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MODEL MATEMATIS PENJERAPAN KADMIUM DALAM AIR PADA ADSORBEN KULIT NANGKA Anita, Fransisca; Indah, Adelia; Inayati, Inayati
PROSIDING SENATEK FAKULTAS TEKNIK UMP 2015: PROSIDING SENATEK TAHUN 2015, 28 November 2015
Publisher : PROSIDING SENATEK FAKULTAS TEKNIK UMP

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Banyak industri berkembang di jaman sekarang, seperti industri pabrik pembuatan baterai, plastik, dan pigmen. Salah satu dampak dari limbah industri –industri tersebut adalah adanya pencemaran air oleh logam berat, misal logam kadmium yang banyak menimbulkan masalah sehingga perlu dikurangi jumlahnya dalam air. Untuk meminimalkan jumlah logam berat dalam air diperlukan sebuah proses pengolahan air dengan metode adsorpsi. Metode adsorpsi dapat dilakukan menggunakan media seperti zeolit, karbon aktif dan adsorben lainnya. Pengaktifan bahan dilakukan dengan menggunakan larutan NaOH 2% dengan cara memvariasi  waktu aktivasi (0 jam, 12 jam, 24 jam, 36 jam, dan 48 jam), pH larutan sampel (2,4,6, dan 8), dan waktu kontak (10 menit,20 menit, 30 menit, 40 menit, dan 50 menit). Tujuan dari penelitian ini menentukan model matematis yang terbaik untuk proses adsorpsi menggunakan limbah kulit nangka. Konsentrasi awal cadmium  sebesar 2,5 ppm. Analisis konsentrasi cadmium akhir dari sampel menggunakan AAS. Berdasarkan hasil percobaan sesuai dengan persamaan isotherm Langmuir dengan nilai konstanta a sebesar 44,56 dan konstanta b sebesar 0,00956.Kata kunci: adsorben, penjerapan kadmium, kulit nangka, model isotherm adsorpsi
Kutu Kebul: Hama Kedelai yang Pengendaliannya Kurang Mendapat Perhatian Marwoto, Marwoto; Inayati, Inayati
Buletin Iptek Tanaman Pangan Vol 6, No 1 (2011): Juni 2011
Publisher : Puslitbang Tanaman Pangan

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Abstract

Salah satu gangguan dalam meningkatkan produksi kedelai adalah serangan hama kutu kebul (Bemisia tabaci). Tanaman kedelai yang terserang kutu kebul daunnya menjadi keriting dan apabila serangan parah disertai dengan infeksi virus, daun menjadi keriting berwarna hitam dan pertumbuhan tanaman terhambat. Ekskreta kutu kebul menghasilkan embun madu yang merupakan media tumbuh cendawan jelaga, sehingga tanaman terserang tampak berwarna hitam. Kehilangan hasil akibat serangan hama kutu kebul dapat mencapai 80%, bahkan pada serangan berat dapat menyebabkan puso (gagal panen). Pengendalian kutu kebul pada tanaman kedelai oleh petani sering mengalami kegagalan. Untuk mengantisipasi serangan hama ini perlu diketahui biologi, tingkat kerusakan, kehilangan hasil, dan cara pengendalian di tingkat petani sebagai dasar untuk menyusun strategi pengendalian yang tepat. Pengendalian hama kutu kebul dapat dilakukan dengan pendekatan Pengendalian Hama Terpadu (PHT) menggunakan komponen pengendalian yang kompatibel termasuk waktu tanam, varietas tahan, musuh alami, aplikasi pestisida berlandaskan pada azas ekologi dan ekonomi. Dengan pendekatan PHT diharapkan pengendalian kutu kebul lebih efektif.
EVALUATION ON THE ANTIHYPERTENSIVE THERAPY USAGE ON BLOOD PRESSURE PREDIALYSIS IN OUTPATIENTS WITH END STAGE RENAL DISEASE (ESRD) RECIVING ROUTINE HEMODIALYSIS AT PKU MUHAMMADIYAH HOSPITAL YOGYAKARTA Fitriani, Fitriani; Nugroho, Agung Endro; Inayati, Inayati
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 1, No 3
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

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Hypertension and chronic kidney disease (CKD) are the two kinds of disease that are related each others. The prevalence of hypertension is estimated occur in 80% of the hemodialysis population. This research aims to determine the relationship between the compliance levels of patients in antihypertensive medication on blood pressure predialysis This research is conducted by using a descriptive prospective observational study. Data analysis was performed to determine the profile of antihypertensive therapy use, antihypertensive medication therapy outcomes profile, and the influence of the patients’ compliance level in antihypertensive medication. The patient compliance level in taking antihypertensive drugs is assessed by questionnaire of Modified Morisky Scale (MMS). Based on the research results,, the antihypertensive profile used was CCBs system (32,91%), loop diuretics (23,42%), AIIRA (15,82%), central α agonists (12,66%), ACEI (12,03 %), and β blockers (3,16%). Antihypertensive therapies applied single and combination therapy. The most used monotherapy is CCBs (3,70%), whereas the most used combination are combination of the class of CCBs, AIIRA, and loop diuretics (16.67%). The outcomes profile of antihypertensive medication therapy based on the measurement results of pre-dialysis blood pressure are target of pre-dialysis blood pressure (<140/90 mmHg) can only be achieved by 3 patients, 2 patients are the compliance patients with the right choice and appropriate dose of antihypertensive therapy and 1 patient is a non-adherent patient with incorrect type and inappropriate doses of antihypertensive therapy. Most of hemodialysis patients have isolated systolic hypertension. The influence of the patients’ compliance level in antihypertensive medication towards the blood pressure control of pre-dialysis outpatients, there are 19 patients (35,19%) in the category of non-adherent patients with a mean blood pressure is 168,40/ 91,95 mmHg, and 35 patients (64,81%) in the category of adherence with a mean blood pressure is 165,60/ 87,77 mmHg. Keywords : digoxin, heart failure, renal dysfunction, clinical outcome. 
THE ANALYSIS OF THE ANTIBIOTIC USE TOWARDS SURGICAL SITE INFECTION ON THE PATIENTS OF GASTROINTESTINAL SURGERY AT PKU MUHAMMADIYAH HOSPITAL YOGYAKARTA Faridah, Imaniar Noor; Andayani, Tri Murti; Inayati, Inayati
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 2, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

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Surgical Site Infection / SSI is the result of the contamination of bacteria which enter the body as the surgery is in progress. High risk of Surgical Site Infection occurs in gastrointestinal surgery and is influenced by some characteristics, such as the use of antimicrobial prophylaxis. This research was aimed at identifying the use of antibiotics, identifying the percentage of the occurrence of Surgical Site Infection on the patients of gastrointestinal surgery. The research is a cross sectional research conducted prospectively at PKU Muhammadiyah Hospital Yogyakarta. The research subjects were all inpatients suffering gastrointestinal surgery and using antibiotic during the period of January until March 2012, and there are 68 patients fulfill the inclusion criteria. The inclusion criteria of the research is inpatient suffering gastrointestinal surgery, surgical site is visible, and use antibiotic for preventing Surgical Site Infection. Data that were analyzed comprised the use pattern of prophylactic antibiotics both perisurgery and post-surgery, and the analysis of the occurrence of Surgical Site Infection. The result of the research indicated that prophylactic antibiotics that was given to 14 patients with the most frequently used antibiotic was ceftriaxone (7.35%); perisurgical antibiotics that was given to 16 patients with the most frequently used antibiotics was the combination of ceftriaxone and metronidazole (8.82%), post-surgical antibiotics was given to all patients intravenously or orally in which the most frequently used intravenous antibiotics was ceftriaxone (30.88%) and the most frequently used oral was the quinolones (33.33%) and the most frequently used antibiotic type was cefadroxil (25%). The Surgical Site Infection occurred to 2 patients (2.94%) in contaminated surgery, with the comorbidity of non-diabetic, and they did not use prophylactic antibiotics.Key words: gastrointestinal surgery, occurrence of surgical site infection, prophylactic antibiotics
EVALUATION ON THE ANEMIA THERAPY USAGE TOWARD CHRONIC KIDNEY DISEASE ASKES PATIENTS RECEIVING REGULAR HAEMODIALYSIS THERAPY AT PKU MUHAMMADIYAH HOSPITAL YOGYAKARTA Hidayati, Hidayati; Nugroho, Agung Endro; Inayati, Inayati
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 1, No 3
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

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Abstract

Anemia is mostly associated with chronic kidney disease (CKD) patients. Anemia in CKD patients occurs due to the lack of erythropoietin. Low hemoglobin concentration relates to bad clinic outcome toward CKD patients. Epoetin therapy for CKD patients has been clinically confirmed to improve the quality of life and lower the morbidity and mortality rate. This research was intended to investigate the anemia profile therapy, adjuvant per-oral anemia therapy adherence profile and the effect of adjuvant per-oral anemia therapy adherence toward achievement target of anemia therapy using epoetin in CKD Askes patient receiving regular haemodialysis therapy at PKU Muhammadiyah Hospital Yogyakarta. The research was conducted using observational study design with prospective data collection, then the data were analyzed in order to know the success of anemia primary therapy via epoetin and adjuvant per-oral anemia therapy. The success of therapy were measured based on National Kidney Foundation-Kidney Disease Outcomes Quality Initiative (NKF-K/DOQI), 2006, while adherence was measured via Modified Morisky Scale (MMS) questionnaire. Based on the research, epoetin used in this research was epoetin alpha and beta, each 69.05% and 30.95%. Adjuvant per-oral anemia therapy used in this research was combined folic acid, iron and vitamin B complex (82.05%); folic acid (10.26%); combined folic acid and vitamin B-complex (7.69%). Groups of epoetin sub dose with unachieved target and epoetin complete dose with unachieved target were 64.29% and 21.41%; Groups of epoetin sub dose with achieved target and epoetin complete dose with achieved target showed similar results 7.14%. The adherence profile of adjuvant per-oral anemia therapy were consisted of obedient patients and disobedient patients, each 69.23% and 30.77%. Askespatient adherence in using adjuvant per-oral anemia therapy, in this research, was able to assist the achievement of epoetin therapy target. Keywords : Anemia, adherence, chronic kidney disease, regular haemodialysis, epoetin, adjuvant per-oral anemia
THE EFFECTIVENESS AND COST ANALYSIS OF ZINC TREATMENT ON THE CHILDREN WITH ACUTE DIARRHEA IN PKU MUHAMMADIYAH YOGYAKARTA HOSPITAL IN 2011 Khoirunnisa, Sudewi Mukaromah; Andayani, Tri Murti; Inayati, Inayati
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 2, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

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Diarrhea is the second leading cause of death among children in the world and medical cost to deal with diarrhea is significantly high. WHO and UNICEF recommend the use of zinc to treat diarrhea on children. This research was aimed to assess of diarrhea the influence of giving zinc supplement on the duration, length of stay and frequency, and to identify the amount of direct medical cost borne by the patient who used utilizing zinc in order to treat diarrhea. This research was conducted with non-experimental descriptive design. Data were taken retrospectively from medical record and financial office of PKU Muhammadiyah Yogyakarta Hospital. The research subjects were child patients aged 1 - < 15 years old suffering from acute diarrhea, used antibiotic, had no other diseases, and treated as inpatient during the period of January 1 until December 31st 2011. The number of samples that met the inclusion criteria were 67 patients for each zinc and control group. The data were analyzed based on the characteristics of patients, diarrhea duration in the hospital, length of stay, diarrhea frequency and amount of medical cost. Data were analyzed descriptive quantitatively and statistically to compare the means of variables between both groups. The research result indicated that the group receiving zinc had shorter diarrhea duration of ±0.45 day (p<0.05), shorter length of stay of ±0.09 day (p>0.05), and lower diarrhea frequency from the second to the fourth day of the treatment (p<0.05). In regard to cost analysis, the total medical cost of zinc group was lower than that of control group (p<0.05) accounts for IDR. 1,155,407. However, it could not be concluded that the use of Zinc was effective. The use of zinc was effective in treating acute diarrhea on inpatients children.Keywords: zinc, acute diarrhea, effectiveness, direct medical cost
Analisis Outcome Pasien Post Stroke Hyperglycemia Tanpa Terapi Antihiperglikemia Maziyyah, Nurul; Sugiyanto, Sugiyanto; Inayati, Inayati
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 13 No. 01 Juli 2016
Publisher : Fakultas Farmasi, Universitas Muhammadiyah Purwokerto

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Abstract

ABSTRAK Poststroke Hyperglycemia (PSH) merupakan kejadian peningkatan kadar gula darah yang signifikan setelah terjadinya serangan stroke. Kejadian PSH telah diketahui dapat menimbulkan dampak yang buruk bagi pasien. Saat ini rekomendasi terapi untuk pasien PSH adalah terapi berbasis insulin. Namun pendekatan di klinik pada kenyataannya masih berbeda–beda, salah satunya adalah tidak diberikannya terapi antihiperglikemia pada pasien-pasien tertentu. Penelitian ini bertujuan untuk mengetahui gambaran outcome pada pasien PSH yang tidak mendapatkan terapi antihiperglikemia di rumah sakit. Penelitian ini menggunakan rancangan non eksperimental secara deskriptif-analitik. Data diperoleh secara retrospektif dengan menelusuri rekam medik pasien stroke yang dirawat inap pada periode Oktober 2011–Oktober 2012 di sebuah rumah sakit swasta di Yogyakarta. Pasien dinyatakan mengalami PSH jika kadar gula darah pasien saat masuk rumah sakit ≥140 mg/dL. Pasien PSH dikelompokkan berdasarkan riwayat diabetes mellitus (DM) sebelum stroke. Analisis dilakukan terhadap outcome pasien PSH yang tidak diberikan terapi antihiperglikemia berupa kadar gula darah pasien setelah ±24 jam di rumah sakit dan kondisi pasien di akhir perawatan di rumah sakit. Hasil penelitian menunjukkan bahwa sebagian besar (96,88%) pasien PSH yang tidak mendapatkan terapi antihiperglikemia adalah pasien tanpa riwayat DM dengan baseline kadar gula darah saat masuk rumah sakit berada pada rentang 140–180 mg/dL (71,88%). Gambaran kadar gula darah setelah ± 24 jam perawatan memperlihatkan bahwa 55,38% pasien tidak terekam kadar gula darahnya sementara 33,85% mengalami penurunan dan sisanya 10,77% mengalami peningkatan kadar gula darah. Kondisi pasien di akhir perawatan sebagian besar membaik (68,75%), namun terdapat 29,69% pasien yang meninggal selama perawatan. Outcome yang beragam pada pasien PSH perlu menjadi perhatian khususnya oleh para klinisi, agar kadar gula darah pasien dapat terekam dengan jelas selama fase akut stroke di rumah sakit untuk mengambil keputusan yang tepat terkait terapi pasien. Hal ini untuk menghindari dampak buruk dari kondisi hiperglikemia (termasuk tingkatan hiperglikemia ringan) pada pasien stroke. Kata kunci: poststroke hyperglycemia, outcome, antihiperglikemia. ABSTRACT Poststroke Hyperglycemia (PSH) occurs when there is a significant increase in blood glucose level after stroke attack. PSH has been known to cause various negative effects on stroke patients. PSH therapy recommendation from various guidelines nowadays is insulin-based therapy. On the other hand, many clinicians use various approaches in overcoming this condition, one of which is not treating PSH patients (probably specific PSH patients). This study aims to describe outcomes in PSH patients untreated with antihyperglycemia agent. This study uses a non experimental design with a descriptive and analytical approach. Data was obtained retrospectively through medical records of stroke patients hospitalized from October 2011–October 2012 in a private hospital in Yogyakarta. Patients were stated as PSH if the admission blood glucose level was ≥140 mg/dL. PSH patients were classified based on their history of diabetes mellitus (DM); diabetic or non diabetic. Outcome in untreated PSH patients was described through blood glucose level after ±24 hours hospitalized and their final condition in the hospital. The result of this study showed that most of untreated PSH patients (96.88%) were non diabetic patients with a baseline of 140–180 mg/dL on their admission blood glucose level (71.88%). Outcome of blood glucose level after ±24 hours of hospitalization revealed 55.38% of the patients didn’t have their blood glucose level recorded, while 33,85% had a decrease in glucose level and the remaining 10.77% had a rise in their glucose level. Patients’ final conditions were mostly getting better (68.75%), but there were 29.69% of patients who died during hospitalization. The various outcomes seen in untreated PSH patients should give awareness for clinicians to have a complete record on patients’ blood glucose level throughout the acute phase of stroke in order to decide for the best treatment. Hence, negative effect following hyperglycemia condition (including mild hyperglycemia) in stroke patients could be prevented.. Key words: poststroke hyperglycemia, outcome, antihyperglycemia.
Analisis Sistem Distribusi Obat di Instalasi Farmasi Rawat Inap Jogja International Hospital Wijayanti, Tri; Danu, Sulanto Saleh; Inayati, Inayati
Jurnal Farmasi Indonesia Vol 8 No 1 (2011): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

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Penelitian ini bertujuan untuk mengetahui sistem distribusi obat yang telah dijalankan di instalasi rawat inap Jogja International Hospital serta mengetahui faktor-faktor yang mempengaruhi sistem distribusi obat di Instalasi rawat inap Jogja International Hospital. Penelitian ini menggunakan metode observasional dengan rancangan case study dan bersifat deskriptif-analitik dengan pendekatan kualitatif. Data diambil secara retrospektif dan prospektif, dilakukan dengan wawancara mendalam dan mengumpulkan data dari dokumen pendistribusian obat serta survei resep di Instalasi Farmasi Rawat Inap Rumah Sakit Jogja International Hospital (JIH). Berdasarkan penelitian ini, sistem distribusi obat ke pasien yang digunakan di JIH adalah UDDS, individual prescription, floorstock dan emergency kit. Penggunaan sistem distribusi UDDS di instalasi rawat inap banyak memberikan keuntungan terutama bagi pasien sebagai konsumen dan sistem ini dapat berjalan baik dengan dukungan manajemen yang baik dan terpadu dimana dalam hal ini di JIH telah berjalan dengan bak. Pengelolaan obat-obat floorstock dan emergency kit yang ada di setiap nurse station dilakukan petugas perawat yang dipantau penggunaannnya oleh petugas farmasi. Sedangkan untuk instalasi rawat jalan, digunakan sistem individual prescription. Sistem pendistribusian obat yang digunakan di instalasi farmasi rawat inap jogja international hospital adalah unit dose sispensing system. Penggunaan UDDS di JIH masih belum memiliki kendala dikarenakan jumlah pasien dantenaga kefarmasian masih mencukupi.