Herry Garna
Department of Child Health, Faculty of Medicine, Padjadjaran University, Bandung

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Journal : Paediatrica Indonesiana

The Etiology of Nosocomial Infections in Pediatric Patients at the Department of Child Health, School of Medicine Padjadjaran University Hasan Sadikin General Hospital, Bandung Garna, Herry
Paediatrica Indonesiana Vol 33 No 5-6 (1993): May 1993
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi33.5-6.1993.100-7

Abstract

Tbe distribution of pathogens causing nosocomial gastroenteritis was E. coli (69.2%), Salmonella sp (23.1%), rotavirns (6.4%) and Shigella sp (1.3%) . Klebsiella pneumoniae seemed to be the pathogen most frequently associated with nosocomial skin infections (26. 7%), followed by Enterobacter aerogenes (20.0%), E. coli, Ps. Aeruginosa and S. aureus, each in 13.3% and others 03.4%). Salmonella sp was the pathogen most frequently associated with nosocomial bacteremia (20.2%), followed by Klebsiella sp 07.9%), S. a/bus 04.3%), Enterobacter sp 01.9%), Pseudomonas sp (9.5%), S. aureus (9.5%) and others (16. 7%). In nosocomial urinary tract infections, the result was E. coli (32.9%), Klebsiella pneumoniae (20.5%), Enterobacter sp 03. 7%), Citrobacter diversus (6.8%) and others (26.1%). In general, E. coli was the most frequently reported pathogens ( 42.0%), followed by Salmonella sp 07.1%), Klebsiella sp (10.2%), Citrobacter sp (7.2%), S. a/bus (4.5%), Pseudomonas sp (4.2%), S. aureus (3.6%) and others 01.2%), respectively.
Results of Salmonella typhi culture in patients with suspected typhoid fever, treated in the Department of Child Health Medical School, Padjadjaran University, Hasan Sadikin General Hospital Bandung Sekarwana, Nanan; Garna, Herry; S., Azhali M.
Paediatrica Indonesiana Vol 29, No 5-6 (1989): May 1989
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi29.5-6.1989.105-11

Abstract

From October to December 1984, examination has been carried out on Salmonella typhi cultures from blood, bone marrow, faeces and urine of 43 patients suffering from suspected typhoid fever treated in the Department of Child Health, Medical Schooll Hasan Sadikin General Hospital, Bandung.It was apparent that among these 43 patients, 51.2% were males and 48.8% females. The greater number of them were more than 5 years old (64.4%). The results of Salmonella typhi cultures were obtained  from 65% of the patients, consisting of 65% positive cultures from bone-marrow and 40% positive cultures from blood that showed a statistically significant difference (p < 0.05).Likewise, the time for matter-sampling for the examinations was based on the culture results, both on blood-culture and that of bone-marrow, statistically a significant was found (p < 0.05), whereas the results of cultures based on previous vaccination history and the administration of chloramphenicol prior to treatment did not differ significantly.It was obviously clear that the results of bone-marrow culture were more successful compared to those from blood culture, so that it should necessarily be emphasized, as to these examinations on culture from each patient with suspected typhoid fever, especially those patients hospitalized during the third week of their illness.
Tuberculosis prevalence among underfive children in household contact with negative acid fast bacilli adult pulmonary tuberculosis Iskandar, Harry; Nataprawira, Heda Melinda D.; Garna, Herry; Djais, Julistio T.B.
Paediatrica Indonesiana Vol 48 No 1 (2008): January 2008
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi48.1.2008.18-22

Abstract

Background Risk of tuberculosis (TB) transmission is greatest if achild has household contact with positive acid fast bacilli (AFB)adult pulmonary TB. Risk of TB transmission from negative AFBadult pulmonary TB to underfive children is unknown.Objective To find out the prevalence of TB infection and diseaseamong underfive children in household contacts with negativeAFB adult pulmonary TB.Methods The study was performed at Balai Kesehatan ParuMasyarakat (BKPM) Bandung on underfive children who live inthe same house with negative AFB adult pulmonary TB fromFebruary to July 2006. History taking, physical examination,anthropometric measurement, chest radiographs, and tuberculinskin test were performed to all study subjects. Subjects were thencategorized as TB infection(positive tuberculin test only) or disease(defined based on Pulmonology Workgroup of IndonesianPaediatrics Council criteria, 2005).Results Sixty one children (32 males and 29 females) had contactwith 54 negative AFB adults pulmonary TB. Tuberculosis infectionwas found in six (10%), while disease was found in 10 (16%)children. The prevalence of TB infection was 10% (95% CI2.3;17.3) while prevalence of TB disease was 16% (95% CI7.1;24.7).Conclusion Tuberculosis infection and disease prevalence isconsiderably high in household contact with negative EFB adultpulmonary TB.
Catheter Related Infections in Pediatric Patients Garna, Herry
Paediatrica Indonesiana Vol 33 No 5-6 (1993): May 1993
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi33.5-6.1993.108-14

Abstract

During a 9-month prospective study, from August, 1988 to April, 1989, a total number of 4328 hospitalized pediatric patients at the Department of Child Health, Padjadjaran University, Hasan Sadikin General Hospital Bandung, were observed to identify skin and soft tissue nosocomial infections (not included postoperative), especially catheter related injections. The gastroentestinal tract was the most frequent site of nosocomial infections (44.3%), then subsequently followed by skin infection (22.6%), bacteremia (16.3%) and urinary tract infection (14.1%). The most frequent cause of nosocomial skin infections like phlebitis was IVFD occurring in 82 out of 93 patients (88.2%). The overall phlebitis attact rate was 4.2% . When the duration of infusion is devided into 3 groups of 0-36 hours, 37-72 hours and ≥ 73 hours, then it becomes clear that the longer the duration of infusion, the higher the attack rate (x2=8.07, p&lt;0.05). Klebsiella pneumonia seemed to be the pathogen most frequently associated with nosocomial skin infections (26. 7%), followed by Enterobacter aerogenes (20.0%), and then E. coli, Ps. aeruginosa and S. aureus 13.3% each. It could be concluded that the risk of contracting phlebitis from JVFD with a duration &nbsp;of ≥ 73 hours was. 1.9 times higher than that of less than 72 hours.
Correlation between serum albumin and creatinine levels in children with nephrotic syndrome Sapartini, Gartika; Rachmadi, Dedi; Garna, Herry
Paediatrica Indonesiana Vol 48 No 6 (2008): November 2008
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (118.09 KB) | DOI: 10.14238/pi48.6.2008.354-7

Abstract

Background Nephrotic syndrome is a glomerular disordercharacterized by massive proteinuria, hypoalbuminemia, edema,and hyperlipidemia. Hypoalbuminemia in nephrotic syndromeleads to hypovolemia, a decrease in renal perfusion and glomerularfiltration rate. Serum creatinine level reflects the glomerularfiltration rate.Objective The aim of this study was to determine the correlationbetween serum albumin and creatinine levels in children withnephrotic syndrome.Methods A cross-sectional study was carried out on children withidiopathic nephrotic syndrome, aged between 1 to 14 years old,admitted to Pediatric Department in Hasan Sadikin Hospitalfrom January 2001 to September 2007. We used data frompatients' medical records to obtain serum albumin and creatininelevels during nephrotic stage. Statistical analysis using Pearsoncorrelation test was performed to establish the correlation betweenserum albumin and creatinine levels. The type of correlation wasdetermined by regression analysis.Results Subjects were 113 children, consisted of 81 boys (72%)with mean of age 6.8 (SD 3.3) years. Mean of serum albumin andcreatinine levels were 1.4 (SD 0.4) g/dL and 0.7 (SD 0.4) mg/dL, respectively. Analysis using Pearson correlation test showeda moderate (r=-0.478) significant correlation (P&lt;O.Ol) betweenserum albumin and creatinine levels in children with nephroticsyndrome. Regression analysis suggested a negative linearrelationship between serum albumin level as the independentvariable (X) and serum creatinine level as the dependent variable(Y) by using equation Y = 1.328-0.460X.Conclusion In patients with nephrotic syndrome there is amoderate negative correlation between serum albumin andcreatinine levels.
Clinical risk factors for dengue shock syndrome in children Junia, Jujun; Garna, Herry; Setiabudi, Djatnika
Paediatrica Indonesiana Vol 47 No 1 (2007): January 2007
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi47.1.2007.7-11

Abstract

Background Dengue shock syndrome (DSS) is a seriouscomplication of dengue hemorrhagic fever (DHF) which maycause death in more than 50% cases if not treated properly andpromptly. Clinical, viral, and epidemiological risk factorsdetermine the occurrence of DSS. Identifying risk factors for thedevelopment of shock in patients with DHF can increase theawareness of clinicians to perform a close monitoring.Objective To determine the clinical risk factors for DSS.Methods This case control study was conducted on DHF andDSS patients admitted to the Department of Child Health,Medical School, University of Padjadjaran, Dr. Hasan SadikinHospital Bandung from January 2004 to December 2005. Thesubjects were patients aged less than 14 years who fulfilled WHOcriteria (1997). The exclusion criteria were history of asthma,diabetes mellitus, sickle cell anemia, typhoid, sepsis, and measles.The risk factors for DSS were analyzed using chi-square test,calculation of odds ratio, and logistic regression analysis.Results Of 1,404 patients with suspected DHF, 600 met the studycriteria; 200 patients of DSS and 400 patients of DHF as controlgroup were identified. Univariate analysis showed that there wasassociation between DSS and age 5-9 years (OR=1.67, 95%CI1.08;2.58), overweight (OR=1.88, 95%CI 1.22;2.90), vomiting(OR=1.44, 95%CI 1.02;2.04), abdominal pain (OR=2.07,95%CI 1.46;2.92), and severe bleeding (OR=13.6, 95%CI5.96;31.03). By logistic regression analysis, it was found that age5-9 years (OR=1.62, 95%CI=1.03–2.53), overweight (OR=1.97,95%CI=1.29–3.08), and persistent abdominal pain (OR=2.08,95%CI =1.44–2.99) were independent risk factors for DSS.Conclusion Age 5-9 years, overweight, and persistent abdominalpain are the risk factors for DSS.
Relationship between atopic manifestations, family history of atopic disease and cord blood IgE levels in children Hafsah, Tisnasari; Soepriadi, Myrna; Setiabudiawan, Budi; Garna, Herry
Paediatrica Indonesiana Vol 47 No 6 (2007): November 2007
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi47.6.2007.278-82

Abstract

Background The incidence of atopic disease tends to increaseover the past few decades and its morbidity interferes with thequality of life and health. Prediction of the disease is importantfor early prevention.Objective To evaluate the relationship between atopicmanifestations, family history (FH) of atopic disease and cordblood IgE (CB-IgE) levels.Methods We conducted an analytic observational study withcohort retrospective design on children with an average age of 3years whose CB-IgE had been measured at delivery inKiaracondong Primary Health Care during October–December2004. Manifestations of atopic disease were recorded using ISAACquestionaire for allergy. Chi-square, Mann-Whitney test, andlogistic regression analysis were used for analysis.Results Cord blood IgE was measured on 124 children after birth.Only 94 children (76%) fulfilled the inclusion criteria. Atopicdisease was found in 17 children (18%), consisting of 8 childrenwith atopic dermatitis, 4 with allergic rhinitis, and 5 suffered fromboth. There were significant differences in the mean value of CB-IgE (Z M-W =4.60; P&lt;0.001) and FH (x 2 =19.059; P&lt;0.001)between atopic and non atopic children. Cut off point of the CB-IgE concentration was 1.4 IU/mL (77.7%). The highest probabilityfor atopic manifestations was found in children who had highCB-IgE and positive FH (P=45%). Relative risk of children withhigh CB-IgE level in positive FH group was 3.636 (95% CI0.943;14.016).Conclusion CB-IgE level and family history of atopic disease arerisk factors for the development of atopic manifestation.
Effect of exclusive breast-feeding on the linear growth of children aged 24-36 months in Bandung's urban slum area Ismawaty, Nenden; Djais, Julistio; Garna, Herry
Paediatrica Indonesiana Vol 48 No 2 (2008): March 2008
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi48.2.2008.120-4

Abstract

Background Breast milk is an ideal nutrition source for infantsbecause of its balanced composition, naturally adjusted toinfants' need for growth and without any expenses. However,low education mothers living in slum areas are ignorant towardsinformations about the importance of exclusive breast-feeding.Objective To observe the effects of exclusive breast-feeding onlinear growth of children aged 24-36 months in urban slumsarea.Methods A cross-sectional study was carried out on 343children consisted of 188 exclusively breastfed infants and 155nonexclusively breastfed infants in Puskesmas Cigondewaharea on August to September 2007. Anthropometricmeasurements were performed to obtain linear growth status.Data were analyzed by using odd ratio (OR). The first step wasperformed univariately to assess the effect of data variables.Henceforth, factors which significantly influence the growthwill be assesed by multivariate calculation.Results Normal linear growth status was found in 109 (66.1%)exclusively breastfed compared with 56 (33.9%) nonexclusivelybreastfed children. Univariate analyzes showed that factorsthat influenced children normal linear growth were exclusivebreast-feeding (OR: 2.44; 95%CI: 1.58;3.78), industrial productporridge as complementary food (OR: 1.65; 95%CI: 1.00;2.72),and frequency of illnesses &lt;6x/year (OR: 1.57; 95%CI: 1.02;2.42).The result of multinomial logistic regression analyzes showed thatexclusive breast-feeding became the only factor that influencechildren linear growth (OR: 2.254; 95%CI: 1.438;3.533).Conclusion Exclusive breast-feeding has significant positive effect onlinear growth of children.
Giardiasis in daycare centers at Rancabali tea plantation, Bandung District, Indonesia Widajanti, Endang; Garna, Herry; Chairulfatah, Alex; Hudaya, Dadang
Paediatrica Indonesiana Vol 43 No 5 (2003): September 2003
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (299.836 KB) | DOI: 10.14238/pi43.5.2003.158-61

Abstract

Background In developing countries, the prevalence of giardia-sis in daycare centers is considerably high. There had been inad-equate report of giardiasis in Indonesia.Objective To know the prevalence of giardiasis in children andthe number of children with symptomatic and asymptomatic giar-diasis who attended daycare centers at Rancabali tea plantation,Bandung district.Methods This descriptive study was conducted in daycare cen-ters between August to October 2002. Giardiasis was defined asthe occurrence of G. lamblia cyst in stool specimen independentfrom the presence or absence of symptoms. Four of 12 daycarecenters were chosen by cluster random sampling. All children aged1 to 60 months attending daycare and staying for at least 2 weekswere included in this study. Three consecutive stool specimen pre-served by 10% formalin, concentrated by formalin ether, were ex-amined microscopically to find the G. lamblia cyst.Results Giardia lamblia cysts were found in 27 (29%) of the 92children attending the daycare centers at Rancabali tea plantation(95%CI 20;38.6%). Of these children, 15 showed symptoms suchas diarrhea episodes (8 children), diarrhea (5 children), bloating (5children), abdominal cramp (5 children), and vomiting (3 children).Three children showed mild to moderate malnutrition. Ten childrenaged 13 to 36 month-old with G. lamblia-positive stool showed suchsymptoms.Conclusion The prevalence of G. lamblia infection in children at-tending daycare centers at Rancabali tea plantation was almostsimilar with other place in developing countries. More than half ofpatients had symptomatic disease
Antimicrobial Resistance of Nosocomial Infections in Children Garna, Herry
Paediatrica Indonesiana Vol 33 No 7-8 (1993): July 1993
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi33.7-8.1993.133-41

Abstract

A 9 month prospective study , from August 1988 to April 1989, was performed at the Department of Child Health, Medical School, Padjadjaran University, Hasan Sadikin Hospital Bandung. The aim of the study was to identify the pattern of sensitivity of bacteria causing nosocomial infections. It was revealed that among 4328 hospitalized pediatric patients, a total number of 342 patients had one or more nosocomial infections, yielding 411 episodes. Twenty-five per cent of isolated S. aureus was resistant to either ampicillin or oxacyllin. Higher percentages of resistance were observed in S. albus, i.e., to penicillin (53.3%) and oxacyllin (46.7%), and to cefuroxime, erythromycin and clindamycin (each in 40.0% of isolate). E. coli was In 86.3% resistant-to ampicillin, 78.4% to chloramphenicol (and thiamphenicol), 56.8% to tobramycin and 48.2% to gentamicin. The isolated Salmonella sp was almost 100% resistant to ampicillin and chloramphenicol (and thiamphenicol) but was highly sensitive to amikacin, cefotaxime and netilmicin, arround 100%. Pseudomonas sp was 92.9% resistant to ampicillin, 85.7% to chloramphenicol (and thiamphenicol) and 78.6% to cefuroxime; on the contrary it was 92.9% sensitive to amikacin. It can be concluded that gram-negative microorganisms were in general showed highly resistant to ampicillin, chloramphenicol (and thiamphenicol), tobramycin, and gentamicin; on the other hand more than 90% were sensitive to netilmicin, cefotaxime and amikacin.
Co-Authors Achmad Surjono, Achmad Adjat Sedjati Rasyad Agnes Rengga Indrati Agus Firmansyah Ahmad Suardi, Ahmad Alex Chairulfatah Ani Melani Maskoen Aniceto Cardoso Barreto, Aniceto Cardoso Ardini Saptaningsih Raksanagara, Ardini Saptaningsih Ari Indra Susanti, Ari Indra Arief Budiman Aulia Fitri Swity, Aulia Fitri Azhali M. S., Azhali M. Bachti Alisjahbana Budi Setiabudiawan Cissy B. Kartasasmita Dadang Hudaya S, Dadang Hudaya Dany Hilmanto Dedi Rachmadi Dessy Afrianti, Dessy Dida A. Gurnida Dida Akhmad Gurnida Dina Garniasih, Dina Djatnika Setiabudi Dwi Prasetyo Dzulfikar D. Lukmanul Hakim Eddy Fadlyana Endah Pujiastuti, Endah Fina Meilyana Firman F. Wirakusumah Firman Wirakusumah, Firman Fiva A Kadi, Fiva A Gartika Sapartini Harry Iskandar, Harry Heda Melinda D. Nataprawira Henne Giyantini, Henne Herman, Herry Hidayat Wijayanegara Hudaya, Dadang Husin, Farid Ida Parwati Irawan, Gaga Irvan Afriandi Ismawaty, Nenden Iwin Sumarman Iwin Suwarman Julistio Djais, Julistio Julistio T. B. Djais, Julistio T. B. Julistio T.B. Djais, Julistio T.B. Junia, Jujun Kamila, Nurul Auliya Kusnandi Rusmil Laili, Fauzia Linda Marlina, Linda Lony Novita, Lony M.S. Azhali Maryamah, Aam Meijerink, Hinta Mohamad Yanuar Anggara Nanan Sekarwana Novila Sjafri Bachtiar Novilia Sjafri Bachtiar Nur Melani Sari, Nur Melani Nurakilah, Heni Okinarum, Giyawati Yulilania Ponpon Idjradinata Ponpon S Idjradinata R.M Ryadi Fadil, R.M Ryadi Rahmat Budi Reinout van Crevel Rengga Indrati, Agnes Reni Ghrahani Retno Saraswati Sitomorang, Ingrid Rita Sjarif Hidajat, Sjarif Soenarjati Soedigo Adi Soepriadi, Myrna Sri Endah Rahayuningsih Sugih, Siti Sunjaya, Deni K. Susiarno, Hadi Susiarno, Hadi Sutisna, Ma'mun Tina Ramayanthi, Tina Tisnasari Hafsah, Tisnasari Titik Respati Tono Djuwantono van der Venn, Andre Widajanti, Endang Wiwin Winiar