Nanik Siti Aminah
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Airlangga University, Kampus C UNAIR Jl. Mulyorejo Surabaya, 60115

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Modification of Turen Bentonite with AlCl3 for Esterification of Palmitic Acid Abdulloh, Abdulloh; Maryam, Siti; Aminah, Nanik Siti; Triyono, Triyono; Trisunaryanti, Wega; Mudasir, Mudasir; Prasetyoko, Didik
Bulletin of Chemical Reaction Engineering & Catalysis 2014: BCREC Volume 9 Issue 1 Year 2014 (SCOPUS Indexed, April 2014)
Publisher : Department of Chemical Engineering - Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.9767/bcrec.9.1.5513.66-73

Abstract

Natural Turen bentonite has been modified and applied as catalyst for palmitic acid esterification. Modification of natural Turen bentonite was conducted by cation exchange method using AlCl3 solution. Catalyst characterization was performed on X-ray Fluoroscence, X-ray Diffraction, nitrogen adsorption-desorption and infrared spectroscopy techniques. The catalytic activity test in the esterification reaction of palmitic acid with methanol was conducted by bath at 65 °C with a variation of reaction time of 1, 2, 3, 4 and 5 h. Catalytic activity has been observed qualitatively using GC-MS and quantitatively by changes in acid number. The analysis showed the formation of Al3+-bentonite. Observation on the elements has shown that the presence of calcium decreased from 10.2% to 4.17%, with an increase of aluminium content from 9.9% to 13%. Diffraction line at 2θ 5.7379º became 5.6489º, along with changes in d-spacing of 15.3895 Å to 15.6319 Å. The surface area increased from 83.78 m2/g to 91.26 m2/g, while Brönsted acid sites increased from 10.2 µmol/g to 67.5 µmol/g and Lewis acid sites increased from 94.9 µmol/g to 132 µmol/g. Furthermore, Al3+-bentonite has showed as active catalyst in the esterification reaction of palmitic acid with palmitic acid with conversion of 78.78% for 5 h. © 2014 BCREC UNDIP. All rights reservedReceived: 24th September 2013; Revised: 31st December 2013; Accepted: 26th January 2014[How to Cite: Abdulloh, A., Maryam, S., Aminah, N.S., Triyono, T., Trisunaryanti, W., Mudasir, M., Prasetyoko, D. (2014). Modification of Turen’s Bentonite with AlCl3 for Esterification of Palmitic Acid. Bulletin of Chemical Reaction Engineering & Catalysis, 9 (1): 66-73. (doi:10.9767/bcrec.9.1.5513.66-73)][Permalink/DOI: http://dx.doi.org/10.9767/bcrec.9.1.5513.66-73]
ANTIOXIDANT ACTIVITY OF METHANOL EXTRACTS FROM THE STEM BARK OF MANGROVE PLANT Rhizophora mucronata Mahmiah, Mahmiah; Giman, Giman; Aminah, Nanik Siti; Tanjung, Mulyadi
UNEJ e-Proceeding 2016: Proceeding of 1st International Conference on Medicine and Health Sciences (ICMHS)
Publisher : UNEJ e-Proceeding

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Numbers of diseases such as stroke, diabetes, gout,and even cancer are caused by the reaction of freeradicals (oxidants) found in the body. Those diseasescurrently have not yet controlled. Deleteriouslifestyle, lack of exercise, or genetics can be thetrigger to this oxidant. Based on Chemotaxonomic,drugs that have been used to inhibit the oxidationprocess or termination stage of free radicals containthe active ingredient in the form of secondarymetabolites of alkaloids, phenolics, terpenoids andsteroids. For example, phenolic compounds such asflavonoids, xanthones, antioxidants and polyphenolsis a good agent because it has a structure with a highdegree of oxidation (Suares, et al, 2010).Researches related to the exploration of antioxidantactive ingredient has been more focused onsecondary metabolites found in terrestrial plants.The development of natural compounds potential ofmarine plant material such as mangrove are still notreceived much attention. Spalding et al. in 2001explained that mangroves plant in Indonesia is thehighest in the world, both in terms of quantity area(± 42 550 km2) as well as the number of species (±45 species). This basic natural resource of Indonesiamangrove is certainly valuable promisingopportunities to be expanded as a biological drug.Mangroves plant that commonly used as medicinediscovered from various species i.e: Acanthusilicifolius, Avicennia alba, Avicennia marina,Avicennia offinalis, Bruguiera cylindrical, Bruguieraexaristata, Bruguiera gymnorrhiza, Ceriops tagal,Hisbiscus tiliaceus, Ipomoea pes-capre, Lumnitzeraracemosa, Nypa fructicans, Pluchea indicaRhizophora apiculata, Rhizophora mucronata andSonneratia alba. Those plants are usually utilized asantiasma, antidiuretic, antidiabetic, reliever itching,and others. (Purnobasuki, 2004).The potential of mangroves as a drug is veryimportant to be developed considering the need fordrugs is increasing deals with the growing ofpopulation and many kinds of diseases such ascancer, hypertension, tumor diseases and diseasescaused by chemical or biological waste pollutionfrom viruses and bacteria. People are more likely tochoose drugs that are natural because relatively takefew side effects or even none at all.Several studies of mangrove plants from genusRhizophora that have antioxidant bioactivity areshown in the crude butanol extract of mangrove R.apiculata with IC50 33.34 pg / mL (Gao, 2012). Themethanol extract of R. mangle’s stem were alsodocumented to have antioxidant activity (Palacio, etal, 2014).One of mangroves found in Surabaya East Coastal(Pamurbaya), East Java, Indonesia is the mangroveRhizophora mucronata. This mangrove species isindigenous mangroves that ethno-botanicallypopular used as a pain reliever and dyes naturalwood. Secondary metabolites contained in theleaves, bark, stems, roots, and fruit are different inquantity. The content of secondary metabolites inplant commonly used as a medicine is from generalpart of the bark. Therefore, on the basis ofchemotaxonomic and ethno-botany of mangroves R.mucronata, this study aims to explore the bioactivityof antioxidant from the stem bark of R. mucronata.
Skopoletin Senyawa Fenilpropanoid dari Kulit Umbi Ubi Jalar (Ipomoea batatas L.) varietas IR-melati Pramitha, Citra Putri; Aminah, Nanik Siti; Kristanti, Alfinda Novi
Jurnal Kimia Riset Vol 1, No 2 (2016): Desember
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v1i2.3087

Abstract

AbstrakTelah berhasil diisolasi senyawa golongan fenilpropanoid dengan nama “skopoletin” dari kulit umbi ubi jalar (Ipomoea batatas L.). Ekstraksi senyawa dilakukan dengan metode maserasi menggunakan pelarut metanol, dilanjutkan dengan partisi menggunakan n-heksana dan etil asetat. Pemisahan dan pemurnian senyawa dilakukan menggunakan teknik kromatografi kolom gravitasi. Struktur senyawa dianalisis berdasarkan data spektroskopi UV/Vis, 1D, dan 2D-NMR. Kata kunci : fenilpropanoid, skopoletin, Ipomoea batatas L. AbstractIt has been isolated phenylpropanoid group compound named scopoletin from the tuber peel of Ipomoea batatas L. Extraction of this compound was done by maceration method using methanol solvent, followed by partition with n-hexane and ethyl acetate. Separation and purofication of compound was done by gravity column chromatography techniques. Structure of compound was analyzed by UV/Vis, 1D and 2D NMR spectroscopies. Keywords : phenylpropanoid, scopoletin, Ipomoea batatas L.
4-ETOKSI-3-METOKSIFENOL DAN METIL-3,4-DIHIDROKSIBENZOAT, DUA SENYAWA TURUNAN FENOLIK DARI EKSTRAK ETIL ASETAT KULIT UMBI GADUNG (Dioscorea hispida Dennst) DAN AKTIVITAS ANTIOKSIDAN EKSTRAK ETIL ASETAT Aminah, Nanik Siti; Kristanti, Alfinda Novi; Labibah, Qonitah; Firdausyah, Ana; Takaya, Yoshiaki
Jurnal Kimia Riset Vol 3, No 1 (2018): Juni
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v3i1.8873

Abstract

Two phenolic compoundnamely 4-ethoxy-3-methoxyphenol and methyl-3,4-dihydroxybenzoic have been isolated fromDioscorea hispida Dennst. The isolation of phenolic compounds was done by maceration methods using methanol, followed by partition with n-hexane and ethyl acetate. The process of separation and purification used various chromatography techniques including vacuum liquid chromatography, column chromatography, and radial chromatography. The structure of isolated compounds were determined by spectroscopic methods including UV-Vis, IR, 1D and 2D NMR. The ethyl acetate extract was evaluated for DPPH free radical scavenging activity assay. The IC50of ethyl acetate extract was 415 ppm. The result of this assay indicated that ethyl acetate extract has a potential as an antioxidant.  Keywords: Dioscorea hispida Dennst, Dioscoreaceae, phenolic, 4-ethoxy-3-methoxyphenol, methyl-3,4-dihydroxybenzoic, and antioxidant
THE EFFECTIVENESS OF HERBAL MOSQUITO COILS “MORIZENA” AGAINST Aedes Aegypti DEATH Susilowati, Rina Priastini; Darmanto, Win; Aminah, Nanik Siti
Indonesian Journal of Tropical and Infectious Disease Vol 7, No 2 (2018)
Publisher : Institute of Topical Disease

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v7i2.7324

Abstract

It has been successfully found new herbal mosquito coils called “Morizena” made from Passiflora foetida leaf extract (40%), Chrysantemum cinerariaefolium flowers seed extract (40%), essential oils of  leaves-stems of Cymbopogon nardus (20%). The herbal mosquito coils are more effective to kill Aedes aegypti compared to commercial synthetic mosquito coils made from Transfluthrin. Treatment of exposure to herbal mosquito coils “Morizena” on Aedes aegypti for 8 hours/day with concentration 500 ppm (P1), 1000 ppm (P2), 2000 ppm (P3), 3000 ppm (P4), 4000 ppm (P5) and treatment of exposure to synthetic mosquito coils Transfluthrin 2500 ppm (K1) as a positive control, and without treatment of exposure to mosquito coils (K0) as a negative control. Experimental animals used were adult Ae. aegypti mosquito with 25 mosquitoes in each treatment. Experimental design used is one-way Anova test with linear regression to calculate its LC50 and LC90. The results of test to herbal mosquito coils “Morizena” given for 8 hours/day obtained mortality of Ae. aegypti by 92% to a concentration of 3000 ppm (P4) and 100% to a concentration of 4000 ppm (P5) and 100% for test to synthetic mosquito coils transfluthrin 2500 ppm (K1). Ae. aegypti LC50 and LC90 value for treatment of exposure to herbal mosquito coils “Morizena” are 999 ppm and 2977 ppm. Treatment of herbal mosquito coils “Morizena” with graded doses up to 4000 ppm and synthetic mosquito coils Transfluthrin 2500 ppm causing an increase in the enzyme acetylcholinesterase activity of Ae. aegypti. The conclusion is based on the Ae. aegypti  LC90 value is 2977 ppm, which means the effective dose of herbal mosquito coils “Morizena” to kill Ae. aegypti is 2977 ppm.
(-)-AMPELOPSIN A : A DIMER RESVERATROL FROM Dryobalanops oblongifolia (dipterocarpaceae) Aminah, Nanik Siti; Achmad, Sjamsul Arifin; Niwa, Masatake; Syah, Yana Maolana; Hakim, Euis Holisotan
Indonesian Journal of Chemistry Vol 6, No 1 (2006)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.21778

Abstract

A dimer resveratrol compound named (-)-ampelopsin A was isolated from acetone extract of the stem bark of  Dryobalanops oblongifolia (Dipterocarpaceae). The structure of this compound was determined on the basis of NMR spectroscopic data.   Keywords: (-)-ampelopsin A, Dryobalanops oblongifolia, Dipterocarpaceae
SKOPOLETIN SUATU SENYAWA FENILPROPANOID DARI EKSTRAK ETIL ASETAT UMBI UBI JALAR (Ipomoea batatas L.) Aminah, Nanik Siti; Isma, Choirotul; Kristanti, Alfinda Novi
Jurnal Kimia Riset Vol 3, No 2 (2018): Desember
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v3i2.12061

Abstract

AbstrakTelah berhasil diisolasi senyawa golongan fenil propanoid  dengan nama “skopoletin” dari ekstrak etil asetat  umbi Ubi Jalar (Ipomoea batatas L.). Ekstraksi senyawa fenolik dilakukan dengan metode maserasi menggunakan pelarut metanol, dilanjutkan partisi menggunakan n-heksana dan etilasetat. Pemurnian dilakukan dengan kromatografi kolom gravitasi dan ktomatografi radial menghasilkan senyawa golongan fenil propanoid. Struktur skopoletin diidentifikasi berdasarkan data spektrum UV, 1D dan 2D NMR.Kata kunci : fenil propanoid, skopoletin, dan Ipomoea batatas L. AbstractPhenylpropanoid group compound has been isolated as “scopoletin” from ethylacetate extract of tuber flesh Sweet potatoes (Ipomoea batatas L.). Extraction of phenolic compound was done by maceration method using methanol solvent, then partition with n-hexana and  ethylacetate, respectively. The process of purification using various chromatographic techniques yielded compound of phenylpropanoid group. Structure of scopoletin is identified based on UV, 1D, and 2D NMR spectra.Keyword  : phenyl propanoid, scopoletin, dan Ipomoea batatas L.