Nani Kurniani
Department of Pharmacology and Therapy Faculty of Medicine Universitas Padjadjaran

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Characteristics of Patient with Brachial Plexus Injury in Neurophysiology Laboratory of Dr. Hasan Sadikin General Hospital Bandung, Indonesia, from 2003 to 2012 Kurnianto, Ivan; Kurniani, Nani; Soenggono, Arifin
Althea Medical Journal Vol 2, No 3 (2015)
Publisher : Althea Medical Journal

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Background: Brachial plexus is a network of nerves that controls the upper limb. Unfortunately, it can be injured easily which is called brachial plexus injury (BPI). It can cause disability. Until now, the epidemiology of BPI in Indonesia is still lacking. The aim of this study was to describe the characteristics of patients with BPI in Bandung, in order to increase knowledge and attention of health care provider and community to prevent BPI.Methods: This was a descriptive retrospective study. Data from medical records of patients with BPI who underwent electromyography (EMG) in Neurophysiology Laboratory Dr. Hasan Sadikin General Hospital, Bandung from 2003 to 2012 were collected. The data included age, sex, mode of injury, affected side and distribution of paralysis. Collected data were presented as percentages shown in tables.Results:  A total of 91 cases were collected during study period, which consisted of 69 males and 22 females (76% vs. 24%). Most of them were in productive age group (11−20 years and 21−30 years). The main cause of brachial plexus injury was traffic accident (76%), followed by birth injury. Distribution of paralysis was mostly in postganglionic area of cervical (C)5, C6, C7, C8 and thoracal (T)1 (67%). Around two third of the cases involved the right side of upper limb.Conclusions: The study showed that most of patients with BPI are male in their productive ages. Traffic accident is the most common cause, and the most affected side is the right side of upper limb. DOI: 10.15850/amj.v2n3.529
Correlation between Body Mass Index and Disability in Patient with Chronic Low Back Pain Teck, Tiang Soon; Prabowo, Tertianto; Kurniani, Nani
Althea Medical Journal Vol 3, No 4 (2016)
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Abstract

Background: Low back pain is discomfort presented below the margin of the 12th thoracic rib and above the inferior gluteal fold with or without leg pain. It is also a major cause of disability. Several risk factors have been identified for contributing low back pain. It is important to determine whether body mass index (BMI) can affect the disability in patients with chronic low back pain. Oswestry disability index (ODI) questionnaire has been used to measure the severity of disability. Thus, the focus of study was to determine correlation between BMI and disability in patients with chronic low back pain. Methods: Sixty two patients aged 18 years old or more who were clinically diagnosed as having low back pain at least 3 months participated in this study in the period of October to November 2015 in the Department of Physical Medicine and Rehabilitation of Dr. Hasan Sadikin General Hospital Bandung. Total sampling method was used. Gender, age, weight, height, BMI and disability were recorded using ODI questionnaire. This analytical study was cross sectional study and the ordinal variable was analyzed using linear regression analysis.Results: Females had higher proportion (77). Chronic low back pain patients were equally distributed on normal weight and overweight categories. Patient with chronic low back pain had higher chances of developing moderate disability. There were positive correlation between BMI and disability. Nevertheless, there was no statistically analysis difference between model 1 and 2.Conclusions: The BMI affects the disability in patients with chronic low back pain. [AMJ.2016;3(4):624–8] DOI: 10.15850/amj.v3n4.949
Correlation between Short-Term Memory and Achievement of Athletes Mustari, Ryandika Elvereza; Lubis, Leonardo; Kurniani, Nani
Althea Medical Journal Vol 4, No 3 (2017)
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Background: Human activity is largely related to thought processing or cognition. One of the most important components of cognition is memory. Individuals who undergo heavy activities, such as athletes, use a lot of memory in the subject’s activities, especially during competitions. The purpose of this study was to find out whether there was a correlation between the capability of short term memory with the performance of an athlete during a competition, especially those measured by achievements.Methods: This study was an analytic observational correlation study with a cross-sectional design and involved 201 athletes as respondents from 12 branches of sports. The study was conducted in the Indonesian National Sports Committee (KONI) building from September to November 2015. Digit Span Forward and Backward were used to collect short term memory data and was performed after a consent form and the respondent’s identity was recorded. The athlete’s achievements data was gathered by an interview and recapitulation of athlete’s achievements in the last five years.Results: OA total of 186 data was analyzed and found a negative and  insignificant correlation between achievement and short-term memory based on digit span tests both forward (r=0.095 p=0.196) and backward(r=0.039 p=0.196). Conclusions: There is no correlation between short term memory and the achievements of an athlete.   
Korelasi Peningkatan Kadar Neuron Spesific Enolase dengan Derajat Keparahan dan Luaran Fungsional Pasien Stroke Infark Aterotrombotik Akut Wardiyani, Neti Sri; Nurimaba, Nurdjaman; Kurniani, Nani
Majalah Kedokteran Bandung Vol 42, No 2 (2010)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Pada stroke iskemik terjadi kerusakan neuronal serta penurunan glikolisis aerob akibat menurunnya kadar glukosa. Neuron specific enolase (NSE) yang terdapat pada jaringan neuronal banyak tidak terpakai sehingga kadarnya meningkat. Pada kerusakan neuronal serta gangguan membran sel, sawar darah otak terganggu sehingga NSE berdifusi kedalam ekstraselular dan cairan serebrospinal. Peningkatan kadar NSE serum juga berhubungan dengan volume infark dan luasnya kerusakan otak. Penelitian ini bertujuan untuk mengetahui peningkatan kadar NSE pasien stroke infark aterotrombotik akut, serta korelasinya dengan derajat keparahan stroke dan luaran fungsional. Rancangan penelitian adalah observational analytic dengan pendekatan kohort. Pasien stroke infark aterotrombotik fase akut sebagai kasus, sedangkan kontrolnya orang sehat. Penelitian dilakukan di Rumah Sakit Dr. Hasan Sadikin Bandung, mulai Februari sampai Agustus 2008. Pemeriksaan kadar NSE serum dan penilaian tingkat keparahan stroke berdasarkan National Institutes of Health Stroke Scale (NIHSS) dilakukan saat masuk rumah sakit, sedangkan luarannya dinilai pada hari ketujuh dengan indeks Barthel. Analisis yang digunakan adalah analisis bivariat dengan uji statistik Mann-Whitney dan uji Pearson. Dari 43 kasus dan 43 kontrol, didapatkan perbedaan kadar NSE serum yang bermakna rata-rata=11,41 [5,07] ng/mL berbanding 8,93 [3,03] ng/mL (p=0,019). Terdapat korelasi yang bermakna peningkatan kadar NSE serum dengan derajat keparahan yang dinilai berdasarkan skala NIHSS (p=0,024), juga dengan luaran fungsional (p=0,012). Nilai akurasi paling tinggi terdapat pada kadar NSE serum 12ng/mL, dengan sensitivitas 42% dan spesifisitas 84%. Kesimpulan dari penelitian ini adalah kadar NSE serum berkolerasi dengan derajat keparahan serta keluaran fungsional penderita stroke infark. [MKB. 2010;42(2):62-8].Kata kunci: Kadar neuron specific enolase,stroke infark, NIHSS, Indeks BarthelCorrelation of Serum Neuron Specific Enolase with Severity and Functional Outcome in Acute Atherothrombotic Infarction Stroke PatientsNeuronal damage and decreasing aerobic glicolysis process in ischaemic stroke are caused by lowering level of blood glucose. The amount of neuronal intrasitoplasmic glicolytic enolase enzyme, also known as neuron specific enolase, increases in blood circulation because it is not used anymore in damage neuron. So the mechanism failure in blood-brain barrier, as result of neuronal and cell membrane damage, causes NSE diffusion to extracellular and cerebrospinal fluid, then NSE level increases in blood serum and cerebrospinal fluid in acute cerebral infarction. Elevating NSE level is also connected with infarct volume and the extent of brain damage. The aim of this study was to evaluate connection between upgrading NSE serum level in acute atherothrombotic-stroke infarction patients, level of stroke incompatibility, and functional outcome. The method of study was observational analytic with kohort study. Subjects of study were divided into case group consisted of acute atherothrombotic-stroke infarction patients and control group consisted the healthy person. The data was collected in Hasan Sadikin Hospital between February to August 2008. Evaluating patients was performed to get descriptions on NSE serum level, level stroke incompability measuring by NIHSS scoring at the first time entering the hospital, and Barthel index scoring at seventh day of treatment. This study was analyzed by bivariat analysis using Mann Whitney statistic test and Pearson correlation test. There were 43 patients in each group. There was a significantly difference in NSE serum level on case group (mean was 11.41 [5.07] ng/mL) in comparison to those on control group (mean was 8.93 [3.03] ng/mL), p=0.019 . There was a significantly correlation between raising NSE serum level on case group and level of stroke incompatibility measuring by NIHSS scoring and also with functional outcome according to Barthel index scoring. The highest accuration value of NSE serum level was 12 ng/mL with 42% sensitivity and 84% specificity. The conclusion was neuron specific enolase serum level has correlation with severity and functional outcome in acute atherothrombotic infarction stroke patients. [MKB. 2010;42(2):62-8].Key words: Neuron specific enolase serum level, stroke infarction, NIHSS, Barthel index DOI: http://dx.doi.org/10.15395/mkb.v42n2.218
Correlation between Short-Term Memory and Achievement of Athletes Mustari, Ryandika Elvereza; Lubis, Leonardo; Kurniani, Nani
Althea Medical Journal Vol 4, No 3 (2017)
Publisher : Althea Medical Journal

Show Abstract | Original Source | Check in Google Scholar

Abstract

Background: Human activity is largely related to thought processing or cognition. One of the most important components of cognition is memory. Individuals who undergo heavy activities, such as athletes, use a lot of memory in the subject’s activities, especially during competitions. The purpose of this study was to find out whether there was a correlation between the capability of short term memory with the performance of an athlete during a competition, especially those measured by achievements.Methods: This study was an analytic observational correlation study with a cross-sectional design and involved 201 athletes as respondents from 12 branches of sports. The study was conducted in the Indonesian National Sports Committee (KONI) building from September to November 2015. Digit Span Forward and Backward were used to collect short term memory data and was performed after a consent form and the respondent’s identity was recorded. The athlete’s achievements data was gathered by an interview and recapitulation of athlete’s achievements in the last five years.Results: OA total of 186 data was analyzed and found a negative and  insignificant correlation between achievement and short-term memory based on digit span tests both forward (r=0.095 p=0.196) and backward(r=0.039 p=0.196). Conclusions: There is no correlation between short term memory and the achievements of an athlete.   
Correlation between Body Mass Index and Disability in Patient with Chronic Low Back Pain Teck, Tiang Soon; Prabowo, Tertianto; Kurniani, Nani
Althea Medical Journal Vol 3, No 4 (2016)
Publisher : Althea Medical Journal

Show Abstract | Original Source | Check in Google Scholar

Abstract

Background: Low back pain is discomfort presented below the margin of the 12th thoracic rib and above the inferior gluteal fold with or without leg pain. It is also a major cause of disability. Several risk factors have been identified for contributing low back pain. It is important to determine whether body mass index (BMI) can affect the disability in patients with chronic low back pain. Oswestry disability index (ODI) questionnaire has been used to measure the severity of disability. Thus, the focus of study was to determine correlation between BMI and disability in patients with chronic low back pain. Methods: Sixty two patients aged 18 years old or more who were clinically diagnosed as having low back pain at least 3 months participated in this study in the period of October to November 2015 in the Department of Physical Medicine and Rehabilitation of Dr. Hasan Sadikin General Hospital Bandung. Total sampling method was used. Gender, age, weight, height, BMI and disability were recorded using ODI questionnaire. This analytical study was cross sectional study and the ordinal variable was analyzed using linear regression analysis.Results: Females had higher proportion (77). Chronic low back pain patients were equally distributed on normal weight and overweight categories. Patient with chronic low back pain had higher chances of developing moderate disability. There were positive correlation between BMI and disability. Nevertheless, there was no statistically analysis difference between model 1 and 2.Conclusions: The BMI affects the disability in patients with chronic low back pain. [AMJ.2016;3(4):624–8] DOI: 10.15850/amj.v3n4.949
Characteristics of Patient with Brachial Plexus Injury in Neurophysiology Laboratory of Dr. Hasan Sadikin General Hospital Bandung, Indonesia, from 2003 to 2012 Kurnianto, Ivan; Kurniani, Nani; Soenggono, Arifin
Althea Medical Journal Vol 2, No 3 (2015)
Publisher : Althea Medical Journal

Show Abstract | Original Source | Check in Google Scholar

Abstract

Background: Brachial plexus is a network of nerves that controls the upper limb. Unfortunately, it can be injured easily which is called brachial plexus injury (BPI). It can cause disability. Until now, the epidemiology of BPI in Indonesia is still lacking. The aim of this study was to describe the characteristics of patients with BPI in Bandung, in order to increase knowledge and attention of health care provider and community to prevent BPI.Methods: This was a descriptive retrospective study. Data from medical records of patients with BPI who underwent electromyography (EMG) in Neurophysiology Laboratory Dr. Hasan Sadikin General Hospital, Bandung from 2003 to 2012 were collected. The data included age, sex, mode of injury, affected side and distribution of paralysis. Collected data were presented as percentages shown in tables.Results:  A total of 91 cases were collected during study period, which consisted of 69 males and 22 females (76% vs. 24%). Most of them were in productive age group (11−20 years and 21−30 years). The main cause of brachial plexus injury was traffic accident (76%), followed by birth injury. Distribution of paralysis was mostly in postganglionic area of cervical (C)5, C6, C7, C8 and thoracal (T)1 (67%). Around two third of the cases involved the right side of upper limb.Conclusions: The study showed that most of patients with BPI are male in their productive ages. Traffic accident is the most common cause, and the most affected side is the right side of upper limb. DOI: 10.15850/amj.v2n3.529