Agus Kartono
Physics Department, Faculty of Mathematical and Natural Sciences-Institut Pertanian Bogor Jl. Meranti, Building Wing S, 2nd Floor, Kampus IPB Darmaga, Bogor 16680, Indonesia

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Studi Awal Pemodelan Perlakuan Virotherapy yang Menggunakan Virus Campak pada Tumor Paru-paru Tikus

BERKALA FISIKA Vol 13, No 4 (2010): Berkala Fisika
Publisher : BERKALA FISIKA

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Abstract

The interaction model dynamics between tumor and viruses based on the interaction phenomenon between the three populations, namely: population of uninfected tumor cells, tumor cell population infected with the virus and the virus population. This study aimed to see the interaction between non-infected tumor cells, tumor cells infected with viruses and viruses, so it can be modeled using virotherapy treatment of measles virus in mouse lung tumors. Model parameters obtained from experimental data. Numerical Solution of the models suggest that the dose of the virus play an important role in determining the outcome of tumor therapy. Tumor growth can be slowed by using this virotherapy, but the tumor can not be killed as a whole. Keywords: model dynamics, virotherapy, measles virus, mouse lung tumors t; mu � ni�o� P� :IN> viscosity, indeks of refraction, transparent liquid 

Solusi Numerik Model Dinamik Perlakuan Immunotherapy pada Infeksi HIV-1

BERKALA FISIKA Vol 13, No 1 (2010): Berkala Fisika
Publisher : BERKALA FISIKA

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Abstract

There are several types of treatment options that can slow the progression of HIV that can be offered if the number of CD4 + cells has been known for certain, one treatment is by immunotherapy with interleukin-2 (IL-2). This type of treatment is to increase the immune system that can help the body fight against the infection itself. Efforts to raise an immune response would be appropriate to reduce the amount of virus. This brings new hope for treatment of HIV infection and the type of treatment is being researched. Interleukin-2 (IL-2) is most of the cytokines which are proteins made by the body. T-helper cells, a type of white blood cells, produce IL-2 when they were stimulated by infection. In this study, a model of HIV disease progression than individuals not treated can be expressed in a mathematical model, and also expressed immunotherapy model to see the dynamics of viral populations and the population of CD4 + T cells from HIV disease based on ordinary differential equation (ODE). This study aims to calculate the numerical solution immunotherapy mathematical model in HIV infection and a mathematical model to predict the outcome of immunotherapy treatment strategies in HIV infection. Keywords: HIV, CD4 + T cells, immunotherapy, mathematical modeling

Studi Awal Pemodelan Perlakuan Virotherapy Yang Menggunakan Virus Campak Pada Tumor Paru-Paru Tikus

BERKALA FISIKA Vol 13, No 2 (2010): Berkala Fisika, Edisi Khusus
Publisher : BERKALA FISIKA

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Abstract

The interaction model dynamics between tumor and viruses based on the interaction phenomenon between the three populations, namely: population of uninfected tumor cells, tumor cell population infected with the virus and the virus population. This study aimed to see the interaction between non-infected tumor cells, tumor cells infected with viruses and viruses, so it can be modeled using virotherapy treatment of measles virus in mouse lung tumors. Model parameters obtained from experimental data. Numerical Solution of the models suggest that the dose of the virus play an important role in determining the outcome of tumor therapy. Tumor growth can be slowed by using this virotherapy, but the tumor can not be killed as a whole. Keywords: model dynamics, virotherapy, measles virus, mouse lung tumors

NUMERICAL ANALYSIS OF ENZYME MEMBRANE THICKNESS ON THE RESPONSE OF AMPEROMETRIC BIOSENSOR

Jurnal Sains Materi Indonesia 2011: Agustus 2011 - Edisi Khusus
Publisher : BATAN

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Abstract

This paper presents a one-dimensional-in-space mathematical model of an amperometric biosensor. The model is based on the reaction-diffusion equations containing a non-linear term related to Michaelis Menten kinetics of the enzymatic reactions. The model is solved numerically by applying the Finite Difference Method (FDM). This model describes the biosensor response to active time of enzymatic reaction in membrane layer. Using numerical solution, the influence of the thickness of enzyme membrane on the biosensor current response was investigated. The numerical results of the biosensor operation showed the monotonous change of the biosensor current response versus the membrane thickness.Key words:  Amperometric biosensor, Reaction-diffusion, Michaelis-Menten kinetics, Finite Difference Method, Membrane thickness.

Simulating the Aerodynamics Profiles of NACA 4312 Airfoil in Various Incoming Airspeed and Gurney Flap Angle

Omega: Jurnal Fisika dan Pendidikan Fisika Vol 4 No 1 (2018)
Publisher : Program Studi Pendidikan Fisika UHAMKA

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Abstract

Simulations of the aerodynamics performance of NACA 4312 airfoil at various gurney flap angles and incoming airspeed (wind velocities) have been conducted. The gurney flaps size was set at 5.0% length of the chord line. Two airfoil models with gurney flap at 45° and 90° were simulated and compared with the results of plain airfoil (without gurney flap) model with the incoming airspeed of 10.0 m/s, 70.0 m/s and 200.0 m/s. The results have shown that increasing the value of gurney flap angle to 45° and 90° will increase the lifting force of the airfoil and decrease the drag force.