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Potensi Jarak Pagar (Jatropha curcas) sebagai Larvasida Hayati Pencegah Penyakit Demam Berdarah Dengue Iswantin, Dyah; Riyadhi, Adi; Kesumawati, Upik; Rosman, Rosihan; Mangunwidjaja, Djumali; Rahminiwati, Min
Jurnal Ilmu Pertanian Indonesia Vol 16, No 1 (2011): Jurnal Ilmu Pertanian Indonesia
Publisher : Institut Pertanian Bogor

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Abstract

Recently, Indonesia has big problem caused by dengue haemorraghic fever with A. aegypti as vector. Potential medicine and vaccine for curing this disease have not been found. The effective method to prevent this disease is the use of A. aegypti larvicidal. The chemical larvicidal has disadvantage for evironmental aspect. To solve this problem, the biological larvicidal has a good chance to develop. Indonesia has megadiversity which can be developed as biological larvicidal. Crude aqueous extracts and ethanol extracts of Jatropha curcas (Jarak pagar) seed and oil of Jatropha curcas were evaluated for larvicidal potential against the Aedes aegypti mosquito. Among all extracts, Jatropha curcas oil possessed a highest activity against the 3th instar larvae of Aedes. LC50 values of Jatropha curcas oil was 1507 ppm for 24 h and 866 ppm for 48 h. It was suggested that the Croton tiglium oil and Jatropha curcas oil possess larvicidal properties that could be developed and used as biological larvicidal. Keywords: Jatropha curcas, oil, Aedes aegypti, biological larvicidal, dengue  haemorraghic fever. 
Studi agrobiofisik kamandrah (croton tiglium L.) dan penentuan potensi awal kamandrah sebagai larvasida hayati pencegah penyakit demam berdarah dengue Iswantini, Dyah; Rosman, Rosihan; Kesumawati, Upik; Mangunwidjaja, Djumali; Rahminiwati, Min; Riyadhi, Adi
Jurnal Ilmu Pertanian Indonesia Vol 14, No 2 (2009): Jurnal Ilmu Pertanian Indonesia
Publisher : Institut Pertanian Bogor

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Abstract

The aim of the research is to obtain the ecological condition and propagation of kamandrah (Croton tiglium L.) and determination of its potency as biological larvacidal for preventing dengue haemorraghic fever. Agrobiophysic study indicated that Croton tiglium L. plant need full sunlight(> 70 %). low intensity of sunlight could decrease the ability of plant to produce seed. The plant could grow well on podzolic land (30-50 m upon sea surface). Seed of kamandrah from Ampah has growth percentage of 43.8 °/o, height of 27.5 em, stem diameter of 5 em, total leaves of 10, and total primary branches of 2. Phytochemical assay resulted that among other part of Kamandrah, Kamandrah seed has highest alkaloid content. Because alkaloid compound has high larvicidal activity, kamandrah seed has high potency as larvicide. Among all of extracts of part of plant, oil of Croton tiglium L. has the highest potency as biological larvacidal with 863.67 ppm of LC50 for 24 hours of treatment.Keywords : Kamandrah (Croton tiglium L.), biological larvacidal, Dengue Haemorraghic fever, agrobiphysicstudy.
Ability of Lactobacillus plantarum JR64 isolated from noni juice in lowering Cholesterol in vivo Sumarno, Lanjar; Mangunwidjaja, Djumali; M. Fauzi, Anas; Syamsu, Khaswar; Siswi Indrasti, Nastiti; Prasetya, Bambang
International Journal of Science and Engineering (IJSE) Vol 2, No 1 (2011)
Publisher : Chemical Engineering Diponegoro University

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Abstract

Recently public’s attention to the importance of healthy food increases rapidly. Probiotic based food exploiting lactic acid bacteria is among the healthy food. Lactobacillus plantarum JR64 isolate from Morinda citrifolia fruit was assessed for its probiotic in-vivo by using Wistar  Rat. The purpose of this research was to study the ability of probiotic Lactobacillus plantarum JR64 in lowering serum LDL (Low Density Lipoprotein) of Wistar Rat. Twenty Rats were grouped into 4, each group consisted of 5 Rats. First Group was a negative control  given standard normal diet of 20 gr/day plus aquadest. Second Grup was a positive control given cholesterol normal diet 20 gr /day plus Propil Tio Urasil (PTU) 60 mg/kg body weight/day. Third Group was supplemented with normal diet 20 gr /day plus Propil Tio Urasil (PTU) 60 mg  kg body weight /day and  1012 CFU Lactobacillus plantarum JR64. Fourth Group was the same as third Group unless the probiotic using commercial probiotic Lactobacillus bulgariccus at 1012 CFU. Blood samples were withdrawn for measurement of total cholesterol, triglyceride, High Density Lipoprotein (HDL), and Low Density Lipoprotein (LDL) cholesterol every week and measured by using spectrophotometer with 546 nanometers wavelength. The results show that probiotic Lactobacillus plantarum JR64 isolated from noni juice significantly (p < 0,01) reduce Low Density Lipoprotein (LDL) and Triglyceride in vivo  and tend to reduce High Density Lipoprotein (HDL) and total cholesterol.
Isolation and Fermentation of Lactobacillus plantarum JR64 as an Omega 6 Probiotic Producer Sumarno, Lanjar; Mangunwidjaja, Djumali; M. Fauzi, Anas; Syamsu, Khaswar; Siswi Indrasti, Nastiti; Prasetya, Bambang
International Journal of Science and Engineering (IJSE) Vol 2, No 2 (2011)
Publisher : Chemical Engineering Diponegoro University

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Abstract

Application of lactic acid probiotic bacteria in health food diversification currently is progressing rapidly.  It is encouraged the study of searching the potential strains from local resources (Ponorogo Residence) namely noni fruits (badeg pace) and noni wine.  Aims of this study were to perform the isolation, identification, and production of  probiotic Lactobacillus sp. JR64 fermentation process as a producer of Omega-6 (ω-6) lowering cholesterol and design of probiotic creamy product.   Beginning stages of research was strains isolating and in-vitro testing, the best result were used in  molecular  identification technology development for the production of metabolites through the manipulation of environmental variation  of glucose 20 g / l, 30 g / l and 40 g / l that influenced the substrate concentration of linoleic acid productivity. The result of new isolates isolation showed that isolates that obtained from noni wine, Lactobacillus plantarum JR64, was potential as probiotic condidate.   The effieciency of fermentation  substrates using  Yx/s and Yp /s  in the exponential phase was the highest value for the fermentation of 24 hours of  Yx/ s; 17.03% and Y p/s; 74.72%, while the results of design and the best formulation for viability cells of lactobacillus  plantarum probiotics JR64 was composed of 15 g and 50g butter 15 g icing sugar as well as during storage of the refrigerant temperature was 8.92 x 108 CFU / ml.  [Key Words : Omega-6,  Lactobacillus plantarum JR64, fermentation]
Adsorpsi Surfaktan Nonionik Alkil Poliglikosida pada Antar muka Fluida-Fluida Adisalamun, Adisalamun; Mangunwidjaja, Djumali; Suryani, Ani; Sunarti, Titi Candra; Arkeman, Yandra
Jurnal Rekayasa Kimia & Lingkungan Vol 9, No 1 (2012): Jurnal Rekayasa Kimia & Lingkungan
Publisher : Chemical Engineering Department, Syiah Kuala University, Banda Aceh, Indonesia

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Abstract

Nonionic surfactants have been used extensively in various industrial applications such as cleaning, personal care, crop protection, paint and coating, textile finishing, emulsion stabilization, food and leather processing. In this study, we have studied the adsorption of three nonionic surfactants of alkyl polyglycoside, namely commercial APG from Cognis and APG produced from glucose as well as APG synthesized from sago starch, at fluid–fluid interfaces. The variation of surface and interfacial tension with the concentration of surfactant in the bulk was studied, and the data were fitted using a surface equation of state derived from the Langmuir isotherm. The agreement between ?(c) data and Langmuir isotherm model was very good.Keywords: adsorption, air/water interface, interfacial tension, surface tension
In-situ Alkaline Transesterification of Jatropha curcas seed Oil for Production of Biodiesel and Nontoxic Jatropha seed Cake Nazir, Novizar; Mangunwidjaja, Djumali; Setyaningsih, Dwi; Yuliani, Sri; Yarmo, Mohd. Ambar; Salimon, Jumat; Ramli, Nazaruddin
International Journal on Advanced Science, Engineering and Information Technology Vol 4, No 1 (2014)
Publisher : International Journal on Advanced Science, Engineering and Information Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (652.297 KB) | DOI: 10.18517/ijaseit.4.1.353

Abstract

The production of fatty acid methyl ester (FAME) by direct in situ alkaline-catalyzed transesterification of the triglycerides (TG) in Jatropha curcas seeds was examined. The experimental results showed that the amount of Jatropha curcas seed oil dissolved in methanol was approximately 83% of the total oil and the conversion of this oil could achieve 98% under the following conditions: less than 2% moisture content in Jatropha curcas seed flours, 0.3–0.335 mm particle size, 0.08 mol/L NaOH concentration in methanol, 171:1 methanol/oil mole ratio, 45.66 oC reaction temperature and 3.02 h reaction time. The use of alkaline methanol as extraction and reaction solvent, which would be useful for extraction oil and phorbol esters, would reduce the phorbol esters content in the Jatropha curcas seed cake. The cake after in-situ transesterification is rich in protein and is a potential source of livestock feed. Further, the the toxicity studies were also investigated on male rate by feeding the seed cake after after in-situ transesterification as well as the from solvent and mechanical extraction. Food intake, growth rate, protein efficiency ratio (PER) and transformation index (TI) showed that the meal is potential as protein supplement to livestock feed.
Potensi Jarak Pagar (Jatropha curcas) sebagai Larvasida Hayati Pencegah Penyakit Demam Berdarah Dengue Iswantini, Dyah; Riyadhi, Adi; Kesumawati, Upik; Rosman, Rosihan; Mangunwidjaja, Djumali; Rahminiwati, Min
Jurnal Ilmu Pertanian Indonesia Vol 16, No 1 (2011): Jurnal Ilmu Pertanian Indonesia
Publisher : Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Recently, Indonesia has big problem caused by dengue haemorraghic fever with A. aegypti as vector. Potential medicine and vaccine for curing this disease have not been found. The effective method to prevent this disease is the use of A. aegypti larvicidal. The chemical larvicidal has disadvantage for evironmental aspect. To solve this problem, the biological larvicidal has a good chance to develop. Indonesia has megadiversity which can be developed as biological larvicidal. Crude aqueous extracts and ethanol extracts of Jatropha curcas (Jarak pagar) seed and oil of Jatropha curcas were evaluated for larvicidal potential against the Aedes aegypti mosquito. Among all extracts, Jatropha curcas oil possessed a highest activity against the 3th instar larvae of Aedes. LC50 values of Jatropha curcas oil was 1507 ppm for 24 h and 866 ppm for 48 h. It was suggested that the Croton tiglium oil and Jatropha curcas oil possess larvicidal properties that could be developed and used as biological larvicidal. 
Studi agrobiofisik kamandrah (croton tiglium L.) dan penentuan potensi awal kamandrah sebagai larvasida hayati pencegah penyakit demam berdarah dengue Iswantini, Dyah; Rosman, Rosihan; Kesumawati, Upik; Mangunwidjaja, Djumali; Rahminiwati, Min; Riyadhi, Adi
Jurnal Ilmu Pertanian Indonesia Vol 14, No 2 (2009): Jurnal Ilmu Pertanian Indonesia
Publisher : Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The aim of the research is to obtain the ecological condition and propagation of kamandrah (Croton tiglium L.) and determination of its potency as biological larvacidal for preventing dengue haemorraghic fever. Agrobiophysic study indicated that Croton tiglium L. plant need full sunlight(> 70 %). low intensity of sunlight could decrease the ability of plant to produce seed. The plant could grow well on podzolic land (30-50 m upon sea surface). Seed of kamandrah from Ampah has growth percentage of 43.8 °/o, height of 27.5 em, stem diameter of 5 em, total leaves of 10, and total primary branches of 2. Phytochemical assay resulted that among other part of Kamandrah, Kamandrah seed has highest alkaloid content. Because alkaloid compound has high larvicidal activity, kamandrah seed has high potency as larvicide. Among all of extracts of part of plant, oil of Croton tiglium L. has the highest potency as biological larvacidal with 863.67 ppm of LC50 for 24 hours of treatment.
KAJIAN FINANSIAL ISOLASI CITRONELLAL DAN RHODINOL PADA INDUSTRI BERBASIS SENYAWA TURUNAN MINYAK SEREH WANGI Endah Lestari, Retno Sri; Mangunwidjaja, Djumali; Suryani, Ani; Fauzi, Anas Miftah; Rusli, Meika Syahbana
Jurnal Teknotan Vol 6, No 2 (2012)
Publisher : Jurnal Teknotan

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Abstract

Isolasi komponen Citronellal dan Rhodinol pada minyak sereh wangi dapat diterapkan pada industri untuk meningkatkan nilai tambah dan mengembangkan industri intermediate minyak sereh wangi. Untuk mengetahui kelayakan penerapannya, diperlukan analisis finansial terhadap proses isolasi tersebut. Kelayakan investasi pada pendirian industri baru maupun pengembangan industri minyak sereh dilihat NPV, BEP, PBP, Net B/C dan IRR yang dapat menggambarkan apakah proyek masih atraktif untuk direalisasikan. Pada pendirian industri baru, nilai NPV sebesar Rp11,844,269,430.12, IRR sebesar  47 %. Masa pengembalian modal (PBP) tercapai selama periode 2.79 tahun. Nilai Net B/C adalah 2.75 dan titik impas produksi (BEP) diperoleh pada nilai penjualan Rp. 5,217,742,676.09. Sedangkan pada pengembangan industri minyak sereh wangi, NPV dari pengembangan industri tersebut sebesar Rp 12.348.032.363,16. Nilai IRR untuk pengembangan industri dengan  Input 600 kg / proses  adalah 89 %. Masa pengembalian  modal (PBP) pengembangan industri tercapai selama periode 4,41 tahun. Nilai Net B/C yang diperoleh dari pendirian Pabrik Citronellal dan Rhodinol  ini adalah 6,30. Titik impas produksi (BEP) diperoleh pada nilai penjualan Citronellal sebesar Rp 20.912.029.225,35. Hal ini menunjukkan bahwa pendirian industri baru maupun pengembangan industri minyak sereh wangi yang sudah ada, layak untuk direalisasikan. Kata kunci: minyak sereh wangi, Citronellal, Rhodinol, kelayakan finansial, industri
Application of Microwave Heating in Biomass Hydrolysis and Pretreatment for Ethanol Production Hermiati, Euis; Mangunwidjaja, Djumali; Sunarti, Ttiti C; Suparno, Ono; Prasetya, Bambang
ANNALES BOGORIENSES Vol 14, No 1 (2010): Annales Bogorienses
Publisher : Research Center for Biotechnology - Indonesian Institute of Sciences (LIPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (505.18 KB) | DOI: 10.1234/33

Abstract

Recently, due to depletion of  fossil derived energy stock in the world, there are growing  interests in utilizing biomass sources of bioethanol. There are basically two types of biomass that are usually used or converted to ethanol, starchy and lignocellulosic biomass. The conversion of starchy and lignocellulosic materials are widely explored,  however,  there  are  still  some  drawbacks,  such  as  high  enzyme  cost  and  intensive  energy  needed. Therefore, lower cost as well as energy and time efficient process technology in biomass conversion to ethanol  is important in enhancing the use of biomass to substitute fossil fuel. Microwave heating offers some advantages to overcome these drawbacks, especially due to its quick heat transfer and its heating selectivity. In conventional heating the  heat  was  transferred  through  conduction  or  convection  process  which  took  longer  time.  Thus,  by using microwave, degradation of starchy and lignocellulosic biomass could be completed in shorter time than by using conventional heating method. The roles of microwave heating in the degradation of biomass, especially starchy and lignocellulosic biomass  and its relation to the hydrolysis and pretreatment of that particular biomass for ethanol production are reviewed and discussed.   Keywords: biomass, pretreatment, ethanol, microwave