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6
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Experimental Infection of Taenia saginata eggs in Bali Cattle: Distribution and Density of Cysticercus bovis

Jurnal Veteriner Vol 10, No 4 (2009)
Publisher : Jurnal Veteriner

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Abstract

The objective of this study was to observe the development, distribution, and infection density ofTaenia saginata metacestodes in Bali cattle. Three Bali cattle were experimentally infected with T. saginataeggs which were collected from taeniasis patients. The experimental animal was inoculated with : i)1000,00 T. saginata; ii) 500,000 eggs; and iii) 1,000,000 eggs, respectivelly 100,000 (cattle 1), 500,000(cattle 2), and 1,000,000 (cattle 3) T. saginata eggs, respectively. To observe the development of cysticerci,all cattle were slaughtered at 24 weeks post infection. To observe their distribution and density, slicingwas done to the cattle?s tissues. The study results showed that cysts were found distributed to all muscletissues and some visceral organs such as heart, diaphragm, lungs, and kidney of the cattle infected with100,000 and 500,000 T. saginata eggs. Density of the cyst was in the range of 11 to 95 cysts per 100 gramsof tissue. The highest density was noted in the heart (58/100 grams) and in diaphragm (55/100 grams).This study has confirmed that T. saginata eggs derived from taeniasis patient in Bali, if infected to Balicattle can develop and spread to all muscle tissues and some visceral organs. From this study it wasconcluded that it is necessary to include the heart in the meat inspection at slaughter house for possibilityof T. saginata cyst infection.$?

The problem of Taeniasis and Cysticercosis in Irian Jaya, Indonesia

Medical Journal of Indonesia Vol 10, No 2 (2001): April-June
Publisher : Faculty of Medicine Universitas Indonesia

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Abstract

The disease, caused by the adult and larva of Taenia solium, spread to the western part of Irian Jaya crossing the border of Indonesian to Papua New Guinea. Twenty local health centers reported 638 and 945 new cases with epileptic seizures in 1994 and 1995 respectively. Questionnaires were distributed to 31 respondents with results as follows: 83.9% were illiterate, 93.6% farmers and all of them sometimes ate not well-cooked pork; no other meat was consumed. In this area no healthy drinking water was available; also there was no sanitary facilities. Pigs were roaming around the houses, rarely the pigs were put behind fences. After international collaboration with several institutions, e.g with Asahikawa Medical College, Japan, 29 serum samples were examined by immunoblot with positive results for 67% of the cases suffering from epileptic seizures and 65% with subcutaneous nodules. Moving of people to other areas personal and environmental hygiene, the importance of pigs in the daily life of the community were important issues in maintaning the disease being caused by T.Solium in this area. (Med J Indones 2001; 10: 110-4)Keywords: Taenia solium, Irian Jaya, spreading, international collaboration

Multiple cysticercus nodules in skin and brain in a Balinese woman: A case report

Medical Journal of Indonesia Vol 11, No 3 (2002): July-September
Publisher : Faculty of Medicine Universitas Indonesia

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Abstract

A case of multiple subcutaneous and cerebral cysticercosis in a 33-year-old Balinese female, is reported. The patient suffered from seizures since adolescence, which was not treated. Since three years before admission she started developing multiple nodules in the skin, starting from her forehead and since a year ago also in other parts of the head and body such as shoulders, chest and back. Serum sample tested against cysticercus antigen by immunoblot assay against antigen of Taenia solium was positive. The copro-antigen test was also positive, indicating the presence of the adult worm in the intestines. The patient was treated with praziquantel for the adult T. solium infection and thereafter with albendazole for the larval stages, which resulted in obvious reduction of the cerebral cysts and most of the subcutaneous nodules disappeared. However the adult worm was not recovered in the 24 hours stool specimen and after one year the immunoblot test was still positive. (Med J Indones 2002; 11: 169-73) Keywords: cysticercosis, Taenia solium, praziquantel, albendazole

Treatment of taeniasis and cysticercosis with praziquantel and albendazole

Medical Journal of Indonesia Vol 14, No 4 (2005): October-December
Publisher : Faculty of Medicine Universitas Indonesia

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Abstract

Recent methods, doses and results of medical treatment on taeniasis/cysticercosis, a zoo-notic parasitic disease caused by Taenia solium and Taenia saginata are discussed. In cases of cysticercosis T. solium, especially neurocysticercosis the optimal length and dose of albendazole is a course of 8 days with doses of 15 mg/kg/day divided in two times added by 50 mg/day of prednisone in the morning. The drug is effective in almost any location of the parasites for 80-90% of macroscopic cysts seen by imaging studies. For taeniasis a single dose of praziquantel, 10-15 mg/kg achieves cure rates of more than 90%. Side effects such as nausea, headache and abdominal pain are mild.  Evaluation of drug treatment is done by clinical, radiological and serological evaluation. In Papua (=Irian Jaya) nine cases with suspected neurocysticercosis, serologically positive, were treated with 1200 mg single dose albendazole for 15 days. Prednisonetablets, three times daily one tablet, 5 mg during 7 days were added. After one year 6 cases were still serologic positive. At the same time praziquantel, 1200 mg, single dose was given to ten cases during 15 days and prednisone tablets, 3 times daily one tablet, 5 mg during 7 days. After one year 5 sero-positive cases were still found. Albendazole and praziquantel are both effective drugs for taeniasis and cysticercosis, with minor side effects. In addition symptomatic treatment should be given if necessary. (Med J Indones 2005; 14:253-7)Keywords: albendazol, praziquantel, cysticercosis, taeniasis

Present Situation and Problems of Cysticercosis in Animal in Bali and Papua

Jurnal Veteriner Vol 13, No 2 (2012)
Publisher : Jurnal Veteriner

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Abstract

Cysticercosis zoonotic parasitic disesase caused by Taenia solium larva, is a major public healthproblem. Cysticercosis results from the development of larval tapeworms in humans harboring adult T.solium or from ingesting soil containing eggs shed in the feces of humans, in areas where there are nolatrines. Humans are accidental intermediate hosts and pigs are the normal intermediate hosts. Clinicallythey are most serious when located in the central nervous system or in the eye where they persist formonths to years. Cysticercosis occurs worldwide primarily in developing country where pigs are raised,pork consumed and poor sanitation allows pigs’ access to human faeces. The occurance of the diseases isexpected to increase in relation to the growing demand for pork in those countries. In Indonesia cyticercosisis still a very important health problem, especially in Bali and Papua. The majority of the populations inBali and Papua are Hindus and Protestants/Catholics, respectively, so pork widely consumed in thoseislands. This brief review summarizes the present situation and problems of cysticercosis in animal inBali and Papua. Epidemiological data of the diseases were obtained from several sources.

A case report of disseminated cysticercosis in Bali, Indonesia

The Indonesian Journal of Infectious Diseases Vol 1, No 2 (2013): The Indonesian Journal of Infectious Diseases
Publisher : The Indonesian Journal of Infectious Diseases

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Abstract

Abstract. We reported the case of a 36-year-old Balinese man who disseminated cysticercosis, presented neuro-, subcutaneous- and oral-cysticercosis. Diagnosis of it was based on anamnesis, clinical examination including CT Scan, histopathological and serological examinations. The patient visited outpatient clinic of Sanglah Denpasar Hospital in Bali, in June 2003 with two subcutaneous nodules in the body. Serological examinations (ELISA and immnunoblot) used both purified glycoproteins and chimeric recombinant antigen were positive. The two subcutaneous nodules disappeared after treatment with albendazole. In January 2004, the patient presented neuro-, and oral-cysticercosis. CT Scan showed multiple active lesions in the brain. During the treatment with 800 mg albendazole daily during for one month. The side effects of it such as nausea and vomit were found in that patient. Antibody responses in ELISA and immnunoblot were still positive and follow up CT scan in May 2004, it showed that very similar figures as previously. Repeated treatment with 400mg albendazole daily for one and half month was applied. Antibody responses became low, and CT scan in March 2006 did not show any active cysts but only calcified lesions.