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Journal : JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)

EVALUATION ON THE ANEMIA THERAPY USAGE TOWARD CHRONIC KIDNEY DISEASE ASKES PATIENTS RECEIVING REGULAR HAEMODIALYSIS THERAPY AT PKU MUHAMMADIYAH HOSPITAL YOGYAKARTA Hidayati, Hidayati; Nugroho, Agung Endro; Inayati, Inayati
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 1, No 3
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

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Abstract

Anemia is mostly associated with chronic kidney disease (CKD) patients. Anemia in CKD patients occurs due to the lack of erythropoietin. Low hemoglobin concentration relates to bad clinic outcome toward CKD patients. Epoetin therapy for CKD patients has been clinically confirmed to improve the quality of life and lower the morbidity and mortality rate. This research was intended to investigate the anemia profile therapy, adjuvant per-oral anemia therapy adherence profile and the effect of adjuvant per-oral anemia therapy adherence toward achievement target of anemia therapy using epoetin in CKD Askes patient receiving regular haemodialysis therapy at PKU Muhammadiyah Hospital Yogyakarta. The research was conducted using observational study design with prospective data collection, then the data were analyzed in order to know the success of anemia primary therapy via epoetin and adjuvant per-oral anemia therapy. The success of therapy were measured based on National Kidney Foundation-Kidney Disease Outcomes Quality Initiative (NKF-K/DOQI), 2006, while adherence was measured via Modified Morisky Scale (MMS) questionnaire. Based on the research, epoetin used in this research was epoetin alpha and beta, each 69.05% and 30.95%. Adjuvant per-oral anemia therapy used in this research was combined folic acid, iron and vitamin B complex (82.05%); folic acid (10.26%); combined folic acid and vitamin B-complex (7.69%). Groups of epoetin sub dose with unachieved target and epoetin complete dose with unachieved target were 64.29% and 21.41%; Groups of epoetin sub dose with achieved target and epoetin complete dose with achieved target showed similar results 7.14%. The adherence profile of adjuvant per-oral anemia therapy were consisted of obedient patients and disobedient patients, each 69.23% and 30.77%. Askespatient adherence in using adjuvant per-oral anemia therapy, in this research, was able to assist the achievement of epoetin therapy target. Keywords : Anemia, adherence, chronic kidney disease, regular haemodialysis, epoetin, adjuvant per-oral anemia
Co-Authors A, Agung Agoes Soehianie Agung Endro Nugroho Agus Prasetyo Alexander A. Iskandar A. Iskandar Alwafi, Iffa Arifuddin Arifuddin Asbah, Asbah Asmawit Asmawit, Asmawit Asmawit, Asmawit Astuti Wijayanti, Astuti Aurum, Jati Bakar, Ali Abu Bambang Setiaji Budi, Agnes Cahyani, Rani Candra Kurniawan Christianingrum Christianingrum, Christianingrum Darma, Azri Desi Purnamasari Didiek Herhady Dodi Ramdani, Dodi Duwi Agustina, Duwi Ernawati Ernawati Erni Suryandari, Erni Fadil Oenzil Fahrudin Fahrudin Fara, Lintan Farid Salahudin, Farid Farida, Camellia Fatni Mufit Ferry Sudarto, Ferry Fitri Jayanti, Fitri Fitriana Djafar, Fitriana Gambiro Gambiro, Gambiro Geubrina, Misla Gusrawati, Rina Hafni Bachtiar Hartono Hartono Hastuti, Ening Sry Helmi Arifin Humaira Humaira Husada, Sarif Ilham Ilham Inayati Inayati Isran, Isran istiqomah istiqomah Jejem Mujamil, Jejem Juniana, Nur Kuswardani Kuswardani, Kuswardani Lukman Lukman Masril Masril Maya Yusnita, Maya Mayasari Mayasari, Mayasari Mayefis, Delladari Miftahus Surur, Miftahus Mohamad Rusdi Hidayat, Mohamad Rusdi Mohammad Rusdi Hidayat, Mohammad Rusdi Muhammad Dani Supardan Muhammad Ikhsanudin, Muhammad Murniati, Asih Mustafa, Dian PW Najemi, Chairin Nana Supriyatna, Nana Ningsih, Ica Nursari, Nursari Pasaribu, Sumihar Praba Ginandjar Pramono Putro Utomo, Pramono Putro Prianti, Anna Puji Hariati Winingsih, Puji Hariati Qadariah, Lelly Rahayu, Gustria Rahmaniah, Rima RAVEINAL RAVEINAL Reni Marlina Riri Jonuarti Ristiyanti, Septi Rusnaini Rusnaini Saleh, Eniza Sandi, Indah Maydila Saputro, Nurhadi Semiyatun, Semiyatun Septi Ambarwati, Septi Sigit Sujatmika, Sigit Sopiah, Sopiah Sri Hainil, Sri Sri Rinanti Susilowati Sukma Budi Ariyani, Sukma Budi SUMADI SUMADI Sumar, Sumar Susanti Susanti Suwoto Suwoto Syafruddin Ilyas Tahrir Aulawi Tias Ernawati, Tias Veator Renyaan, Veator Wahyuni Satria Dewi, Wahyuni Satria Wahyuni, Eka Dwi Widiani, Arovah Widowati Pusporini, Widowati Yenni Darvina Yuli Prihatni Yulia Jamal Yurnetti, Yurnetti Yuvia, Yuvia Zain, Isna Zainap, Siti Zakirman, Zakirman Zakiya, Zara Zuindra, Zuindra