T. Fadrial Karmil
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Anti-bacterial activity of rosella flowers extract (Hibiscus sabdariffa linn) in inhibiting bacterial growth methicillin-resistant Staphylococcus aureus Hayati, Zinatul; Yulia, Winda; Karmil, T. Fadrial; Azmy, Abdullah
Proceedings of The Annual International Conference, Syiah Kuala University - Life Sciences & Engineering Chapter Vol 2, No 1 (2012): Life Sciences
Publisher : Syiah Kuala University

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Infections caused by bacteria Methycillin Resistant Staphylococcus aureus (MRSA) has become a worldwide health problem because of its increasing incidence. Rosella flower (Hibiscus sabdariffa Linn) has been known to have efficacy as an antibacterial. The purpose of this study is to determine the antibacterial activity of rosella flower extract in inhibiting the growth of MRSA. This study is an experimental research laboratory using rosella flower extract as a treatment, vancomycin as a positive control and distilled water as negative control. Fresh and dried rosella flowers crushed and then macerated with 96% ethanol for 24 hours. The filtrate obtained was concentrated by rotary evaporator at a temperature of 35 ˚ C-40 ˚ C and then diluted to a concentration of 12.5%, 25%, 50% and 75%. Phytochemical test is then performed. S.aureus bacteria isolated from clinical specimens in RSUDZA. Test of the antibacterial activity of rosella flower extract performed using Kirby Bauer disc diffusion method. Parameters on the disc were measured in millimeters MRSA. The data obtained were statistically analyzed and grouped into categories of Greenwood (1995). Phytochemical test results indicate the presence of rosella flower extract contains flavonoids, tannins, saponins, triterpenoids and alkaloids. Test results of the inhibition of rosella flower extract concentration of 12.5%, 25%, 50% and 75% of the growth of MRSA each inhibitory zone formed with an average diameter of 14.2 mm, 19.2 mm, 22.8 mm and 24.18 mm, whereas the positive control and negative control respectively of 19.8 mm and 5 mm. The results of data analysis showed that the ethanol extract of rosella flowers significant effect in inhibiting the growth of MRSA by the value of p <0.05. Based on the criteria of Greenwood, rosella flower extract ethanol concentration of 50% and 75% belong to the category of strong inhibitory power in inhibiting the growth of MRSA, a concentration of 25% falls into the category of being and the concentration of 12.5% falls into the category of weak. The results can be concluded that rosella flower ethanol extract can inhibit the growth of MRSA.
Evaluation of viability and nutritive value of Indigofera tinctoria as a potential animal feeding in Aceh Province, Indonesia Yaman, M. Aman; Daud, M.; Zulfan, .; Jufri, Yadi; Karmil, T. Fadrial
Proceedings of The Annual International Conference, Syiah Kuala University - Life Sciences & Engineering Chapter Vol 2, No 1 (2012): Life Sciences
Publisher : Syiah Kuala University

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A series of studies related to animal feeding technology to stimulate the egg production and egg quality with the development of a cheap source of protein types and useful has been done through the evaluation of viabilityand nutritive value of Indigofera tinctoria and in vivo treatments on quail and chicken. Research conducted since 2010 to October 2012 with a focus on increasing the ability to grow the Indigofera’s seed under soaking treatment inauxin hormone and testing the nutritional value on quail and chicken. The first study related to the viability testing is done by soaking the seed of Indigofera in auxin hormone before planting in the field. The study consisted of 4treatments and 5 replications of soaking period, namely: control, B (12 hours), C (24 hours) and D (32 hours) in the solution. The parameters measured were: viability and growth of seed and dry matter content of Indigofera leaf. Thesecond study tested the nutritive value of Indigofera in the ration of laying chickens and quail. Treatments were: 0, 2, 4 and 6% of Indigofera leaf in the ration. Parameters observed in were: egg production, fertility, hatchability andegg quality. The results showed that the viability of the Indigofera’s seed with soaking treatment significantly increased to 80% and soaking for 32 hours resulted a higher viability. The treatment of soaking in auxin hormonealso increased nutrient content of indigofera leaf especially protein. In terms of nutritional value, supplement of Indigofera leaf was very useful to improve the production and quality of eggs in both local laying chickens and quail.The addition of Indigofera leaf in the ration up to 5% also reduced the feed consumption and increasead Haugh unit of egg chicken. From these results it was concluded that the viability of Indigofera tinctoria increased by soaking inauxin hormone for 12-32 hours. These treatments also stimulated the dry matter and protein contents in Indigofera’s leaf. The supplement of Indigofera tinctoria leaf as much as 1-5% in the ration also improved the egg production and quality of local chicken and quail. It was indicated that Indigofera tinctoria contains not only protein and amino acids but also vitamin and mineral for egg quality
PENGARUH PEMBERIAN VITAMIN E TERHADAP KADAR MALONDIALDEHIDA (MDA) SERUM TIKUS PUTIH (Rattus norvegicus) DIABETES MELITUS (The Effect of Vitamin E to Malondialdehyde (MDA) Serum Level in Diabetes Mellitus Induced White Rat (Rattus norvegicus)) vera, bella; dasrul, dasrul; azhar, al; karmil, t. fadrial; riady, ginta; sabri, mustafa
JURNAL ILMIAH MAHASISWA VETERINER Vol 2, No 2 (2018): FEBRUARI - APRIL
Publisher : JURNAL ILMIAH MAHASISWA VETERINER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/jim vet..v2i2.6760

Abstract

ABSTRAKPenelitian ini bertujuan untuk mengetahui pengaruh vitamin E terhadap kadar MDA serum tikus putih (Rattus novergicus) diabetes melitus. Penelitian ini menggunakan rancangan acak lengkap (RAL). Sebanyak 25 ekor tikus dibagi secara acak menjadi 5 kelompok: kelompok kontrol negatif yaitu tikus non-diabetes (KN), kelompok kontrol positif yaitu tikus diabetes tanpa diberi vitamin E (KP), tikus diabetes yang diberi vitamin E dosis 50 IU/kgbb/hr (P1),100 IU/kgbb/hr (P2), dan 150 IU/kgbb/hr (P3) selama 28 hari. Selama penelitian tikus diberi pakan dan air minum secara ad libitum. Pada hari ke-29, dilakukan pengkoleksian serum darah untuk pemeriksaankadar MDA secara spektofotometri. Data yang diperoleh dianalisis menggunakan analisis varian (ANAVA) dan dilanjutkan dengan uji Duncan. Hasil penelitian menunjukkan rata-rata (±SD) kadar  MDA serum adalah 13,44 ± 3,15 µmol/l (KN), 22,18 ± 6,44 µmol/l (KP),19,01 ± 5,25 µmol/l (P1), 14,86 ± 4,11 µmol/l (P2), dan 12,25 ± 2,45 µmol/l (P3).Hasil penelitian menunjukkan bahwa pemberian vitamin E dapat menurunkan kadar MDA serum. Pemberian vitamin E dosis 150 IU/kgbb/hari lebih baik dibandingkan dengan dosis 100 IU/kgbb/hari dan 50 IU/kgbb/hari dalam menurunkan kadar MDA serum. Kesimpulan dari penelitian ini adalah pemberian vitamin E dapat menurunkan kadar MDA serum tikus putih diabetes melitus.ABSTRACT             The aim of this study were to determine the effect of vitamin E on serum MDA level in white rat (Rattus novergicus) diabetes mellitus. This study used a complete randomized design (CRD). 25 rats were divided randomly into 5 groups: negative control group in which the rats were non-diabetes (KN), potitive control group in which the rats diabetes rats without E vitamin (KP), diabetes rats given vitamin E with the doses of 50 IU/kgbw/day (P1), 100 IU/kgbw/day (P2), and 150 IU/ kgbw/day (P3) for 28 days. During the study, rat were fed with food and water in ad libitum. On the 29th day,the collection of blood serum was done to check the MDA level using the spectophotometer.Acquired data were analysed  by using Analysis of Variance (ANOVA) then proceed with Duncan test. The result showed the mean (±SD)of MDA serum level was 13,44 ± 3,15 µmol/l (KN), 22,18 ± 6,44 µmol/l (KP),19,01 ± 5,25 µmol/l (P1), 14,86 ± 4,11 µmol/l (P2), dan 12,25 ± 2,45 µmol/l (P3).The results of the study showed that fedding of vitamin E could reduce serum MDA levels.The fedding of vitamin E150 IU/kgbw/day was better than 100 IU/kgbw/day and 50 IU/kgbw/day in lowering serum MDA levels. The conclusion of the study showed that fedding of vitamin Ecandecrease the MDAserum level in diabetes mellitus induced white ratThe Effect of Vitamin E to Malondialdehyde (MDA) Serum Level in Diabetes Mellitus Induced White Rat (Rattus norvegicus)
PENGARUH PAPARAN TIMBAL (Pb) TERHADAP LAJU PERTUMBUHAN IKAN NILA (Oreochromis nilloticus) Rahayu, Nur Inda; Rosmaidar, Rosmaidar; Hanafiah, M.; Karmil, T. Fadrial; Helmi, T. Zahrial; Daud, Razali
JURNAL ILMIAH MAHASISWA VETERINER Vol 1, No 4 (2017): AGUSTUS-OKTOBER
Publisher : JURNAL ILMIAH MAHASISWA VETERINER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/jim vet..v1i4.4757

Abstract

 Penelitian ini bertujuan mengetahui tingkat konsentrasi timbal   (Pb)  yang berpengaruh terhadap laju pertumbuhan ikan nila (Oreochromis nilloticus). Penelitian ini menggunakan ikan nila sebanyak 40 ekor dengan kriteria: sehat; bobot badan 15 – 18 gram; umur ± 2 bulan; jenis kelamin jantan. Penelitian ini menggunakan 4 kelompok perlakuan, P0 sebagai kontrol ikan hanya diberi pakan pelet, P1 diberikan paparan timbal  6,26 mg/L  dan pakan pelet, P2 diberikan paparan timbal 12,53 mg/L  dan pakan pelet dan P3 diberikan paparan timbal 25,06 mg/L  dan pakan pelet,  masing-masing perlakuan terdiri dari 10 ekor ikan nila. Perlakuan dilakukan selama 30 hari dan Pengukuran pertumbuhan ikan dilakukan setiap 10 hari sekali dengan cara menimbang bobot dan mengukur panjang tubuh setiap individu ikan. Hasil penelitian menunjukkan rata-rata panjang tubuh ikan nila P0 (9,45±1,06), P1 (8,89±0,90), P2 (8,86±0,87), dan P3 (8,66±0,85). Rata-rata berat ikan nila P0 (23,38±4,50), P1 (19,75±2,27), P2 (19,15±2,10), dan P3 (18,65±2,00). Laju pertumbuhan spesifik P0 (38,7%), P1 (8,3%), P2 (4,3%), dan P3 (3,3%). Laju pertumbuhan panjang harian individu ikan P0 (0,46 mm/d), P1 (0,27 mm/d), P2 (0,21 mm/d), dan P3 (0,19 mm/d). Kesimpulan dari penelitian bahwa konsentrasi timbal  dan lamanya paparan berpengaruh terhadap laju pertumbuhan ikan.  Konsentrasi timbal  yang sangat berpengaruh adalah 25,06 mg/L. ABSTRACTThe aims of this research was to find out to determine the level of Lead (Pb) concentration that affect the rate of growth tilapia (Oreochromis nilloticus). This study used 40 tilapia with criteria: healthy; body weight 15-18 gram; age ± 2 month; male sex. This study used 4 treatment groups, P0 as control, fish fed only pellets, P1 was given lead exposure 6,26 mg/L and pellet, P2 was given lead exposure 12,53 mg/L and pellet and P3 was given lead exposure 25,06 mg/L and pellet. Each treatment consisted of 10 tilapia fish. Treatment carried out for 30 days and measure every 10 days. The results showed the average length of tilapia fish P0 (9,45±1,06b); P1 (8,89±0,90a); P2 (8,86±0,87a) and P3 (8,66±0,85). Average weight of tilapia fish P0 (23,38±4,50); P1 (19,75±2,27); P2 (19,15±2,10) and P3 (18,65±2,00). Spesific growth rate P0 (38,7%); P1 (8,3%); P2 (4,3%) and P3 (3,3%). The rate of long-term growth of individual fish P0 (0,46 mm/d); P1 (0,27 mm/d); P2 (0,21 mm/d) and P3 (0,19 mm/d). In conclusion, it showed that the concentration of lead (Pb) and the duration of exposure has affect the growth rate of fish. The influential concentration of lead is 25,06 mg/L.
16. The Number Of Leukocyte And Leukocyte Differential In Broilers That Infected With Eimeria tenella And Given Neem Leaf Extract And Jaloh Extract Aulia, Rizki; Sugito, Sugito; Hasan, M.; Karmil, T. Fadrial; Gholib, Gholib; Rinidar, Rinidar
Jurnal Medika Veterinaria Vol 11, No 2 (2017): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v11i2.4667

Abstract

The aim of this research was to determine the effect of giving neem leaf extract combined with jaloh towards the total of leukocytes and differential leukocyte in broilers that was infected with Eimeria tenella. This research samples were 20 Cobb stain broilers 14 days old. Design the research was complete randomized design with five treatments and each treatment consists of four repetitions. First treatment (P1) as negative control which was only given mineral water; second treatment (P2) as positive control was is given 5 mg/L anti-stress commercial in drinking water; Third treatment (P3) was given 1000 mg/L Jaloh extract; Fourth treatment (P4)was given 250mg/L neem extract; and fifth treatment (P5)was given 1000mg/L jaloh extract combined with 250mg/L neem extract. Anti-stress commercial and extract treatment dissolved in drinking water. The treatment start from 08.00 until 18.00 for ten days. Next in the 11th day (chicken 25 days old)was inoculated Eimeria tanella sporulatif as much as 1 x 104 ookista/ml orally. Then the blood was taken sampling when the chicken 30 days old (five days after infected). Blood sampling was done in the brachial vein. Furthermore, the number of leukocytes and differential leukocyte.Was calculated data were analyzed using complete randomized design with the help of SPSS for Windows 1.8 program. The result of this research showed that giving jaloh and neem leaf extract were not giving significant effect (P>0,05) towards the number of leukocyte as well as differential leukocyte of broilers that was infected with Eimeria tenella. The conclusion of this research were giving jaloh leaf extract and neem for 10 days was not giving significant effect towards number of leukocytes and differential leukocyte broilers that infected with Eimeria tenella
KORELASI ANTARA DEHIDRASI DENGAN FAKTOR-FAKTOR KLINIS PADA ANAK KAMBING KACANG LOKAL (Capra aegagrus hircus)(Correlation between Dehydration and Assessment Clinical Factors in Kacang Goatlings (Capra aegagrus hircus)) Roslizawaty, Roslizawaty; Rusli, Rusli; Hadi, Isra; Karmil, T. Fadrial; Amiruddin, Amiruddin; Syafruddin, Syafruddin
Jurnal Medika Veterinaria Vol 10, No 1 (2016): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v10i1.4029

Abstract

The purpose of this study was to determine the dominant factor that clinically influent the occurrence of dehydration in goats aged 10-14 days old, in order to enhance the accuracy in diagnoinge the state of hydration. Ten native kacang goatlings were used as research objects. Kacang goatlings were dehydrated until loss 10% of their bodyweight by inducing diuretics furosemide (2mg/kg body weight every 4 hours) using intramuscularly, orally administration of spironolactone (50 mg every 8 hours) and hydrochlorothiazide (50 mg every 8 hours). Regression analysis was used to verify the correlation between clinical factors that considered potential, which are enopthalmus, skin turgor (back, neck and upper eyelid), capillary refill time, pulsus, breath, and body temperature. The results showed that enopthalmus, skin turgor on back and eye region has close correlation with dehydration occurrence with coefficient determinant R2 are 0.92; 0.90 and 0.81 respectively. It can be concluded that these three parameters can be used as predictor towards dehydration occurrence.
23. IDENTIFIKASI PARASIT PADA IKAN LELE DUMBO (Clarias gariepinus) DI DESA LAMBRO DEYAH KECAMATAN KUTA BARO KABUPATEN ACEH BESAR Identification of Parasites in Catfish (Clarias gariepinus) in Lambro Deyah Kuta Baro Aceh Besar Rizki, Adistya Putra; Fahrimal, Yudha; Daud, Razali; Karmil, T. Fadrial; Hambal, Muhammad; Z, Zuhrawati
Jurnal Medika Veterinaria Vol 10, No 2 (2016): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v10i2.4390

Abstract

The study aimed at identifying the types of parasites that infect catfish as well as to determine the prevalence of the parasite species. A total of 30 catfish were collected using nets then examined at Parasitology Laboratory, Veterinary Medicine Faculty, Syiah Kuala University Banda Aceh. Ectoparasites examination was carried out by directly observed the outer surface of fish body and by mucus smear examination microscopically. While endoparasites examination was done by observation on the inner surface of the digestive tract. The study revealed that five types of parasites infected catfish were Dactylogyrus (43.33%), Gyrodactylus (20%), Tricodina (3.33%), Camallanus sp (3.33%), and unidentified worm (3.33%). ____________________________________________________________________________________________________________________ Key words: catfish, ectoparasite, endoparasite
6. The Effect of Celery Leaves Infusa (Apium graveolens L) on Reducing Level of Blood Glucose on Rat (Rattus norvegicus) Induced by Alloxan Syarifahnur, Fatin; Roslizawaty, Roslizawaty; Amiruddin, Amiruddin; Hasan, Muhammad; Karmil, T. Fadrial; Budiman, Hamdani
Jurnal Medika Veterinaria Vol 12, No 1 (2018): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v12i1.4335

Abstract

This study aims to investigate the effect of celery leaf infusa on decreasing  level of blood glucose in rat (Rattus norvegicus). Twenty five rats were divided into 5 groups namely first treatment group (P1) as negative control. Second treatment group (P2) as positive control, rats were induced with alloxan. Third treatment group (P3) rats were induced with alloxan and given 5% celery leaf infusa. Fourth treatment group (P4) rats were induced with alloxan and given 10% celery leaf infusa. Fifth treatment group (P5) rats were induced alloxan and given 15% celery leaf infusa for 14 days. The level of blood glucose of the rat was determined before treatment, after given aloksan and after given celery leaf infusa. Data were analyzed using Analysis of Varians (ANOVA). Results showed that administration of celery leaf infusa  for 14 days, show significant effect to decreasing level of glucose in rat (P<0.01). It can be concluded that the administration of celery leaf infusa  concentrated 5%, 10% and 15% for 14 days show significant effect to decreased level of glucose in rats.