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Prevalence of Salmonella sp. on Hatched Failure of Eggs and One Week´s Duckling at The Hatchery Center For Alabio Duck in The District of Hulu Sungai Utara South Kalimantan Istiana, Istiana
Media Veteriner Vol 5, No 2 (1998): Media Veteriner
Publisher : Media Veteriner

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Abstract

Six hundred and sixty five eggs of hatched failure and 150 of ducklings, from the hatchery of Alabio duck at the District of Hulu Sungai Utara (HSU), South Kalimantan, were examined for Salmonella sp. The results showed that 45 samples of eggs (6.8 %) and 18 samples of ducklings were positive to Salmonella sp (12 %). The serotipe of Salmonella sp. from eggs samples were 17 isolates of S. typhimurium (2.6 %),26 isolates of S. sentenberg (3.9 %), 1 isolate of S. hadar (0.2 %) and 1 isolate of S. virchow (0.2 %); and from duckling samples there are 5 isolates of S. typhimurium (3.3 %), 4 isolates of S. senftenberg (2.7 %), 5 isolates of S. hadar (3,3 %) and 4 isolates of S. virchow (2,7 %).
Resistance status of Aedes aegypti larvae to temephos in West Banjarmasin Istiana, Istiana; Heriyani, Farida; Isnaini, Isnaini
Buski Vol 4, No 2 Des (2012)
Publisher : Buski

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Abstract

Abstract Temephos has been used in controlling vector of dengue hemorrhagic fever, Aedes aegypti since long time ago. Long and continous usage of insecticides can increase the occurrence of resistance. This research aim to know the resistance of Ae. aegyptiin West Banjarmasin. We used experimental study with post test only with control group design. There were 8 groups of temephos treatment; 0,005 ppm, 0,01 ppm, 0,015 ppm, 0,03 ppm, 0,045 ppm, 0,060 ppm, 0,075 ppm and 0,090 ppm. Each group was exposed for the Ae.aegypti larvae and dead larvae observed after 24 hours exposure. Based on probit analysis, effective doses of temephos to ki1l50% larvae (Lethal Concentraticn/l.Cj..) was between 0,0064 - 0,0126 ppm (average = 0,00957 ppm) and LCgg was between 0,0196 - 0,0340 ppm (average = 0,0243 ppm). This research indicated that Ae.aegypti larvae in West Banjarmasin is resistant to temephos.   Abstrak Larvasida temephos telah sejak lama digunakan dalam pengendalian vektor demam berdarah dengue Aedes aegypti. Penggunaan insektisida dalam waktu yang lama dan terus menerus dapat meningkatkan kejadian resistensi insektisida tersebut. Penelitian ini bertujuan untuk mengetahui status kerentanan larva Ae.aegypti terhadap temephos di Kecamatan Banjarmasin Barat. Penelitian ini merupakan studi eksperimental dengan rancangan post test only with control group design dengan 8 kelompok perlakuan yaitu kelompok dosis temephos 0,005 ppm, 0,01 ppm, 0,015 ppm, 0,03 ppm, 0,045 ppm, 0,06 ppm; 0,075 ppm dan 0,09 ppm. Masing-masing kelompok perlakuan dipaparkan terhadap larva Ae. aegypti dan kematian larva dilihat setelah 24 jam pemaparan. Berdasarkan analisis probit, menunjukkan bahwa dosis temephos yang efektif membunuh 50% larva (Lethal Concentration/LC50) 24 jam berkisar antara 0,0064-0,0126 ppm dengan rata-rata 0,00957 ppm dan LCgg 24 jam berkisar antara 0,0196-0,0340 ppm dengan rata-rata 0,0243 ppm. Penelitian ini menunjukkan bahwa larva Ae. aegypti di Kecamatan Banjarmasin Barat sudah resisten terhadap temephos
PENGARUH INFEKSI KECACINGAN TERHADAP STATUS GIZI PADA ANAK DI SDN 2 BARABAI DARAT KALIMANTAN SELATAN TAHUN 2015 Azizaturridha, Aulia; Istiana, Istiana; Hayatie, Lisda
Berkala Kedokteran Vol 12, No 2 (2016)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v12i2.1864

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Abstract: Worm infection is an infectious disease caused by one or more intestinal parasitic worms from the class of intestinal nematodes. Worm infection can disruption of nutrients such as deficiency calories, protein, and blood loss. The aim of research is to know the effect of worm infection on nutritional status in SDN 2 Barabai Darats children South Kalimantan 2015. This research is an observational analytic with cross sectional approach. The total samples is 85 children from class 3 and 4, obtained by purposive sampling fit the inclusion criteria. Data collected by stool examination and measurement of nutritional status, the data were analyzed by Fischers Exact test. The results showed were 5,9% children with worm infections. Statistical analysis showed that there was not any effect of worm infection  on nutritional status based on BB/U (p = 1,000), based TB/U (p = 0,154), and based on BMI/U (p = 1,000). Conclusion from this research is not any effect of worm infection on nutritional status in children at SDN 2 Barabai Darat (p> 0,05). Keywords: worm infection, nutritional status, SDN 2 Barabai Darat Abstrak: Infeksi kecacingan adalah suatu penyakit infeksi yang disebabkan oleh satu atau lebih cacing parasit usus dari golongan nematoda usus. Infeksi kecacingan dapat menimbulkan gangguan zat gizi berupa kekurangan kalori, protein, dan kehilangan darah. Tujuan penelitian adalah untuk mengetahui pengaruh infeksi kecacingan terhadap status gizi pada anak di SDN 2 Barabai Darat Kalimantan Selatan tahun 2015. Jenis penelitian yang digunakan adalah penelitian observasional analitik dengan pendekatan cross sectional. Jumlah sampel sebanyak 85 anak dari kelas 3 dan 4, didapat secara purposive sampling  sesuai kriteria inklusi. Pengumpulan data dilakukan dengan pemeriksaan feses dan pengukuran status gizi, sedangkan analisis data dilakukan dengan menggunakan uji Fischers Exact. Hasil penelitian menunjukkan terdapat 5,9% anak yang positif terinfeksi cacing. Analisis statistik menunjukkan bahwa tidak terdapat pengaruh infeksi kecacingan terhadap status gizi berdasarkan BB/U (p=1,000), berdasarkan TB/U (p=0,154), dan berdasarkan IMT/U (p=1,000). Kesimpulan penelitian ini adalah tidak terdapat pengaruh infeksi kecacingan terhadap status gizi pada anak di SDN 2 Barabai Darat (p>0,05). Kata-kata kunci: kecacingan, status gizi, SDN 2 Barabai Darat
DERAJAT INFILTRASI LIMFOSIT PADA PENDERITA KANKER KOLOREKTAL SUB-TIPE ADENOKARSINOMA Imaduddin, Muhammad Sahal; Oktaviyanti, Ika Kustiyah; Istiana, Istiana
Berkala Kedokteran Vol 11, No 2 (2015): September 2015
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v11i2.141

Abstract

Cancer is the second leading cause of death which contributes 13% of deaths from a total of 22% of deaths from non-communicable diseases in the world. One contributor to the number of cancer deaths in the world is colorectal cancer. The prognosis of colorectal cancer depend on the stage of cancer at time of diagnosis. However, the prognosis of colorectal cancer can also be determined by looking at the degree of infiltration of lymphocytes in cancer. The purpose of this research is to find out the degree of lymphocytes infiltration in patients with colorectal cancer in Laboratory of Anatomical Pathology Banjarmasin from January to December 2013. The method uses descriptive research by observing the colorectal cancer tissues were obtained from the Laboratory of Pathology Banjarmasin. From a study of 32 samples, found the degree of mild lymphocytic infiltration occurred in 12 patients (37.5%), moderate lymphocytic infiltration occurred in 12 patients (37.5%), and severe lymphocyte infiltration occurred in 8 patients (25%). From this study, found that there are differences in the degree of infiltration of lymphocytes in patients with colorectal cancer. Keywords: Colorectal Cancer, Lymphocyte Infiltration, Prognosis
UJI EFEKTIVITAS BEBERAPA LARVASIDA TERHADAP LARVA NYAMUK Aedes aegypti DARI BANJARMASIN BARAT Istiana, Istiana
Jurnal Berkala Kedokteran Vol 11, No 1 (2015): Februari 2015
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v11i1.185

Abstract

Dengue Haemorrhagic Fever (DHF) is a dangerous infectious disease caused by the dengue virus and is transmitted through the bite of the mosquito Aedes aegypti. DHF control depends on controlling mosquitoes and larvae. Currently larvicidal control still uses temefos, although some studies have reported the presence of resistance. Larvicides that WHO recommended as a substitute temefos is permethrin. In addition there are some new larvicides derived from the class of insect growth regulator (IGR) which contain active pyriproksifen and active ingredients methopren. This study aims to determine the effectiveness of larvicides and effective concentration to kill 50% of larvae of Aedes aegypti from the sub Banjarmasin West. This study is an experimental study design with Posttest-Only Control Group Design with permethrin dose group was 0.0015 g / l; 0.0018 g / l; 0.002 g / l; 0.0022 g / l; 0.0025 g / l; and 0.0030 g / l, for pryriproksifen use dose groups of 0.5 ppm, 0.1 ppm, 0.05 ppm, 0.01 ppm, 0.008 ppm, 0.005 ppm, and methopren with dosis0 group g / l, 0, 0063 g / l, 0.0025 g / l, 0.005 g / l, 0.01 g / l, and 0.1 g / l. Each treatment group was exposed to larvae of Aedes aegypti larvae and change shape as well as the deaths were followed for 10 days. The results showed that the effective dose of permethrin kills 50% of larvae (Lethal Concentration / LC50) 24 hours ranged from 24 hour LC50 0.01439 - 0.01829 mg / l, with an average of 0.01671 mg / l and 24-hour LC99 ranged from 0.02856 - 0.03852 mg / l with an average of 0.03196 mg / l. This study showed that the larvae of Aedes aegypti in the district of West Banjarmasin are resistant to permethrin. As for pyriproksifen larvicides effectively killed larvae by 70% after seven days of exposure, and for larvicidal with active methopren killed 50% of larvae on the eighth day. This study shows that larviciding of IGR group can be an alternative in the area that has been declared resistant to abate as in the sub-district of West Banjarmasin. Keywords: effectiveness, permethrin, pyriproksifen, methopren, Aedes aegypti
Perbandingan Efektifitas Rapid Diagnostic Test (Rdt) Dengan Pemeriksaan Mikroskop Pada Penderita Malaria Klinis : Di Kecamatan Jaro Rakhman, M. Aulia; Istiana, Istiana; Al Audhah, Nelly
Jurnal Berkala Kedokteran Vol 9, No 1 (2013): April 2013
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v9i1.916

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ABSTRACT: Malaria is a disease caused by genus Plasmodium. Enforcement of the diagnosis malaria is microscopic examination of thick blood droplets and thin blood droplets and examination of Rapid Diagnostic Test (RDT). Gold standard for the diagnosis of malaria is microscopic examination. Rapid Diagnosis Test (RDT) is one alternative diagnostic tool in detecting Plasmodium quickly and doesn’t require special skill. The purpose of this study was to discover the effectiveness of Rapid Diagnostic Test (RDT) compared with microscopic examination in patient with clinical malaria in Jaro Sub-district. This study was a descriptive analytic study using the data of the result of malaria examination means of microscope examination and RDT on January – June 2012, with cross sectional approach. RDT examination result showed 98% sensitivity value, 100% specificity value, 100% positive predictive value and 98% negative predictive value compared with microscopic examination. Statistical test using Mc.Nemar test with 95% level of confidence interval p=0,125 (p>0,05). This show was no difference in the effectiveness of RDT examination and microscopic examination of patients with clinical malaria in Jaro Sub-district.Keywords: effectiveness, Rapid Diagnostic Test (RDT), microscopic examinationABSTRAK: Malaria adalah penyakit yang disebabkan oleh genus Plasmodium. Penegakkan diagnosis malaria adalah dengan pemeriksaan mikroskopis berupa tetesan darah tebal dan tetesan darah tipis serta pemeriksaan Rapid Diagnostik Test (RDT).  Gold standard untuk diagnosis malaria adalah dengan pemeriksaan mikroskopis. Rapid Diagnosis Test (RDT) merupakan salah satu alat diagnostik alternatif dalam mendeteksi Plasmodium secara cepat dan tidak memerlukan keterampilan khusus. Tujuan penelitian ini untuk mengetahui efektifitas Rapid Diagnostic Test (RDT) dibandingkan dengan pemeriksaan mikroskop pada penderita malaria klinis di Kecamatan Jaro. Penelitian ini merupakan penelitian deskriptif analitik menggunakan data hasil pemeriksaan malaria melalui pemeriksaan mikroskop dan RDT selama bulan Januari – Juni 2012 dengan pendekatan cross sectional. Hasil penelitian menunjukkan pemeriksaan RDT memiliki nilai sensitivitas 98%, spesifisitas 100%, nilai duga positif 100% dan nilai duga negatif 98% dibandingkan dengan pemeriksaan mikroskopis. Analisis uji statistik menggunakan uji Mc.Nemar dengan tingkat kepercayaan 95% didapatkan nilai p=0,125 (p>0,05)S. Hal ini menunjukkan tidak terdapat perbedaan efektifitas  pemeriksaan RDT dan mikroskopik pada penderita malaria klinis di Kecamatan Jaro.. Kata-kata kunci: efektifitas, Rapid Diagnostic Test (RDT), pemeriksaan  mikoskopisABSTRACT: Malaria is a disease caused by genus Plasmodium. Enforcement of the diagnosis malaria is microscopic examination of thick blood droplets and thin blood droplets and examination of Rapid Diagnostic Test (RDT). Gold standard for the diagnosis of malaria is microscopic examination. Rapid Diagnosis Test (RDT) is one alternative diagnostic tool in detecting Plasmodium quickly and doesn’t require special skill. The purpose of this study was to discover the effectiveness of Rapid Diagnostic Test (RDT) compared with microscopic examination in patient with clinical malaria in Jaro Sub-district. This study was a descriptive analytic stud
Hubungan Riwayat Malaria Sebelumnya dengan Kejadian Malaria Berdasarkan Hapusan Darah Pendonor di PT Pama Kecamatan Kintap Putera, Wahyu Aditia Husada; Al Audhah, Nelly; Istiana, Istiana
Jurnal Berkala Kedokteran Vol 10, No 1 (2014): Februari 2014
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i1.930

Abstract

ABSTRACT: Malaria is a disease that is caused by the Plasmodium genus and still become a problem around the world due to high mortality and morbidity. Several types of Plasmodium sp can be transmitted through blood transfusion. The aim of this study was to determine the relationship between history of previous malaria exposure with the event of malaria through donor’s blood smear at PT Pama Kintap subdistrict, Tanah Laut district. It was a survey of analytic-deskriptive study that performed on blood donors by using a questionnaire to see a history of previous malaria, and a smear of blood transfusion donors to see the Plasmodium sp in the blood transfusion. Sample of the research used total sampling method and gained 46 samples. The result was 4 (8.7%) had a previous history of malaria, and 2 (4.3%) was found some Plasmodium sp from their transfusion blood smear. Statistical analyisis used Fischer test, showed p value = 0.006 (p <0.05) which means there is a significant relation between a history of previous malaria exposure with the event of malaria through donor’s blood smear at malaria’s endemic region. Keywords: history of malaria, incident of malaria, blood donor ABSTRAK: Malaria adalah penyakit yang disebabkan oleh Plasmodium dan masih menjadi masalah di seluruh dunia karena angka morbiditas dan mortalitas yang tinggi. Beberapa jenis Plasmodium sp dapat ditularkan melalui transfusi darah. Penelitian ini bertujuan untuk mengetahui hubungan riwayat penyakit malaria sebelumnya dengan kejadian malaria berdasarkan hapusan darah pendonor di PT Pama kecamatan Kintap di kabupaten Tanah Laut. Penelitian ini bersifat survey analitic-descriptive yang dilakukan pada pendonor darah dengan menggunakan kuesioner untuk melihat riwayat malaria sebelumnya, dan hapusan darah transfusi pendonor untuk melihat adanya Plasmodium sp. Sampel penelitian menggunakan teknik total sampel dan mendapatkan 46 pendonor. Hasil penelitian menunjukkan bahwa 4 orang (8,7%) memiliki riwayat malaria sebelumnya, dan 2 orang (4,3%) ditemukan plasmodium dalam hapusan darah transfusinya. Analisis statistik menggunakan uji Fischer mendapatkan p value = 0,006 ( p < 0,05) yang menunjukkan ada hubungan yang bermakna antara riwayat malaria sebelumnya dengan kejadian malaria melalui hapusan darah transfusi pendonor. Kata-kata kunci: riwayat malaria, kejadian malaria, donor darah
Studi Interaksi Farmakodinamik Efek Analgesik Kombinasi Perasan Buah Mengkudu (Morinda citrifolia) dengan Parasetamol: Kajian terhadap waktu reaksi nyeri menggunakan metode hot plate pada mencit (Mus musculus) Wirasari, Firda; Bakhriansyah, Mohammad; Istiana, Istiana
Jurnal Berkala Kedokteran Vol 10, No 1 (2014): Februari 2014
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i1.927

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ABSTRACT: Mengkudu (Morinda citrifolia) has been proven in  possessing the analgesic effect. The similarity of analgesic activity of mengkudu and paracetamol enable the existence of analgesic effect interaction synergistically when they are both combined. The objective of this research is to find out the pharmacodynamic interaction between the juice of mengkudu and paracetamol. The research was an experimental research with posttest-only with control group design. The control group consists of 6 groups, and each group had 5 mice. The 1st group was given aquadest 0.5 ml; the 2nd group was given the juice of mengkudu 0.042 mg/g BB; the 3rd group was given paracetamol 0.065 mg/g BB; while the 4th , 5th, 6th groups were given the combination of mengkudu juice 0.042 mg/g BB and paracetamol with the dosages 0.01625 mg/g BB; 0.0325 mg/g BB; 0.065 mg/g BB, respectively. Treatments were given 10 minutes before mice were painly induced by using hot plate. The average of onset of pain for group I, II, III, IV, V, VI were 5.36; 8.28; 8.02; 9.67; 10.5 and 11.74 seconds, respectively. Statistical anaysis using Kruskal Wallis showed that there was significance difference among groups (p = 0.000) while the very potential effect was in group with paracetamol dosage on 0,065 mg/g BB. Based on this research, it can be concluded that there is sinergycal interaction between the combination of mengkudu juice with paracetamol on mice. Keywords : analgesic effect, mengkudu, paracetamol, onset of pain, synergycal interaction ABSTRAK: Mengkudu (Morinda citrifolia) telah terbukti memiliki efek analgesik. Kesamaan aktivitas analgesik buah mengkudu dan parasetamol memungkinkan adanya interaksi efek analgesik yang sinergis ketika keduanya dikombinasikan. Tujuan penelitian ini adalah untuk mengetahui interaksi farmakodinamik efek analgesik kombinasi perasan buah mengkudu dengan parasetamol. Penelitian ini bersifat eksperimental dengan pendekatan posttest-only with control group design, terdiri dari 6 kelompok. Setiap kelompok memiliki 5 ekor mencit. Kelompok I diberikan aquadest 0,5ml, kelompok II diberikan perasan buah mengkudu dengan dosis 0,042 mg/g BB, kelompok III diberikan parasetamol 0,065 mg/g BB sedangkan, kelompok IV, V, VI diberikan kombinasi perasan buah mengkudu 0,042 mg/g BB dan parasetamol dengan dosis masing-masing: 0,01625 mg/g BB; 0,0325 mg/g BB; 0,065 mg/g BB, diberikan 10 menit sebelum dilakukan induksi nyeri di atas hot plate. Rerata waktu reaksi nyeri mencit pada kelompok  I, II, III, IV, V, dan VI berturut-turut adalah 5,36; 8,28; 8,02; 9,67; 10,5 dan 11,74 detik. Hasil analisis statistik Kruskal-Wallis menunjukkan bahwa terdapat perbedaan yang bermakna antara berbagai kelompok dengan nilai p = 0,000, dengan dosis kelompok kombinasi yang paling potensial memberikan efek analgesik adalah kelompok dengan dosis parasetamol 0,065 mg/g BB. Berdasarkan penelitian ini dapat disimpulkan bahwa terdapat interaksi yang sinergis pada kombinasi perasan buah mengkudu dengan parasetamol pada mencit. Kata-kata kunci: efek analgesik, buah mengkudu, parasetamol, waktu reaksi, interaksi.
NILAI DIAGNOSTIK SKOR KLINIS DIBANDINGKAN DENGAN BIOPSI PATOLOGI ANATOMI DALAM MENDIAGNOSIS PASIEN KARSINOMA NASOFARING Rahmayanti, Dini Desviana; Oktaviyanti, Ika Kustiyah; Istiana, Istiana
Jurnal Berkala Kedokteran Vol 11, No 1 (2015): Februari 2015
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v11i1.188

Abstract

Nasopharyngeal malignancy is the most commonly found among head and neck malignancies. Generally, nasopharyngeal cancer, has a good prognosis if it is detected as soon as possible. It is very important to diagnose it earlier because survival rate can be longer if therapy is given early. This study aims to determine the diagnostic value of clinical scores compared with histopathology biopsy to diagnose nasopharyngeal carcinoma in patients of RSUD Ulin Banjarmasin in the period 2012-2014. Subjects of this study were patients of RSUD Ulin Banjarmasin Hospital which is suspected nasopharyngeal carcinoma, who have examined the clinical symptoms by history and physical examination, had been registered in the medical record, and had been examined with histopathology biopsy. Data of clinical examination and histopathology biopsy from each sampel were collected for clinical symptom scores were analyzed according to get sensitivity value, specifity value, positif predictive value, and negative predictive value.Total subject of this research was 30. In this study, a minimum clinical score to lead to a nasopharyngeal malignancy that if found clinical score of 4, with a sensitivity, specifity, positive predictive value , and negative predictive value of 75%, 83.33%, 94.74%, 45.45% respectively. Clinical characteristics have high sensitivity and specifity to diagnose nasopharyngeal carcinoma. Keywords: diagnostic value, clinical scores, nasopharyngeal carcinoma
Efektifitas Pyriproxyfen terhadap Larva Aedes aegypti yang Diambil dari Wilayah Banjarmasin Timur Akbar, Ali; Istiana, Istiana; Al Audhah, Nelly
Jurnal Berkala Kedokteran Vol 10, No 1 (2014): Februari 2014
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i1.928

Abstract

ABSTRACT: Dengue Haemorraghic Fever disease (DHF) is dangerous contagious disease which is caused by dengue virus which is brought by Aedes aegypti mosquito. Controling DHF depends on the control of the mosquito and its larvae. One of alternative larvacide that can control Aedes aegypti larvae is larvacide with active ingredient pyriproxyfen as Insecth Growth Regulator (IGR) which does not influece the hygiene of water, safety and does not increase the resistancy. The purpose of the study is to study and calculate efficacy of an IGR pyriproxyfen against Aedes aegypti larvae which was only collected from East Banjarmasin. The research is an experimental research that used seven kind dozes of IGR: follows 0,1 ppm, 0,05 ppm, 0,01 ppm, 0,008 ppm, 0,005 ppm, 0,003 ppm, and control. Each doze used four replications. The research results showed that IGR was effective to kill more than 70% larvae after seven days. The results of probit analysis were 0,001 ppm ana 0,065 ppm to kill 50% and 90% larvae. Keywords: Dengue Haemorraghic Fever, pyriproxyfen, Aedes aegypti ABSTRAK: Penyakit Demam Berdarah Dengue (DBD) adalah penyakit menular berbahaya yang disebabkan oleh virus dengue yang dibawa oleh nyamuk Aedes aegypti. Pengendalian DBD bergantung pada pengendalian nyamuk dan larvanya. Salah satu larvasida alternatif yang dapat digunakan untuk mengendalikan larva nyamuk Aedes aegypti adalah larvasida yang berbahan aktif pyriproxyfen dan berasal dari golongan Insect Growth Regulator (IGR) yang tidak mempengaruhi kebersihan air, aman, dan tidak meningkatkan resistensi. Penelitian ini bertujuan untuk mengetahui dan menghitung efikasi IGR berbahan aktif pyriproxyfen terhadap larva Aedes aegypti yang berasal dari Kecamatan Banjarmasin Timur. Penelitian ini merupakan penelitian eksperimental yang menggunakan tujuh macam dosis 0,1 ppm, 0,05 ppm, 0,01 ppm, 0,008 ppm, 0,005 ppm, 0,003 ppm, dan kontrol. Setiap dosis menggunakan empat kali pengulangan. Hasil penelitian menunjukan bahwa IGR efektif untuk membunuh 70% larva uji setelah tujuh hari pemaparan. Berdasarkan analisis probit dosis yang diperlukan untuk membunuh 50% (LC50) dan 90%(LC90) larva uji adalah berturut-turut sebesar 0,001 ppm dan 0,065 ppm. Kata kunci : Demam Berdarah Dengue,  pyriproxyfen, Aedes aegypti