Agus Firmansyah
Prodi D III Keperawatan Fakultas Ilmu Kesehatan, Universitas Pesantren Tinggi Darul Ulum Jombang
Articles
49
Documents
Scoring System for Helicobacter pylori Infection in Children with Recurrent Abdominal Pain

Journal of the Indonesian Medical Association Vol. 62 No. 8 August 2012
Publisher : Journal of the Indonesian Medical Association

Show Abstract | Original Source | Check in Google Scholar

Abstract

Introduction: Helicobacter pylori (H. pylori) infection is estimated to strike half the world’s population. However, the diagnostic tool for H. pylori infection remains expensive and scarce. Thus, a simple diagnostic method is required in places with limited resources. This study aims to assess the diagnostic values of scoring system for H. pylori infection in children presenting with recurrent abdominal pain (RAP). Methods: This is a diagnostic study with a cross sectional design on 196 children aged 6-18 years who presented with RAP. This study was conducted in Bandung, January-November 2009. The scoring system was developed based on a questionnaire on complaints related to H. pylori infection. As the gold standard, a non-invasive examination with high accuracy was used, a serological kit BioM pylori (Mataram local antigen).The diagnostic values were assessed by the area under the receiver operating characteristic (ROC) curve. Result: The prevalence of H. pylori infection in children presenting with RAP is 54.6% (95% CI: 47.6 - 61.6%). After performing bivariate and multivariate analyses, 11 questions were used on the final questionnaire. Based on the ROC curve, a cut-off point of score > 30 was obtained, with a  88.5% sensitivity and 88.2% specificity. Conclusion: The scoring system can be used to predict H.pylori infection in children aged 6-18 years who presented with RAP. Key words: Helicobacter pylori, recurrent abdominal pain, scoring system, children

HUBUNGAN GIGI KARIES TERHADAP STATUS GIZI ANAK TK ,TK MUSLIMAT 7 PETERONGAN JOMBANG

Eduhealth Vol 3, No 1 (2013): Jurnal Eduhealth
Publisher : Eduhealth

Show Abstract | Original Source | Check in Google Scholar

Abstract

ABSTRAKKaries  gigi atau pembusukan gigi adalah suatu kerusakan deskruktif progresif dan mengenai jaringan-jaringan  gigi  yang  mengalami  pengapuran.  Karies  gigi  merupakan  masalah  mulut utama  pada  anak-anak.  Rasa  timbul  tidak  nyaman  pada  orang  yang  menderita  gigi  karies menimbulkan  dampak  pada  status  gizi  anak.  Rancangan  penelitian  ini  menggunakan  cross sectional. Dengan jumlah populasi  29 anak dan sampel yang di gunakan sejumlah 27 anak di TK Muslimat 7 Peterongan Jombang, dengan menggunakan teknik simple random sampling. Pengumpulan  data  dengan  menggunakan  lembar  observasi  yang  didalamnya  terdapat beberapa  komponen  yaitu  tabel  tingkat  karies  gigi  dan  komponen  z-score  tabel,  Uji  analisa menggunakan  Spearman’s  corelation  dengan  α  <  0,05.  Hasil  penelitian  ini  menunjukkan bahwa  hubungan  karies  gigi  terhadap  status  gizi  anak  sebagian  besar  yang  menderita  karies berstatus  gizi  buruk  atau  kurus  sebanyak  21  responden  (77,8%),  selain  itu  dari  hasil menggunakan Spearman’s corelation didapatkan α = 0,00 dengan koefesien korelasi r = 0,869 yang berarti ada hubungan antara gigi karies dengan status gizi anak  di Kelas A TK Muslimat 7 Peterongan Jombang yang sangat kuat..Kata Kunci : karies Gigi,  status GiziABSTRACTDental  caries  or  tooth  decay  is  a  progressive  and  deskruktif  damage  on  dental  tissues  that had  calcification. Dental  caries  is  the  main  oral  problems  in  children. Sense  of  discomfort arisingin  people  who  suffer  from  dental  caries  have  an  impact  on  nutritional  status  of children. The design of this study using cross sectional. With a population of 29 children and a  sample  that  is  in  use  a  number  of  27  children  in  kindergarten  Muslimat  7  Peterongan Jombang, using simple random sampling technique as sampling methode. Data collection by using the observation sheet in which there are several components of the table level of dental caries and z-score table components, test analysis using Spearman´s corelation with α <0.05. The  results  of  this  study  indicate  that  dental  caries  relationship  to  the  nutritional  status  of children who suffer most of the caries status of malnourished or underweight as many as 21 respondents (77.8%), other than that of the results obtained using the Spearman´s corelation α  =  0.00  with  a  correlation  coefficient  r  = 0.869,  the  powerful  which  means  there  is  a relationship  between  dental  caries  in  the  nutritional  status  of  children  in  kindergarten Muslimat 7 Class A Peterongan Jombang.  Key words: dental Caries, nutrition Status

Elastase-1 concentration in feces of term and preterm infants aged 0 – 4 months

Medical Journal of Indonesia Vol 12, No 2 (2003): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Original Source | Check in Google Scholar

Abstract

Fecal elastase-1 concentration reflects exocrine pancreatic function. There have been some reports from Europe, but so far there has not been a report of fecal elastase-1 concentration in Indonesia, especially concerning infants. The aim of this study is to know the concentration of elastase-1 in feces of infants aged 1-120 days as a preliminary report of the study of the ontogeny of pancreatic elastase-1 in term and preterm infants. Fecal elastase-1 were measured from feces of 28 healthy preterm and 34 healthy term infants up to 120 days (4 month) of age. Elastase-1 concentration in infants less than 14 days of age fluctuated below 200 μg/gram feces. At the first day of life 80% preterm and 60% term infants had elastase-1 concentration less than 200 μg/gram feces, and by the age of 7 days 50% preterm and 33% term infants had elastase-1 concentration less than 200 μg/gram feces. After 14 days of age its concentration was more than 200 μg/gram feces, regardless of gestational age. This preliminary study corroborates supported the previous studies that the level of fecal elastase-1 reached normal level after 14 days. Future longitudinal study is needed to know elastase-1 concentration in infants less than 14 days. (Med J Indones 2003; 12: 69-72) Keywords: Fecal elastase-1, Infants, Enzyme-link immunosorbent assay

Effects of realimentation on small intestinal morphology and disaccharidase activity in malnutrition Sprague-Dawley rats

Medical Journal of Indonesia Vol 15, No 4 (2006): October-December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Original Source | Check in Google Scholar

Abstract

Low birth-weight infant and intrauterine growth retardation are still a health problem, especially in Indonesia due to high prevalence and need to be reduced. Malnutrition in infants are most common occur in low birth-weight infants. Malnutrition in rats resulted in hypotrophic and normoplastic mucosa of the small intestine. The finding was not only showed that small intestine was able to maintain its cell number in condition with restriction nutrient, however also suggested the posibility of epithelial regeneration if given adequate nutrient intake. Did realimentation recover the hypotrophic normoplastic mucosa to normotrophic normoplastic? The study aim to answer that question. Experimental animal study with post test-control group design was performed using 40 male litter of Sprague-Dawley rats, was fed standard chow. The study was divided into phases prenatally-induced malnutrition and continued with phase realimentation. The result of this study is the body weight, mucosal thickness, villus height, cryptus depth, ratio of villus/ crypt, number of villi, protein content, and disaccharidases of rats realimentation group was higher than non-realimentation group, but lower than control group. Prenatally-induced malnutrition did not reduced the population of small intestinal enterocytes. Realimentation in rats in prenatally-induced malnutrition was able to improve the hypotrophy of small intestinal mucosa and to increase the disaccharidases activities but did not reach the normal values. Realimentation in rats in prenatally-induced malnutrition was able to improve the maturity of small intestine mucosa but did not reach the normal values. The information will be helpfull to decide the policy of maternal malnutrition. (Med J Indones 2006; 15:208-16)Keywords: small intestinal morphology, disaccharidase activity, Sprague-Dawley rats, prenatally-induced malnutrition, realimentation.

Upper Gastrointestinal Endoscopy and Histopathology Appearance in Indonesian Children with Recurrent Epigastric Pain

The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 8, ISSUE 3, December 2007
Publisher : The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy

Show Abstract | Original Source | Check in Google Scholar

Abstract

Background: Recurrent Epigastric Pain (REP) is a clinical symptom frequently found in children. Data of the correlation between duration of illness, frequency of illness, associated symptoms of REP and the abnormality of endoscopic and histopathologic appearance are still limited, especially in Indonesia. The role of Helicobacter pylori (H. pylori) infection in causing organic abnormalities of the gastrointestinal tract (GIT) is also still controversial. Aim:To know the endoscopic and histopathologic appearance and the prevalence of Helicobacter pylori infection, 169 children with REP was performed for endoscopic and histopathologic examination in Department of Pediatric, Cipto Mangunkusumo hospital. Result:Endoscopic and histopathologic abnormalities were found significantly in children who suffered from REP more than 9 months and more than 6 times during 3 months of period. Conclusion: Endoscopic and histopathologic examinations should be considered in children with REP. Keywords: recurrent abdominal pain, epigastric pain, Helicobacter pylori, endoscopy and histopathology

The Role of Supporting Examinations on the Diagnosis of Chronic Diarrhea in Children

The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 8 ISSUE 2 August 2007
Publisher : The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy

Show Abstract | Original Source | Check in Google Scholar

Abstract

Background: Etiology of chronic diarrhea can be established through non-invasive examination such as stool examination and stool culture. Colonoscopy is an invasive Method, which is occasionally needed to discover the etiology of chronic diarrhea. Objective: To recognize the characteristics of chronic diarrhea based on stool examination and colonoscopy results. Methods: Descriptive study on patients with chronic diarrhea who came to Cipto Mangunkusumo hospital since 1 June to 31 August 2005. Laboratory tests were conducted in accordance with clinical indication. Data was presented in distribution tables. Results: There were 41 patients with chronic diarrhea. Stool examination were performed only in 38 patients with negative-gram infection (86.8%). Stool cultures were performed in 27 patients with positive results of non-pathogenic Escherichia coli (85.2%). Stool parasite examination and concentration tests were performed in 17 patients, with 47.0% positive results as follow: Microsporidia 29.4%, Blastocystis hominis 11.8% and Giardia lamblia 5.9%. Colonoscopy examinations were performed in 6 patients and all patients indicated ulcerative colitis appearance with 50% histopathological impression of infective colitis. Conclusion: Stool examination in chronic diarrhea primarily indicates positive infection. Bacterial stool culture mostly includes non-pathogenic Escherichia coli, while parasite stool examination largely includes Microsporidia. Biopsy examination tends to reveal infective colitis. Keywords: chronic diarrhea, parasite stool, colonoscopy

Quantitative analysis of lactose and lactulose in urine by high performance liquid chromatography for determination of intestinal lactase activity

Medical Journal of Indonesia Vol 12, No 1 (2003): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Original Source | Check in Google Scholar

Abstract

Determination of intestinal lactase activity is directly done by measuring its activity in intestinal epithelium. This is an invasive method and ethically can not be done in healthy infants. Indirectly, determination of lactase activity, stated as excretion and ingestion ratio of lactose and lactulose, needs 30 hours hospitalized infants. The aim of this study was to look for a method for determination of lactase activity which is not invasive and not necessary hospitalized. Using this method  lactose and lactulose were given as a single oral load after 2 hours fasting. Urine were collected for 5 hours starting from consuming sugar solution and then lactose and lactulose concentration in the urine were measured by High Performance Liquid Chromatography. The results showed single oral load of lactose and lactulose can be used for determination of lactase activity in infant and the infants were observed only for 7 hours. (Med J Indones 2003; 12: 8-12) Keywords: Lactase activity, Lactulose, Lactose, High Performance Liquid Chromatography

Faktor yang Berhubungan dengan Hiperglikemia dan Luarannya pada Anak Sakit Kritis

Sari Pediatri Vol 15, No 1 (2013)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Original Source | Check in Google Scholar

Abstract

Latar belakang. Hiperglikemia pada sakit kritis berhubungan dengan luaran yang lebih buruk, seperti lama penggunaan ventilasi mekanik, dan obat vasoaktif lebih panjang, serta derajat disfungsi organ yang lebih berat.Tujuan. Mengetahui hubungan karakteristik subjek dengan hiperglikemia serta mengetahui perbedaan proporsi subjek yang mengalami hiperglikemia antara kelompok subjek yang memakai ventilasi mekanik, mendapat obat vasoaktif, serta dengan disfungsi organ berat, dibandingkan dengan kelompok subjek yang tidak.Metode. Studi analitik potong lintang dilakukan pada anak sakit kritis di Pediatric Intensive Care Unit (PICU) Rumah Sakit Cipto Mangunkusumo (RSCM) usia 1 bulan-18 tahun, dilakukan antara Maret-Juni 2011.Hasil. Didapatkan 87 subjek penelitian, 60 di antaranya laki-laki. Hiperglikemia ditemukan pada 25/87 (28,7%) subjek dengan median kadar glukosa darah 121 (37-443) mg/dL Hiperglikemia ditemukan lebih banyak pada laki-laki, usia >1-5 tahun, gizi kurang, dan pasca-bedah, tetapi tidak ditemukan hubungan yang bermakna. Subjek yang menggunakan ventilasi mekanik dan vasoaktif memiliki proporsi lebih besar mengalami hiperglikemia dibandingkan dengan subjek yang tidak, tetapi perbedaan ini juga tidak bermakna. Enam dari 10 subjek yang memiliki skor Pediatric Logistic Organ Dysfunction (PELOD) tinggi mengalami hiperglikemia. Proporsi ini lebih besar dibandingkan subjek dengan skor PELOD rendah, yaitu 19/77 subjek (p=0,03).Kesimpulan. Proporsi subjek yang mengalami hiperglikemia lebih besar pada anak dengan disfungsi organ berat daripada disfungsi organ ringan. Karakteristik subjek tidak berhubungan dengan hiperglikemia pada sakit kritis. Tidak terbukti adanya perbedaan proporsi subjek yang mengalami hiperglikemia pada anak sakit kritis yang menggunakan ventilasi mekanik dan obat vasoaktif dibandingkan dengan kelompok subjek yang tidak.

Pola Defekasi pada Anak

Sari Pediatri Vol 3, No 3 (2001)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Original Source | Check in Google Scholar

Abstract

Defekasi merupakan salah satu aktivitas manusia yang harus dilalui di dalam kehidupansehari-harinya. Pola defekasi pada anak sangat bervariasi dan sangat bergantung padafungsi organ, susunan saraf, pola makan, serta usia anak. Menilai pola defekasi padaanak berarti menilai frekuensi defekasi, konsistensi dan warna tinjanya. Berdasarkanpenelitian yang telah dilakukan di beberapa negara di Amerika, Eropa, dan Asia-Pasifikdiketahui bahwa terjadi penurunan frekuensi defekasi sesuai dengan bertambahnya usiaanak, sedangkan perubahan konsistensi dan warna tinja sesuai dengan pola makan. Sejauhini belum pernah dilaporkan tentang pola defekasi pada anak Indonesia.

Pemantauan pH Esofagus pada Bayi Tidak Mempengaruhi Aktivitas dan Pola Makan, Namun Mengkhawatirkan Persepsi Orangtua

Sari Pediatri Vol 8, No 4 (2007)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Original Source | Check in Google Scholar

Abstract

Latar belakang. Pemantauan pH esofagus (pH-metri) merupakan pemeriksaan bakuuntuk mendiagnosis refluks gastroesofagus (RGE) pada bayi. Hasil pH-metri dipengaruhioleh pola makan dan aktivitas bayi, sedangkan pengaruh prosedur pH-metri itu sendiriterhadap pola makan dan aktivitas bayi belum banyak dilaporkan.Tujuan. Tujuan penelitian ini untuk mengetahui apakah prosedur pH-metrimempengaruhi pola makan dan aktivitas sehari-hari serta bagaimana persepsi orangtuaterhadap prosedur pH-metri.Metoda. Tiga puluh bayi berumur 6-12 bulan dilakukan pH-metri. Orangtua diberikuesioner berisi pertanyaan yang berhubungan dengan pola makan dan aktivitas anakselama pemantauan berlangsung serta persepsi orangtua terhadap prosedur pH-metri.Untuk analisis statistik, setiap variabel dikelompokkan menjadi ’tidak berubah’ dan’berubah’ untuk pola makan dan aktivitas anak, serta ’positif’ dan ’negatif’ untuk persepsiorangtua. Setiap variabel dianalisis berdasarkan hasil pH-metri (’normal’ atau abnormal’).Hasil. Perubahan pola makan terdapat pada 17% bayi sedangkan perubahan aktivitaspada 20% bayi. Kedua hasil tersebut tidak berbeda baik pada hasil pH-metri normalmaupun hasil pH-metri abnormal. Dua puluh tujuh persen orangtua mempunyai persepsipositif terhadap prosedur pH-metri.Kesimpulan. Prosedur pH-metri tidak menyebabkan perubahan pola makan danaktivitas bayi, walaupun demikian hanya sekitar 27% orangtua yang menganggapprosedur pH-metri sebagai prosedur yang tidak mengkhawatirkan.

Co-Authors Abdul Ghofar Adi Suryanto B, Adi Suryanto Agnes Kurniawan Ali Sungkar Alifiani H. Putranti, Alifiani H. Aman B. Pulungan Anita Juniatiningsih Asri Rasad Asril Aminullah Aswitha Boediarso, Aswitha Aswitha Boediharso Aswitha D Boediarso, Aswitha D Aswitha D. Boediarso, Aswitha D. Badriul Hegar Badriul Hegar Syarif, Badriul Hegar Bambang Madiyono Bambang Tridjaja, Bambang Bobby Setiadi Dharmawan, Bobby Setiadi Budi, Lenny S. Budiwardhana, Novik Bulan Ginting Munthe, Bulan Ginting Clara M Kusharto Daldiyono Harjodisastro Daniel Effendi, Daniel Darlan Darwis, Darlan Deddy S Putra Dewanto, Naomi E.F. Dwi Prasetyo Dwirini Retno Edi S Tehuteru, Edi S Edi S. Tehuteru, Edi S. Edward Surjono, Edward Elizabeth Yohmi, Elizabeth Endi Ridwan F M Susanto Fajar Subroto, Fajar Fatima Safira Alatas, Fatima Safira H. S. Moeslichan MZ, H. S. Moeslichan Hardinsyah . Hardiono D Pusponegoro, Hardiono D Hasri Salwan, Hasri Hendrawati, Lilis D. Herbowo A. Soetomenggolo Herbowo Herbowo, Herbowo Herman Suryadi Herry Garna Hindra Irawan Satari, Hindra Irawan IGN Sanjaya Putra Imral Chair, Imral Irawan Mangunatmadja, Irawan Jahja Umar, Jahja Jose R. L. Batubara, Jose R. L. Mardjanis Said, Mardjanis Mulyadi M Djer, Mulyadi M Mulyadi M. Djer Murti Andriastuti, Murti Muzal Kadim Najib Advani Nani Dharmasetiawani Partini P Trihono, Partini P Partini P. Trihono, Partini P. Ponpon Idjradinata Pramita G D Pramita G Dwipoerwantoro, Pramita G Pramita G. Dwipurwantoro, Pramita G. Pramita GD, Pramita Pramitra Gayatri, Pramitra Pulungsih, Sri P Pustika Amalia Rina Rahardiani, Rina Risatianti Kolopaking, Risatianti Riza Mansyoer, Riza Rosary Rosary, Rosary Rulina Suradi, Rulina Rustadi Sosrosumihardjo Sadikin, Hartaniah Saptawati Bardosono Septilia I. Wanandi Septilia Inawati Wanandi, Septilia Inawati Setia Budi Setyo Handryastuti, Setyo Siti B. Kresno Siti Budiati Widyastuti, Siti Budiati Soedjatmiko Soedjatmiko Soedjatmiko, Soedjatmiko,, Soedjatmiko, Soepardi Soedibjo Sri Lestari Sri Rezeki Hadinegoro, Sri Rezeki Sri Rezeki S Hadinegoro, Sri Rezeki S Sudigdo Sastroasmoro Susanti, Nuraini I Taralan Tambunan Teny Tjitrasari, Teny Theresia Theresia Tri Sunarti Wahyutami, Tri Sunarti Trina Astuti Tuty Rahayu, Tuty Umi Fahmida Wan Nedra, Wan Widodo, Dwi P. Winny N Wishwadewa, Winny N Yati Soenarto Zakiudin Munasir