NOVIANI, YUSLIA
Fakultas Farmasi Universitas Indonesia

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Pengaruh Variasi Konsentrasi Polivinil Alkohol (PVA) pada Formulasi Masker Gel Peel-Off Ekstrak Belimbing Wuluh (Averrhoa Bilimbi L.) sebagai Anti Jerawat NOVIANI, YUSLIA; NOOR, SITI UMRAH; NENGSIH, ERNI
JURNAL ILMU KEFARMASIAN INDONESIA Vol 14 No 2 (2016): JIFI
Publisher : Fakultas Farmasi Universitas Indonesia

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Abstract

Star fruit (Averrhoa bilimbi L.) can be used as anti acne because of flavonoid content, which is active to inhibiting the growth of Propionibacterium acnes bacteria. The extract of star fruit at concentration 8% have 8-9 mm diameter inhibition, then formulated become a peel-off mask gel with the doses of extract at 8% as anti acne. The preparation of peel-off mask gel made in three formula with PVA variations, there are 10%, 12% and 14%; were made by dissolving and mixing method. The evaluation of the preparation are including homogeneity, the visual observation, elongation, the drying time, viscosity, rheology and the activity of inhibition againts the growth of Propionibacterium acnes bacteria in microbiologycal assay.
EFFECT OF DRYING TECHNIQUE ON PHYSICAL QUALITY AND ANTI-INFLAMMATORY ACTIVITY OF WILD BETEL LEAVES (Piper sarmentosum Roxb. ex Hunter) EXTRACT Fahleni, Fahleni; Noviani, Yuslia; Ramadhani, Syarifah
JURNAL ILMU KEFARMASIAN INDONESIA Vol 16 No 1 (2018): JIFI
Publisher : Fakultas Farmasi Universitas Indonesia

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Abstract

Kaduk betel leaves (Piper sarmentosum Roxb. ex. Hunter) contain flavonoids and alkaloids that have anti-inflammatory activity. Processing thick extract into a dry extract is required to determine the appropriate dose and increase the homogeneity. The purpose of tahhis study was to determine the effect of drying method to physical properties of dried powder and its antiinflammatory activity. Thick extract was dried using maltodextrin and lactose as adsorbents with concentrations of extract-adsorbent ratio  1: 1, 1: 2 and 1: 3. Method of drying were freeze drying and adsorbent. The evaluation results based on organoleptic dried powder, water content and flow properties. The water content of dried powder which is dried by freeze drying is smaller than that of  the adsorbent. Organoleptic and flow properties of freeze dried powder results were also better. The best dried powder in each method tested its anti-inflammatory activity using BSA. The test results showed that the anti-inflammatory activity of dried extract of freeze drying (extract-maltodextrin 1:3)  have higher activity with IC50 551.79 ppm compared to dried extract with adsorbent (extract-maltodextrin 1:3) 598.30 ppm.
PENGARUH JENIS LEMAK ALKOHOL SEBAGAI PENGENTAL TERHADAP STABILITAS FISIK SEDIAAN KONDISIONER RAMBUT BILAS (RINSE-OFF HAIR CONDITIONER) YANG MENGANDUNG EKSTRAK BUAH KIWI (Actinidia chinensis P.) Noviani, Yuslia; Noor, Siti Umrah; Raihanah, Raihanah
Jurnal Farmasi Indonesia Vol 10, No 2 (2018)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (723.373 KB) | DOI: 10.35617/jfi.v10i2.607

Abstract

Buah kiwi telah digunakan untuk perawatan rambut karena kandungan vitamin C, vitamin E dan arginin yang bermanfaat menjaga kesehatan rambut, membantu meningkatkan sirkulasi di kulit kepala dan melembutkan serta menutrisi rambut. Telah dilakukan penelitian formulasi sediaan untuk perawatan rambut yakni kondisioner rambut bilas (rinse-off hair conditioner) yang mengandung ektrak buah kiwi sebanyak 8 formula dengan variasi jenis lemak alkohol (setil alkohol, stearil alkohol, setostearil alkohol dan behenil alkohol) dengan konsentrasi masing-masing 4% untuk mendapatkan formula sediaan kondisioner rambut bilas dengan satu jenis lemak alkohol yang menghasilkan viskositas yang sesuai dan stabil secara fisik. Sediaan ini dibuat dengan cara pemanasan pada suhu 70-80oC dan pencampuran antara fase minyak dan fase air, yaitu fase minyak dicampurkan ke dalam fase air. Sediaan yang dihasilkan dievaluasi secara fisik dan kimia meliputi uji organoleptik, homogenitas, tipe emulsi, viskositas dan sifat alir, sentrifugasi dan ukuran partikel serta pH.