Nur Illiyyin Akib
Jurusan Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Haluoleo, Kendari

Published : 8 Documents
Articles

Found 2 Documents
Search
Journal : Medula

PREPARASI FENILBUTAZON DALAM PEMBAWA VESIKULAR ETOSOM DENGAN BERBAGAI VARIASI KONSENTRASI FOSFATIDILKOLIN DAN ETANOL

Medula Vol 2, No 1 (2014)
Publisher : Medula

Show Abstract | Original Source | Check in Google Scholar | Full PDF (392.986 KB)

Abstract

Phenylbutazone is non steroidal anti-inflammatory drug (NSAID) used  in treatment of joint inflammation such  as  rheumathoid  arthritis.  In  order  to  minimize  irritation  effect  on  gastrointestinal  tract,  the  dose  of phenylbutazone is reduced or administered through transdermal pathways. Flux penetration of drugs across the membrane  can  be  improved  by  using  vesicular  type  of  delivery  system  such  as  ethosome.  This  study  aim  to prepare  phenylbutazone in  ethosome  vesicular  system.  Ethosome vesicular  systems  were prepared  with  various concentrations  of  phosphatidylcholine  (2%  and  3%)  and  ethanol  (30%,  35%,  and  40%).  Vesicles  that  are formed  further  characterized  by  shape,  size  and  entrapment  efficiency.  The  shaped  of  ethosome  produced  is large  unilamellar vesicle.  The size of vesicle  varies  between  0.57 to 0.81  µm  with  the smallest size  on Formula C.  The  highest  entrapment  efficiencies  was  also  on  the  Formula  C  by  59.88%  with  2%  concentration  of phosphatidylcholine and 40% of ethanol. Keywords: phenylbutazone, vesicle, ethosomes.

EVALUASI MUTU PELAYANAN DAN HUBUNGAN ANTARA KEPUASAN KONSUMEN DAN PELAKSANAAN PELAYANAN KEFARMASIAN OLEH APOTEKER PENGELOLA APOTEK DI APOTEK-APOTEK KOTA KENDARI

Medula Vol 2, No 1 (2014)
Publisher : Medula

Show Abstract | Original Source | Check in Google Scholar | Full PDF (426.71 KB)

Abstract

Pharmaceutical service  quality relate to consumer’s  satisfaction.  Twenty five percent   curage  of patient can be  found  from  good  pharmaceutical  sevice  and  75%  from  drug  usage.  This  study  aimed  to  determine pharmaceutical  service  quality  in  community  pharmacy  of  Kendari  City  and  to  determine  correlation  between  consumer’s  satisfaction  and  implementation  of  pharmaceutical  service  by  pharmacist  manager.  This  study  is  an observational analytic. Data collected from 519 respondents  through questionnaires in June-August 2014 spread across  ten  community  pharmacies  City  of  Kendari  with  sampling  method  used  simple  random  sampling,  and accidental  sampling  for  pharmacist  manager.  Correlation  test  used  to  determine  correlation  between  cons umer satisfaction and implementation of pharmaceutical care by pharmacist manager in pharmacy. The result showed that the percentage rate is 76.70% for consumer satisfaction with moderate category. Fixed percentage of any document procedures  and  dispensing  time  is  60%  with  moderate  category.  Pharmacist  manager  percentage  that  manages quality guarantee is 40% with less category.  Statistic correlation test showed that there is no cerrelation between consumer satisfaction and implementation of pharmaceutical care by pharmacist manager in pharmacy with p value 0,268 (> 0,05). Keywords: quality service, pharmaceutical service, consumer satisfaction