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PROFIL PENDERITA SEPSIS AKIBAT BAKTERI PENGHASIL ESBL

journal of internal medicine Vol. 13, No. 1 Januari 2012
Publisher : journal of internal medicine

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Abstract

Extended Spectrum !-Lactamases (ESBL) is plasmid enzyme which catalyzing hydrolysis and inactivation !-lactamantibiotic, including third generation of Cephaloporin, penicillin and aztreonam. This enzyme is mutation of !-lactamaseTEM-1, TEM-2, and SHV-1 which commonly found in Enterobacteriaceae and normally have resistance to penisillin andrst generation celaphorin. The incidence of infection cause by ESBL bacterial is increasing worldwide. AntimicrobialResistance in Indonesia: prevalence and prevention (AMRIN study) is showed incidence of infection ESBL bacterial 29%E. coli, and 36% K. pneumonia. This study is descriptive and restrospectively learn about prole of DMK with septicemiapatient caused by ESBL bacterial in Internal Medicine Ward RSUD Dr Soetomo within 1st January 2010 until 30th June2011. Sixty four patient were recruited and 48 patients with ESBL bacterial positive. Mortality rate is 16.7%, severe septiccondition 27.08%, septic shock 14.58%. The result of positive ESBL bacterial was found from urine culture (37.5%).Sensitivity of antibiotics results are meropenem (98.07%), amikacin (88.46%).

Formulasi Deterjen Berbahan Aktif Etil Ester Sulfonat dari Minyak Biji Ketapang (Terminalia cattapa) dengan Penambahan Enzim Papain

Jurnal Sains dan Teknologi Kimia Vol 4, No 2 (2013): Jurnal Sains dan Teknologi Kimia
Publisher : Program Studi Kimia Jurusan Pendidikan Kimia FPMIPA UPI

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Abstract

Enzim papain merupakan salah satu enzim protease yang dapat dijadikan sebagai additive pada formulasi deterjen. Protease dalam deterjen secara spesifik membantu menghilangkan protein yang menodai pakaian. Penelitian ini bertujuan untuk mengkaji pengaruh penambahan enzim papain terhadap karakteristik deterjen berbahan aktif etil ester sulfonat dari minyak biji ketapang (Terminalia cattapa).    Karakteristik  deterjen  yang  ditentukan  meliputi:  Bahan  tidak  larut dalam  air,  Stabilitas  emulsi,  dan  Stabilitas  busa.  Hasil  penelitian  merupakan bahan tidak larut dalam air dari deterjen   tanpa papain dan deterjen dengan konsentrasi papain  1, 3, 5, 7, dan 9% (b/b)  berturut-turut sebesar 6; 6; 5; 4; 5, dan 4%. Stabilitas emulsi deterjen tanpa papain dan deterjen dengan konsentrasi papain 1, 3, 5, 7, dan 9% (b/b) berturut-turut adalah 93,05; 90,20; 90,70; 94,55; 94,60 dan 96,05% dan Stabilitas busa deterjen tanpa penambahan papain dan deterjen enzimatik dengan penambahan konsentrasi papain 1, 3, 5, 7, dan 9% (b/b) berturut-turut adalah 83,33; 70,00; 78,33; 78,59; 73,64, dan 77,50%.  Penambahan enzim papain pada deterjen hasil formulasi menggunakan surfaktan etil ester sulfonat dari minyak biji ketapang berpengaruh terhadap karakteristik deterjen yang meliputi bahan tidak larut dalam air, stabilitas emulsi, dan stabilitas busaKata kunci: Deterjen, Terminalia cattapa, papain.

Context, Input, Process, Product Analysis in the Implementation of Iron Supplementation Program in Banyumas, Central Java

Journal of Health Policy and Management Vol 1, No 2 (2016)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Iron supplementation program has been implemented in Banyumas, District, Central Java, but the prevalence of anemia in pregnant women remains as high as 55.37%. The Banyumas District Health Office has launched an ad hoc (temporary) iron supplementation program, namely Hemafort, in order to reduce anemia prevalence. This study aimed to investigate the factors that determine the effectiveness of the iron supplementation program for pregnant women in Banyumas, Central Java.Subjects and Method: This was a qualitative study with case study approach, and CIPP (context, input, process, product) framework. This study was conducted Wangon II and South Purwokerto Health Centers from October to November 2016. Informants were selected by purposive sampling including midwives, nutritional program managers, pharmacists, head of nutrition section, and pregnant women. The data were collected by in-depth interview, observation, and archival review. The data were analyzed by a multiple case study. The data were validated by data source triangulation.Results: The iron tablets coverage for pregnant women reached 94.88% and 89.26% in 2014 and 2015, respectively, in Banyumas. The minimal target of iron coverage for pregnant women was 90%. There was no local government policy or standard operating procedure (SOP) that regulated the efforts to tackle anemia problems in pregnant women. The number of health personnel in charge of nutrition and their competence were sufficient. But reliable budget to tackle anemia problem did not exist. Spending district budget was an exit strategy to take when there was deficiency in central budget allocation. The number of iron supplementation tablets was not guaranteed.Conclusion: The effectiveness of iron supplementation program for pregnant women depends on the existence of relevant policy, SOP, allocation of sufficient and reliable budget, as well as adequate supply of iron tablets.Keywords: iron supplementation tablets, pregnant women, local government, budgetCorrespondence: Purwati. Faculty of Health Sciences, Muhammadiyah University at Purwokerto, Central Java. Email: watix_1006@yahoo.com. Mobile: +6285735145236.Journal of Health Policy and Management (2016), 1(2): 113-120https://doi.org/10.26911/thejhpm.2016.01.02.06