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All Journal Jurnal Kedokteran Diponegoro BAHASA DAN SASTRA Medika Tadulako Sari Pediatri Jurnal Luka Indonesia Tasamuh: Jurnal Studi Islam Journal of Tropical Pharmacy and Chemistry
Hardian Hardian
Staf pengajar Bagian Fisiologi FK UNDIP, Jl. Dr. Sutomo No.18 Semarang
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences

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Journal : Jurnal Kedokteran Diponegoro

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HUBUNGAN ANTARA JENIS ANTIPIRETIKA YANG DIGUNAKAN DENGAN MANIFESTASI PERDARAHAN PADA ANAK YANG MENDERITA DEMAM BERDARAH DENGUE Rachmawati, Elfian; Arkhaesi, Nahwa; Hardian, Hardian
MEDIA MEDIKA MUDA 2012:MMM VOLUME 1 NUMBER 1 YEAR 2012
Publisher : MEDIA MEDIKA MUDA

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Abstract

Latar Belakang: Demam Berdarah Dengue (DBD) merupakan suatu penyakit infeksi akut yang sering menimbulkan wabah terutama pada golongan anak – anak. Gejala klinis demam yang muncul pada fase awal hampir sama denganpenyakit infeksi lain, sehingga beberapa ibu rumah tangga memberikan obat penurun panas (antipiretika) kepada anak mereka sebagai penanganan pertama tanpa dilatar belakangi oleh pengetahuan yang cukup tentang penggunaan jenis antipireika secara tepat dan diduga mampu memperburuk manifestasi perdarahan.Tujuan: Membuktikan hubungan antara jenis antipiretika yang digunakan dengan manifestasi perdarahan pada anak DBD.Metode : Penelitian yang dilakukan merupakan penelitian observasional dengan pendekatan studi cross sectional. Pengambilan sampel dilakukan melalui metode consecutive sampling di Departemen Ilmu Kesehatan Anak RSUP Dr. Kariadipada bulan Maret 2012 sampai dengan Juni 2012. Data tentang penggunaan jenis antipiretika diperoleh melalui wawancara kuesioner kepada ibu atau pendamping pasien anak DBD yang bersedia menjadi responden, dan manifestasi perdarahan dikonfirmasi melalui data rekam medis. Uji hipotesis dilakukan menggunakan uji Chi-square atau uji alternatif Fisher exact.Hasil : Didapatkan 32 pasien anak DBD di RSUP Dr.Kariadi selama periode penelitian. Berdasarkan hasil analisis data didapatkan terdapat hubungan yang bermakna antara jenis antipiretika yang digunakan dengan manifestasi perdarahan pada anak yang menderita DBD (p= 0,04). Anak yang mendapatkan antipiretika jenis non parasetamol sebelum dirawat di rumah sakit memiliki risiko 2,3 kali lebih besar untuk mengalami perdarahan dibandingkan dengan anak yangmendapatkan parasetamol.Simpulan : Didapatkan hubungan yang bermakna antara jenis antipiretika yang digunakan dengan manifestasi perdarahan pada anak DBD.Kata kunci : DBD, manifestasi perdarahan, jenis antipiretika
PERBEDAAN TINGKAT PENGETAHUAN IBU DAN TINDAKAN PENCEGAHAN DEMAM BERDARAH DENGUE DI WILAYAH ENDEMIS DAN NON ENDEMIS Rahadian, Dimas Aditya; Arkhaesi, Nahwa; Hardian, Hardian
MEDIA MEDIKA MUDA 2012:MMM VOLUME 1 NUMBER 1 YEAR 2012
Publisher : MEDIA MEDIKA MUDA

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Background: Dengue hemorrhagic fever is still an issue in Indonesia. DHF incidence rate in children shows a significant increase both in number of patients and epidemic area. Problems that still exist nowadays are people ignorance and inconsistent prevention effort. People in endemic and non-endemic area may have different knowledge and precaution towards DHF due to the environment and ease in gaining information about DHF.Aim: To prove the difference of knowledge and precaution towards DHF in mothers between endemic and non-endemic area.Method: This was an analytic-observational study with cross sectional design, which held from March- June 2012. The samples were mothers who had children less than 14 years old in age and lived in Gajahmungkur (endemic) and Sekayu (non-endemic). Sampling done by using questionnaire. Data were being tested statistically with X2.Result: There was no significant differences between age of the respondents, occupations, income, age of the children and DHF history in a family in both groups, while the education level showed significant difference (p<0,001). 46.2% of the respondents in endemic area had good knowledge level, while other respondents in non-endemic area had poor knowledge level (92.3%). Six respondents in endemic area had good precaution towards DHF (23,1%), but all of the respondents in non endemic area (100%) had poor precaution towards DHF. A chi-square test showed that there were significant different level of knowledge (p=0,002) and precaution towards DHF (p=0,01) in both groups.Conclusion: Knowledge level and precaution towards DHF of respondents in endemic area is higher than the respondents in non endemic area.Keywords: Endemicity, knowledge, precaution, DHF.
HUBUNGAN ANTARA TINGKAT PENGETAHUAN IBU TENTANG DEMAM TIFOID TERHADAP KEBIASAAN JAJAN ANAK SEKOLAH DASAR Putra, Ade; Arkhaesi, Nahwa; Hardian, Hardian
MEDIA MEDIKA MUDA 2012:MMM VOLUME 1 NUMBER 1 YEAR 2012
Publisher : MEDIA MEDIKA MUDA

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Abstract

Background Infectious disease abdominal typhus or typhoid fever is transmitted through food and drink that contaminated with S.typhi. In Indonesia, typhoid is endemic are often found in big cities. Typhoid fever is more commonly is closely associated with the snacking behavior.Aim to prove the association between the level of maternal knowledge about typhoid fever with snacking behavior of elementary school pupils.Methods This was an analytic-observational study with cross sectional study design. Samples of this study were mothers who had elementary school pupils children lived in Kedungmundu (endemic area). Sampling done by using questionnaire. Data were being tested statistically with Chi-square/ Fischer test.Result this study showed 13 mothers (72,2%) with moderate-high knowledge level about typhoid fever having elementary school pupil with rare snacking behavior and 5 mother (27,8%) having elementary school pupil with often snacking behavior. This study also showed 1 mother (16,7%) with poor knowledge level about typhoid fever having elementary school pupil with rare snacking behavior and 5 mothers (83,3%) having elementary school pupil with often snacking behavior. There was a significant association between mother’s knowledge level about typhoid fever and elementary school pupil snacking behavior(p=0,017, PR=3,0). there was no significant association between elementary school pupil snacking behavior and friends invitation (p=0,4), amount of pocket money(p=0,2), and the number of snack places.Conclusion Levels of maternal knowledge about typhoid fever had a significant association with snacking behavior of elementary school pupils.Keyword : Knowledge, typhoid fever, snacking behavior of elementary school pupils
PENGARUH PEMBERIAN ASAM LEMAK TRANS TERHADAP JUMLAH SEL DARAH PUTIH TIKUS SPRAGUE DAWLEY Pratama, Jefri; Tjahjono, Kusmiyati; Hardian, Hardian
MEDIA MEDIKA MUDA 2012:MMM VOLUME 1 NUMBER 1 YEAR 2012
Publisher : MEDIA MEDIKA MUDA

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Abstract

Latar Belakang : Suatu kondisi dimana sumsum tulang memproduksi sedikit sel darah putih disebut dengan leukopenia. Penyebab di Indonesia kemungkinan disebabkan oleh adanya tren perubahan gaya hidup, terutama pola makan barat yang mengandung tinggi kalori dan lemak bahkan juga tinggi asam lemak trans. Selain itu masyarakat juga banyak mengkonsumsi makanan goreng-gorengan (deep frying) yang mengandung tinggi asam lemak trans.Tujuan : Membuktikan pengaruh pemberian asam lemak trans terhadap jumlah sel darah putih tikus Sprague Dawley.Metode : Penelitian ini merupakan penelitian eksperimental murni dengan desain Randomized Control Group Pretest and Posttest Design. Subjek penelitian adalah 21 ekor tikus Sprague Dawley jantan berumur 8 minggu. Sampel dibagi menjadi 3 kelompok, yaitu kelompok kontrol yang diberi pakan standar, kelompok perlakuan 1 yang diberi pakan dengan asam lemak trans 5%, dan kelompok perlakuan 2 yang diberi pakan dengan asam lemak trans 10% selama 8 minggu. Masing-masing kelompok diambil darahnya sebelum dan sesudah perlakuan untuk diukur jumlah sel darah putihnya. Uji statistik yang digunakan adalah uji paired t-test, uji Wilcoxon dan uji independent t-test.Hasil : Didapatkan perbedaan selisih jumlah sel darah putih pada kelompok perlakuan 1 yang lebih rendah secara tidak bermakna (p=0,6) dibandingkan kelompok kontrol. Hal yang sama pada kelompok perlakuan 2 (p=0,5). Perbedaan selisih jumlah sel darah putih pada kelompok perlakuan 2 juga lebih rendah secara tidak bermakna (p=0,3) dibandingkan dengan kelompok perlakuan 1.Kesimpulan : Terjadi penurunan selisih jumlah sel darah putih yang tidak bermakna pada tikus Sprague Dawley setelah mendapatkan pemberian asam lemak trans.Kata Kunci : asam lemak trans, sel darah putih, leukopenia, tikus Sprague Dawley.
PENGARUH PENYULUHAN KESEHATAN TERHADAP TINGKAT PENGETAHUAN, SIKAP DAN PRAKTIK IBU DALAM PENCEGAHAN DEMAM BERDARAH DENGUE PADA ANAK Kusumawardani, Erika; Arkhaesi, Nahwa; Hardian, Hardian
MEDIA MEDIKA MUDA 2012:MMM VOLUME 1 NUMBER 1 YEAR 2012
Publisher : MEDIA MEDIKA MUDA

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Abstract

Latar Belakang: Penyuluhan kesehatan tentang DBD merupakan salah satu cara yang digunakan untuk menambah pengetahuan seseorang tentang DBD dengan tujuan mengubah atau mempengaruhi perilaku manusia dalam pencegahan DBD. Tujuan penyuluhan kesehatan tentang DBD adalah menginformasikan kepada masyarakat tentang penyakit tersebut.Tujuan: Penelitian ini bertujuan untuk mengetahui pengaruh penyuluhan kesehatan terhadap tingkat pengetahuan, sikap dan praktik ibu dalam pencegahan DBD pada anak.Metode: Penelitian ini adalah penelitian intervensional dengan rancangan quasi experimental non equivalent control group design pada periode Maret s/d Juni 2012. Penelitian dilakukan di wilayah Kelurahan Gajahmungkur (kelompok perlakuan) dan Kelurahan Tembalang (kelompok kontrol). Pada kelompok perlakuan diberikan penyuluhan kesehatan tentang DBD. Kelompok kontrol tidak mendapat penyuluhan apapun. Instrumen penyuluhan adalah penyuluhan langsung dan leaflet. Uji hipotesis yang dilakukan menggunakan Mann-Whitney dan Friedman.Hasil: Skor KAP kelompok perlakuan pada pretest adalah 106,07 (kategori buruk), posttest hari ke-15 adalah 131,59 (kategori sedang) dan posttest hari ke-30 adalah 135,07 (kategori sedang). Sedangkan pada kelompok kontrol pada pretest adalah 113,63 (kategori sedang), posttest hari ke-15 adalah 114,04 (kategori sedang) dan posttest hari ke-30 adalah 113,78 (kategori sedang). Pada kelompok perlakuan dijumpai peningkatan yang bermakna pada skor KAP sampai dengan hari ke-30 pengamatan (p<0,001), sedangkan pada kelompok kontrol perbedaan skor KAP tidak bermakna (p=0,9).Simpulan: penyuluhan kesehatan berpengaruh terhadap tingkat pengetahuan, sikap dan praktik ibu dalam pencegahan DBD pada anak.
HUBUNGAN TINGKAT PENGETAHUAN IBU MENGENAI PENYAKIT DBD TERHADAP KEJADIAN PENYAKIT DBD PADA ANAK SIDIEK, ABOESINA; Arkhaesi, Nahwa; Hardian, Hardian
MEDIA MEDIKA MUDA 2012:MMM VOLUME 1 NUMBER 1 YEAR 2012
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Abstract

Background: Dengue hemorrhagic fever (DHF) was still becomes a health issue in Indonesia. DHF incidence rate in children showed a significant increase both in number of patients and epidemic area. Problems that still exist nowadays were shortage of people’s knowledge towards DHF that leaves unawareness to prevention effort. Adequate knowledge was suspected to be a factor that could decrease the risk of being transmitted with DHF.Aim: To prove the relationship of mother’s level of knowledge of DHF towards DHF incidents at child.Method: This was an analytic-observational study with case control design. Research subjects of this study in case group were mothers who had child whom aged less than 14 years old and experiencing DHF. Research Subjects of control group were mothers who had child whom aged less than 14 years old and had not experiencing DHF and lived in Sekayu, Semarang. The data had been retrieved from samples by interviewing subjects using questionnaire. Data were being tested statistically with 2 test and Fisher exact test.Result: There were no significant differences between ages, occupations, level of education on respondent of both groups. The amount of poor leveled knowledge of case group’s respondent were 3 (8,8%) people, while the control group had 7 (8,8%) people. The amount of fair-good leveled knowledge of case group’s respondent were 31(91,2%), while the control group had 27(79,4%) people. There was not significant relationship between levels of knowledge towards DHF incidents at child (p=0,2).Conclusion: There was not significant relationship between levels of knowledge towards DHF incidents at child.Keywords: Knowledge, DHF.
HUBUNGAN ANTARA TINGKAT PENGETAHUAN IBU TENTANG DEMAM DENGAN PENGELOLAN DEMAM PADA ANAK Riandita, Amariila; Arkhaesi, Nahwa; Hardian, Hardian
MEDIA MEDIKA MUDA 2012:MMM VOLUME 1 NUMBER 1 YEAR 2012
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Abstract

Background: Fever is a common condition that occurs primarily in children. Treatment of fever in children is highly dependent on the role of parents, especially mothers. Different knowledge of mothers will result in the different wayof mothers to manage the fever in children.Objective: To find out the relationship between the level of maternal knowledge about the fever with the management of fever in their children.Methods: Analytical observational research with cross sectional approach. Subjects were mothers of children whom suffered ill that accompanied with fever whose underwent outpatient or had been treated in the ward infections department of Dr. Kariadi hospital. Data was collected from March-June 2012 using a structured questionnaire that has been tested. Data was analyzed with Chi Square test using SPSS ver 17 for Window.Results: The total of respondents in this study were 44 mothers. Most of the respondents were less educated and have family income above minimum wage. There were 52% of respondents who have low knowledge about the fever. Theresult shows that 50% of the total respondents have a good management of fever in tehir children. Based on the results using Chi square test, there was a significant association between mothers level of knowledge about the fever withthe management of fever in children.Conclusion: Mothers with high level knowledge about fever in children have a better management of fever in their children.Keywords: maternal knowledge, fever management, children.
PERBANDINGAN KUALITAS HIDUP PASIEN EPILEPSI LOBUS TEMPORAL YANG BEBAS KEJANG DENGAN YANG TIDAK BEBAS KEJANG PASCA AMIGDALOHIPPOKAMPEKTOMI Ashari, Ashari; Arifin, Muhamad Thohar; Hardian, Hardian
MEDIA MEDIKA MUDA 2012:MMM VOLUME 1 NUMBER 1 YEAR 2012
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Background : Epilepsy surgery is a choice of treatment for epilepsy patients who are resistant to anti-epileptic drugs. Epilepsy surgery is successful if the patient’s quality of life improved or better than before surgery and it can reduce seizure frequency.Aim : Prove the existences of quality of life differences in seizure-free patients compared with not seizure-free temporal lobe epilepsy patients post-amygdalohippocampectomy.Methodes : This is an Observational study with Cross Sectional design. The quality of life were assessed with QOLIE-31 questionnaire, while the patient’s seizure-free condition were taken from medical records. Then quality of life of seizure-free temporal lobe epilepsy patients were compared with not seizure-free patients after amygdalohippocampectomy. The statistical tests used were unpaired t-test if the data was distributed normally, and Mann-Whitney test if the data was not distributed normally.Results : 31 patients, 21 were seizure free (Engel 1) and 10 were not seizure free (Engel 2, 3 and 4), who have met the inclusion and exclusion criteria were analyzed. Statistical test results obtained with the seizure worry p = 0.003, overall QOL p = 0.001, emotional well-being p <0.001, energy / fatigue p <0.001, cognitive p = 0.002, medication Effects p = 0.01 , Social function p <0.001 . So that there were significant differences in quality of life of seizure-free temporal lobe epilepsy patients compared with not seizure-free patients.Conclusion : The quality of life of seizure-free temporal lobe epilepsy patients were significantly higher than those who were not seizure free after amygdalohippocampectomy.Key Words : Quality of life, QOLIE-31, Seizure-free, temporal lobe epilepsy, amygdalohippocampectomy
PENGARUH PEMBERIAN ASAM LEMAK TRANS TERHADAP JUMLAH SEL DARAH MERAH TIKUS SPRAGUE DAWLEY Hardanto, Gery Rifano; Tjahjono, Kusmiyati; Hardian, Hardian
MEDIA MEDIKA MUDA 2012:MMM VOLUME 1 NUMBER 1 YEAR 2012
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Latar Belakang : Anemia merupakan suatu gejala akibat menurunnya jumlah sel darah merah yang dapat disebabkan oleh konsumsi makanan cepat saji yang mengandung asam lemak trans. Asupan asam lemak trans memicu terjadinya respon inflamasi sistemik sehingga dapat menurunkan jumlah sel darah merah.Tujuan : Membuktikan pengaruh pemberian asam lemak trans terhadap jumlah sel darah merah tikus Sprague Dawley.Metode : Penelitian ini merupakan penelitian eksperimental murni dengan desain Randomized Control Group Pretest and Posttest Design. Subjek penelitian adalah 21 ekor tikus Sprague Dawley jantan usia 8 minggu. Sampel dibagi menjadi 3 kelompok, yaitu kelompok kontrol diberi pakan standar, kelompok perlakuan 1 diberi pakan dengan kadar asam lemak trans 5%, dan kelompok perlakuan 2 diberi pakan dengan kadar asam lemak trans 10% selama 8 minggu. Masing-masing kelompok diambil darahnya sebelum dan sesudah intervensi untuk diukur jumlah sel darah merahnya. Uji statistik yang digunakan adalah uji t-berpasangan dan uji t-tidak berpasangan.Hasil : Didapatkan perbedaan selisih jumlah sel darah merah pada kelompok yang diberi asam lemak trans 5% dan 10% yang lebih rendah secara tidak bermakna (p>0,05) dibandingkan kelompok kontrol. Perbedaan selisih jumlah sel darah merah kelompok yang diberi asam lemak trans 10% juga lebih rendah secara tidak bermakna (p>0,05) dibandingkan kelompok yang diberi asam lemak trans 5%.Kesimpulan : Terjadi penurunan selisih jumlah sel darah merah yang tidak bermakna pada tikus Sprague Dawley setelah mendapatkan pemberian asam lemak trans.Kata Kunci : Asam lemak trans, sel darah merah, anemia, tikus Sprague Dawley.
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN TERJADINYA VARISES VENA TUNGKAI BAWAH PADA WANITA USIA PRODUKTIF Adriana, Carina; Budiastuti, Asih; Hardian, Hardian
MEDIA MEDIKA MUDA 2012:MMM VOLUME 1 NUMBER 1 YEAR 2012
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Background : Varicose veins (VV) of lower extremity is superficial leg veins which are dilated and winding with abnormal valve function. Lower extremity VV may cause cosmetic problems that interfere with the appearance and decreased work productivity.Aim : The study aims to investigate the factors associated with the occurrence of lower extremity VV in women of productive age.Method : The study is an analytic observational using case control study design. The samples were taken with consecutive sampling. Subjects were women of productive age, comprising of 30 women with lower extremity VV (case) and 30 women without lower extremity VV (control). The data collected is characteristic of subjects and related factors to lower extremity VV. Data analysis were performed using SPSS Windows Ver 17.0.Results : The incidence of lower extremity VV in subjects with a family history was higher than in subjects with no family history (OR = 50,1; 95% CI=6,0 to 420,4). The occurrence of lower extremity VV was higher in subjects with a Body Mass Index (BMI)> 23 than subjects with BMI ≤ 23 (OR=8,5; 95% CI= 2,4 to 30,5). The incidence of lower extremity VV in the subject with a history of prolonged standing was higher than subjects with no history of prolonged standing (OR=36,0; 95% CI = 8,1 to 159,9). While the variables of age (OR = 1,6), multiparity pregnancy (OR = 4,3), and hormonal contraception (OR = 1,9) could not yet be concluded as a risk factor.Conclusion : Factors associated with the occurrence of lower extremities VV were a family history, overweight/obesity, and prolonged standingKeywords : Lower extremity varicose veins, family history, overweight/obesity, prolonged standing.
Co-Authors A. Fatmawati Rachman ABOESINA SIDIEK Ade Erma Listiawati Ade Putra Adisty Octaviyani, Adisty Alifianto Parham Parakkasi, Alifianto Parham Amariila Riandita Ameltia Veraldy Ariosta Ariosta, Ariosta Ashari Ashari Asih Budiastuti Auliya Husen, Auliya Carina Adriana Ch. Suharti Ch. Suharti, Ch. Suharti Chatarina Suharti, Chatarina Daisy Syakhsiatusy Syahiqoh Darmawati Ayu Indraswari Dimas Aditya Rahadian Dwitania Azhari, Dwitania Edwin Basyar Elfian Rachmawati Endang Ambarwati, Endang Erika Kusumawardani Fadilah Kusuma Dewi, Fadilah Kusuma Fajar Herbowo Niantiarno Faramita Nur Izzaty, Faramita Nur Febrina Triadita, Febrina Gabriella Carolina Hutapea, Gabriella Carolina Gery Rifano Hardanto Hardiansyah Hardiansyah Harsoyo Notoatmodjo Hayes, Clarin Helmia Farida Herawati Herawati Hexanto Muhartomo, Hexanto Ilva Widyaningtyas Savitri, Ilva Widyaningtyas Jefri Pratama Khaliza Cita Kresnanda Khoirunnisa, Denisa Kusmiyati Tjahjono Laode Rijai Lathifa Putry Fauzia, Lathifa Putry Maureen Tania Widyasaputra MM Hapsari, MM Muhamad Thohar Arifin Muhammad Nadhim RP, Muhammad Muhammad Thohar Arifin Munirah Munirah Nabila Amalina Nahwa Arkhaesi Putri, Adinda Wafdani Ratih Vierda Octaviani, Ratih Vierda Rina Prihatingrum, Rina Santikatmaka, Alfian Sekar Arum Nuring Kurnia, Sekar Arum Nuring Septiany, Maria Carolina Sulistiarini, Riski SUTRIONO SUTRIONO Tanjung Ayu Sumekar Tanra, Andi Alfia Muthmainnah Yosef Purwoko Yusdiyanti, Ditha