Dian Indriyani
Bagian Ilmu Kesehatan Kulit dan Kelamin, Fakultas Kedokteran Universitas Padjadjaran, Rumah Sakit Hasan Sadikin

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Efikasi Terapi Kombinasi Salep Kalsipotriol 0,005% dan Klobetasol Propionat 0,05% Dibanding Klobetasol Propionat 0,05% pada Psoriasis Vulgaris

Majalah Kedokteran Bandung Vol 1, No 42 (2010)
Publisher : Majalah Kedokteran Bandung

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Abstract

Psoriasis adalah penyakit eritropapuloskuamosa kronik residif. Obat yang paling sering digunakan untuk terapi penyakit ini adalah kortikosteroid topikal, tetapi penggunaan jangka panjang dapat menyebabkan berbagai efek samping. Kalsipotriol merupakan obat topikal selain kortikosteroid yang memiliki efek samping yang lebih ringan. Tujuan penelitian ini adalah untuk membandingkan skor psoriasis area and severity index (PASI) sebelum dan sesudah pengobatan dengan kombinasi salep kalsipotriol 0,005% dengan salep klobetasol propionat 0,05% dan monoterapi salep klobetasol propionat 0,05% pada penderita psoriasis vulgaris. Skor psoriasis area severity index (PASI), digunakan untuk mengukur berat ringannya psoriasis dan mengevaluasi perbaikan lesi. Desain penelitian adalah uji klinik dengan rancangan acak secara double blind. Uji Mann-Whitney dan Wilcoxon digunakan untuk menganalisis data skor PASI sebelum dan sesudah pengobatan. Penelitian dilakukan di poliklinik I.K. Kulit danKelamin RS. Hasan Sadikin Bandung dari bulan November 2007- Januari 2008 dengan subjek penelitian sebanyak 44 orang yang dibagi dalam dua kelompok. Derajat keparahan penyakit dinilai dengan skor PASI yang dinilai sebelum, satu minggu, dan dua minggu setelah pengobatan. Kesimpulan: Penggunaan terapi kombinasi salep kalsipotriol 0,005% dan klobetasol propionat 0,05% selama dua minggu memiliki efikasi yang lebih baik dibandingkan monoterapi salep klobetasol propionat 0,05%, secara statistik sangat bermakna (p<0,001).Efficacy Combination Therapy of 0.005% Calcipotriol and 0.05%Clobetasol Propionat Compared to 0.05% Clobetasol Propionat Ointment in Psoriasis VulgarisPsoriasis is a chronic relapsing erythropapulosquamous skin disease. Topical corticosteroid is the most common treatment for psoriasis, but it can cause many side effect on longterm used. Calcipotriol ointment is the other topical treatment for psoriasis and has minimal side effect. The study was a double blind randomized clinical trial, compared psoriasis area and severity index score before and after treatment combination therapy of 0.005% calcipotriol ointment 0.05% and clobetasol propionat ointment with 0.05% clobetasol propionat alone. Psoriasis area severity index (PASI) score was used to evaluate severity degree and imprvoment of psoriasis. Mann-Whitney and Wilcoxon test were used for statistical analysis of PASI score before and after treatment. Study was conducted at Dermatology and Venereology outpatient Department of Hasan Sadikin Hospital Bandung period November 2007 to January 2008 with fourty four psoriasis vulgaris patients were enrolled in this study, divided into two groups. The assesment of the severity of skin lesions psoriasis area and severity index was performed at baseline, after one week and two weeks treatment. Conclusion: the use of daily 0.005% calcipotriol ointment combined with 0.05% clobetasol propionate

Taksiran Akumulasi Biomassa atas Permukaan pada Eksperimen Restorasi Lahan Gambut Bekas Terbakar, Area Transisi Cagar Biosfer Giam Siak Kecil-Bukit Batu, Riau, Sumatera Indonesia

Jurnal Riau Biologia Vol 1, No 1 (2016)
Publisher : Jurusan Biologi FMIPA Universitas Riau

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Abstract

The Giam Siak Kecil-Bukit Batu Biosphere Reserve was managed by zonation as a approach for multibenefitof management goals. This Bioshere Reserve has a fairly high carbon stock stored in its naturalpeat swamp forest ecosystems. Nevertheless, the condition of the peat swamp forest in the BiosphereGiam Siak Kecil-Bukit Batu currently has been destructed, especially in the buffer and transition zones.The threats of protected areas are not only coming from forest fire factors, but also from encroachmentand illegal logging. Therefore, it requires a recovery effort. This research aims to determine the survivalrate and to estimate the above ground biomass accumulation of the main tree species of peat swamp forestthat used to restore the burnt peat. The estimated total biomass accumulation on the surface was measured using allometric equations. Result of this research proved that Jelutung tree (Dyera polyphylla) has thebest survival rate among the trees (98%), while banana tree (Mezzettia parviflora) has lower survival rate( 35%). The highest total biomass accumulation was found in Jelutung (Dyera polyphylla) (499.015kg/ha/year, while the lowest total biomass accumulation was found in Meranti batu (Shorea uliginosa)(88.867 kg/ha/year). A total of nine pioneer species were identified i.e. Tenggek burung (Euodia sp),kayu ara (Ficus sp), mahang (Macaranga triloba), karet (Havea brasiliensis), sendayan (Scleriasumatrensis), alang-alang (Imperata cylindrica), senduduk (Melastoma malabathricum), paku-pakuan(Neprolepis hirsutula) and rumput teki (Cyperus rotundus). The total biomass accumulation of earlysuccession in all types of vegetation pioneer is 338,91 kg/ha.Key words: Above Ground Biomass Accumulation, restoration, vegetasion succession, burned peatland,Survival Rate.

SEKULARISME DAN ISU-ISU GERAKAN UMAT ISLAM

Nurani: Jurnal Kajian Syariah dan Masyarakat Vol 17 No 2 (2017): Nurani
Publisher : Fakultas Syariah dan Hukum Universitas Islam Negeri Raden Fatah Palembang

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Abstract

In its history, politically, liberalism of Islam accepts deep momentum during Sultanate-Autonomy in Turkey, where Islamic countries, especially Turkey and Egypt, which had got in touch with western world, had big influences toward Islamic societies’ attitude. This influence made the Turkish and the Egyptian understands rigid. Islamic scholars of law seem confused to see new thing in Islamic societies. A case will directly be instructed “illegal” or haram if the case itself cannot be found in the school of Hanafi’s classical books. Then, this paper is intended to contribute some points of view of this school by means of answering some main questions about the truth of Islamic liberal considered as a secular movement under the guise of Moslem, the truth of the discourse of Islamic liberalism presents the past for the sake of modernization and the truth of Islamic liberalism that is irrelevant to the Indonesian culture.