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Postprandial Hypoglycemia Immanuel, Suzanna; Alvina, Alvina
Journal of the Indonesian Medical Association Vol. 59 No. 7 July 2009
Publisher : Journal of the Indonesian Medical Association

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Abstract

Postprandial hypoglycemia means hypoglycemia that occurred 2-5 hours after meal, which caused by excessive insulin secretion as a result of after meal increase of blood glucose. In contrast to normal condition blood glucose concentration after 2 hours of meal is higher than fasting. Postprandial hypoglycemia sometimes occurs without symptoms. This issue often raised by doctors that complained about false results from laboratory. In reality this condition happened due to postprandial glucose values not only it can be lower than during fasting but it could result in postprandial hypoglycemia. Symptoms may be observed namely tired, tremor, palpitation, irritability and even syncope. Postprandial hypoglycemia may be caused by drugs (e.g. salicylate, beta-blocker, pentamidine, ACE inhibitor, disophyramide), increased insulin sensitivity, early sign of diabetes mellitus (prediabetes), alcohol intake and post gastrectomy (alimentary hypoglycemia) and idiopathic. Laboratory tests for postprandial hypoglycemia include ambulatory glucose sampling, breakfast test or meal tolerance test. Diagnosis of hypoglycemia postprandial may be build if there are hypoglycemia symptoms after meal with postprandial blood glucose <50 mg/dL.Keywords: Postprandial hypoglycemia, insulin, prediabetes, idiopathic
Type IV collagen as marker of fibrosis in nonalcoholic liver disease Alvina, Alvina
Universa Medicina Vol 29, No 2 (2010)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2010.v29.114-122

Abstract

Currently nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are medical problems associated with the increasing prevalence of diabetes mellitus, obesity, hypertension and hypertriglyceridemia, usually designated as the metabolic syndrome associated with insulin resistance. One study demonstrated an increase in NAFLD prevalence of around 17-33% and in NASH prevalence of 5.7-16.5%. NAFLD comprises a range of mild to severe conditions, from simple steatosis to steatohepatitis, hepatic fibrosis and cirrhosis. The diagnosis of hepatic fibrosis is important for prognosis, stratification for treatment, and monitoring of treatment efficacy. Ultrasonography (USG) is a simple method for detecting fatty infiltrates in the liver. USG has a sensitivity of 82-89% and a specificity of 93%, but cannot differentiate between hepatic steatosis and fibrosis. The gold standard for evaluation of hepatic fibrosis is liver biopsy, which however is a painful and invasive procedure. Currently determination of serum type IV collagen has been suggested as an alternative to liver biopsy among the non-invasive methods for evaluation of hepatic fibrosis, as its serum concentration is closely correlated with advanced hepatic fibrosis in NASH. Type IV collagen is one of the components of basement membrane and its serum concentration is indicative of degradation of the extracellular matrix.
Hepatic enzyme concentrations as indicators of nonalcoholic fatty liver disease Alvina, Alvina
Universa Medicina Vol 28, No 3 (2009)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2009.v28.139-145

Abstract

Nonalcoholic fatty liver disease (NAFLD) has emerged as a world-wide problem because it runs an asymptomatic course, ultimately leading to cirrhosis of the liver and portal hypertension, resulting in death. The prevalence of the disease accounts for 3-24% of the population in several countries. Generally there are increased concentrations of hepatic enzymes as markers of liver damage, such as serum glutamic oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT) and gamma glutamyl transferase (GGT). The aim of the present study was to determine the concentrations of hepatic enzymes as markers of NAFLD. The study design was cross-sectional, involving 90 subjects meeting the inclusion and exclusion criteria. The degree of severity NAFLD was determined by ultrasonography and the concentrations of SGOT, SGPT and GGT by automated clinical chemistry analyzer. The results indicated that there were 32 subjects with mild NAFLD (35.6%), 35 subjects with moderate NAFLD (38.9%) and 23 subjects with severe NAFLD (25.6%). There was a significant difference in degree of NAFLD by gender (p<0.05), where severe NAFLD was more frequent in males than in females. Concentrations of SGOT, SGPT and GGT were significantly different between degrees of NAFLD (p<0.05). The conclusion is that SGOT, SGPT and GGT concentrations are indicators of degree of NAFLD.
Glycated albumin for glycemic control of diabetic patients on hemodialysis Alvina, Alvina
Universa Medicina Vol 33, No 1 (2014)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2014.v33.1-2

Abstract

Regular assessment of glycemic control in diabetic patients is very important, because it reduces the incidence of complications and determines prognosis and quality of life of the patients.(1) Uncontrolled and advanced diabetes may lead to complications, such as kidney disease, heart attacks, and stroke, which are on the increase worldwide. Patients with diabetic nephropathy account for almost 50% of dialysis patients in the US, while cardiovascular disease is the main cause of death of patients with complicated diabetes.(2)
Idiopathic thrombocytopenic purpura: laboratory diagnosis and management Alvina, Alvina
Universa Medicina Vol 30, No 2 (2011)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2011.v30.126-134

Abstract

Idiopathic thrombocytopenic purpura (ITP) or immune thrombocytopenic purpura is a disease characterized by low platelet count (<150,000/ìL) caused by autoantibody-mediated platelet destruction and the absence of other causes of thrombocytopenia. Acute primary ITP is more common in children 2-6 years of age, with similar incidence between males and females, while the chronic form is usually encountered in adults with median age of 40-45 years. The clinical signs of ITP are purpura, ecchymosis, petechiae and gastrointestinal tract bleeding, gingival bleeding, epistaxis, and urinary tract bleeding. Spontaneous mucosal, intracranial, and gastrointestinal hemorrhage may occur at platelet counts of <10000/ìL. To date, the diagnosis of ITP is still arrived at by exclusion, i.e. by elimination of other causes of thrombocytopenia. The diagnosis of ITP also requires a medical history (anamnesis), physical examination, platelet count, and examination of a peripheral blood smear. The latter examination in ITP shows low numbers of normal-sized platelets, occasionally also giant platelets, while erythrocytes and leukocytes have a normal morphology. The bone marrow is usually normal or shows increased megakaryocytes. Assessment of antithrombocyte antibody may assist in establishing the diagnosis of ITP. Management of ITP is based on platelet count and severity of bleeding. Treatment is aimed at interfering with antibodies that damage the platelets, by inhibiting the functions of macrophage Fcã receptors and decreasing the production of antiplatelet antibodies. Thrombopoietin (TPO) receptor agonists including eltrombopag and romiplostim have offered an important new option in treating ITP.
PERBEDAAN MORDAN BELIMBING MANIS (Avverhoa Carambola) DAN BELIMBING WULUH (Avverhoa Bilimbi) TERHADAP HASIL PENCELUPAN PADA BAHAN SUTERA MENGGUNAKAN EKSTRAK BIJI KESUMBA (Bixa Orellana L) Alvina, Alvina; Adriani, Adriani; Novrita, Sri Zulfia
E-Journal Home Economic and Tourism Vol 12, No 2 (2016): Priode Mei 2016
Publisher : E-Journal Home Economic and Tourism

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Abstract

This study aimed to describe the name of the color (hue), light and dark colors (Value) and flatness of color for silk dyeing results using crimson seed extract (Bixa Orellana l) with mordant sweet star fruit and starfruit. This research is an experimental research. The data used are primary data sourced from 15 panelists, then the collected data is processed and analyzed using ANOVA and Percentage. Dyeing silk with crimson seed extract (Bixa Orellana l) without mordant produce Mineral Orange color with a value reasonably bright and flatness of color is quite average. Mordan sweet star fruit is Peach with bright value and average color flatness and mordant starfruit is Light Peach with a value very bright and flatness of color is very flat. The results of the data analysis of light and dark colors (value) indicates F count> F table = 3.320> 3. 22 This means that there is a significant difference to the light and dark colors (value) due to differences mordant. At the flatness of the color indicates Fhitung> Ftable = 9599> 3.22 means that there is a significant difference to the flatness of color due to differences mordant. Kata Kunci : Perbedaan Mordan, Ekstrak Biji Kesumba
Pengaruh Kualitas Audit, Debt Default (Kegagalan Hutang) dan Ukuran Perusahaan terhadap Penerimaan Opini Audit Going Concern pada Subsektor Perusahaan Tekstil & Garment Yang Terdaftar Di Bursa Efek Indonesia pada Periode 2014-2017 Chandra, Irene; Cianata, Steven; Rahmi, Namira Ufrida; Zai, Fansra Septiman; Alvina, Alvina; Batubara, Maisara
Owner Vol 3 No 2 (2019): Owner Volume 3 Nomor 2 Agustus 2019
Publisher : Politeknik Ganesha Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33395/owner.v3i2.124

Abstract

Going concern audit opinion is an audit opinion with an explanatory paragraph regarding an auditor consideration that has an inability or significant uncertainty on operating a company life sustainability in the future time. There are many factors that affect going concern audit opinion which are Audit Quality, Debt Default, and Firm Size. The purpose of this research is to examine and to analyze the effect of Audit Quality, Debt Default, and Firm Size toward Revenues Going Concern Audit Opinion on the company subsector of textile and garment listed on the Indonesia Stock Exchange in 2014-2017. The types of data collections are descriptive statistics with a quantitative approach. The method of collective data used documentation study and logistic regression analysis. Using the population-based on the financial statement of textile and garment companies that are listed on the Indonesia Stock Exchange in 2014-2017. The technique which used for sampling is purposive sampling method. The result of this study showed that Audit Quality, Debt Default, and Firm Size have the simultant effect of Revenues Going Concern Audit Opinion with a significant value 0.010 < 0.05. Audit Quality and Firm Size did not affect Revenues Going Concern Audit Opinion partially. Debt Default effect the Revenues Going Concern Audit Opinion