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Perbedaan Asupan Nutrisi Makanan dan Indeks Massa Tubuh (IMT) antara Perokok Aktif dan Non-perokok pada Usia Dewasa Suryadinata, Rivan V.; Lorensia, Amelia; Sari, Rika K.
Indonesian Journal of Clinical Pharmacy Vol 6, No 3 (2017)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (565.981 KB) | DOI: 10.15416/ijcp.2017.6.3.171

Abstract

Rokok merupakan salah satu ancaman terbesar bagi kesehatan masyarakat di dunia, dan perokok cenderung memiliki indeks massa tubuh (IMT) lebih rendah dan penurunan status gizi yang dapat meningkatkan risiko malnutrisi yang makin memperburuk kondisi kesehatan perokok dibandingkan dengan non-perokok. Tujuan penelitian ini adalah mengetahui perbedaan asupan nutrisi makanan terkait kalori perhari dan indeks massa tubuh (IMT) antara perokok aktif dan non-perokok. Penelitian ini menggunakan metode cross-sectional dengan pengumpulan responden menggunakan purposive sampling. Variabel-variabel yang akan diukur dalam penelitian ini meliputi: asupan nutrisi makanan dengan metode recall 24 jam dan IMT. Sampel penelitian ini adalah perokok aktif dan non-perokok usia dewasa di Surabaya pada bulan November 2015 hingga Januari 2016. Penelitian ini melibatkan 110 responden yang terdiri dari 55 perokok aktif dan 55 non-perokok, dengan sebaran data usia dan jenis kelamin yang homogen di antara kedua kelompok. Hasil uji perbedaan menunjukkan bahwa tidak terdapat perbedaan antara asupan nutrisi perokok aktif dengan non-perokok dengan Sig. 0,972 (p>0,05), dan tidak terdapat perbedaan antara IMT perokok aktif dengan non-perokok asupan nutrisi dengan nilai Sig. 0,745 (p>0,05). Oleh karena itu, disimpulkan bahwa tidak ada perbedaan asupan nutrisi dan IMT antara perokok aktif dan non-perokok.Kata kunci: Asupan nutrisi, indeks massa tubuh (IMT), perokok Differences in Nutrition Food Intake and Body Mass Index between Smoker and Non-smoker in AdultSmoking is one of the greatest threats to public health in the world, and smokers tend to have a lower body mass index (BMI) and the decline in nutritional status that can increase the risk of malnutrition which worsen the health condition of smokers compared to non-smokers. The purpose of this study was to determine differences in nutrition-related food calories per day and body mass index (BMI) between active smokers and non-smokers. This study used cross-sectional with a collection of respondents using purposive sampling. The variables measured in this study includes nutritional intake of food with a 24-hour recall method and IMT. Samples were active smokers and non-smokers adulthood in Surabaya from November 2015 until January 2016. Results of research on the use of 110 respondents consisting of 55 active smokers and 55 non-smokers, with a distribution of data for age and sex homogeneous between the two groups. The test results show that the difference there were no differences between the nutritional intake of active smokers and non‑smokers with Sig. 0.972 (p>0.05), and there is no difference between BMI active smokers and non‑smokers for nutrients intake by the Sig. 0.745 (p>0.05). It was therefore concluded that there is no nutritional intake and BMI between active smokers and non-smokers.Keywords: Body mass index (BMI), nutrition, smoker
Drug-related problems and clinical risk factors relationship in hepatic cirrhosis patients Lorensia, Amelia; ., Widyati; Hubeis, Aziz; Bagijo, Hary
INDONESIAN JOURNAL OF PHARMACY Vol 22 No 3, 2011
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (190.249 KB) | DOI: 10.14499/indonesianjpharm0iss0pp223-228

Abstract

Diffusion  processes  in  hepatic  cirrhosis  is  characterized  with  fibrosis  and structural changed. Patients with cirrhosis are at risk to get problems because of the  effects  of  the  drugs  used  have  drug-related  problems  (DRPs),  due  to changes  in  heart  function  that  affects  many  aspects of  drug  pharmacokinetics. Therefore,  treatment  of  patient  with  hepatic  cirrhosis  should  consider  the  drug and  dose  adjustment  so  that  subsequent  problems  could  be  avoided.  The research  method  was  prospective  and  descriptive,  with  a  purposive  sampling technique.  Patients’s  treatment  were  monitoring  and analyzed.  Significance  of 0000  means  that  p  (0000)  <0.05,  then  the  Pearson  correlation  test  results  are H1a, ie there was a relationship between the numberof DRPs events by the total number of clinical risk factors of DRPs in patientswith cirrhosis. Therefore from this relationship could be expected to know the possible risk of DRPs in patients. The  increasing  number  of  clinical  risk  factors  DRPs in  patients  with  cirrhosis, indicate  thatthe  patient  should  receive  a  more  stringent  monitoring  of  the provision of therapy because the risk of experiencing DRPs more.Key words: cirrhosis, drug related problems (DRPs), clinical risk factors of DRPs
Cost-Effectiveness Analysis of Pharmacotherapy for Hematemesis-Melena Treatment in Hospitalized Patients with Hepatic Cirrhosis de Queljoe, Doddy; Lorensia, Amelia; Widharta, Liana; Widjaja, Sugiarto
The Indonesian Biomedical Journal Vol 5, No 1 (2013)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v5i1.50

Abstract

BACKGROUND: Acute variceal haemorrhage is a complication of cirrhosis that can be life threatening. It is a pharmacist’s duty to ensure therapeutic and pharmaceutical care which is not only safe and effective for the patient but also is cost-effective in order to attain improvement of the patient’s quality of life. Therefore, pharmacoeconomic evaluation especially cost-effectiveness analysis (CEA), which compares costs and consequences of drug therapy, is needed. This study was aimed to evaluate the therapeutic cost-effectiveness of hematemesis-melena treatment in hepatic cirrhotic patients.METHODS: A total of 42 patients receiving vitamin K and vitamin K-transamin were studied retrospectively from patients’ medical records in 2 years and analyzed with cost-effectiveness grid and average cost-effectiveness ratio (ACER) based on Child-Turcotte-Pugh (CTP) Score.RESULTS: Cost-effectiveness grid was dominant for vitamin K in patients with CTP Score A. ACER analysis showed a lower score for vitamin K in all patients included CTP Score classification. There was no significant difference in duration of cessation of bleeding treatment in patients with vitamin K compared with vitamin K-transamin in patients with CTP Score A and B, while significant difference was found in patients with CTP Score C.CONCLUSION: Vitamin K appeared to be more cost effective as compared with vitamin K-transamin in all patients. The use of vitamin K had greater benefit than the combination with transamin in all patients and CTP Score classification, and thus should be considered as a primary therapy. Therefore, transamin addition as an alternative therapy for hepatic cirrhosis patients with hematemesis-melena should be considered.KEYWORDS: CEA, cost-effectiveness analysis, child-turcotte-pugh score, hepatic cirrhosis, hematemesismelena, vitamin K, transamin
Keamanan Penggunaan Aminofilin pada Pengobatan Asma di Rumah Sakit Delta Surya Sidoarjo Lorensia, Amelia; Wahjuningsih, Endang; Supriadi, Supriadi
Indonesian Journal of Clinical Pharmacy Vol 1, No 4 (2012)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (663.323 KB)

Abstract

Aminofilin adalah obat yang umum digunakan untuk mengobati asma di Indonesia dan merupakan obat dengan rentang terapi sempit. Meskipun harganya terjangkau, data tentang keamanan penggunaan aminofilin masih kurang. Penelitian ini bertujuan untuk menganalisis keamanan aminofilin berdasarkan terjadinya Adverse Drug Reaction (ADR) pada pasien rawat inap di rumah sakit. Penelitian ini menggunakan desain retrospektif untuk data pasien di rumah sakit selama 2 tahun. Sampel dikumpulkan dengan menggunakan metode purposive sampling yang menggunakan aminofilin dalam terapi asma. ADR yang terjadi dicatat dan dianalisis berdasarkan literatur, kemudian dievaluasi dengan Naranjo Scale yang merupakan alat untuk mengidentifikasi kemungkinan ADR terkait obat. Pasien yang terlibat dalam penelitian ini adalah 41 orang yang menggunakan aminofilin untuk pengobatan eksaserbasi asma. Ditemukan satu kasus yang diduga kemungkinan ADR obat yang terjadi dalam penelitian ini, yaitu hipertensi dengan takikardi. Secara umum semua gejala asma pada pasien rawat inap membaik. Penelitian ini menunjukkan bahwa aminofilin aman digunakan untuk pengobatan asma meskipun hanya terdapat satu insiden diduga ADR yang direkam selama pengamatan. Hal tersebut masih perlu diamati untuk melihat kemungkinan terjadinya ADR. Observasi dari hasil laboratorium, wawancara dengan pasien dan tenaga kesehatan lain dibutuhkan untuk penelitian lebih lanjut.Kata kunci: Keamanan, asma, pasien rawat inap Safety of Aminophylline for Asthma Therapy in Delta Surya Hospital at SidoarjoAbstractAminophylline is common used for treating asthma in Indonesia and has narrow therapeutic index. Despite of its affordable price, data on the safety of using aminophylline is still poorly documented. The aims of this study is to analyze the safety of using aminophylline based on Adverse Drug Reaction (ADR) in hospitalized patients. This study used retrospective design by collecting 2-years-data of hospitalized patients. Using purposive sampling methods, samples were collected from patients who received aminophylline for asthma therapy. ADR event were recorded and evaluated based on some literatures. It was evaluated by Naranjo Scale, a common tool to identify the probability of ADR related drug. From 41 patients who used aminophylline for their exacerbation in asthma treatment, there was one suspected incident of ADR events related to hypertension with tachycardia. In general, aminophyllinewould improve symptoms in hospitalized patients with asthma. This study demonstrates that aminophyllineis safe although there was only one suspected incident of ADR which could be recorded during these observations. However, for further research it still requires observation from laboratory tests and communication with patients and other healthcare workers.Key words: Safety, asthma, hospitalized patients
PROFIL VITAMIN D PADA PASIEN ASMA DAN NON-ASMA DEWASA DI SURABAYA Suryadinata, Rivan Virlando; Lorensia, Amelia; Aprilia, Anugrah Putri
The Indonesian Journal of Public Health Vol 12, No 1 (2017): The Indonesian Journal Of Public Health
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (295.274 KB) | DOI: 10.20473/ijph.v12i1.2017.106-117

Abstract

Asthma is a chronic inflammatory disease on respiratory tract, where airflow are retricted dan chronic inflammation result in bronchial epithelium damage. Pathogenesis mechanism of asthma is influenced by vitamin D as an immunomodulator. The low vitamin D levels can trigger asthmaexacerbations. The study aimed to determine the levels of vitamin D from blood sample in astmatic young adult in compared to non astmatics, to identify the risk of vitamin D deficiency, that can aggravate asthma symptoms. The study used an observational analytic cross sectional design. Subjects were chosenthrough a purposive sampling method. Population was young adults in Surabaya. Subjects were 26 asthmatic patientsdan 26 non-asthmatic young adult in South Surabaya that fulfilled inclusion dan exclusion criteria. The study was conducted in May 2015 to July 2016. The results showed vitamin Dlevels in the asthma group 24.5 ± 2.95 while in the non-asthma group 20.52 ± 2.47. All respondents in both groups had vitamin D levels > 30 ng/mL (normal value), dan there was significant difference between levels of vitamin D in asthma dan non-asthma patients (p < 0.05). Therefore, increasing knowledge about the importance of vitamin D should be done, because it can change behavior through lifestyle, diet dan physical activity in the community.Keywords: asthma, vitamin D
Efektivitas dan Risiko Toksisitas Aminofilin Intravena pada Pengobatan Awal Serangan Asma Lorensia, Amelia; Ikawati, Zullies; Andayani, Tri M.; Suryadinata, Rivan V.; Hantoro, Khaula A. A.; Firanita, Lisma D.
Indonesian Journal of Clinical Pharmacy Vol 7, No 2 (2018)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (455.651 KB) | DOI: 10.15416/ijcp.2018.7.2.78

Abstract

Asma merupakan penyakit inflamasi kronis pada saluran pernafasan yang mempunyai prevalensi global yang cukup besar. Perburukan penyakit asma berupa serangan asma yang menyebabkan peningkatan gejala asma dan penurunan fungsi paru secara progresif. Salah satu obat asma yang masih sering digunakan di Indonesia adalah aminofilin intravena. Aminofilin merupakan obat dengan rentang terapi sempit yang berisiko menyebabkan toksisitas obat, namun data perbandingan keuntungan efektivitas dan keamanan obat tersebut belum memadai. Penelitian ini bertujuan untuk mengetahui efektivitas aminofilin intravena pada pengobatan awal serangan asma berupa perbaikan gejala asma dan kejadian toksisitas terkait gejala yang muncul dan kadar teofilin dalam darah di suatu rumah sakit di Surabaya, Indonesia. Penelitian ini menggunakan metode pra-eksperimental yang dilaksanakan sejak 2014 hingga 2016. Sebanyak 27 pasien terlibat dalam penelitian ini. Terapi yang diberikan adalah aminofilin intravena selama satu jam. Metode sampling yang digunakan adalah consecutive sampling dengan teknik analisis deskriptif dan jum. Semua subjek penelitian menunjukkan perbaikan gejala serangan asma dengan terapi aminofilin intravena selama satu jam, dan tidak ada yang mengalami toksisitas karena kadar teofilin dalam darah di bawah rentang terapi. Aminofilin masih efektif dalam mengurangi gejala pada serangan asma dan tidak menunjukkan risiko toksisitas.Kata kunci: Aminofilin, efektivitas, serangan asma, toksisitas Effectiveness and Toxicity Risk of Intravenous Aminophylline in Exacerbation Asthma TreatmentAbstractAsthma is a chronic inflammatory disease in the respiratory tract that has a considerable global prevalence. The worsening of asthma is an asthma attack that causes asthma symptoms to increase and decreased lung function progressively. One of the most commonly used asthma medications in Indonesia is intravenous aminophylline. Aminophylline is a drug with a narrow range of therapies that is at risk of causing drug toxicity, but the comparative data on the efficacy and safety benefits of the drug are inadequate. This study aimed to determine the effectiveness of aminophylline intravenously in the early treatment of asthma attacks in the form of improvements in asthma symptoms and toxicity events related to the symptoms that appear and blood theophylline levels in a hospital in Surabaya, Indonesia. This study used a pre-experimental method which was carried out from 2014 to 2016. A total of twenty seven patients were involved in the study. The therapy given was aminophylline intravenously for one hour. The sampling method used was consecutive sampling with descriptive analysis technique. All subjects showed improved symptoms of asthma attacks with intravenous aminophylline therapy for one hour, and none had toxicity due to theophylline levels in the blood below the therapeutic range. Aminophylline is still effective in reducing symptoms in asthma attacks and does not indicate the risk of toxicity.Keywords: Aminophylline, asthma attack, effectiveness, toxicity
Analisis Kejadian Leukositosis Pasca Terapi Aminofilin Intravena Dibandingkan dengan Salbutamol Nebulasi pada Pasien Eksaserbasi Asma Lorensia, Amelia; Ikawati, Zullies; Andayani, Tri M.; Maranatha, Daniel; Wahjudi, Mariana
Indonesian Journal of Clinical Pharmacy Vol 5, No 3 (2016)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (320.986 KB) | DOI: 10.15416/ijcp.2016.5.3.149

Abstract

Salbutamol adalah terapi lini pertama untuk mengatasi gejala eksaserbasi asma. Aminofilin sudah tidak digunakan karena merupakan obat rentang terapi sempit yang sering menimbulkan adverse drug reaction (ADR). Kedua terapi tersebut dapat menimbulkan peningkatan kadar leukosit terkait ADR yang dapat memengaruhi terapi lain. Penelitian ini bertujuan membandingkan kejadian leukositosis antara terapi salbutamol nebulasi yang merupakan terapi lini pertama dengan aminofilin intravena yang sering digunakan di beberapa tempat untuk terapi eksaserbasi asma. Metode yang digunakan adalah kuasi eksperimental dengan pengukuran profil leukosit darah sebelum dan sesudah intervensi. Penelitian ini dilaksanakan pada bulan Januari 2014–Juni 2015 di beberapa rumah sakit di Surabaya, Indonesia. Kejadian leukositosis terkait ADR pada kelompok aminofilin (n=2) dengan nilai skala naranjo sebesar 6 poin yang kemungkinan besar merupakan ADR. Perubahan profil darah yang terjadi pada kedua pasien hanya pada kadar leukosit saja sedangkan data darah lainnya normal. Oleh karena itu, profil darah pada penggunaan kedua terapi dalam eksaserbasi asma perlu dipantau secara berkesinambungan agar tidak memengaruhi rekomendasi penambahan terapi lainnya.Kata kunci: Aminofilin, eksaserbasi asma, leukositosis, salbutamolPost-Therapy Leukocytosis Events After Intravenous Aminophylline Compared to the Nebulized Salbutamol in Asthma Exacerbations Patients Salbutamol known as the first-line therapy for asthma exacerbations symptoms relieving. Aminophylline are now no longer used because of its narrow therapeutic range of drugs and frequently provoking adverse drug reaction (ADR). Both of these therapies can lead to ADR-related leukocytes level increasing that interfere the concurrent therapies. This study was aimed to compare the state of leukocytosis after therapy with salbutamol nebulizer therapy as the first-line therapy with intravenous aminophylline for the treatment of asthma exacerbations. Quasi experimental method was used in this study, with blood leukocytes profile measure before and after the intervention body temperature measurement as data supplement. This research was conducted in January 2014–June 2015 at several hospitals in Surabaya, Indonesia. The incidence of ADRs associated leukocytes in aminophylline group (n=2) with a value scale naranjo by 6 points, most likely ADR. Significant difference found only in leukocyte level in two patient. More biomarkers profiles should be monitored assording to concurrent therapies for asthma exacerbation.Keywords: Aminophyiline, asthma exacerbation, leukocytosis, salbutamol
Studi Pendahuluan Polimorfisme Genetik Gen CYP1A2*1F pada Pasien Asma dan Nonasma di Indonesia Queljoe, Doddy de; Wahjudi, Mariana; Erdiansyah, Muhammad; Suryadinata, Rivan V.; Lorensia, Amelia
Indonesian Journal of Clinical Pharmacy Vol 4, No 1 (2015)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (322.933 KB) | DOI: 10.15416/ijcp.2015.4.1.8

Abstract

Polimorfisme genetik CYP1A2 berkaitan dengan metabolisme teofilin sehingga dapat memengaruhi kadar obat dalam darah serta berpengaruh terhadap kejadian adverse drug reaction (ADR) dan outcome klinis terapi asma. Frekuensi polimorfisme CYP1A2 diketahui bervariasi antar etnis. Diduga populasi Indonesia memiliki frekuensi varian gen CYP1A2*1F yang tinggi. Penelitian ini bertujuan untuk mengetahui profil polimorfisme gen CYP1A2*1F pada sampel nonasma dan asma di Indonesia dengan populasi lain berdasarkan literatur. Pengambilan data dilakukan pada Januari–Juni 2014. Sampel darah diperoleh dari 29 orang nonasma dan 16 pasien asma. Setelah dilakukan ekstraksi DNA genomik kemudian ditentukan polimorfisme gen CYP1A2*1F dengan metode PCR-RFLP. Hasil penelitian ini menunjukkan bahwa polimorfisme gen CYP1A2*1F pada sampel nonasma adalah 10,35% (3/29) untuk C/C, 37,93% (11/29) untuk C/A dan 51,72% (15/29) untuk A/A. Pada penderita asma frekuensi distribusi genotip C/A sebesar 81,25% (13/16) dan A/A sebesar 18,75% (3/16). Tidak terdapat perbedaan signifikan (p=0,276) frekuensi alel antara sampel nonasma dan pasien asma. Frekuensi gen CYP1A2*1F pada populasi  Indonesia lebih besar dibandingkan dengan populasi Mesir, Jepang, dan Inggris akan tetapi lebih rendah dibandingkan dengan Malaysia. Oleh karena itu, dapat disimpulkan tidak terdapat perbedaan frekuensi.Kata kunci: Asma, CYP1A2*1F, polimorfisme genetikPilot Study on Genetic Polymorphisms CYP1A2*1F on Asthma Patients and Nonasthma in IndonesiaGenetic polymorphisms of CYP1A2 is related to the theophylline metabolism that may affect drug levels in the blood, which can also affect incidence of adverse drug reaction (ADR) and clinical outcomes of asthma therapy. The frequency of CYP1A2 polymorphism is known to vary among ethnic. Allegedly the Indonesian population has high frequency of gene variants of CYP1A2*1F. This study aims to determine the profile of CYP1A2*1F gene polymorphism in a sample of nonasthma and asthma in Indonesia with other populations based on the literature. Data were taken on January–June 2014. Blood samples were obtained from 29 nonasthma samples and 16 patients with asthma. After extraction of genomic DNA, CYP1A2*1F gene polymorphisms determined by PCR-RFLP. The results of this study indicate that the CYP1A2*1F gene polymorphism in nonasthma samples was 10.35% (3/29) for C/C, 37.93% (11/29) for the C/A, and 51.72% (15/29) for A/A. The asthmatics genotype have a frequency distribution of C/A genotype of 81.25% (13/16) and A/A of 18.75% (3/16). There was no significant difference (p=0.276) allele frequencies between samples of nonasthma and asthma patients. The frequency of CYP1A2*1F gene in Indonesian population is higher than the population of Egypt, Japan, and UK, but lower compared to Malaysia. It can be concluded that there is no difference in frequency.Keywords: Asthma, CYP1A2*1F, genetic polymorphisms
Asupan Vitamin C dan E Dengan SQ-FFQ terhadap Fungsi Paru Perokok dan Non-Perokok Pratiwi, Siska Rian; Lorensia, Amelia; Suryadinata, Rivan Virlando
Media Kesehatan Masyarakat Indonesia Vol 14, No 2: JUNI 2018
Publisher : Faculty Of Public Health, Hasanuddin University, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (282.111 KB) | DOI: 10.30597/mkmi.v14i2.3998

Abstract

Asap rokok merupakan salah satu sumber radikal bebas eksogen yang dapat menyebabkan kerusakan sel yang mengakibatkan penurunan fungsi paru. Vitamin C dan E merupakan antioksidan yang dapat menghambat aktivitas senyawa oksidan. Tujuan dari penelitian ini adalah mengetahui perbedaan kondisi fungsi paru, asupan vitamin C, asupan vitamin E pada perokok aktif dan non perokok, serta pengaruh asupan Vitamin C dan E terhadap kondisi fungsi paru. Desain penelitian yang digunakan adalah case control. Variabel yang diukur meliputi asupan vitamin C dan E dengan semi quantitative-food frequency questionnaire (SQ-FFQ) serta kondisi fungsi paru dengan handheld spirometer. Sampel penelitian ini terdiri dari 63 sampel perokok dan 63 sampel non perokok. Hasil uji menunjukkan fungsi paru pada perokok dan non perokok berbeda signifikan (p=0,00). Asupan vitamin C (p=0,00) dan E (p=0,029) pada perokok aktif dan non perokok juga menunjukkan hasil yang berbeda signifikan.Hasil analisis menunjukkan adanya pengaruh asupan vitamin C (r=0,63) dan vitamin E (r=0,22) terhadap kondisi fungsi paru. Terdapat perbedaan asupan vitamin C,E, dan fungsi paru pada perokok dan non perokok, serta adanya pengaruh asupan vitamin C dan E terhadap fungsi paru.
PHYSICAL ACTIVITY AND VITAMIN D LEVEL IN ASTHMA AND NON-ASTHMA AKTIVITAS FISIK DAN KADAR VITAMIN D PADA PASIEN ASMA DAN NON-ASMA Lorensia, Amelia; Suryadinata, Rivan Virlando; Saputra, Rifaldi
Jurnal Farmasi Indonesia Vol 11, No 1 (2019)
Publisher : Indonesian Research Gateway

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfi.v11i1.591

Abstract

Worsen asthma symptoms is associated with low vitamin D levels that increases asthma attacks risk. Physical activity is one factor that affects vitamin D levels in the blood. This study aimed to identify relationship physical activities effects with vitamin d levels on asthma and non-asthma patients. The study was conducted in March-June 2018. The subjects were asthma patients and non-asthma adults and didn’t have other comorbidities. Data analysis used pearson test to determine physical activity effect with vitamin D levels. There were significant differences in vitamin D levels (P &lt;0.000) and physical activity (P &lt;0.000) in asthma and non asthma respondents. The results of the correlation test between vitamin D levels and physical activity in Approximate Significance value was 0.965, which means there were very strong relationships between vitamin levels and physical activity on the respondents of asthma and non asthma. So, the asthma patients with sufficient physical activity will have normal vitamin D levels to improve control of asthma symptoms. Worsen asthma symptoms is associated with low vitamin D levels that increases asthma attacks risk. Physical activity is one factor that affects vitamin D levels in the blood. This study aimed to identify relationship physical activities effects with vitamin d levels on asthma and non-asthma patients. The study was conducted in March-June 2018. The subjects were asthma patients and non-asthma adults and didn’t have other comorbidities. Data analysis used pearson test to determine physical activity effect with vitamin D levels. There were significant differences in vitamin D levels (P &lt;0.000) and physical activity (P &lt;0.000) in asthma and non asthma respondents. The results of the correlation test between vitamin D levels and physical activity in Approximate Significance value was 0.965, which means there were very strong relationships between vitamin levels and physical activity on the respondents of asthma and non asthma. So, the asthma patients with sufficient physical activity will have normal vitamin D levels to improve control of asthma symptoms.