I. Lesmana
Department of Pharmacy, Faculty of Mathematics and Sciences, Udayana University, Bali-Indonesia

Published : 3 Documents
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DIFFERENCES OF TUMOR MASSES AND HEMOGLOBIN LEVELS IN CERVICAL CANCER SQUAMOUS CELL TYPE PATIENTS TREATED WITH COMBINATION OF PACLITAXEL AND CARBOPLATIN CHEMOTHERAPY Noviyani, R.; Suwiyoga, K.; Lesmana, I.; Niruri, R.; Tunas, K.; Budiana, and I N. K.
BALI MEDICAL JOURNAL Vol 3, No 1 (2014)
Publisher : BALI MEDICAL JOURNAL

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Abstract

Background: Paclitaxel and carboplatin are standard operating procedure for chemotherapy treatment of cervical cancer squamous cell carcinoma at Sanglah General Hospital, Bali-Indonesia. Chemotherapy improves outcome of cancer treatment. However, chemotherapy brings also a variety of adverse effects and complications. This study aims to evaluate the therapeutic and adverse effects of chemotherapy in patients with squamous cell cervical cancer. Methods: This is a case study of six patients with cervical cancer underwent chemotherapy paclitaxel and carboplatin 3-series at Sanglah General Hospital, Bali-Indonesia during January to November 2013. The therapeutic effect of chemotherapy was assessed from cervical cancer tumor mass measured before and after chemotherapy 3-series. The adverse effect of chemotherapy was determined from hemoglobin levels measured before and after chemotherapy. Data were analyzed using a paired t-test with a level of confidence of 95% using the SPSS to find out the differences. Results: In this study we found that there is a difference between tumor mass pre and post 3 series chemotherapy within p < 0.05. In term of toxic effect, we also obtained that there were difference of hemoglobin between pre and post of treatment within p < 0.05. Conclusion: Paclitaxel carboplatin as a chemotherapy drug in patients with cervical cancer is highly recomended when seen from the effects of reduced tumor size, and has a low side effect of anemia (anemia grade 1).
Phenotypic characteristics of Exotic-broiler, Kampung, Male Exotic-layer, KUB-1 and Pelung chickens Saragih, Hendry Tri; Viniwidihastuti, F.; Lembayu, R. P.; Kinanthi, A. R.; Kurnianto, H.; Lesmana, I.
Jurnal Ilmu Ternak dan Veteriner Vol 24, No 1 (2019): MARCH 2019
Publisher : Indonesian Center for Animal Research and Development (ICARD)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14334/jitv.v24i1.1889

Abstract

The needs for chicken meat have been dominated by meat from exotic broilers (bred from imported parent). The potential of local broilers chicken in Indonesia is expected to be able to provide the meat for national needs for chicken meat. The objective of this research was to determine the day-old-chick (DOC) phenotypic characteristics of chickens in Indonesia that have the potential as broilers. The phenotypic characteristics are in the form of body morphometry, visceral organ weight and small intestinal histo-morphology. The chickens used were the DOC type of exotic Broiler, Kampung, exotic male Layer, KUB-1 and Pelung. A total of 125 chickens consisting of 25 chickens of each strain at posthatched age were observed for its body morphometry and its visceral organ weight, and small intestinal histo-morphology. The observed data were then analyzed by similarity analysis using MVSP 3.22 to create a dendogram with the Unweighted Pair Group with Aritmetic Average (UPGMA) method. Results showed that there were 2 different clusters from the level of similarity in their characteristics. Exotic broilers had 94.65% similarity to male exotic layer chicken and 92.26% to pelung chicken, while Kampung chickens had 90.16% similarity to KUB-1Chicken. In conclusion, it is indicated that the level of similarity of the phenotypic characteristics of pelung chickens were close to the type of exotic broiler and male exotic layer chicken. This level of similarity lead  to the expectation that pelung chickens potential to be a candidate for meat-type of local chicken.
Phenotypic characteristics of Exotic-broiler, Kampung, Male Exotic-layer, KUB-1 and Pelung chickens Saragih, Hendry Tri; Viniwidihastuti, F.; Lembayu, R. P.; Kinanthi, A. R.; Kurnianto, H.; Lesmana, I.
Jurnal Ilmu Ternak dan Veteriner Vol 24, No 1 (2019): MARCH 2019
Publisher : Indonesian Center for Animal Research and Development (ICARD)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (531.394 KB) | DOI: 10.14334/jitv.v24i1.1889

Abstract

The needs for chicken meat have been dominated by meat from exotic broilers (bred from imported parent). The potential of local broilers chicken in Indonesia is expected to be able to provide the meat for national needs for chicken meat. The objective of this research was to determine the day-old-chick (DOC) phenotypic characteristics of chickens in Indonesia that have the potential as broilers. The phenotypic characteristics are in the form of body morphometry, visceral organ weight and small intestinal histo-morphology. The chickens used were the DOC type of exotic Broiler, Kampung, exotic male Layer, KUB-1 and Pelung. A total of 125 chickens consisting of 25 chickens of each strain at posthatched age were observed for its body morphometry and its visceral organ weight, and small intestinal histo-morphology. The observed data were then analyzed by similarity analysis using MVSP 3.22 to create a dendogram with the Unweighted Pair Group with Aritmetic Average (UPGMA) method. Results showed that there were 2 different clusters from the level of similarity in their characteristics. Exotic broilers had 94.65% similarity to male exotic layer chicken and 92.26% to pelung chicken, while Kampung chickens had 90.16% similarity to KUB-1Chicken. In conclusion, it is indicated that the level of similarity of the phenotypic characteristics of pelung chickens were close to the type of exotic broiler and male exotic layer chicken. This level of similarity lead  to the expectation that pelung chickens potential to be a candidate for meat-type of local chicken.