Articles

Found 22 Documents
Search

ANALISIS PENGARUH WHOLE BODY VIBRATION (WBV) TERHADAP KELUHAN LOW BACK PAIN (LBP) PADA OPERATOR ALAT BERAT DI PT. X Kurniati, Halisa; Flora, Rostika; Sitorus, Rico Januar
JUMANTIK (Jurnal Ilmiah Penelitian Kesehatan) Vol 4, No 1 (2019): Mei 2019
Publisher : UIN Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Low back pain is a common disease affecting almost all individuals at some point in their life. Low back pain is multifactorial in origin. The cause of increased prevalence of low back pain in populations of professional drivers is often uncertain. The factor reported to be most strongly associated with low back pain are exposure to whole body vibration. Other possible risk factors with weaker or inconsistenst evidence for influencing low back pain are individual factors (age, time of work, body mass index and physical activitity). This research is conducted observasionally with cross sectional design with a large sample of 70 people which selected by purposive sampling. Data collected from accelerometer, questionnaires, observation and interviews. The results of research obtained that exposure whole body vibration suffered by operator is 0,543 m/s2 and complaints of low back pain on a heavy equipment operators at PT. X is 64,3 %. Bivariat analysis showed that there are significant relationship between whole body vibration (p<0,05;95 % CI 0,99-2,99 OR 1,723), age (p<0,05; 95 % CI 1,42-3,77 OR 2,31), time of work (p<0,05; 95 % CI 1,07-7,81 OR 2,89) with low back pain. There was no significant relationship between body mass index (p>0,05; 95 % CI 0,68-1,37 OR 0,969) and physical activity (p>0,05; 95 % CI 0,55-1,14 OR 0,798) to low back pain. This research conclude that there is correlation whole body vibration with complaints of low back pain. Keyword:  whole body vibration, low back pain, operator
Korelasi Antara Hypoxia Inducible Factor-1α Dengan Aktivitas Enzim Creatine Kinase Jaringan Otot Jantung Tikus Pada Aktivitas Fisik Aerobik dan Anaerobik Flora, Rostika
Biomedical Journal of Indonesia: Jurnal Biomedik Fakultas Kedokteran Universitas Sriwijaya Vol 1, No 1 (2015)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Aktivitas fisik aerobik dan anaerobik tanpa hari istirahat dapat mengakibatkan terjadinya hipoksia dan perubahan histopatologi pada otot jantung. Kondisi hipoksia berkorelasi terhadap perubahan histopatologi pada otot jantung. Untuk mengetahui apakah kondisi hipoksia ini juga berkorelasi dengan indikator kerusakan jaringan otot jantung, perlu dilakukan penelitian lebih lanjut. Penelitian ini bertujuan untuk mengetahui korelasi antara hipoksia yang terjadi pada otot jantung akibat pembebanan aktivitas fisik aerobik dan anerobik tanpa hari istirahat dengan aktivitas enzim CK jaringan otot jantung. Jaringan otot jantung berasal dari tikus yang diberi aktivitas fisik aerobik dan anaerobik menggunakan treadmill selama 1,3,7 dan 10 hari tanpa hari istirahat. Kemudian dilakukan pengukuran kadar HIF-1α sebagai parameter hipoksia dan aktivitas enzim CK sebagai parameter terjadinya kerusakan sel otot jantung. Hasil penelitian menunjukkan bahwa, terdapat korelasi yang sangat kuat  antara konsentrasi HIF-1α dengan aktivitas CK jaringan pada kelompok anaerobik (r=0,91, p<0,05), sedangkan pada kelompok aerobik terdapat korelasi yang sedang (r=0,48, p<0,05). Kondisi hipoksia pada otot jantung yang terjadi akibat aktivitas fisik aerobik dan anaerobik  yang dilakukan selama 10 hari tanpa hari istirahat berkorelasi sangat kuat dengan indikator kerusakan jaringan pada kelompok anaerobik dan berkorelasi sedang pada kelompok aerobik.
Correlation of hypoxia inducible factor-1α and vascular endothelium growth factor in rat myocardium during aerobic and anaerobic exercise Flora, Rostika; Freisleben, Hans-Joachim; Ferdinal, Frans; Wanandi, Septelia I.; Sadikin, Mohamad
Medical Journal of Indonesia Vol 21, No 3 (2012): August
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (837.72 KB) | DOI: 10.13181/mji.v21i3.493

Abstract

Background: Exercise increases the need for oxygen to generate ATP through oxidative phosphorylation. If the high energy demand during exercise is not balanced by sufficient oxygen supply, hypoxia occurs in skeletal muscle tissue leading to upregulation of hypoxia inducible factor-1α (HIF-1α). The activity of HIF-1α increases the expression of various genes in order to reduce the metabolic dependence on oxygen and to increase oxygen supply to the tissue, e.g., VEGF which plays a role in angiogenesis. In myocardium, it is unclear whether exercise leads to hypoxia and whether HIF-1α and VEGF play a role in the mechanism of hypoxic adaptation. This study aimed to investigate the correlation of HIF-1α and VEGF in heart muscle tissue of rats during aerobic and anaerobic exercise.Methods: A rat treadmill was used with a specific exercise program for 1, 3, 7 and 10 days. The concentrations of HIF-1α and VEGF were measured the myocardium.Results: Both, HIF-1α protein and VEGF were increased (p &lt; 0.05) in the groups with aerobic and anaerobic exercise. Concentrations of HIF-1α were highest on the first day of activity, being higher in the anaerobic than in the aerobic group (156.8 ± 33.1 vs. 116.03 ± 5.66). Likewise, the highest concentration of VEGF in the group with anaerobic exercise occurred on the first day (36.37 ± 2:35), while in the aerobic group, VEGF concentration was highest on day 3 (40.66 ± 1.73). The correlation between the myocardial tissue consentrations of HIF-1α and VEGF is moderate (r = 0.59) in the aerobic group and strong in the anaerobic group (r = 0.69).Conclusion: Aerobic and anaerobic exercise increase HIF-1α and VEGF concentrations in rat myocardium in specific patterns. The anaerobic condition triggers vascularization stronger and obviously earlier than aerobic exercise. (Med J Indones. 2012;21:133-40)Keywords: Exercise, HIF-1α, myocardium, VEGF
Hippocampal Brain Derived Neurothropic Factor Levels in Response to Anaerobic Physical Exercises Zulkarnain, Mohammad; Flora, Rostika; Juliastuti, Juliastuti; Apriany, Anita; Pujiana, Dewi; Andrianti, Septi
International Journal of Public Health Science (IJPHS) Vol 6, No 2: June 2017
Publisher : Institute of Advanced Engineering and Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/.v6i2.6643

Abstract

Anaerobic physical exercise does not only improve body fitness, but it also increases cognitive functions. The increase of cognitive functions is mediated by the increase of Brain Derived Neurothropic Factor (BDNF) level. Several studies revealed that anaerobic physical exercise can increase the BDNF level inhippocampal tissues. However, it is still questionable whether or notthe frequency of exercise influences the production of BDNF inhippocampal tissues. This study was to find out the BDNF mean level inhippocampal tissue of Wistarrats which were treated with anaerobic physical exercises conducted in different frequencies.This study used post test only control groupdesign. The research subject was 28 rats of Rattusnorvegicus strain wistar divided into 4 groups; 1 control group and 3 treatment groups (one-time, three-time, and five times a week treatment). The anaerobic physical exercise used animal treadmill running in the speed of 35m/min for 20 minutes at four-minute intervals. The mean levels of BDNF were increased in all treatment groups compared with control group (151.588 vs 57.059). The highest mean level of hippocampal tissue BDNF was found in the treatment group of three times a week (177.701). There was a significant difference in BDNF mean levels of Wistar rat brain tissues among the treatment groups.
VASCULAR ENDOTHELIAL GROWTH FACTOR AS AN INDICATOR OF ANGIOGENESIS IN BRAIN TISSUE OF WISTAR RAT TREATED WITH ANAEROBIC PHYSICAL EXERCISES Flora, Rostika; Zulkarnain, Muhammad; Ardi, Yuliana; Sorena, Esti; Wati, Roslina; Wena, Syokuma; Juliansyah, Rahmad Aswin; Slamet, : Samwilson
International Journal of Public Health Science (IJPHS) Vol 4, No 3: September 2015
Publisher : Institute of Advanced Engineering and Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v4i3.8692

Abstract

Anaerobic physical exercise is a high-intensity exercise that needs quick energy supplies obtained in a very short time but it can not be done in continuously. However, this exercise may result in tissue hypoxia which is characterized by the increase of HIF-1α concentration. The presence of HIF-1α will induce the secretion of VEGF and, eventually, trigger angiogenesis. Nevertheless, it is still unclear whether anaerobic physical exercise will also cause hypoxia in which this condition will increase the concentration of VEGF in brain tissues. The aim of this study was to find out the effect of anaerobic exercise frequency towards VEGF concentration of Wistar rat brain tissues. This was experimental study using post test only control group design. Brain tissues were taken from rats treated with anaerobic physical activities using treadmill. This exercise was given in different frequencies; one time, three times, and seven times a week. Then, VEGF concentration of brain tissues was examined as an indicator of angiogenesis. The data collected were analyzed using independent t-test. The results of this study showed that anaerobic physical exercise done once a week could significantly increase VEGF concentration (p < 0.05) if compared with the one in control group (95.21 ± 31.99 v.s. 63.36 ± 11.01 pg/mL). Meanwhile, VEGF concentration of treatment groups given exercise three times a week (47.97 ± 10.68 pg/mL) and seven times a week (40.56 ± 13.98 pg/mL) showed a significant decrease if compared with that of control group (63.36 ± 11.01 pg/mL). Anaerobic physical activities affected VEGF concentration as an indicator of angiogenesis in brain tissue of wistar rats. Keyword: Vascular Endhothelial Growth Factor, Angiogenesis, Anaerobic, Physical Activities, Brain Tissues
Myocardial damage after continuous aerobic and anaerobic exercise in rats Flora, Rostika; Ferdinal, Frans; Hernowo, Bethy S.; Wanandi, Septelia I.; Sadikin, Mohamad; Freisleben, Hans-Joachim
Medical Journal of Indonesia Vol 22, No 4 (2013): November
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (813.04 KB) | DOI: 10.13181/mji.v22i4.601

Abstract

Background: Regular physical activity is highly recommended in preventive, curative, and rehabilitative programs in order to promote health, especially cardiovascular health. However, physical activity can also cause sudden death. In athletes, sudden death may occur during sport competitions, with myocardial infarction as the most common etiology. It is suspected that continuous training without any rest-day play a role in cardiac muscle damage and sudden death during competition. Our study was aimed to learn about cardiac muscle adaptation on continuous aerobic and anaerobic physical activity without any rest-day. Methods: The specimens in our study were cardiac muscle tissue obtained from rats that had performed aerobic and anaerobic physical activity on treadmill for 1, 3, 7, and 10 days without any rest-day. Blood gas analysis and hematological assessment were used as parameters of systemic adaptation to hypoxia during physical activity. Moreover, histopathology of cardiac muscle tissue was performed as parameter for cardiac muscle damage.Results: The results showed that aerobic and anaerobic physical activity caused a systemic hypoxic condition and triggered adaptation responses. Cardiac muscle damage occurred on the 10th day in both treatment groups, with more severe damage observed in the group with anaerobic physical activity. The tissue protein level in the anaerobic group increased progressively on the 10th day.Conclusion: Physical activity may result in hypoxia and systemic adaptation. Aerobic and anaerobic physical activities performed for 10 days without any rest-day may cause cardiac muscle damage. (Med J Indones. 2013;22:209-14. doi: 10.13181/mji.v22i4.601)Keywords: Cardiac muscle, cardiac muscle damage, histopathology, physical activity
Tumor Necrosis Factor-α sebagai Prediktor Terjadinya Anemia pada Ibu Hamil di Wilayah Endemis Malaria Flora, Rostika; Mukni, Mukni; Girsang, Bina Melvia; Purwanto, Sigit
Jurnal Kesehatan Masyarakat Nasional Vol. 9 No. 3 Februari 2015
Publisher : Faculty of Public Health Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (220.274 KB) | DOI: 10.21109/kesmas.v9i3.695

Abstract

Ibu hamil yang berada di daerah endemis malaria sangat rentan terhadap infeksi malaria selama kehamilan. Gejala malaria pada kelompok ini sering asimptomatik atau bahkan tidak terdeteksi sama sekali karena adanya efek imunitas protektif melalui infeksi yang berulang. Adanya peningkatan kadar tumor necrosis factor-alpha (TNF-α) dapat dijadikan indikator terjadinya infeksi malaria. TNF-α berperan penting dalam respons imun pada malaria akut yang menghambat terjadinya eritropoesis. Penelitian ini bertujuan untuk mengetahui hubungan antara kadar TNF-α dengan kejadian anemia pada ibu hamil didaerah endemik malaria vivax. Penelitian ini menggunakan desain potong lintang, dilakukan pada bulan Januari - Februari 2014 di lima wilayah kerja puskesmas Kota Bengkulu. Sampel penelitian adalah ibu hamil di daerah endemis malaria vivax yang diambil secara accidental sampling. Dilakukan pengambilan darah untuk pemeriksaan mikroskopis malaria, kadar TNF-α dan kadar hemoglobin (Hb). Hasil penelitian menunjukkan seluruh ibu hamil memiliki riwayat pernah terinfeksi malaria vivax, walaupun hasil pemeriksaan slide negatif. Terjadi peningkatan kadar TNF- α dengan rerata 6,90 ± 2,48 pg/mL dan penurunan kadar Hb dengan rerata 9,75 ± 0,88 g%. Uji korelasi Spearman didapatkan korelasi negatif yang kuat (r = -0,734) dan bermakna (nilai p &lt; 0,05) antara Kadar TNF-α dengan kadar Hb. Terdapat hubungan yang bermakna antara kadar TNF-α dengan kejadian anemia.Tumor Necrosis Factor-α as Predictor of Anemia Occurrence among Pregnant Mothers in Malaria-Endemic AreasPregnant mothers living in malaria - endemic area are very susceptible to malaria infection during pregnancy. Malaria symptoms in this group are often asymptomatic or even not detected at all due to protective immunity effect through repeated infections. Any elevation of tumor necrosis factor-alpha (TNF-α) level can be used as indicator of malaria infection. TNF-α takes an important role in immune response on acute malaria that hinders occurence eritropoesis process. This study aimed to find out relations between TNF-α level and anemia occurrence among pregnant women living in malaria vivax - endemic areas. The study used cross-sectional design conducted on January to February 2014 in five working areas in Bengkulu city. Sample of study was pregnant mothers in malaria vivax - endemic areas which was taken through accidental sampling. Blood was taken for malaria-microscopic examination, TNF-α and haemoglobine (Hb) level. The results showed that all of pregnant mothers have malaria vivax - infected record, although slide examination showed negative result. Any TNF-α level elevation with average 6.90 ± 2.48 pg/mL and decrease of Hb level with average 9.75 ± 0.88 g%. Spearman correlation test showed strong negative correlation (r = -0.734) and significant (p value &lt; 0.05) between TNF-α level and Hb level. There was significant relation between TNF-α level and anemia occurrence.
Pengaruh Guided Imagery And Music Therapy Terhadap Kecemasan Pasien Pre Operasi Laparatomi Herlinda, Herlinda; Wahyuni, Dian; Flora, Rostika
Jurnal Keperawatan Sriwijaya Vol 2, No 1 (2015)
Publisher : Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Tujuan: Guided imagery and music (GIM) merupakan tindakan mandiri keperawatan yang mengombinasikan relaksasi bimbingan imajinasi dan musik. Penelitian bertujuan mengetahui pengaruh GIM terhadap kecemasan pasien pre operasi laparotomi di RSUD Dr. Ibnu Sutowo Baturaja. Metode: Penelitian ini menggunakan desain pre experiment dengan pendekatan pre and post test withthout control group design. Pengambilan sampel menggunakan purposive sampling dengan jumlah sampel sebanyak 25 responden. Instrumen penelitian yang digunakan berupa modifikasi kuesioner Taylor Manifest Anxiety Scale (T-MAS) dan Amsterdam Preoperative and Information Scale (APAIS). Analisis data yang digunakan adalah uji statistik non parametrik Wilcoxon. Hasil: Hasil penelitian menunjukkan bahwa ada pengaruh yang signifikan GIM terhadap kecemasan pre operasi laparotomi di RSUD Dr. Ibnu Sutowo Baturaja. Uji statistik Wilcoxon menunjukkan p value<0,05 (p value=0,001) dan Z hitung -3,746. Ada pengaruh yang signifikan antara GIM terhadap kecemasan pre operasi laparotomi di RSUD Dr. Ibnu Sutowo Baturaja. Simpulan: Implikasi penelitian diharapkan adanya penelitian dengan jumlah sampel yang besar dan dengan desain quasi eksperiment dengan pengontrolan terhadap variabel perancu yang lebih ketat. Kata Kunci: guided imagery and music, kecemasan, pre operasi, laparotomi
The Risk Quotient of Sulfide Hydrogen toward Lung Vital Capacity of People Living Around Landfill Area Zulkarnain, Mohammad; Flora, Rostika; Novrikasari, Novrikasari; Harto, Toto; Apriani, Dwi; Adela, Novita
Jurnal Kesehatan Masyarakat Nasional Volume 12, Issue 3, February 2018
Publisher : Faculty of Public Health Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (264.51 KB) | DOI: 10.21109/kesmas.v12i3.1302

Abstract

Waste is one of factors causing air pollution in Palembang City. Volume of waste that should be processed increases every day, while condition of waste management service is still 70% of the total volume. The waste processing is managed by using open dumping system, which affects on the increase of air pollution. One of gases that exist as effect of the process of organic compound decomposition of anaerobic bacteria from garbage is sulfide hydrogen (H2S) pollutant which can promote health disorders, especially respiratory system. This study aimed to analyze correlation between characteristics (age, sex, nutritional status, smoking, and living distance) and the risk quotient of sulfide hydrogen concentration in air ambient to the lung capacity of people around landfillarea. This study used cross-sectional design with the sample of 78 people around landfill area. Data analysis used double logistic regression. Results showed that nutritional status (p value = 0.022, OR = 12.085) and RQ (p value = 0.016; OR = 7.547) significantly related to lung vital capacity of people around landfill area. People around landfill area having worse nutrition and lower RQ than the median were potential to have lung vital capacity disorder. The dominant variable significantly influencing to lung vital capacity of people living around Sukawinatan Landfill is nutritional status.AbstrakSampah merupakan salah satu penyebab terjadinya polusi udara di Kota Palembang. Setiap hari terjadi peningkatan volume sampah yang harus diolah, sedangkan kondisi pelayanan pengelolaan sampah baru mencapai sekitar 70% dari total sampah secara keseluruhan. Pengolahan sampah yang dilakukan menggunakan sistem open dumping berdampak terhadap peningkatan terjadinya polusi udara. Gas hidrogen sulfida (H2S) yang diperoleh dari proses penguraian senyawa organik oleh bakteri anaerob pada tumpukan sampah dapat mengganggu kesehatan, terutama sistem pernapasan. Penelitian ini bertujuan untuk menganalisis hubungan antara karakteristik (usia, jenis kelamin, status gizi, merokok, dan jarak tempat tinggal) dan besaran risiko konsentrasi H2S udara ambien terhadap kapasitas vital paru penduduk di sekitar tempat pembuangan akhir (TPA) sampah. Penelitian ini menggunakan desain potong lintang dengan sampel 78 orang penduduk yang berada di sekitar TPA. Analisis data menggunakan uji regresi logistik ganda. Hasil menunjukkan nilai status gizi (nilai p = 0,022, OR = 12,085) dan RQ (nilai p = 0,016; OR = 7,547) berhubungan secara signifikan terhadap kapasitas vital paru penduduk yang berada di sekitar TPA. Penduduk yang berada di sekitar TPA dengan nilai status gizi buruk dan nilai RQ lebih rendah dari median berpotensi mengalami gangguan kapasitas vital paru. Variabel dominan yang secara signifikan memengaruhi kapasitas vital paru penduduk yang berada di sekitar TPA sampah Sukawintan adalah status gizi.
PELATIHAN SENAM KAKI PADA PENDERITA DIABETES MELLITUS DALAM UPAYA PENCEGAHAN KOMPLIKASI DIABETES PADA KAKI (DIABETES FOOT) Flora, Rostika
Jurnal Pengabdian Sriwijaya Vol 1, No 1 (2013)
Publisher : Jurnal Pengabdian Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Senam kaki merupakan latihan yang dilakukan bagi penderita Diabetes Melittus (DM) atau bukan penderita untuk mencegah terjadinya luka dan membantu melancarkan peredaran darah bagian kaki.Perawat sebagai salah satu tim kesehatan, selain berperan dalam memberikan edukasi kesehatan juga dapat berperan dalam membimbing penderita DM untuk melakukan senam kaki sampai dengan penderita dapat melakukan senam kaki secara mandiri. Kegiatan Pengabdian Masyarakat dengan judul ”Pelatihan Senam Kaki Pada Penderita Diabetes Mellitus Dalam Upaya Pencegahan Komplikasi Diabetes Pada Kaki (Diabetes Foot)” telah dilaksanakan.di desa Indralaya Mulya. Dari kegiatan ini dapat disimpulkan bahwa seluruh peserta (100%) mengetahui tujuan dilakukannya senam kaki, mengetahui manfaat senam kaki, mengetahui indikasi dan kontraindikasi senam kaki dan antusias, perhatian serta aktif selama kegiatan pelatihan senam kaki.