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EFFECT OF ETHANOL EXTRACT SAMBILOTO LEAF (Andrographidis folium) AGAINST BLOOD GLUCOSE LEVEL IN MALE Swiss Webster MICE INDUCED BY ALOXAN COMPARED TO JAMU D -, Rosnaeni; Ratnawati, Hana; Kastilani, Sarah
Jurnal Medika Planta Vol 1, No 1 (2010)
Publisher : Jurnal Medika Planta

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 Introduction: Jamu D is Indonesian traditional medicine containing ethanol extract of sambiloto leaf (EESL) which can be used as diabetes mellitus alternative drug. The aim of this study is to know the effect of EESL in lowering blood glucose levels comparde to Jamu D. Methods :The real prospective experimental comparative with complete randomized design was done. Twenty four aloxan induced diabetic male Swiss Webster mice was divided into 6 groups of treatment i.e. EESL dose 1 (29.25 mg/ kgBW), EESL dose 2 (58.5 mg/ kgBW), EESL dose 3 (117 mg/ kgBW),  control (CMC 1% suspension), comparator (Glibenklamid 0.65 mg/ kgBW), Jamu D (195 mg/ kgBW) for 7 days. The fasting blood glucose level was examined at the eight day and blood glucose level decrease percentage was analyzed with ANOVA, continued with Tukey HSD, a = 0.05. Results: showed that the decrease of blood glucose level in EESL dose1(65.93 %), dose (66.66 %), was same with Jamu D (59.82 %)(p >0,05) while the decrease percentage in dose 2 was significant different with Jamu D (p < 0,01). Conclusions :  EESL dose 1 and dose 3 were as effective as Jamu D in decreasing blood glucose level while dose 2 was not effective 
REPPELENT EFFECT OF LAVENDER, ROSE AND ROSEMARY OIL ON Aedes aegypti MOSQUITOES Hidayat, Meilinah; -, Rosnaeni; Hendranata, Katrin Fitria
Jurnal Medika Planta Vol 1, No 1 (2010)
Publisher : Jurnal Medika Planta

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Introduction :Dengue Haemmorhagic Fever (DHF) was one of arthropode borne diseases which was spread by mosquitoes. To prevent insect bites we could use synthetic repellent like diethyltoluamid (DEET). DEET usages for long time period could cause many side effects so we needed to seek natural repellent which was safe and effective. Objective : to know the potential effect of lavender, rose and rosemary  oil repellent to adult female Aedes aegypti mosquitoes. Methods :The research design was true experimental with Complete Random Sampling, comparatively. The effects of reppelents were examined by using one side method. Seven hundred and fifty  Aedes aegypti mosquitoes which were separated into 5 groups, were given treatment randomly with of lavender, rose, rosemary  oil, control and DEET 12.5%. Data were measured by counting the number  of mosquitoes which migrated from the side that had been given treatment. Data were analyzed by using ANOVA one way, continued with Tukey HSD test, α = 0,05 using computer software. Results :This study showed the amount of mosquitoes which migrated from the side which had been given lavender oil was 89.33%, rose oil  92,67%, rosemary  oil 94,00% highly different significant  (p<0,01) from control 8.67%. Conclusion was lavender, rose, and rosemary  oil had potential effects as repellents. The potential effects of rose, and rosemary  oil were similar  to DEET 12,5 % (p>0,05), but lavender oil was lower than DEET 12,5 % (p<0,05).