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Journal : Program Kreativitas Mahasiswa - Penelitian

GELAS KAYU BIDARA LAUT (GEYU BILUT) SEBAGAI ANTIMALARIA

Program Kreativitas Mahasiswa - Penelitian PKM-P 2014
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

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Abstract

Malaria until now still remain one of the main problem of world health. About 40% or 2.4 billion people in the world live in malaria endemic areas. Therefore, malaria cases in Indonesia on 2008 is about 1.624.930 cases. More than 25% province in Indonesia shows resistence to sulfadoksin-pirimetamin, cloroquin and kina in the last decade. People of  NTB believes that stewed water of geyu bilut works as antimalaria. The purpose of this research is to know the effectivity of stewed water of geyu bilut as antimalaria. The research that had been done is an experimental research using post test only control group design. The research sample are 30 Balb/c mice that have fullfiled inclusion criteria and have been selected by using simple random sampling. Every sample was infected with 200µL P.berghei intraper-itoneally on day 0. Treatment start given with sondage 2-4 hours after infection, the treatment are 0.3ml aquades to negative control group, 0.3ml cloroquin with dose 5 mg/kgBW to positive control group and 0.3ml of stewed water of geyu bilut with concentration 0,0003% to the treatment group, the dose start given with orally once per day, from day 0 to day 7. The thin blood smear was made on day 1 to 8 and was checked by using light microscope with total magnify 1000x, percentage of parasitemia was counted per 1000 erythrocytes. Primary data that has been collected then processed using Kruskal Wallis Test. The result that was collected from stewed water of geyu bilut with dose based on empiric fact has parasitemia percentage that don’t have significant difference with negative control and positive control group (p>0,05). Therefore, from this research we can conclude that 0,3ml stewed water of geyu bilut with concentraion 0.0003% is not effective as antimalaria. Keywords: malaria, parasitemia percentage, geyu  bilut, Strychnos ligustrina BI.

Co-Authors AB, Amhar Abdi Sukmono, Abdi Abdul Haris Abdullah Abdullah Abdur Rauf, Abdur Achmad Ramadhan Afana Riesma Ila’la, Afana Riesma Agustin, Rena Denya Akor Sitepu Alamsyah, Zico Albeta, Sri Wilda Almuqsith, Leda Anas Puri, Anas Andi Alimuddin Unde, Andi Alimuddin Arriza, Isgi Asep Saputra Basri, Muthiara Budi Indra Setiawan Chaerunnimah, Chaerunnimah Chahyadi, Agus Chairul Irawan Chusnul Arif Cut Aida Fitri Dahlia Dahlia Dahnial Syauqy, Dahnial Defri Yoza Denny Widhiyanuriyawan Dewangga, Anisa Sutra Dian Widi Astuti, Dian Widi Diana Lisa Dirgantara, Yudi Erina Erina Evie Awuy Fahmi Amhar Fatimah Zuhrah, Fatimah Fiftin Noviyanto Fitri Diana Wulansari Fritz Akhmad Nuzir Furqon, Arif Al Gandung Sugita Hadi, Suryadi Hafied Cangara, Hafied Halin, Hamid Hamdan Sugilar Hartinah Hartinah Hasby Syarifuddin Masyhuri, Hasby Syarifuddin Hasniar Hasniar, Hasniar Herdini Herdini Hernina, Revi HI. MOH. SALEH, HUSEIN Hidayat, M N Hidayati, Baiti Idris, Andi Puspa Sari INDRAYANI INDRAYANI Irwan Dinata Isamu, Kobajashi Togo Jadid, Ahyar K. BIDIN, CICI RIANTY Kardono Kardono Kastutara, Dyan Khaerani Kiramang Krisnanto, Feri Krissandi Wijaya Mardhia, Murein Miksa Marice Pangaribuan Mizoguchi, Masaru Muhamad Taher MUHAMMAD ALI Muhammad Arsyad Suyuti Muhammad Fachri Muhammad Ramdhan Muhammad Rijal Munarso, Deka Trisnadi Musta, Rustam Mutmainnah Mutmainnah Nadimin Nadimin, Nadimin Naisya Hanan, Naisya Ni Putu Galuh Megantari Ekaputri, Ni Putu Galuh Nugraha, Muhammad Didik Nugroho, Nanang Agung Nurlansi, Nurlansi Oktavianus Prayitno, Oktavianus Patadjai, Andi Besse PERNANDO, Pernando Purnamasari, Endah Dewi Purnami Purnami Purwoko H Kuncoro, Purwoko H Putra, Aji Eka Putri Rieski Imanda, Putri Rieski Rafika Ratik Srimurni, Rafika Ratik Rainarli, Ednawati Ramadhani Yanidar, Ramadhani Rasmiwetti Rasmiwetti, Rasmiwetti Reza Kusuma Nurrohman, Reza Kusuma Rinitha Dinda Safitri, Rinitha Dinda Riyadi, Tofa Rokhmatuloh, Rokhmatuloh Rosmaniar Gailea Sahidin I, Sahidin Sahirman, Sidharta Saleh, Husein Hi. Moh Samsugi, Selamet Sapto Raharjo Sariyanti, Siti Sawitri Subiyanto Sedarmayanti, Sedarmayanti Seniati Seniati, Seniati Sinarmata, Pradha Wihandi Siti Ulfatun Najiyyah, Siti Ulfatun Sri Handayaningsih Sudirman Husin Sumarni, Eni Sumarni Sumirat, Yan Suryo Suseno, Weling Syaharuddin Rasyid Syukur, Idris Taku Nishimura, Taku Tibyani Tibyani, Tibyani Triantoro, Dony Arung Tristiyanto Tristiyanto, Tristiyanto Vitayanti Fattah, Vitayanti Wahri Sunanda Wamilliana, Wamilliana Wicaksono, Viriya Widya Cahyadi, Widya Yossi Oktorini Yulius Yulius Yuliza Yuliza Yusuf Kendek Yusuf Kendek Paluin Zul, Khairi Zulhelmi Zulhelmi, Zulhelmi Zulkarnain, Faris