Yuni Astria
General Practitioner on Internship Program, Faculty of Medicine, Universitas Indonesia, Jakarta

Published : 4 Documents

Found 4 Documents

Metabolic syndrome and Framingham risk score in obese young adults Widjaja, Felix F.; Widjaja, Ivan R.; Astria, Yuni; Suwita, Christopher S.; Waspadji, Sarwono
Medical Journal of Indonesia Vol 22, No 2 (2013): May
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (391.682 KB) | DOI: 10.13181/mji.v22i2.536


Background: The increase number of the metabolic syndrome (MetS) among young adults was mostly caused by obesity. MetS increases the risk of coronary heart disease (CHD) which can be estimated by Framingham risk score (FRS). The study was aimed to know the prevalence of MetS and FRS in obese young adults and to associate them with the components of MetS. Methods: A total of 70 male and female students aged 18 to 25 years with BMI ≥ 25 kg/m2 in Faculty of Medicine Universitas Indonesia were selected consecutively. The blood samples used to test fasting blood glucose, total cholesterol, high-density lipoprotein, and triglyceride were examined in Department of Clinical Pathology, Cipto Mangunkusumo Hospital after fasting for 14 to 16 hours. International Diabetes Federation (IDF) definition was used to diagnose MetS. Univariate and bivariate analysis were done. Results: The prevalence of MetS based on IDF definition was 18.6% among obese young adults. The most associated MetS components was hypertriglyceridemia (OR 12.13; 95% CI 2.92-50.46; p = 0.001), followed with high blood pressure (OR 9.33; 95% CI 2.26-38.56; p = 0.001), low-HDL (OR 8.33; 95% CI 2.17-32.05; p = 0.003), and impaired fasting glucose (p = 0.03). Four subjects had FRS ≥ 1% and 66 subjects had risk < 1%. Increased FRS was not associated with MetS (p = 0.154). There was no component of MetS associated with increased FRS. Conclusion: Prevalence of MetS in obese young adults was similar with obese children and adolescents. Although no association of MetS and FRS was found, they are significant predictors for CHD which should not be used separately. (Med J Indones. 2013;22:100-6)Keywords: Abdominal obesity, Framingham risk score, metabolic syndrome, young adults
Gastro-esophageal reflux disease among type-2 diabetes mellitus patients in a rural area Suwita, Christopher S.; Benny, Benny; Mulyono, Daniel R.; Rosani, Selti; Astria, Yuni; Widjaja, Felix F.; Syam, Ari F.
Medical Journal of Indonesia Vol 24, No 1 (2015): March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (445.145 KB) | DOI: 10.13181/mji.v24i1.1164


Background: One of the most neglected complications of diabetes mellitus (DM) is gastro-esophageal reflux disease (GERD) which arises from autonomic neuropathy and diabetic gastropathy related to the extent of DM. This study was done to find prevalence of GERD in DM patients with GERD-questionnaire (GERDQ), dietary factor proportion, and their association with other GERD risk factor in rural area. Methods: This cross sectional study was conducted in Puskesmas Pelaihari from August to September 2013. Subjects with DM aged ≥ 18 were selected consecutively from both newly and previously diagnosed patients with exclusion criteria: pregnancy, in proton-pump inhibitor therapy, and had other metabolic disease(s). DM was diagnosed with ADA criteria, while GERD was diagnosed in patients with score of ≥ 8 of Indonesian GERDQ. Results: There were 30 subjects (29.7%) with GERD among 101 patients with DM and dietary factors found in GERD patients were spicy diet (90%), high-fat food (90%), irritative beverages (87%), and irritative diet (23%). Only female gender was associated with GERD vs non-GERD in DM patients (87% vs 68%, p = 0.048). Meanwhile, duration of DM (2 [0-13] vs 2 [0-19], p = 0.976), obesity (37% vs 38%, p = 0.897), age (53.2±10.5 vs 54.7 ± 9.3, p = 0.481), and uncontrolled diabetes (90% vs 94%, p = 0.421) were not associated with the GERD among DM patients.Conclusion: Prevalence of GERD in DM is somewhat high in this study. Female group with DM needs to be screened for GERD as early as possible.
Low birth weight profiles at H. Boejasin Hospital, South Borneo, Indonesia in 2010-2012 Astria, Yuni; Suwita, Christopher S.; Suwita, Benedica M.; Widjaja, Felix F.; Rohsiswatmo, Rinawati
Paediatrica Indonesiana Vol 56 No 3 (2016): May 2016
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (375.603 KB) | DOI: 10.14238/pi56.3.2016.155-61


Background The prevalence of low birth weight (LBW) is still high in Indonesia. Intrauterine growth restriction (IUGR) and prematurity are the most frequent causes. Prematurity has higher mortality rate. Cultural diversity has an impact on regional LBW profiles in Indonesia. However, data on LBW is unavailable in South Borneo.Objective To describe the LBW profiles and in-hospital mortality of newborns at H. Boejasin Hospital, South Borneo.MethodsThis was a cross-sectional study using secondary data from medical records and neonatal registry at H. Boejasin Hospital, Pelaihari, South Borneo from 2010 to 2012. Subjects were newborns with birth weight <2,500 grams. Categorical data was presented in percentages, while survival analysis was assessed by Kaplan-Meier test. The difference among groups was analyzed with log-rank test.Results The proportion of LBW was 20.2% of total live births and the mortality rate was 17.3%. Mortality rates according to birth weight category was 96% in <1000 g group, 62% in 1,000-1,499 g group, 19% in 1,500-1,999 g group, and 4% in 2,000-2,499 g group. The highest hazard ratio was in the <1,000 gram birth weight group (HR 40.21), followed by the 1,000-1,499 gram group (HR 12.95), and the 1,500-1,999 gram group (HR 4.65);(P<0.01). Asphyxia, hyaline membrane disease (HMD), and sepsis were the most common causes of mortality (at 50%, 21%, and 16%, respectively).Conclusion The prevalence of LBW in this study is quite high and mortality of LBW infants is significantly different between each low birth weight category. [Paediatr Indones. 2016;56:155-61.].

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Penelitian tentang optimasi proses diazotasi untuk penentuan Chloramphenicol secara Spektrofotometri UV-Vis telah dilakukan. Tujuan dari penelitian ini adalah membentuk garam diazonium dengan Sulfanilamid sebagai sumber garam diazonium dan direaksikan dengan asam nitrit diikuti dengan proses diazotasi serta dikopling dengan Chloramphenicol. Hasil penelitian ini adalah terbentuknya senyawa azo berwarna kuning jernih yang dapat diukur pada panjang gelombang 400,941 nm. Senyawa ini stabil apabila direaksikan pada temperatur di bawah 10°C. Kondisi optimum dapat diperoleh dengan melakukan proses diazotasi menggunakan 3 mL Sulfanilamid, 3 mL HCl dan 6 mL NaNO2 serta waktu pengoplingan untuk pembentukan senyawa azo selama 8 menit.   Kata Kunci: Chloramphenicol, Sulfanilamid, diazotasi, Spektrofotometri UV-Vis.