytic with cross-sectional approach conducted in 228 postmenopausal women that aged 50-64 years old in coastal areas of Kendari City. Samples were taken by simple random sampling. The technique of collecting data used questionnaires and the Taylor Manifest Anxiety Scale (T-MAS). Data were analyzed using Chi-square test with a significance value p  0.05.   Results: The results showed that 188 respondents (82.4%) had. anxiety. Its most experienced anxiety was aged 50-54 years old (37.7%), low education (96.0%), as housewife (62.7%), low income (91.2%) and lived with a partner (54.4%). There was correlation between anxiety with age (p=0.016), education level (p = 0.009), income (p = 0.011), and residence status (p = 0.029). There was no correlation between anxiety with occupation (p = 0.351).   Conclusion: There was a correlation between anxiety in postmenopausal women in coastal areas with age, education level, income, and residence status.   Keywords: age, anxiety, education level, income, postmenopausal women, residence status
PENINGKATAN KEMAMPUAN GURU SEKOLAH DASAR DALAM MENGGUNAKAN MEDIA PEMBELAJARAN MELALUI KELOMPOK KERJA GURU DIDAERAH BINAAN III KECAMATAN GROGOL Minarti, Minarti
JURNAL PENELITIAN ILMU PENDIDIKAN JPIP, Vol 3, Nomor 1, Maret 2010
Publisher : JURNAL PENELITIAN ILMU PENDIDIKAN

Show Abstract | Original Source | Check in Google Scholar | Full PDF (1306.154 KB)

Abstract

The aims of this research are: to improve the ability of teachers in elementary school utility the study media through team teacher of working area guide III district Grogol school year 2009/2010,The research was conducted at state elementary school of area guide III district Grogol school year 2009/2010 The research was an action research. The research of action this entangle 7 elementary school. The teacher of class VI as sampel and headmaster assist in monitoring, The subjects of research were headmaster at that elementary school, the teacher of class VI as sampel and headmaster assist in monitoring. The collect of data were obtained by indepth interviewing, observation, discussion with the subjects of the research, the study of documents, and test. Meanwhile, data analysis using critical analysis technique and comparative-descriptive technique. The research was conducted in three cycles and the objectives of research was obtained successfully. The results of this action research were: to improve the ability of teachers utility the study media through team teacher of working in elementary school teacher area III district Grogol Sukoharjo, namely equal to 12,71%. Key Word: Ability of teacher, Team Teacher of Working, Utility of Media
Production of Lovastatin and Sulochrin by Aspergillus Terreus Using Solid State Fermentation Dewi, Rizna; Artanti, Nina; Mulyani, Hani; Lotulung, Puspa; Minarti, Minarti
Makara Journal of Technology Vol 15, No 1 (2011)
Publisher : Directorate of Research and Community Services, Universitas Indonesia

Show Abstract | Original Source | Check in Google Scholar | Full PDF (242.674 KB)

Abstract

Lovastatin is an anti-cholesterol agent that was produced by Aspergillus terreus using solid state fermentation (SSF). During this fermentation process, sulochrin is also produced as an unwanted co-metabolite. However, our previous result showed that sulochrin had potential as antidiabetes because it is an inhibitor agent of α-glucosidase. In this paper, we reported our observation on lovastatin and sulochrin production pattern in relation with inhibitor α-glucosidase activity during eleven days fermentation of A. terreus koji (SSF) ethyl acetate extract. Koji obtained from solid state fermentation with rice as the substrate and incubated at room temperature, sample is taken daily for eleven day (D-1 to D-11). Lovastatin and sulochrin production was measured by Liquid Chromatography- Mass Spectrometer based on their molecular weight m/z 404.5 and 332.3 respectively. The inibitory activity is measured by inhibition model of koji extract against α-glucosidase (EC 3.2.1.20) from Saccharomyces cereviceae. The results show that lovastatin production was started on the day 2 (0.04 mg/g) and achieving the optimal production on day 7 (11.46 mg/g), while sulochrin production was started on day 4 (0.60 mg/g) and keep produced until the end of fermentation period at Day 11 (3.11 mg/g). Koji extract was started to show inhibitory to α-glucosidase activity on Day 5 (IC50= 23.34 μg/mL) and keep showed activity until Day 11 (IC50=3.33 μg/mL). These results suggest that inhibitory activity of koji extract to α- glucosidase activity have relation with sulochrin biosynthesis production.
Adaptif Conservation (Acm) Model in Increasing Family Support and Compliance Treatment in Patient with Pulonary Tuberculosis in Surabaya City Region Kholifah, Siti Nur; Minarti, Minarti; Yumni, Hilmi
Jurnal Ners Vol 7, No 1 (2012): Vol 7 No. 1 April 2012
Publisher : Universitas Airlangga

Show Abstract | Original Source | Check in Google Scholar | Full PDF (179.839 KB)

Abstract

Introduction: Tuberculosis (TB) in Indonesia is still health problem and the prevalence rate is high. Discontinuing medication and lack of family support are the causalities. Numbers of strategies to overcome are seemingly not succeeded. Roles and responsibilities of family nursing are crucial to improve participation, motivation of individual, family and community in prevention, including pulmonary tuberculosis. Unfortunately, models of pulmonary tuberculosis currently unavailable. The combination of adaptation and conservation in complementarily improving family support and compliance in medication is introduced in this study. Method: This research intended to analyze Adaptive Conservation Model (ACM) in extending family support and treatment compliance. Modeling steps including model analysis, expert validation, field trial, implementation and recommending the output model. Research subject involves 15 families who implement family Assistance and supervision in Medication (ASM) and other 15 families with ACM. Result: The study revealed ACM is better than ASM on the case of family support and medication compliances. It supports the role of environment as influential factor on individual health belief, values and decision making. Therefore, it is advised to apply ACM in enhancing family support and compliance of pulmonary TB patients. Discussion: Social and family supports to ACM group obtained by developing interaction through communication. Family interaction necessary to improve family support to pulmonary tuberculosis patients. And social support plays as motivator to maintain compliance on medication
Sintesis N-Oktilsinamamid dan Aktivitasnya terhadap Sitotoksik Sel Kanker Leukemia P388 Ernawati, Teni; Nurhalimah, Neneng; Minarti, Minarti
Jurnal Kimia Valensi Jurnal Kimia VALENSI Volume 3, No. 2, November 2017
Publisher : Department of Chemistry Faculty of Sciences and Technology UIN Jakarta

Show Abstract | Original Source | Check in Google Scholar | Full PDF (730.546 KB)

Abstract

Sintesis senyawa N-Oktilsinnamamid yang diturunkan dari senyawa metil trans-sinamat dengan menggunakan katalis basa telah dilakukan. Senyawa metil sinamat terlebih dahulu dikonversi menjadi asam sinamat melalui reaksi hidrolisis dengan basa menghasilkan asam sinamat. Selanjutnya asam sinamat diamidasi dengan menggunakan oktilamin dan 1,3 disikloheksilkarboodiimide (DCC) dan 4-dimetilaminopiridin (DMAP) sebagai katalis. Dari penelitian ini diperoleh rendemen hasil sintesis asam sinamat, sintesis N-Oktilsinnamami yang cukup baik. Hasil reaksi diidentifikasi dengan menggunakan 1H-NMR, 13C-NMR dan LC-MS. Uji sitotoksik senyawa N-Oktilsinamamid terhadap sel leukemia P388 diperoleh nilai IC50=6.71 µg/mL. Synthesis of N-Octylcinnamamide compound derived from methyl trans-cinnamate using abase catalyst has been done. First, The compound of methyl trans-cinnamate was converted into cinnamic acid by hydrolysis reaction with an alkaline condition. Furthermore cinnamic acid was amidated by using octylamine and 1,3 dicyclohexylcarbodiimide (DCC) and 4-dimethylaminopyridine (DMAP) as a catalyst. The results of this study were obtained synthesis of cinnamic and synthesis of N-Octylcinnamamide are good enough. Identification of this product was using by 1H-NMR, 13C-NMR and LC-MS.  Cytotoxic test of N-Octylcinnamamide against P388 leukemia cell was obtained IC50=6.71µg/mL.
Isolation and Identification of Antiplasmodial Compound from Methanol Extract of Calophyllum bicolor P. F. Steven Abbas, Jamilah; Hanafi, Muhammad; Artanti, Nina; Sundowo, Andini; Minarti, Minarti; Asih, Puji Budi Setia; Syafrudin, Din
ANNALES BOGORIENSES Vol 19, No 2 (2015): Annales Bogorienses
Publisher : Research Center for Biotechnology - Indonesian Institute of Sciences (LIPI)

Show Abstract | Original Source | Check in Google Scholar | Full PDF (742.591 KB)

Abstract

Calophyllum bicolor (Clusiacea) is a big tree from Indonesian rain forest in Palangkaraya, Central Kalimantan. Calophyllum or bintagor is one of many sources of natural bioactive compounds that can be used in the fields of health and pharmaceuticals. The aim of this research was to explore the antiplasmodial activity of methanol extract of Calophyllum bicolor P.F. Steven against Plasmodium falciparum. The methanol extract was purified by colomn chromatography system, hexane – ethyl acetate was used as solvent with increasing polarity. One pure compound was obtained and was elucidated based on the 1H-&13C-NMR and 2D-NMR, [COSY, HMBC and HMQC] data and the isolated compound was identified as xanthone. Methanol extract showed antiplasmodial activity growth inhibition against P. falciparum with IC50 5.2 ppm and the new 5-methoxy trapezifolixanthone compound have maximum inhibition at concentration 0.11 nMol.
Factors Affecting the Development of Anxiety in Postmenopausal Women: A CrossSectional Study in Coastal Areas Saimin, Juminten; Wicaksono, Satrio; Junuda, Junuda; Minarti, Minarti
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 3 July 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Original Source | Check in Google Scholar | Full PDF (86.747 KB)

Abstract

  Objective: To analyze factors associated with anxiety in postmenopausal women.   Methods: This study was descriptive analytic with cross-sectional approach conducted in 228 postmenopausal women that aged 50-64 years old in coastal areas of Kendari City. Samples were taken by simple random sampling. The technique of collecting data used questionnaires and the Taylor Manifest Anxiety Scale (T-MAS). Data were analyzed using Chi-square test with a significance value p  0.05.   Results: The results showed that 188 respondents (82.4%) had. anxiety. Its most experienced anxiety was aged 50-54 years old (37.7%), low education (96.0%), as housewife (62.7%), low income (91.2%) and lived with a partner (54.4%). There was correlation between anxiety with age (p=0.016), education level (p = 0.009), income (p = 0.011), and residence status (p = 0.029). There was no correlation between anxiety with occupation (p = 0.351).   Conclusion: There was a correlation between anxiety in postmenopausal women in coastal areas with age, education level, income, and residence status.   Keywords: age, anxiety, education level, income, postmenopausal women, residence status
PENGARUH KOMPOSISI HERBAL DALAM MINUMAN TEH HIJAU GAMBUNG HERBAL TERHADAP HAMBATAN α-GLUKOSIDASE Megawati, Megawati; Mulyani, Hani; Minarti, Minarti; Ernawati, Teni; Darmawan, Akhmad
Jurnal Ilmiah As-Syifaa Vol 10, No 2 (2018): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Original Source | Check in Google Scholar | Full PDF (650.017 KB)

Abstract

The aim of this study is to make a formula of green tea that is enriched by other herbs. Green tea drinks are made using the basic ingredients of gambung (THG) green tea enriched with sapodilla leaves (Manilkara zapota (Aw) bay leaves (Syzygium polyanthum (Am), Artocarpus communis (Un) breadfruit leaves, and cinnamon leaves (Cinnamomum verum (K)). The composition of gambung herbal green tea is made by reference to the antidiabetic activity of each herb. All the samples were tested for inhibition of α-glucosidase enzymes and toxicity using the lethality test method for brine shrimp. All samples showed good inhibition of the α-glucosidase enzyme barriers of gamboeng green tea (THG) 82.05%, sapodilla leaves (Aw) 97.81%, breadfruit leaves (Un) 73.34%, bay leaves (Am) 93.80%, cinnamon leaves (K) 91.24 %. The inhibition value of α-glucoside enzymes in the formulation of gamboeng herbal green tea drinks: 96.203% (GKUn) is higher when compared to the GKAm formula (94.78%) and GKAw (62.487%).
HUBUNGAN PENGETAHUAN DAN DUKUNGAN KELUARGA DENGAN PEMBERIAN IMUNISASI MEASLES RUBELLA Aprilia, Rosa; Satya, Satya; Minarti, Minarti
Jurnal 'Aisyiyah Medika Vol 4, No 2 (2019): Jurnal 'Aisyiyah Medika
Publisher : Jurnal 'Aisyiyah Medika

Show Abstract | Original Source | Check in Google Scholar | Full PDF (567.625 KB)

Abstract

Latar belakang: Saat ini di Indonesia masih ada anak-anak yang belum mendapatkan imunisasi secara lengkap bahkan tidak pernah mendapatkan imunisasi sedari lahir. Hal itu menyebabkan mereka mudah tertular penyakit berbahaya karena tidak adanya kekebalan terhadap penyakit tersebut. Kementerian Kesehatan (Kemenkes) mengubah konsep imunisasi dasar lengkap menjadi imunisasi rutin lengkap. Imunisasi rutin lengkap itu terdiri dari imunisasi dasar dan lanjutan. Imunisasi dasar saja tidak cukup, diperlukan imunisasi lanjutan untuk mempertahankan tingkat kekebalan yang optimal (Kementerian Kesehatan RI, 2019). Tujuan: Mengetahui hubungan pengetahuan dan dukungan keluarga dengan pemberian imunisasi Measles Rubella. Metode: Jenis penelitian ini bersifat survey analitik dengan pendekatan cross sectional. Penelitian dilaksanakan di Puskesmas Taman Bacaan Tahun 2019. Analisa data yang digunakan adalah analisa data chi square. Hasil: Dengan 70 responden hasil penelitian didapat bahwa ada hubungan penegetahuan ibu dengan pemberian imunisasi measles rubella p value 0.006 ada hubungan dukungan keluarga dengan p value  0.000. Saran: kepada Pimpinan puskesmas harus meningkatkan partisipasi dalam memberikan sosialisasi dan penyuluhan tentang imunisasi MR. Sehingga sosialisasi dapat disampaikan secara merata kepada seluruh ibu-ibu yang memilikik anak-anak.Kata Kunci : Imunisasi MR, Pengetahuan Dan Dukungan Keluarga
HYPNOTHERAPY DECREASES STRESS IN ELDERLY HYPERTENSION Kastubi, Kastubi; Minarti, Minarti; Saudah, Noer
INTERNATIONAL JOURNAL OF NURSING AND MIDWIFERY SCIENCE (IJNMS) Vol 1 No 1 (2017): IJNMS Volume 1 Issue 1, Agustus 2017
Publisher : Bina Sehat Press. Departement Research and Community Engagement Bina Sehat PPNI Institute of Health Science, Indonesia

Show Abstract | Original Source | Check in Google Scholar | Full PDF (309.233 KB)

Abstract

Stress stimulates the sympathetic nervous encouraging the heart and cause an increasing blood pressure. Efforts to reduce hypertension pharmacological and non-pharmacological. Non-pharmacological experiment of which is hypnosis. The research objective was to analyze the decrease of stress to elderly hypertensive therapy with hypnotherapy. The research design used experimental pretest - Posttest with Control Group. The population were all the elderly with hypertension in the elderly health care center PacarKeling , and Kemayoran Surabaya with 35 elderlies. Number of sample 15 intervention group, 15 control group. The sampling technique used Simple Random Sampling. Variable intervention was therapeutic applications of hypnosis to elderly hypertensive. The dependent variable was the stress in elderly hypertensive. The statistical test used paired t-test. It showed changes in stress to the control group -7.33, while the experminent group amounted to 14.60. Results can reduce stress in the group treated with hypnotherapy an average decrease of 14.6. Results showed that there were differences in the level of stress control and experiment groups with significant value of p = 0.000 (p <0.05), The effect of hypnotherapy was also shown in the systolic blood pressure change between control and experiment groups showed a mean difference of ranks. In the control group 20.8, while in the experimental group 10.2. Mann Whitney test results obtained by the significant value of p = 0.000 (p <0.05) in mean systolic blood pressure differences between control and experiment groups. Hypnotherapy can reduce stress and blood pressure in the experiment group. Causes of stress on the individual such as physical pain, and the outside factor could be due to family problems, economic. Suggestions that hypnosis can be used as a new experiment method stress problem in the elderly